Nā lāʻau Coronavirus (COVID-19): ʻae ʻia a ma lalo o ke aʻo ʻana
Anter
- Nā lāʻau i ʻae ʻia no coronavirus
- Ke aʻo ʻia nei nā hoʻoponopono
- 1. ʻO Ivermectin
- 2. Plitidepsin
- 3. Remdesivir
- 4. Dexamethasone
- 5. ʻO Hydroxychloroquine a me chloroquine
- 6. ʻO Colchisin
- 7. Mefloquine
- 8. ʻO Tocilizumab
- 9. Palapala hoʻohalahala plasma
- 10. ʻO Avifavir
- 11. ʻO Baricitinib
- 12. EXO-CD24
- Nā koho hoʻoponopono kūlohelohe no ka coronavirus
I kēia manawa, ʻaʻohe lāʻau i ʻike ʻia hiki ke hoʻopau i ka coronavirus hou mai ke kino a, no kēia kumu, i ka hapanui o nā hihia, hana ʻia ka lapaʻau me kekahi mau ana a me nā lāʻau i hiki ke hoʻomaha i nā ʻōuli o COVID-19.
ʻO nā hihia māmā, me nā ʻōuli e like me ka flu maʻamau, hiki ke mālama ʻia i ka home me ka hoʻomaha, hydration a me ka hoʻohana ʻana i nā lāʻau fiva a me nā mea ʻeha. ʻO nā hihia ʻoi loa, kahi e ʻike ʻia ai nā ʻōuli ikaika a me nā pilikia e like me ka pulumonia, pono e mālama ʻia i ke komo ʻana i ka haukapila, pinepine i nā Intensive Care Units (ICU), e hōʻoia, keu hoʻi, ka lawena kūpono o ka oxygen a me ka nānā ʻana o hōʻailona koʻikoʻi.
E ʻike i nā kikoʻī e pili ana i ka lapaʻau ʻana no COVID-19.
Ma waho aʻe o nā lāʻau, ke aʻo ʻia nei kekahi mau lāʻau lapaʻau kūʻē iā COVID-19. Hoʻohiki kēia mau lāʻau lapaʻau e pale aku i ka maʻi o COVID-19, akā e like me ka hoʻoliʻiliʻi o ka ikaika o nā hōʻailona ke hiki mai ka maʻi. Maikaʻi e hoʻomaopopo ai i nā lāʻau āpau e kūʻē iā COVID-19, pehea e hana ai a hiki i nā hopena ʻaoʻao.
Nā lāʻau i ʻae ʻia no coronavirus
ʻO nā lāʻau i ʻae ʻia no ka mālama ʻana i ka coronavirus, e Anvisa a me ka Ministry of Health, ʻo ia nā mea hiki ke hoʻomaha i nā ʻōuli o ka maʻi, e like me:
- Nā Antipyretics: e hoʻohaʻahaʻa i ka mahana a hakakā i ka wela;
- Nā mea hōʻeha ʻeha: e hōʻoluʻolu i ka ʻehaʻeha ma ke kino holoʻokoʻa;
- Nā Antibiotics: e mālama i nā maʻi bacteria i hiki ke kū aʻe me COVID-19.
E hoʻohana wale ʻia kēia mau mea lapaʻau ma lalo o ke alakaʻi a ke kauka a, ʻoiai ua ʻae ʻia no ka mālama ʻana i ka coronavirus hou, ʻaʻole hiki iā lākou ke hoʻopau i ka maʻi mai ke kino, akā hoʻohana wale ʻia ia e hōʻoluʻolu i nā hōʻailona a hoʻomaikaʻi i ka ʻoluʻolu o ke kanaka maʻi.
Ke aʻo ʻia nei nā hoʻoponopono
Ma waho aʻe o nā lāʻau e kōkua i ka hōʻoluʻolu i nā ʻōuli, ke hoʻomohala nei kekahi mau ʻāina i nā noiʻi ʻana i nā holoholona keʻena hoʻokolohua a me nā mea maʻi maʻi e hoʻāʻo e ʻike i kahi lāʻau e hiki ke hoʻopau i ka maʻi mai ke kino.
ʻAʻole pono e hoʻohana ʻia nā lāʻau i aʻo ʻia me ke alakaʻi ʻole a ke kauka, a i ʻole he kumu e pale aku ai i ka maʻi, no ka mea he kumu ia no nā hopena ʻē aʻe a hoʻoweliweli hoʻi i ke ola.
ʻO ka papa inoa aʻe o nā lāʻau nui e hoʻopaʻa ʻia no ka coronavirus hou.
1. ʻO Ivermectin
ʻO Ivermectin kahi vermifuge i hōʻike ʻia no ka mālama ʻana i nā infestation parasite, ka mea e hoʻopilikia ai i nā pilikia e like me onchocerciasis, elephantiasis, pediculosis (lice), ascariasis (roundworms), scabies a i ʻole strongyloidiasis ʻōpū a ʻo ia hoʻi, nā hopena maikaʻi loa i hōʻike ʻia i ka hoʻopau ʻia ʻana o ka coronavirus hou, i loko o vitro.
