Amyloidosis ʻōnaehana lua

Amyloidosis ʻōnaehana kekona kahi maʻi kahi e kūkulu ʻia ai nā polokina ʻino i loko o nā aʻa a me nā meaola. Kapa ʻia nā ʻōpala o nā protein pono ʻole i nā waihona amyloid.

ʻO ke ʻano kiʻekiʻe ʻo ia ka hopena ma muli o kekahi maʻi a i ʻole kahi hanana. ʻO kahi laʻana, hana maʻamau kēia ʻano ma muli o ka maʻi lōʻihi (mau) a me ka mumū. I ka hoʻohālikelike ʻana, ʻo ka amyloidosis mua ʻaʻohe kumu o nā maʻi ʻē aʻe e hoʻokumu i kēia ʻano.

ʻO ke ʻano o ka ʻōnaehana ka hopena o ka maʻi i ke kino holoʻokoʻa.

ʻAʻole ʻike ʻia ke kumu kūpono o ka amyloidosis ʻōnaehana kekona. Hiki paha iā ʻoe ke hoʻomohala i ka amyloidosis ʻōnaehana lua inā loaʻa iā ʻoe kahi maʻi lōʻihi a mumū paha.

Kūpono kēia ʻano me:

• ʻO ka Ankylosing spondylitis - kahi ʻano o ka arthritis e pili nui i nā iwi a me nā hono i ka iwi kuamoʻo
• ʻO Bronchiectasis - maʻi i hōʻino ʻia nā ala ākea i loko o nā akemama e ka maʻi mau
• Osteomyelitis maʻi - maʻi maʻi iwi
• ʻO Cystic fibrosis - maʻi e hana ai i nā mānoanoa, pākuʻi mucus e kūkulu i loko o nā akemāmā, nā ʻōnaehana digestive, a me nā wahi ʻē aʻe o ke kino, e hiki ai i ka maʻi mau o nā akemāmā
• ʻO ka wela a ka ʻohana Mediterranean - hoʻoilina hoʻoilina o nā fiva pinepine a me ka mumū e pili pinepine i ka uhi o ka ʻōpū, ka umauma, a me nā hono
• Leukemia pūnana huluhulu - kahi ʻano maʻi ʻaʻai koko
• ʻO ka maʻi Hodgkin - ka maʻi ʻaʻai o ka aʻa lymph
• ʻO ka maʻi ʻōpiopio ʻōpio - ʻōpio e hoʻopili i nā keiki
• Myeloma maha - kahi ʻano maʻi ʻaʻai koko
• Reiter Syndrome - kahi hui o nā kumu i kumu i ka pehu a me ka mumū o nā hono, nā maka, a me nā ʻōnaehana mimi a me nā genital)
• Rheumatoid arthritis
• ʻO systemic lupus erythematosus - kahi maʻi autoimmune
• Maʻi puʻu

Nā ʻōuli o ka amyloidosis ʻōnaehana lua e kaukaʻi ʻia i nā aʻa o ke kino e hoʻopili ʻia e nā waihona protein. Hoʻopōʻino kēia mau waihona i nāʻaʻaʻa maʻamau. Hiki i kēia ke alakaʻi i nā hōʻailona a i ʻole nā ​​hōʻailona o kēia maʻi, me:

• Kahe i ka ʻili
• Ka luhi
• Paʻi kuʻi ʻole
• Numbness o nā lima a me nā wāwae
• Rash
• Pokole o ka hanu
• Hoʻopau i nā pilikia
• Pākuʻi nā lima a i ʻole nā ​​wāwae
• Alelo pehu
• Paʻa lima nāwaliwali
• Kaumaha emi

E hana ka mea mālama ola i kahi hoʻokolokolo kino a nīnau e pili ana i kāu mau hōʻailona.

ʻO nā hoʻāʻo e hana ʻia ana paha:

• Abdominal ultrasound (hōʻike paha i ke ake a pehu paha)
• ʻO Biopsy a i ʻole ʻiʻini o ka momona ma lalo pono o ka ʻili (momona subcutaneile)
• ʻO Biopsy o ka pololei
• ʻO Biopsy o ka ʻili
• Biopsy o ka iwi iwi
• Nā ho'āʻo koko, e pili ana i ka creatinine a me BUN
• ʻEchocardiogram
• Electrocardiogram (ECG)
• ʻO ka wikiwiki conduction nerve
• Urinalysis

Pono e mālama ʻia ke ʻano e hoʻoulu nei i ka amyloidosis. I kekahi mau hihia, kuhikuhi ʻia ka lāʻau colchicine a i ʻole kahi lāʻau biologic (lāʻau lapaʻau e mālama ai i ka ʻōnaehana pale.

Ma ke ʻano o ka hilinaʻi ʻana o ke kanaka i ka hopena o nā meaola e hoʻopili ai. Pili pū kekahi, inā paha ʻo ka maʻi ke kumu e hiki ai ke kāohi ʻia. Inā pili ka maʻi i ka puʻuwai a me nā puʻupaʻa, hiki i ka hopena o ka hopena a me ka make.

ʻO nā pilikia olakino i hopena ʻia mai ka amyloidosis ʻōnaehana lua pū kekahi:

• Hoka endocrine
• Hewa puʻuwai
• Hewa ʻole nā ​​hakuʻala
• Hoʻoikaika hanu ʻole

Kāhea i kāu mea hāʻawi inā loaʻa iā ʻoe nā ʻōuli o kēia ʻano. ʻO nā mea aʻe nā hōʻailona koʻikoʻi e pono e mālama koke i ka lāʻau.

• Kahena
• Paʻi kuʻi ʻole
• Pōpō
• Pokole o ka hanu
• ʻŌhū
• Paʻa nāwaliwali

Inā loaʻa ʻoe i kahi maʻi e ʻike ʻia e hoʻonui i kou makaʻu no kēia ʻano, e mālama pono iā ʻoe. Hiki paha i kēia ke kōkua i ka pale ʻana i ka amyloidosis.

ʻO Amyloidosis - ʻōnaehana kekona; AA amyloidosis

• ʻO Amyloidosis o nā manamana lima
• ʻO Amyloidosis o ka maka
• Nā Antibodies

ʻO Gertz MA. ʻO Amyloidosis. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 25th hua. Piladelapia, PA: Elsevier Saunders; 2016: chap 188.

Papa R, Lachmann HJ. Kahikina, AA, Amyloidosis. ʻO Rheum Dis Clin North Am. 2018; 44 (4): 585-603. PMID: 30274625 www.ncbi.nlm.nih.gov/pubmed/30274625.