Cholinesterase - koko

ʻO ka cholumesterase serum kahi hōʻike i ke koko e nānā i nā pae o 2 mau mea e kōkua pono i ka ʻōnaehana hopohopo. Kapa ʻia lākou he acetylcholinesterase a me pseudocholinesterase. Pono kou aʻa i kēia mau mea e hoʻouna i nā hōʻailona.

ʻIke ʻia ka acetylcholinesterase i nā aʻa nerve a me nā ʻulaʻula o ke koko. ʻO Pseudocholinesterase ka mea i ʻike nui ʻia i ke ake.

Pono kahi laʻana koko. ʻO ka hapanui o ka manawa e huki ʻia ke koko mai kahi aa i waiho ʻia ma loko o ka kuʻe lima a i ʻole ka hope o ka lima.

ʻAʻole pono nā kapuaʻi kūikawā e hoʻomākaukau ai no kēia hōʻike.

Hiki paha iā ʻoe ke ʻeha iki a i ʻole ke kuʻi ke hoʻokomo ʻia o ka nila. Hiki paha iā ʻoe ke hāwele i kahi kani ma ka pūnaewele ma hope o ka huki ʻia ʻana o ke koko.

E kauoha paha kāu mea mālama mālama ola i kēia hoʻāʻo inā ʻike ʻia ʻoe i nā kemika i kapa ʻia he organophosphates. Hoʻohana ʻia kēia mau kemika i nā pesticides. Hiki i kēia hoʻāʻo ke kōkua i ka hoʻoholo i kāu makaʻu i ka lāʻau make.

Emi pinepine, e hana i kēia ho'āʻo:

• E hōʻoia i ka maʻi maʻi ate
• Ma mua o ka loaʻa ʻana o ka anesthesia me ka succinylcholine, i hāʻawi ʻia ai ma mua o kekahi mau kaʻina hana a i ʻole nā ​​mālama ʻana, e like me ka electroconvulsive therapy (ECT)

ʻO ka maʻamau, aia nā helu pseudocholinesterase maʻamau ma waena o 8 a 18 mau mīkini i kēlā me kēia milliliter (U / mL) a i ʻole 8 a me 18 mau kilokika ma kēlā me kēia lita (kU / L).

Kaha: hiki ke loli iki i nā pae waiwai maʻamau ma waena o nā hale hana ʻokoʻa. E kamaʻilio i kāu mea hāʻawi e pili ana i ke ʻano o kāu mau hopena hōʻike.

ʻO nā pae pseudocholinesterase i hōʻemi ʻia ma muli o:

• Maʻi maʻi maʻi
• Kaʻai kūpono ʻole
• Maʻi hohola
• Poino ke ake
• ʻO Metastasis
• Jaundice ālai
• Poisoning mai organophosphates (nā kemika i loaʻa i kekahi pesticides)
• ʻO ka mumū e pili pū ana me kekahi mau maʻi

Hoʻemi ʻia nā hōʻemi liʻiliʻi no:

• Hapai keiki
• Hoʻohana o nā lāʻau kaohi hānau

ʻO Acetylcholinesterase; RBC (a i ʻole erythrocyte) cholinesterase; Pseudocholinesterase; Plasma cholinesterase; Butyrylcholinesterase; Serum cholinesterase

• Hōʻike Cholinesterase

Aminoff MJ, No laila ʻo YT. Nā hopena o nā toxins a me nā ʻākena kino i ka ʻōnaehana hopohopo. I: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, eds. ʻO Bradley's Neurology i ka hana lapaʻau. ʻEpekema 7 Piladelapia, PA: Elsevier; 2016: chap 86.

ʻO Nelson LS, Ford MD. Lāʻau make ʻino. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 25th hua. Piladelapia, PA: Elsevier Saunders; 2016: chap 110.