Ua mālama ʻia kahi noiʻi ma Australia, ua hoʻāʻo ʻo ivermectin i loko o ke keʻena hoʻokolohua, i nā moʻomeheu paʻa i loko o vitro, a ua ʻike ʻia ua hiki i kēia mea ke hoʻopau i ka maʻi SARS-CoV-2 i loko o 48 mau hola [7]. Eia nō naʻe, pono i nā hoʻokolohua hoʻokolohua i nā kānaka e hōʻoia i kona pono i loko o vivo, a me ka mahele lāʻau lapaʻau a me ka palekana o ka lāʻau, i manaʻo ʻia e kū i kahi wā ma waena o 6 a 9 mau mahina.
Eia hou, ua hōʻike ʻia kahi noiʻi ʻē aʻe i ka hoʻohana ʻana o ivermectin e nā mea maʻi i ʻike ʻia me COVID-19 e hōʻike ana i ka hoʻemi ʻia ʻana o nā pilikia a me ka holo ʻana o ka maʻi, e hōʻike ana i hiki ivermectin ke hoʻomaikaʻi i ka wānana o ka maʻi. [33]. I ka manawa like, ua hōʻike ʻia kahi noiʻi i hana ʻia ma Bangladesh i ka hoʻohana a me ka ivermectin (12 mg) no 5 mau lā he maikaʻi a palekana hoʻi i ka mālama ʻana iā COVID-19 [34].
I Nowemapa 2020 [35] ke kuhiakau o nā kānaka noiʻi India e hiki iververectin ke hoʻopilikia i ka lawe ʻana o ka maʻi i ka nukelea o nā hunaola, e pale ana i ka hoʻomohala ʻia ʻana o ka maʻi, i paʻi ʻia i loko o ka puke pai ʻepekema, akā hiki wale nō kēia hopena me nā kaona kiʻekiʻe o ivermectin, a he mea ʻino paha ia i ke kino kanaka.
Ua hoʻokuʻu ʻia kahi noi ʻē aʻe i Kekemapa 2020 [36] ua hōʻike ʻia nō hoʻi ka hoʻohana ʻana o nā nanoparticle i loaʻa ivermectin hiki ke hoʻēmi i ka ʻōlelo o nā cellular 'ACE2 receptors, e hoʻēmi nei i ka likelika o ka maʻi e hoʻopaʻa i kēia mau receptor a hoʻokumu i ka maʻi. Eia nō naʻe, ua hana ʻia kēia aʻo ʻana ma ka vitro wale nō, a ʻaʻole hiki ke ʻōlelo ʻia e like ka hopena ma vivo. Hoʻohui, no ka mea he ʻano therapeutic hou kēia, pono nā noiʻi ʻona.
I loko nō o kēia mau hopena, pono ʻia nā noiʻi hou e hōʻike i ka maikaʻi o ivermectin i ka mālama ʻana o COVID-19, a me ka hopena i ka pale ʻana i ka maʻi. E ʻike hou aʻe e pili ana i ka hoʻohana ʻana o ivermectin e kūʻē iā COVID-19.
Lulai 2, 2020 Hoʻohou:
Ua hoʻokuʻu ʻia e ka São Paulo Regional Pharmacy Council (CRF-SP) kahi palapala ʻenehana [20] i loko o ia mea e hōʻike nei i ka lāʻau ivermectin hōʻike i ka antiviral hana i loko o kekahi mau in-vitro haʻawina, akā e pono ana i nā hoʻokolokolo hou e noʻonoʻo ai hiki ke hoʻohana palekana ʻia ivermectin i nā kānaka e kūʻē iā COVID-19.
No laila, aʻoaʻo ʻo ia e hana wale ʻia ke kūʻai ʻana o ivermectin me ka hōʻike ʻana i kahi lāʻau lapaʻau a ma loko o nā kaukū a me nā manawa i aʻo ʻia e ke kauka.
Iulai 10, 2020 Hoʻohou:
Wahi a kahi leka wehewehe i hoʻokuʻu ʻia e ANVISA [22], ʻaʻohe noiʻi hope loa e hōʻoia i ka hoʻohana ʻana o ivermectin no ka mālama ʻana o COVID-19, a ʻo ka hoʻohana ʻana i ka lāʻau e mālama ai i ka maʻi me ka coronavirus hou ke kuleana o ke kauka nāna e alakaʻi nei i ka mālama.
Hoʻohui ʻia, nā hopena mua i hoʻokuʻu ʻia e kahi noi na USP's Institute of Biomedical Science (ICB) [23], e hōʻike i ivermectin, ʻoiai hiki ke hoʻopau i ka maʻi mai nā hunaola i loaʻa i loko o ke keʻena hoʻokolohua, ke kumu hoʻi o ka make ʻana o kēia mau hunaola, kahi e hōʻike ai ʻaʻole paha kēia ka lāʻau lapaʻau ka hopena ʻoi aku ka maikaʻi.
