ʻO Glucagonoma

ʻO Glucagonoma kahi tumo kakaikahi loa o nā huna pae mokupuni o ka pancreas, kahi e alakaʻi ai i kahi ʻoi aku o ka hormone glucagon i loko o ke koko.

ʻO Glucagonoma ka maʻi maʻamau (malignant). Mālama ka maʻi ʻaʻai a hele a māhuahua.

Hoʻopili kēia maʻi ʻaʻai i nā huna wai o ka pancreas. A ʻo kahi hopena, hoʻopuka nui nā hunaola mokupuni i ka nui o ka hormone glucagon.

ʻAʻole ʻike ʻia ke kumu. He mea nui nā kumu genetic i kekahi mau hihia. ʻO kahi moʻolelo ʻohana o ka maʻi maʻi he endocrine neoplasia ʻano I (MEN I) kahi mea pilikia.

Hiki i nā ʻōuli o ka glucagonoma ke hoʻopili i kekahi o kēia mau mea:

• ʻO ke ahonui Glucose (pilikia ka kino i ka haki ʻana i nā kō)
• ʻO ke kō kiʻekiʻe (hyperglycemia)
• Pohā
• Make wai loa (ma muli o ke kō i ke kō.)
• Pinepine urination (ma muli o ke kiʻekiʻe kō kō)
• Hoʻonui i ka makemake
• Hoʻā ʻia ka waha a me ke elelo
• ʻO ka urination pō (nocturnal)
• ʻ rhū o ka ʻili ma ka maka, ʻōpū, kuʻupuʻu, a i ʻole nā ​​wāwae e hele mai a hele, a neʻe a puni
• Kaumaha emi

I ka hapanui o nā hihia, ua pālahalaha ka maʻi ʻaʻai i ke ake ke ʻike ʻia.

E hana ka mea mālama ola i kahi hoʻokolohua kino a nīnau e pili ana i kāu mōʻaukala a me nā ʻōuli.

ʻO nā hoʻāʻo e hana ʻia ana paha:

• CT scan o ka ʻōpū
• ʻO ka pae Glucagon i ke koko
• ʻO ka pae Glucose i ke koko

Paipai ʻia ke ʻoki e wehe ai i ka tumo. ʻAʻole pane ka tumo i ka chemotherapy.

Hiki iā ʻoe ke hoʻomāmā i ke koʻikoʻi o ka maʻi ma ke komo ʻana i kahi hui kākoʻo maʻi ʻaʻai. ʻO ke kaʻana ʻana me nā poʻe ʻē aʻe i loaʻa nā ʻike a me nā pilikia maʻamau e hiki ke kōkua iā ʻoe e noʻonoʻo ʻole.

Ma kahi o 60% o kēia mau tumors he maʻi ʻaʻai. He mea mau kēia laha ʻana o kēia maʻi ʻaʻai i ke ake. Ma kahi o 20% o ka poʻe e hiki ke hoʻōla ʻia me ke kahakaha.

Inā ʻo ka tumo wale i ka pancreas a me ke kīʻaha e hemo ai ke kūleʻa, loaʻa i nā kānaka kahi ola ola 5-makahiki o 85%.

Hiki ke pālahalaha ka maʻi ʻaʻai i ke ake. Hiki i ke kiʻekiʻe o ke kō ke kō ke kumu i nā pilikia me ka metabolism a me ka hōʻino ʻana o ka ʻaʻa.

Kāhea i kāu mea hāʻawi inā ʻike ʻoe i nā ʻōuli o glucagonoma.

MEN I - glucagonoma

• Nānā Endocrine

Pūnaewele ʻo National Cancer Institute. ʻO nā tumere neuroendocrine Pancreatic (tumors cell tumors) lapaʻau (PDQ) - mana ʻoihana olakino. www.kanaka.gov/types/pancreatic/hp/pnet-treatment-pdq. Hoʻohou i Pepeluali 8, 2018. Loaʻa iā Nowemapa 12, 2018.

ʻO Schneider DF, Mazeh H, Lubner SJ, Jaume JC, Chen H. Cancer o ka ʻōnaehana endocrine. I: Niederhuber JE, Armitage JO, Doroshow JH, Kastan MB, Tepper JE, eds. ʻO Oncology Clinical ʻo Abboff. 5th lā. Piladelapia, PA: Elsevier Saunders; 2014: chap 71.

ʻO Vella A. Gastrointestinal hormones a me nā ʻōpū endocrine ʻōpū. I: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. ʻO Williams Textbook of Endocrinology. 13th ed. Piladelapia, PA: Elsevier; 2016: chap 38.