Factor XII (Hageman factor) nele

ʻO ka hemahema Factor XII kahi maʻi hoʻoilina e pili ana i kahi protein (factor XII) i pili i ka hoʻopili ʻia ʻana o ke koko.

Ke kahe nei ʻoe i ke kahe, hana ʻia kahi hopena o nā hopena i loko o ke kino e kōkua ai i ke kōkō ʻana o ke koko. Kapa ʻia kēia hana ke cascade coagulation. Pili ia i nā proteins kūikawā i kapa ʻia ka coagulation a i ʻole nā ​​kumu hoʻohui. Loaʻa paha iā ʻoe kahi manawa kiʻekiʻe o ke kahe ʻana o ke kahe inā e nalowale ana hoʻokahi a ʻoi paha o kēia mau kumu a hana ʻole paha e like me ka mea e pono ai.

ʻO Factor XII kekahi ʻano like. ʻO ka nele o kēia kumu ʻaʻole ʻoe e kahe koko ʻole. Akā, ʻoi aku ka lōʻihi o ke koko ma mua o ka maʻamau e hoʻopili i kahi pahu hoʻāʻo.

ʻO ka hemahema ʻo Factor XII kahi maʻi hoʻoilina maʻamau.

ʻAʻohe hōʻailona maʻamau.

ʻIke pinepine ʻia ka hemahema o XNUMX Factor i ka wā e hana ʻia nā hoʻokuʻi ʻana no ka kānana maʻamau.

E komo pū paha nā hoʻāʻo:

• ʻIke XII mea e ana i ka hana o ka helu XII
• ʻO ka manawa thromboplastin hapa (PTT) e nānā ai i ka lōʻihi o ke kō ʻana o ke koko
• Hoʻohui hoʻohuihui, kahi hōʻike PTT kūikawā e hōʻoia i ka hemahema XII mea

ʻAʻole pono ka lapaʻau ʻana.

Hiki i kēia mau kumuwaiwai ke hāʻawi i ka ʻike hou aku e pili ana i ka hemahema XII mea:

• National Hemophilia Foundation - www.hemophilia.org/Bleeding-Disorders/Types-of-Bleeding-Disorders/Other-Factor-Deficiencies/Factor-XII
• National Organization for Rare Disorder - rarediseases.org/rare-diseases/factor-xii-deficiency
• NIH Genetic and Rare Diseases Information Center - rarediseases.info.nih.gov/diseases/6558/factor-xii-deficiency

Manaʻo ʻia he maikaʻi ka hopena me ka ʻole o ka lāʻau.

ʻAʻohe maʻamau i nā pilikia.

ʻIke pinepine ka mea mālama ola i kēia ʻano ke holo ʻana i nā hoʻokolohua lab.

He maʻi hoʻoilina kēia. ʻAʻohe ala i ʻike ʻia e pale aku ai.

Hemahema F12; Hageman factor deficiant; ʻAno Hageman; Ka nele o HAF

• Huʻi koko

ʻO Gailani D, Wheeler AP, Neff AT. Nā hemahema coagulation ololi. I: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Nā Kumumanaʻo a me ka Hoʻomeheu. ʻEpekema 7 Piladelapia, PA: Elsevier; 2018: chap 137.

Halelu JE. Hemostasis a me ka coagulation koko. I: Hall JE, hoʻoponopono. ʻO Guyton a me Hall Textbook of Medical Physiology. 13th ed. Piladelapia, PA: Elsevier; 2016: chap 37.

ʻO Ragni MV. Nā maʻi hemorrhagic: deficiencies factor coagulation. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 25th hua. Piladelapia, PA: Elsevier Saunders; 2016: chap 174.