Hoʻohou i Kekemapa 9, 2020:
I loko o kahi palapala i hoʻokuʻu ʻia e ka Hui Pūʻali Infectious Brazil (SBI) [37] ua hōʻike ʻia ʻaʻohe ʻōlelo aʻoaʻo no ka lāʻau lapaʻau mua a me / a i ʻole prophylactic lapaʻau no COVID-19 me nā lāʻau, e like me ivermectin, ʻoiai ʻo nā noiʻi maʻi maʻi i lawe ʻia i kēia manawa ʻaʻole hōʻike i nā pono a, e pili ana i ka lāʻau, hoʻohana ʻia, e hoʻopili ʻia me nā hopena i hiki ke loaʻa i nā hopena no ke olakino olakino o ke kanaka.
Hoʻohou i Pepeluali 4, 2021:
ʻO Merck, ʻo ia ka ʻoihana lāʻau lapaʻau i kuleana no ka hana ʻana o ka lāʻau Ivermectin, i hōʻike ʻia i loko o nā noiʻi i hoʻomohala ʻia ʻaʻole ia i ʻike i nā hōʻike ʻepekema e hōʻike ana i ka hiki ke ola o kēia lāʻau e kūʻē iā COVID-19, ʻaʻole hoʻi i hōʻike i kahi hopena i nā maʻi. ua ʻike ʻia me ka maʻi.
2. Plitidepsin
ʻO Plitidepsin kahi lāʻau anti-tumor i hana ʻia e kahi hale hana Sepania i hōʻike ʻia no ka mālama ʻana i kekahi mau hihia o ka myeloma he nui, akā he hopena anti-viral ikaika ia e kūʻē i ka coronavirus hou.
Wahi a kahi noiʻi i hana ʻia ma United States [39], hiki i ka plitidepsin ke hōʻemi i ka viral viral o ka coronavirus a i ka 99% i loko o nā akemāmā o nā ʻiole laboratory i hoʻopili ʻia me COVID-19. Hōʻoia nā kānaka noiʻi i ka kūleʻa o ka lāʻau i kona hiki ke ālai i kahi protein i loko o nā hunaola e pono ai no ka maʻi e hoʻonui a hoʻolaha i ke kino.
ʻO kēia mau hopena, me ka hoʻohana ʻia ʻana o ka lāʻau i loko o ke kanaka no ka mālama ʻana i nā myeloma he nui, e ʻōlelo ana he palekana paha ka lāʻau e hoʻāʻo ʻia i nā mea maʻi i loaʻa i ka maʻi COVID-19. No laila, he mea pono e kali no ka hopena o kēia mau hoʻokolohua hoʻokolohua e hoʻomaopopo ai i ka hana a me ka hiki ke ʻino o ka lāʻau.
3. Remdesivir
ʻO kēia kahi lāʻau laulā ākea ākea ākea i hoʻomohala ʻia e mālama i ka maʻi Ebola, akā ʻaʻole i hōʻike ʻia nā hopena maikaʻi e like me nā mea ʻē aʻe. Eia nō naʻe, ma muli o kāna ākea hana e kūʻē i nā virus, ke aʻo ʻia nei e hoʻomaopopo inā hiki ke hōʻike i nā hopena maikaʻi aʻe i ka hoʻopau ʻana i ka coronavirus hou.
ʻO nā haʻawina mua i hana ʻia i ka hale hana me kēia lāʻau, ma ʻAmelika Hui Pū ʻIa [1] [2], e like me Kina [3], hōʻike i nā hopena hoʻohiki, no ka mea hiki i ka mea ke pale i ka hana hou a me ka hoʻonui ʻana o ka coronavirus hou, a me nā mea ʻino ʻē aʻe o ka ʻohana coronavirus.
Eia nō naʻe, ma mua o ka hiki ke ʻōlelo ʻia ma ke ʻano he ʻano lapaʻau, pono e hana i kēia lāʻau i kekahi mau noiʻi me nā kānaka, i mea e maopopo ai i kona pono maoli a me ka palekana. No laila, aia, i kēia manawa, e pili ana i 6 mau noiʻi e lawe ʻia nei me nā helu he nui o nā maʻi i hoʻopili ʻia me COVID-19, ma ʻAmelika Hui Pū ʻIa, ma ʻEulopa a me Iapana, akā e hoʻokuʻu wale ʻia nā hopena ma ʻApelila , no kēia manawa, ʻaʻohe hōʻike e hiki ai iā Remdesivir ke hoʻohana me ka palekana e hoʻopau i ka coronavirus hou i nā kānaka.
