ʻO MS-PP Holomua (PPMS): Nā Hōʻailona a me nā Diagnosis

Anter

• Pehea ka PPMS ʻokoʻa mai nā ʻano MS?
• He aha ke kumu o PPMS?
• He aha nā hōʻailona o PPMS?
• Musical spasticity
• Ka luhi
• Numbness / tingling
• Nā pilikia me ka hihiʻo
• Nā pilikia me ka ʻike
• Puʻupuʻu
• Nā pilikia o ka ʻōpū a me ka ʻōpū
• Kaumaha
• Pehea e ʻike ʻia ai ka PPMS?
• Nā koho lapaʻau
• Outlook

He aha ka PPMS?

ʻO ka sclerosis maha (MS) ka maʻi maʻamau o ke kikowaena pūnaewele. Hoʻokumu ʻia ia e ka pane pale ʻole e luku i ka uhi myelin, a i ʻole ke uhi ʻana i nā ʻalolo.

ʻO ka sclerosis maha mua loa (PPMS) kekahi o nā ʻano ʻehā o MS. ʻO nā ʻano ʻekolu ʻē aʻe o MS:

• maʻi maʻi kaʻawale (CIS)
• relapsing remitting (RRMS)
• holomua lua (SPMS)

ʻO PPMS kekahi o nā ʻano maʻamau liʻiliʻi, e hoʻopili ana ma kahi o 10 pakeneka o nā poʻe āpau i ʻike ʻia me MS.

Pehea ka PPMS ʻokoʻa mai nā ʻano MS?

ʻO ka hapa nui o ka poʻe i hoʻopilikia ʻia e MS he hōʻeha koʻikoʻi me nā ʻōuli, i kapa ʻia ʻo relapses, a me nā wā o nā mahina a i ʻole mau makahiki me ka liʻiliʻi o nā ʻōuli, i kapa ʻia nā kala.

ʻOkoʻa ka PPMS. Holomua ka maʻi i ka manawa e hoʻomaka ai nā ʻōuli, no laila ka inoa holomua. Aia kekahi mau manawa o ka holomua hana a laila nā wā o ka holomua ʻole o nā ʻōuli a me ke kīnā.

ʻO kekahi ʻokoʻa ma waena o PPMS a me nā palapala i hoʻi hou ʻoiai ʻoiai e kū ka holomua hana no kekahi manawa, ʻaʻole hoʻoholo nā ʻōuli. I nā palapala hoʻi hou ʻana, hoʻomaikaʻi a hoʻi paha nā hōʻailona ma kahi o lākou ma mua o ka hoʻi hou ʻana.

ʻO kahi ʻokoʻa ʻokoʻa ka nui ʻole o ka mumū ma PPMS i hoʻohālikelike ʻia i nā ʻano relapsing. Ma muli o kēia, ʻaʻole hana ka nui o nā lāʻau e hana no ka hoʻi hou ʻana i nā pepa no PPMS a i ʻole SPMS. Hiki ke hoʻonui i ka holomua o nā hōʻailona ma kahi o kekahi mau mahina a i ʻole mau makahiki.

Hoʻomaopopo pinepine ʻia ʻo PPMS i nā poʻe i 40 a 50 paha mau makahiki. ʻO RRMS, ma ka ʻaoʻao ʻē aʻe, maʻa mau i nā poʻe i ko lākou 20 a 30 paha. Hoʻopili like ʻo PPMS i nā kāne ʻelua i ka like, ʻoiai ʻo RRMS e hoʻopili i ʻelua a ʻekolu mau manawa i ka nui o nā wahine e like me nā kāne.

He aha ke kumu o PPMS?

Hoʻokumu ʻia ʻo PPMS e nā hōʻino nerve lohi e hoʻōki i nā aʻalolo mai ka hoʻouna ʻana i nā hōʻailona i kekahi i kekahi. Pili nā ʻano ʻehā o MS i ka hōʻino ʻana i ka uhi pale (myelin) o ka ʻōnaehana ʻōnaehana waena, i kapa ʻia he demyelination, a me ka hōʻino ʻana i ke aʻalolo.

He aha nā hōʻailona o PPMS?

ʻO nā hōʻailona PPMS e like me nā hōʻailona SPMS. ʻOiaʻiʻo, he ʻokoʻa ka mea a kekahi kanaka e ʻike ai mai kekahi ʻē aʻe.

Pākuʻi ʻia paha nā ʻōuli o PPMS i kēia mau mea:

Musical spasticity

ʻO ka hoʻohaʻahaʻa mau ʻana o kekahi mau mākala ke kumu o ka paʻakikī a me ka paʻa, i hiki ke hoʻololi i ka neʻe. Hiki i kēia ke hana i mea paʻakikī e hele wāwae, hoʻohana i nā ʻanuʻu, a hoʻohuli i kāu pae hana holoʻokoʻa.

Ka luhi

Ma kahi o 80 pākēneka o ka poʻe me PPMS ʻike i ka luhi. Hiki i kēia ke hoʻololi nui i ke ola o kēlā me kēia lā a paʻakikī i ka hana a hoʻopau i nā hana maʻamau. ʻO ka poʻe i ʻike ʻia me PPMS e luhi paha lākou iā lākou iho mai nā hana maʻalahi. ʻO kahi laʻana, hiki i ka hana o ke kuke ʻana i ka ʻaina awakea ke hoʻopau iā lākou a koi iā lākou e hiamoe.

