Atrophy ʻōnaehana lehulehu - subebype cerebellar

Atrophy ʻōnaehana lehulehu - cerebellar subtype (MSA-C) kahi maʻi laha ʻole e kumu i nā wahi hohonu i ka lolo, ma luna pono o ka iwi kuamoʻo, e hoʻoliʻiliʻi (atrophy). Ua kapa ʻia ʻo MSA-C ma ke ʻano he atrophy olivopontocerebellar (OPCA).

Hiki ke hoʻoiho ʻia ʻo MSA-C ma waena o nā ʻohana (palapala hoʻoilina). Hiki iā ia ke hoʻopili i ka poʻe me ka ʻole o ka mōʻaukala ʻohana i ʻike ʻia (form sporadic).

Ua hoʻomaopopo nā kānaka noiʻi i kekahi mau ʻiʻo e pili ana i ke ʻano hoʻoilina o kēia ʻano.

ʻO ke kumu o MSA-C i ka poʻe me ka sporadic form ʻaʻole ʻike ʻia. Hele a māliʻi ka maʻi (holomua).

ʻOi aku ka maʻamau o MSA-C i nā kāne ma mua o ka wahine. ʻO ka makahiki maʻamau o ka hoʻomaka ʻana he 54 mau makahiki.

Hoʻomaka ka hoʻomaka ʻana o nā ʻōuli o MSA-C i ka wā ʻōpio i ka poʻe me ka palapala hoʻoilina. ʻO ka hōʻailona nui ka clumsiness (ataxia) e hele lohi ai ka maikaʻi. Aia paha kekahi mau pilikia me ke kaulike, ka lohi o ka ʻōlelo, a me ka paʻakikī e hele wāwae.

Hiki i nā ʻōuli ʻē aʻe ke:

• Nā neʻe maka ʻole
• Nā neʻe maʻamau
• Nā pilikia ʻōpū a ʻōpū paha
• Pilikia i ka ale ʻana
• Nā lima me nā wāwae anuanu
• ʻĀlohilohi ke kū
• ʻEha ke poʻo i ke kū ʻana i hoʻomaha ʻia e ka moe ʻana i lalo
  
• ʻOʻoleʻa ka ʻili a i ʻole ʻoʻoleʻa, spasms, haʻalulu
• Poino ke nerve (neuropathy)
• Nā pilikia i ka kamaʻilio ʻana a me ka hiamoe ʻana ma muli o nā spasms o nā kaula leo
• Nā pilikia pili i ka moekolohe
• ʻO ka hou sweating maʻamau

ʻO ka loiloi olakino a me ka ʻōnaehana ʻōnaehana pono, a me kahi loiloi e pono ai a me ka mōʻaukala ʻohana e pono ai ka hōʻailona.

Aia nā hoʻokolohua kūlohelohe e nānā i nā kumu o kekahi ʻano o ka maʻi. Akā, ʻaʻohe hōʻike kikoʻī i loaʻa i nā manawa he nui. Hōʻike paha kahi MRI o ka lolo i nā loli i ka nui o nā hanana lolo i hoʻopilikia ʻia, ʻoiai ke hele a nui ka maʻi. Akā hiki ke loaʻa ka maʻi a loaʻa kahi MRI maʻamau.

Nā hoʻokolohua ʻē aʻe e like me ka positron emission tomography (PET) hiki ke hana ʻia e kāpae i nā kūlana ʻē aʻe. Pili pū paha kēia i nā noi ʻana e ale inā hiki i ke kanaka ke ale pono i ka meaʻai a me ka wai.

ʻAʻohe mālama kūikawā a lāʻau paha no MSA-C. ʻO ka pahuhopu ka mālama ʻana i nā ʻōuli a pale i nā pilikia. Hoʻopili paha kēia:

• Nā lāʻau lapaʻau haʻalulu, e like me nā maʻi Parkinson
• ʻO ka haʻi ʻōlelo, ka ʻoihana a me ka hoʻōla kino
• Nā ala e pale ai i ke kolo ʻana
• ʻO nā kōkua hele wāwae e kōkua me ke kaulike a pale i ka hāʻule

Hiki i nā hui aʻe ke hāʻawi i nā kumuwaiwai a me ke kākoʻo no ka poʻe me MSA-C:

• Hoʻohaʻahaʻa i ka MSA Alliance --ildmsa.org/patient-programs/
• ʻO ka Coalition MSA - www.multceptsystematrophy.org/msa-resource/

Maikaʻi mālie ʻo MSA-C, a ʻaʻohe lāʻau. Maʻilihune ka nānā ʻana i waho. Akā, mau makahiki paha i hala ma mua o ke kīnā ʻana o kekahi.

ʻO nā pilikia o MSA-C pū kekahi:

• Kāpena
• ʻO ka maʻi mai ka hanu ʻana i ka meaʻai i loko o nā māmā (aspiration pneumonia)
• ʻO ka ʻeha mai ka hāʻule
• Nā pilikia kūpono no ka pilikia i ka ale ʻana

Kāhea i kāu mea mālama ola inā loaʻa iā ʻoe nā ʻōuli o MSA-C. Pono ʻoe e ʻike ʻia e kahi neurologist. ʻO kēia kahi kauka nāna e mālama i nā pilikia ʻōnaehana.

MSA-C; Cerebellar mau ʻōnaehana atrophy; Atrop Olivopontocerebellar; OPCA; Olivopontocerebellar hoʻohaʻahaʻa

• ʻŌnaehana ʻōnaehana waena a me ka ʻōnaehana ʻōnaehana peripheral

Ciolli L, Krismer F, Nicoletti F, Wenning GK. Hoʻohou i ka cerebellar subtype o nā ʻōnaehana atrophy. Cerebellum Ataxias. 2014; 1-14. PMID: 26331038 pubmed.ncbi.nlm.nih.gov/26331038/.

Gilman S, Wenning GK, Low PA, et al. ʻO ka ʻōlelo kuʻikahi ʻelua e pili ana i ka hōʻailona o ke atrophy ʻōnaehana he nui. Neurology. 2008; 71 (9): 670-676. PMID: 18725592 pubmed.ncbi.nlm.nih.gov/18725592/.

ʻO ka maʻi ʻo Jancovic J. Parkinson a me nā ʻano neʻe ʻē aʻe. I: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, eds. ʻO Bradley's Neurology i ka hana lapaʻau. ʻEpekema 7 Piladelapia, PA: Elsevier; 2016: chap 96.

Ma MJ. ʻO nā maʻi biopsy o nā maʻi neurodegenerative i nā mākua. I: Perry A, Brat DJ, eds. ʻO ke Neuropathology Surgical Practical: Ke Alakaʻi Diagnostic. ʻElua ed. Piladelapia, PA: Elsevier, 2018: chap 27.

Walsh RR, Krismer F, Galpern WR, a me al. Nā ʻōlelo paipai o ka hālāwai kūkā alanui noiʻi atrophy ʻōnaehana o ka honua. Neurology. 2018; 90 (2): 74-82. PMID: 29237794 pubmed.ncbi.nlm.nih.gov/29237794/.