ʻApelila 29, 2020 Hoʻohou:
Wahi a kahi hoʻokolokolo a Galaad Science [8], maʻAmelika Hui Pū ʻIa, ʻo ka hoʻohana ʻana o Remdesivir i nā mea maʻi me COVID-19 me he mea lā ke hōʻike nei i nā hopena like i kahi manawa mālama o 5 a 10 mau lā, a ma nā hihia ʻelua ua hoʻokuʻu ʻia nā mea maʻi mai ka haukapila ma kahi o 14 mau lā a me ka ʻaoʻao hanana. haʻahaʻa nā hopena. ʻAʻole hōʻike kēia noiʻi i ke kiʻekiʻe o ka pono o ka lāʻau e hoʻopau i ka coronavirus hou a, no laila, ke hana ʻia nei nā noiʻi ʻē aʻe.
Mei 16, 2020 Hoʻohou:
ʻO kahi noiʻi ma Kina ma nā maʻi 237 me nā hopena koʻikoʻi o ka maʻi COVID-19 [15] ua hōʻike ʻo nā mea maʻi i mālama ʻia me kēia lāʻau i hōʻike i kahi ola wikiwiki i hoʻohālikelike ʻia i nā mea maʻi kaohi, me ka awelika o 10 mau lā i hoʻohālikelike ʻia me nā lā 14 i hōʻike ʻia e ka hui i mālama ʻia me kahi placebo.
Hoʻohou i Mei 22, 2020:
ʻO ka hōʻike mua o kahi hoʻokolokolo hou i hana ʻia ma United States me Remdesivir [16] kuhikuhi pū ʻia ka hoʻohana ʻana o kēia lāʻau i mea e hōʻemi ai i ka manawa hoʻōla i nā mākua i hōʻola ʻia, a me ka hoʻoliʻiliʻi o ka maʻi o ka maʻi hanu haʻahaʻa.
Hoʻohou i Iulai 26, 2020:
Wahi a kahi noiʻi a ke Kula Nui o ke Kula Nui o ke Kula Nui ʻo Boston [26], remdesivir hoʻemi i ka manawa lapaʻau i nā mea maʻi i ʻae ʻia i ka ICU.
Nowemapa 5, 2020 Hoʻohou:
ʻO ka hōʻike hope loa o ke aʻo ʻana i hana ʻia ma ʻAmelika Hui Pū ʻIa me Remdesivir hōʻike i ka hoʻohana ʻana o kēia lāʻau lapaʻau, ʻoiaʻiʻo, hoʻemi i ka manawa awelika o ka manawa hoʻōla i nā mākua i hōʻola ʻia, mai 15 a 10 mau lā. [31].
Nowemapa 19, 2020 Hoʻohou:
Ua hoʻopuka ka FDA ma ʻAmelika Hui Pū ʻIa i kahi ʻae kūloko [32] ka mea e ʻae ai i ka hoʻohana like ʻana o Remdesivir me ka lāʻau Baricitinib, i ka mālama ʻana i nā mea maʻi me ka maʻi coronavirus koʻikoʻi a me ka pono o ka oxygenation a i ʻole ka ea.
Nowemapa 20, 2020 Hoʻohou:
Ua ʻōlelo aʻoaʻo aku ka WHO e kūʻē i ka hoʻohana ʻana o Remdesivir i ka mālama ʻana i nā mea maʻi me COVID-19 ma muli o ka nele o ka ʻikepili paʻa e hōʻike ana e hōʻemi ana ʻo Remdesivir i ka helu make.
4. Dexamethasone
ʻO Dexamethasone kahi ʻano o ka corticosteroid i hoʻohana ākea ʻia i nā mea maʻi me nā pilikia hanu mau, e like me ka hānō, akā hiki nō ke hoʻohana ʻia i nā pilikia ʻino ʻē aʻe, e like me ka arthritis a me ka ʻili. Ua hoʻāʻo ʻia kēia lāʻau lapaʻau ma ke ʻano he ala e hōʻemi ai i nā ʻōuli o COVID-19, no ka mea hiki ke kōkua i ka hōʻemi ʻana i ka mumū i ke kino.
Wahi a kahi noiʻi e hana ʻia ma UK [18], dexamethasone ʻike ʻia ʻo ia ka lāʻau mua i hoʻāʻo e hoʻoliʻiliʻi nui i ka make o nā mea maʻi maʻi nui me COVID-19. Wahi a nā hopena o ke aʻo ʻana, ua hiki i ka dexamethasone ke hoʻemi i ka helu make a hiki i nā de 28 mau lā ma hope o ka maʻi ʻana me ka coronavirus hou, keu hoʻi i ka poʻe e pono e kōkua ʻia me ka ventilator a i ʻole e lawelawe i ka oxygen.
He mea nui e hoʻomanaʻo ʻaʻole hoʻopau ka dexamethasone i ka coronavirus mai ke kino, kōkua wale nō e hōʻoluʻolu i nā ʻōuli a hōʻalo i nā pilikia koʻikoʻi hou aʻe.