Numbness / tingling

ʻO kekahi hōʻailona mua o ka PPMS ka helu a i ʻole ka ʻūlū ʻana i nā ʻāpana o ke kino, e like me kou alo, lima, a me kou mau wāwae. Hiki ke hoʻopaʻa ʻia kēia i hoʻokahi wahi o kou kino, a i ʻole huakaʻi i nā ʻāpana ʻē aʻe.

Nā pilikia me ka hihiʻo

Hiki i kēia ke hoʻopili i ka hihiʻo lua, ʻike maka ʻole, hiki ʻole ke ʻike i nā kala a me nā ʻokoʻa, a me ka ʻeha ke neʻe i kou mau maka.

Nā pilikia me ka ʻike

ʻOiai pili pinepine ʻo PPMS i ka neʻe, e ʻike paha kekahi mau kānaka i ka hāʻule o ka naʻau. Hiki i kēia ke hōʻino nui i ka hoʻomanaʻo ʻana a me ka hana ʻana i ka ʻike, ka hoʻoponopono ʻana i nā pilikia, ke kia ʻana, a me ke aʻo ʻana i kekahi mea hou.

Puʻupuʻu

ʻO ka poʻe me PPMS paha he mau ʻāpana o ka dizziness a me ka lightheadedness. Hiki paha i nā poʻe ʻē aʻe ke ʻike i ka vertigo, kahi manaʻo e wili nei lākou a nalowale ana i kā lākou kaulike.

Nā pilikia o ka ʻōpū a me ka ʻōpū

Hiki i nā pilikia o ka puhū a me ka ʻōpū mai ke incontinence, a hiki i ka pono mau e hele, i ka constipation. Hiki i kēia ke alakaʻi i nā pilikia moekolohe, e like me ka hōʻemi ʻana i ka hoʻokele wahine, ka paʻakikī e mālama i ke kūkulu ʻana, a me ka liʻiliʻi o ka naʻau i nā genital.

Kaumaha

Ma kahi o ka hapalua o nā poʻe āpau me MS e kū mua ana i hoʻokahi kaukana depressive. ʻOiai he mea maʻamau ka huhū a huhū paha e pili ana i ka nui o ke kīnā ʻole, hele mau kēia mau ʻano me ka manawa. ʻO ke kaumaha kaumaha, ma ka ʻaoʻao ʻē aʻe, ʻaʻole e emi a koi aku i ka lāʻau.

Pehea e ʻike ʻia ai ka PPMS?

He mau ʻōuli like ko PPMS i nā ʻano MS ʻē aʻe, a me nā maʻi ʻōnaehana ʻē aʻe. A ʻo kahi hopena, he ʻekolu paha mau makahiki ka lōʻihi o ka loaʻa ʻana o kahi hōʻoia PPMS i hōʻoia ʻia ma mua o kahi hōʻike RRMS.

No ka loaʻa ʻana o kahi hōʻoia PPMS i hōʻoia ʻia, pono ʻoe:

• i hoʻokahi makahiki o ka holomua ʻana o ka hana neurologic
• e hālāwai me ʻelua o nā pae i lalo:
  • kahi liona lolo e maʻa mau iā MS
  • ʻelua a ʻoi aku paha nā leheleona like i kāu kaula ʻōiwi
  • ke alo o nā protein i kapa ʻia immunoglobulins

E alakaʻi paha kāu kauka i kahi hoʻokolohua mōʻaukala olakino a nīnau iā ʻoe e pili ana i nā hanana neurologic ma mua. Noi paha lākou i nā ʻohana e noho pū, no ka mea hiki iā lākou ke hāʻawi i kā lākou ʻike me nā ʻōuli i hala. E hana paha kāu kauka i kahi hoʻokolohua kino piha, kikoʻī i ka nānā ʻana i kou ʻalolo a me nā mākala.

E kauoha kāu kauka i kahi scan MRI e nānā i nā liona i ka lolo a me ka iwi kuamoʻo. Hiki paha iā lākou ke kauoha i kahi hoʻokolohua e hoʻāla ʻia (EP) e hōʻoia no ka hana uila i ka lolo. ʻO ka mea hope loa, e hana kāu kauka i ka pihi ʻōiwi e nānā i nā hōʻailona o MS i loko o ka wai spinal.

Nā koho lapaʻau

ʻAʻohe mea ola no PPMS. Hoʻokahi lāʻau lapaʻau, ʻocrelizumab (Ocrevus), ʻae ʻia no PPMS a me nā ʻano relapsing o MS. Hoʻohana pinepine ʻia nā Immunosuppressants i nā ʻano relapsing, akā naʻe, no ka mea, hoʻemi lākou i ka pehu. ʻAʻole nui ka mumū o ka PPMS, no laila ʻaʻole e koi ʻia nā pale pale pale e like me ke kūpono. Ke hoʻomau nei ka noiʻi ʻana e pili ana i nā mālama pono ʻana.

Outlook

ʻOiai ʻaʻohe mea ola no PPMS, ʻaʻole pono e haʻalele ka poʻe i ʻike ʻia me PPMS i ka manaʻolana. Me ke kōkua o nā kauka, nā ʻoihana hoʻomaʻamaʻa kino, nā pathologist ʻōlelo, a me nā loea i ke olakino noʻonoʻo, aia kekahi mau ala e mālama ai i ka maʻi. Hiki i kēia mau mea ke hoʻopili i nā lāʻau e kōkua i ka hōʻoluʻolu i nā ʻōuli, e like me nā relant muscle no ka spasms muscle, a me ka papaʻai olakino, hoʻoikaika kino, a me kahi papa moe kūpono.