Pellagra
Anter
He aha ka pellagra?
ʻO Pellagra kahi maʻi i hoʻokumu ʻia e nā haʻahaʻa haʻahaʻa o ka niacin, i ʻike ʻia ʻo ka huaʻai B-3. Kaha ʻia e dementia, diarrhea, a me dermatitis, i ʻike ʻia ʻo "the three Ds". Inā haʻalele ʻole ʻia, hiki i ka pellagra ke make.
ʻOiai ʻoi aku ka liʻiliʻi o ka mea ma mua o ka wā ma mua, mahalo i ka holomua i ka hana ʻana i ka meaʻai, he pilikia nō ia i nā ʻāina kūkulu he nui. Hiki iā ia ke hoʻopili i ka poʻe nona nā kino e komo ʻole ʻole i ka niacin.
He aha nā hōʻailona?
ʻO nā ʻōuli nui o ka pellagra he dermatitis, dementia, a me ka diarrhea. ʻO kēia no ka mea ʻike nui ʻia ka hemahema o ka niacin i nā ʻāpana o ke kino me nā helu kiʻekiʻe o ka huli ʻana o ke kelepona, e like me kou ʻili a i ʻole ka gastrointestinal tract.
ʻO ka dermatitis e pili ana i ka pellagra ka mea maʻamau i ka helehelena ma ka maka, nā lehelehe, nā wāwae, a me nā lima. I kekahi poʻe, hana nā dermatitis a puni ka ʻāʻī, kahi hōʻailona i kapa ʻia ʻo Casal lei.
ʻO nā hōʻailona dermatitis hou aʻe:
- ʻulaʻula, ʻili flaky
- mai nā ʻula a me nā kala
- mānoanoa, pala, wīwī, a i ʻole ʻili naha
- ʻili, ʻōwili nā ʻili o ka ʻili
I kekahi mau hihia, ʻike koke ʻia nā ʻōuli neurological o pellagra, akā paʻakikī pinepine lākou e ʻike. Ke holo nei ka maʻi, hiki i nā ʻōuli dementia ke hoʻopili ʻia:
- aloha ʻole
- kaumaha
- huikau, huhū, a i ʻole hoʻololi i ke ʻano
- ʻeha poʻo
- hoʻomaha ʻole a hopohopo paha
- disorientation a kuhi hewa paha
ʻO nā hōʻailona pellagra ʻē aʻe e pili pū me:
- ʻeha ma nā lehelehe, elelo, a i ʻole gums
- hoʻēmi ʻai
- pilikia i ka ʻai ʻana a me ka inu ʻana
- nausea a me ka luaʻi
He aha ke kumu?
ʻElua ʻano pellagra, i ʻike ʻia ʻo pellagra mua a me pellagra lua.
Hoʻokumu ʻia ka pellagra mua e nā papaʻai haʻahaʻa i ka niacin a i ʻole ka tryptophan. Hiki ke hoʻololi ʻia ʻo tryptophan i niacin i loko o ke kino, no laila ʻaʻole lawa ka nui e hiki ai ke hōʻemi i ka niacin.
ʻO ka pellagra mua ka mea maʻamau i nā ʻāina kūkulu e hilinaʻi i ka kulina ma ke ʻano he meaʻai nui. Aia i loko o Corn ka niacytin, kahi ʻano o ka niacin i hiki ʻole i nā kānaka ke ʻeli a omo ke ʻole e hoʻomākaukau pono.
Kū ka pellagra lua ke hiki ʻole i kou kino ke komo i ka niacin. Nā mea i hiki ke pale i kou kino mai ke komo ʻana i ka niacin me:
- ʻalekohola
- nā maʻi ʻai
- kekahi mau lāʻau lapaʻau, e like me anti-convulsants a me nā lāʻau immunosuppressive
- nā maʻi gastrointestinal, e like me ka maʻi o Crohn a me ka ulcerative colitis
- cirrhosis o ke ake
- tumors carcinoid
- Maʻi ʻo Hartnup
Pehea ia ʻike?
Hiki i ka Pellagra paʻakikī ke kuhi no ka mea ke kumu ia o kahi o nā hōʻailona. ʻAʻole nō hoʻi kahi hoʻokolohua kikoʻī no ka hōʻoia ʻana i ka hemahema niacin.
Ma kahi o, e hoʻomaka kāu kauka ma ka nānā ʻana i nā pilikia o ka gastrointestinal, nā ʻōpala, a i ʻole nā loli i kou ʻano noʻonoʻo. Hiki paha iā lākou ke hōʻole i kou mimi.
I nā manawa he nui, ke kuhi ʻana i ka pellagra e pili ana i ka ʻike ʻana inā pane kāu mau hōʻailona i nā pāʻina niacin.
Pehea e mālama ʻia ai?
Mālama ʻia ka pellagra mua me nā loli o ka papaʻai a me ka niacin a i ʻole ka nikotinamide kōkua. Pono paha e hāʻawi intravenously. ʻO Nicotinamide kekahi ʻano o ka wikamina B-3. Me ka lapaʻau mua, nui ka poʻe e hana i kahi ola hou a hoʻomaka i ka maikaʻi i loko o kekahi mau lā o ka hoʻomaka ʻana o ka lāʻau. Mahuahua mau paha ka hoʻomaikaʻi ʻana o ka ʻili Eia nō naʻe, inā ʻaʻole mālama ʻia, pellagra mua ke kumu o ka make ma hope o ʻehā a ʻelima mau makahiki paha.
Mālama maʻamau ka mālama ʻana i ka pellagra lua i ka mālama ʻana i ke kumu kumu. Eia nō naʻe, pane maikaʻi kekahi mau hihia o ka pellagra lua i ka lawe ʻana i ka niacin a i ʻole ka nicotinamide ma ka waha a i ʻole ke aniani.
ʻOiai ke ola nei mai ka pellagra mua a i ʻole ʻelua paha, he mea nui e mālama i nā huehue āpau a pale ʻia me ka pale o ka lā.
Noho me ka pellagra
ʻO Pellagra kahi kūlana koʻikoʻi i hoʻokumu ʻia e nā pae haʻahaʻa o ka niacin, ma muli o ka malnutrity a i ʻole kahi pilikia omo. Inā haʻalele ʻole ʻia, hiki i ka make ke make. ʻOiai ka maikaʻi o ka pane ʻana o ka pellagra mua i ka hoʻohuihui niacin, hiki i ka pellagra lua ke ʻoi aku ka paʻakikī e mālama, ma muli o ke kumu kumu.