Iune 19, 2020 Hoʻohou:
Ua paipai ka hui o nā maʻi kūpilikiʻi Brazil i ka hoʻohana ʻana o dexamethasone no 10 mau lā no ka mālama ʻana i nā mea maʻi āpau me COVID-19 i ʻae ʻia i ka ICU me ka ea ea a i ʻole nā mea e pono ai ka oxygen. Eia nō naʻe, ʻaʻole pono e hoʻohana ʻia nā corticosteroids i nā hihia māmā a i ʻole ma ke ʻano he pale i ka maʻi [19].
Hoʻohou i Iulai 17, 2020:
Wahi a ka ʻepekema noiʻi i hana ʻia ma United Kingdom [24], ka lapaʻau ʻana me dexamethasone no 10 mau lā ma ka lālani me he mea lā e hoʻēmi ana i ka nui o ka make ma nā mea maʻi me ka maʻi ʻino loa e ka coronavirus hou, ka poʻe e pono ai ka ea. I kēia mau hihia, ua emi ka helu make mai 41.4% a 29.3%. I nā mea maʻi ʻē aʻe, ʻaʻole hōʻike ka hopena o ka mālama ʻana me dexamethasone i nā hopena i kaha ʻia.
Hoʻohou i Kepakemapa 2, 2020:
Kuhi ʻia kahi meta-analysis e pili ana i nā hoʻokolohua 7 maʻi [29] ua hoʻoholo ʻo ka hoʻohana ʻana o dexamethasone a me nā corticosteroids ʻē aʻe hiki, i ka ʻoiaʻiʻo, hoʻemi i ka make ma nā mea maʻi maʻi nui i hoʻopili ʻia me COVID-19.
Hoʻohou i Kepakemapa 18, 2020:
ʻO ka European Medicines Agency (EMA) [30] ʻae ʻia ka hoʻohana ʻana o dexamethasone i ka mālama ʻana i nā ʻōpio a me nā mākua i loaʻa i ka coronavirus hou, ka mea e pono ai ke kākoʻo oxygen a i ʻole ka ʻea ea.
5. ʻO Hydroxychloroquine a me chloroquine
ʻO Hydroxychloroquine, a me chloroquine, ʻelua mau mea i hoʻohana ʻia i ka mālama ʻana i nā mea maʻi me ka malaria, lupus a me kekahi mau pilikia olakino ʻē aʻe, akā ʻaʻole ia i manaʻo ʻia he palekana i nā hihia āpau o COVID-19.
Hana ʻia ma Falani [4] a ma Kina [5], hōʻike i nā hopena hoʻohiki o chloroquine a me hydroxychloroquine i ka hōʻemi ʻana i ka amo viral a me ka hoʻēmi ʻana i ka lawe ʻana o ka maʻi i loko o nā hunaola, e hoʻemi ana i ka hiki o ka maʻi e hoʻonui, e hāʻawi ana, no laila, ʻoi aku ka wikiwiki. Eia nō naʻe, ua hana ʻia kēia mau noiʻi ma nā laʻana liʻiliʻi a ʻaʻole maikaʻi nā hōʻike āpau.
I kēia manawa, e like me ka Ministry of Health o Brazil, hiki ke hoʻohana ʻia ka chloroquine i ka poʻe i ʻae ʻia i ka haukapila, no 5 mau lā, ma lalo o ka nānā mau ʻana, e nānā i ke ʻano o nā hopena ʻē aʻe e like me nā pilikia puʻuwai a i ʻole nā loli i ka ʻike. .
ʻApelila 4, 2020 Hoʻohou:
ʻO kekahi o nā noi e hoʻomau nei, me ka hoʻohana pū ʻia o hydroxychloroquine a me ka antibiotic azithromycin [9], ma Palani, hōʻike ʻia nā hopena i ka hopena o kahi hui o 80 mau maʻi me nā ʻōuli maʻamau o COVID-19. I kēia hui, ua ʻike ʻia ka hoʻoliʻiliʻi o ka viral viral o ka coronavirus hou i loko o ke kino, ma hope o 8 mau lā o ka mālama ʻana, ma lalo o ka awelika o 3 mau pule i hōʻike ʻia e ka poʻe ʻaʻole i mālama ʻia i kekahi ʻano lapaʻau kikoʻī.
I kēia hoʻokolokolo ʻana, o nā maʻi he 80 i hoʻopaʻa ʻia, hoʻokahi wale nō kanaka i pau i ka make, no ka mea, ua hoʻokomo ʻia ʻo ia i ka haukapila i kahi wā i hele mua loa loa ʻia o ka maʻi, a ʻo ia paha ka mea i keʻakeʻa i ka lāʻau.
Ke hoʻomau nei kēia mau hopena i ke kākoʻo ʻana i ke kumumanaʻo e hiki ke hoʻohana i ka hydroxychloroquine i ala palekana e mālama ai i ka maʻi COVID-19, keu hoʻi i nā hihia akahai a ahuwale, me ka hoʻoliʻiliʻi o ka lawe ʻia ʻana o ka maʻi. Eia nō naʻe, pono ke kali no nā hopena o nā noi ʻē aʻe e lawe ʻia nei me ka lāʻau, e loaʻa ai nā hopena me kahi laʻana heluna kanaka nui aku.
ʻApelila 23, 2020 Hoʻohou:
Ua ʻae ka Federal Council of Medicine o Brazil i ka hoʻohana ʻana o Hydroxychloroquine me ka hui pū me Azithromycin i ka manaʻo o ke kauka, i nā mea maʻi me nā ʻano akahai a akahai paha, akā ʻaʻole pono nā ICU e komo, kahi e loaʻa ai nā maʻi viral ʻē aʻe, e like me Influenza a i ʻole H1N1. , a hōʻoia ʻia ka hōʻailona o COVID-19 [12].
No laila, no ka loaʻa ʻole o nā hopena ʻepekema ikaika, e hoʻohana wale ʻia kēia hui ʻana o nā lāʻau me ka ʻae o ka mea maʻi a me ka ʻōlelo a ke kauka, ma hope o ka nānā ʻana i nā pilikia e hiki ke loaʻa.
Mei 22, 2020 Hoʻohou:
Wahi a kahi noiʻi i lawe ʻia ma United States me 811 mau mea maʻi [13], ka hoʻohana ʻana o Chloroquine a me Hydroxychloroquine, pili a pili ʻole paha me azithromycin, me he mea lā ʻaʻole he hopena maikaʻi i ka mālama ʻia ʻana o COVID-19, me he mea lā e pāpālua ana i ka nui o ka make o nā mea maʻi, ʻoiai ua hoʻonui kēia mau lāʻau i ka pilikia o nā pilikia o ka naʻau, ʻo ka arrhythmia a me ka atrial fibrillation.
I kēia manawa, ʻo kēia kahi aʻo nui loa i hana ʻia me ka hydroxychloroquine a me ka chloroquine. Ma muli o ka hopena i hōʻike ʻia e kūʻē i nā mea i ʻōlelo ʻia e pili ana i kēia mau lāʻau, pono hou ʻia kahi mau aʻo ʻana.
Mei 25, 2020 Hoʻohou:
Ua hoʻomaha kuikawa ka World Health Organization (WHO) i ka noiʻi e pili ana i ka hydroxychloroquine i hoʻohui ʻia i kekahi mau ʻāina. Pono e mālama ʻia ka hoʻomaha a hiki i ka hōʻoia ʻana o ka palekana o ka lāʻau.
Mei 30, 2020 Hoʻohou:
ʻO ka mokuʻāina ʻo Espírito Santo, ma Brazil, ua hoʻihoʻi i ka hōʻike o ka hoʻohana ʻana o chloroquine i nā mea maʻi me COVID-19 i kahi kūlana koʻikoʻi.
Eia hou, nā luna loio mai ka Federal Public Ministry o São Paulo, Rio de Janeiro, Sergipe a me Pernambuco e noi no ka hoʻomaha ʻana o nā rula e hōʻike ana i ka hoʻohana ʻana o hydroxychloroquine a me chloroquine i ka mālama ʻana i nā mea maʻi me COVID-19.
Iune 4, 2020 Hoʻohou:
Ua kāpae ka makaseta Lancet i ka paʻi o ke aʻo ʻana o 811 mau mea maʻi e hōʻike ana ʻaʻole i loaʻa nā hopena maikaʻi o ka hoʻohana ʻana i ka hydroxychloroquine a me ka chloroquine no ka mālama ʻana iā COVID-19, no ka paʻakikī i ke kiʻi ʻana i ka ʻike mua i hōʻike ʻia i loko o ka noiʻi.
Iune 15, 2020 Hoʻohou:
ʻO ka FDA, ʻo ia ke kino nui o ka lāʻau hoʻomalu lāʻau a ʻAmelika Hui Pū ʻIa, ua kāpae i ka ʻae kūpilikiʻi no ka hoʻohana ʻana i ka chloroquine a me ka hydroxychloroquine i ka mālama ʻia ʻana o COVID-19 [17], ke hōʻoia nei i ke kiʻekiʻe o ka hopena o ka lāʻau a me nā ʻike haʻahaʻa haʻahaʻa no ka mālama ʻana i ka coronavirus hou.
Hoʻohou i Iulai 17, 2020:
ʻO ka Hui Pūleka o nā maʻi Infectious ʻo Brazil [25] Paipai iā ia e haʻalele ʻia ka hoʻohana ʻana o hydroxychloroquine i ka mālama ʻana iā COVID-19, i kēlā me kēia wā o ka maʻi.
Lulai 23, 2020 Hoʻohou:
Wahi a kahi aʻo Brazil [27], hana pū ʻia ma waena o Albert Einstein, HCor, Sírio-Libanês, Moinhos de Vento, Oswaldo Cruz a me Beneficência Portuguesa Hospitals, ka hoʻohana ʻia ʻana o ka hydroxychloroquine, pili a ʻaʻole paha me azithromycin, me he mea lā ʻaʻole he hopena i ka mālama ʻana i nā mea akahai nā mea maʻi me ka coronavirus hou.
6. ʻO Colchisin
Wahi a kahi noiʻi i mālama ʻia ma Kanada [38], colchisin, kahi lāʻau i hoʻohana ākea ʻia i ka mālama ʻana i nā pilikia rheumatological, e like me ka gout, hiki ke kōkua i ka mālama ʻana i nā mea maʻi me COVID-19.
Wahi a nā kānaka noiʻi, ʻo ka hui o nā mea maʻi i mālama ʻia me kēia lāʻau mai ka ʻike ʻia o ka maʻi, ke hoʻohālikelike ʻia me ka hui i hoʻohana i kahi placebo, ua hōʻike i ka hoʻoliʻiliʻi o ka makaʻu o ka maʻi. Eia hou, ua hōʻike pū ʻia kahi hōʻemi o ka haukapila a me nā helu make.
7. Mefloquine
ʻO Mefloquine kahi lāʻau i hōʻike ʻia no ka pale a me ka mālama ʻana i ka malaria, i ka poʻe e manaʻo e huakaʻi i nā wahi hopena. Ma muli o nā noiʻi i hana ʻia ma Kina a me Italia[6], kahi regimen therapeutic regimen kahi e hui pū ʻia ai ka mefloquine me nā lāʻau ʻē aʻe i Rukia e hōʻoia i ka maikaʻi o ka kaohi ʻana i ka maʻi COVID-19, akā ʻaʻohe hopena hope loa.
No laila, ʻaʻole i paipai ʻia ka hoʻohana ʻana i ka mefloquine e mālama i ka maʻi me ka coronavirus hou no ka mea he nui nā noiʻi e pono ai e hōʻoia i kona pono a me ka palekana.
8. ʻO Tocilizumab
ʻO Tocilizumab kahi lāʻau e hōʻemi i ka hana o ka ʻōnaehana pale a, no laila, hoʻohana maʻamau ʻia i ka mālama ʻana i nā mea maʻi me ka rheumatoid arthritis, e hoʻēmi ai i ka pane o ke kūpikipiki nui, e hōʻemi ana i nā mumū a me nā hōʻailona hōʻoluʻolu.
Ke aʻo ʻia nei kēia lāʻau i mea e kōkua ai i ka mālama ʻana i COVID-19, keu hoʻi i nā pae holomua o ka maʻi, ke nui nā mea kuni e hoʻopuka ʻia e ka ʻōnaehana pale, kahi e hōʻeha ai i ke ʻano maʻi.
Wahi a kahi noiʻi ma Kina [10] i nā maʻi he 15 i hoʻopili ʻia me COVID-19, ua ʻoi aku ka maikaʻi o ka hoʻohana ʻana o tocilizumab a hōʻemi i nā hopena ʻē aʻe, ke hoʻohālikelike ʻia i nā corticosteroids, ʻo ia nā lāʻau i hoʻohana mau ʻia e kaohi i ka mumū i hana ʻia e ka pane immune.
Eia nō naʻe, pono e hoʻokō ʻia nā ʻike hou aku, e ʻike i ke ʻano o ka mahele lāʻau maikaʻi loa, e hoʻoholo i ke ʻano hoʻomalu a ʻike i nā hopena ʻē aʻe e hiki ai.
ʻApelila 29, 2020 Hoʻohou:
Wahi a kahi noiʻi hou i hana ʻia ma Kina me 21 mau maʻi i maʻi ʻia me COVID-19[14], hiki ke hōʻemi ʻia nā ʻōuli o ka maʻi ma hope koke o ka lawelawe ʻana o ka lāʻau, ka hoʻohaʻahaʻa ʻana i ke kuni, me ka hoʻōla ʻana i ka manaʻo o ka paʻa i ka umauma a me ka hoʻomaikaʻi ʻana i nā pae o ka oxygen.
Ua hana ʻia kēia aʻo ʻana i nā mea maʻi me nā ʻōuli koʻikoʻi o ka maʻi a hōʻike ʻia e hoʻomaka koke ʻia ka mālama ʻana me ka tocilizumab ke hele ka mea maʻi mai kahi kūlana kūpono i kahi kūlana koʻikoʻi o ka maʻi me ka coronavirus hou.
Hoʻohou i Iulai 11, 2020:
ʻImi hou e ke Kulanui o Michigan ma United States [28], hoʻopau i ka hoʻohana ʻana o tocilizumab i nā mea maʻi me COVID-19 e hoʻoliʻiliʻi ana i ka nui o ka make ma nā mea maʻi i hoʻoliʻiliʻi ʻia, ʻoiai ua hoʻonui ʻia ka makaʻu o nā maʻi ʻē aʻe.
9. Palapala hoʻohalahala plasma
ʻO Convalescent plasma kahi ʻano mālama olaola kahi i lawe ʻia kahi laʻana koko, mai ka poʻe i loaʻa mua i ka coronavirus a i loaʻa hou ʻia, a laila hana i kekahi hana centrifugation e hoʻokaʻawale i ka plasma mai nā hunaola ʻulaʻula. ʻO ka mea hope loa, ua hoʻokomo ʻia kēia plasma i loko o ka mea maʻi e kōkua i ka ʻōnaehana pale pale kaua i ka maʻi.
ʻO ke kumumanaʻo ma hope o kēia ʻano lapaʻau ʻo ia nā mea ʻino i hana ʻia e ke kino o ke kanaka i loaʻa i ka maʻi, a ua waiho ʻia i loko o ka plasma, hiki ke hoʻoili ʻia i ke koko o kekahi kanaka e noho mau nei me ka maʻi, e kōkua ana e hoʻoikaika. ke kūlana. ka palekana a me ka kōkua ʻana i ka hoʻopau ʻana i ka maʻi.
Wahi a ka Note Note No. 21 i hoʻokuʻu ʻia e Anvisa, ma Brazil, hiki ke hoʻohana ʻia ka plasma convalescent ma ke ʻano he lāʻau hoʻokolohua i nā mea maʻi i loaʻa i ka coronavirus hou, ke mālama ʻia nā lula Health Surveillance āpau. Eia hou, ʻo nā hihia āpau e hoʻohana i ka plasma convalescent no ka mālama ʻana i COVID-19 pono e hōʻike ʻia i ka General Coordination of Blood and Blood Products of the Ministry of Health.
10. ʻO Avifavir
ʻO Avifavir kahi lāʻau i hana ʻia ma Rūkia nona ka mea hana i loko o ka waiwai favipiravir, ka mea e like me ka Russian Direct Investment Fund (RDIF) [21] hiki iā ia ke mālama i ka maʻi coronavirus, ke komo pū ʻia i ka mālama ʻana a me nā kaohi pale o COVID-19 ma Lūkia.
Wahi a nā noiʻi i mālama ʻia, ma loko o 10 mau lā, ʻaʻohe hopena ʻē aʻe o Avifavir a, i loko o nā lā 4, 65% o nā mea maʻi i loaʻa i kahi hōʻike maikaʻi ʻole no COVID-19.
11. ʻO Baricitinib
Ua ʻae ka FDA i ka hoʻohana pilikia ʻana o ka lāʻau Baricitinib i ka mālama ʻana i nā maʻi COVID-19 koʻikoʻi [32]i hui pū ʻia me Remdesivir. ʻO Baricitinib kahi mea e hōʻemi ai i ka pane o ka ʻōnaehana pale, e hoʻemi ana i ka hana o nā enzyme e hāpai i ka hoʻā ʻana a hoʻohana mua ʻia i nā hihia o ka rheumatoid arthritis.
Wahi a ka FDA, hiki ke hoʻohana ʻia kēia hui ʻana i nā mea maʻi makua a me nā keiki i ʻoi aku ma mua o 2 mau makahiki, i ka haukapila a me ka pono o ka mālama ʻana me ka oxygen a me ka ea ea.
12. EXO-CD24
ʻO EXO-CD24 kahi lāʻau i hōʻike ʻia no ka mālama ʻana i ka maʻi ʻaʻai ovarian a ua hiki ke hoʻōla iā 29 o 30 mau maʻi me COVID-19. Eia nō naʻe, ke hoʻomau ʻia nei nā noiʻi hou aku, me ka nui o ka poʻe, me ka pahuhopu o ka hōʻoia ʻana inā e maikaʻi kēia lāʻau i ka mālama ʻana i ka maʻi a me ka lāʻau i manaʻo ʻia he palekana no ka hoʻohana.
Nā koho hoʻoponopono kūlohelohe no ka coronavirus
Ma kēia manawa ʻaʻohe hōʻike kūlohelohe i hōʻoia ʻia e hoʻopau i ka coronavirus a kōkua i ka hoʻōla iā COVID-19, eia naʻe, ʻike ʻo WHO i ka mea kanu. Artemisia annua hiki ke kōkua i ka lāʻau [11], keu hoʻi i nā wahi i ʻoi aku ka paʻakikī o ke kiʻi ʻana i nā lāʻau a hoʻohana ʻia ka mea kanu i nā lāʻau lapaʻau kuʻuna, e like me ka hihia ma nā wahi like ʻole o ʻApelika.
Nā lau o ka mea kanu Artemisia annua hoʻohana mau ʻia ma ʻApelika e kōkua i ka mālama ʻana i ka malaria a, no laila, ʻike ʻo WHO he pono no nā noiʻi e hoʻomaopopo inā hiki ke hoʻohana ʻia ka mea kanu i ka mālama ʻana o COVID-19, ʻoiai ua hōʻike ʻia kekahi mau lāʻau synthetic e kūʻē i ka malaria i nā hopena i hoʻohiki ʻia. .
Eia nō naʻe, mea nui e hoʻomanaʻo ʻaʻole i hoʻokūpaʻa ʻia ka hoʻohana ʻana o nā mea kanu e kūʻē iā COVID-19 a pono e ʻimi hou aku.