Nā Hana Osteoporosis

Anter

• Osteoporosis
• Nā kumu a me nā kumu pilikia
• Nā lāʻau osteoporosis
• Nā Bisphosphonates
• Antibody
• ʻO Denosumab
• Romosozumab
• Nā lāʻau e pili ana i ka Hormone
• Nā modulator receptor estrogen koho (SERMs)
• Kalepona
• Nā hormona parathyroid (PTHs)
• Hoʻoikaika Hormone
• Kalipuna a me ka wikamina D
• ʻOihana hoʻoikaika kino
• Outlook

Nā ʻoiaʻiʻo wikiwiki

1. ʻO Osteoporosis kahi kūlana e wāwahi ai kou mau iwi ma mua o ke kūkulu hou ʻana.
2. Hoʻopili maʻamau ka mālama ʻana i ka hui pū ʻana o nā lāʻau a me nā loli nohona.
3. ʻO ke ala ʻoi loa e pale aku i ka nalo ʻana o ka iwi ka lawe ʻana i nā lāʻau i kuhikuhi ʻia.

Osteoporosis

ʻO nā iwi i loko o kou kino nā meaola ola e wāwahi mau a hoʻololi iā lākou iho me nā mea hou. Me ka osteoporosis, haki wikiwiki kou mau iwi ma mua o ko lākou ulu hou ʻana. ʻO kēia ke kumu e lilo ai lākou i mea haʻahaʻa, porous, a me nā mea palupalu.

Hoʻonāwaliwali kēia i kou mau iwi a hiki ke alakaʻi i nā haki a me nā haki hou.

ʻAʻohe mea ola no ka osteoporosis, akā aia kekahi mau hōʻailona e kōkua ai i ka pale a mālama ʻana ke ʻike ʻia ka maʻi. ʻO ka pahuhopu o ka mālama ʻana e pale a hoʻoikaika i kou mau iwi.

Hoʻopili maʻamau ka mālama ʻana i ka hui pū ʻana o nā lāʻau a me nā loli nohona e kōkua i ka lohi o ka haʻihaʻi iwi e kou kino, a i kekahi mau hihia, e kūkulu hou i ka iwi.

Nā kumu a me nā kumu pilikia

Loaʻa ka hapa nui o ka poʻe i ka nui o ka iwi a me ka momona i ka wā o 20 mau makahiki. Ke ʻelemakule nei ʻoe, ua lilo ka iwi kahiko i ka wikiwiki ma mua o ka hiki i kou kino ke pani iā ​​ia. Ma muli o kēia, aia i ka poʻe mākua ka nui o ka maka o ka osteoporosis.

ʻOi aku ka nui o ka makaʻu o nā wahine i ka hoʻomōhala ʻana i ka osteoporosis no ka mea maʻamau ka iwi o lākou i ka lahilahi ma mua o nā kāne. ʻO ka Estrogen, kahi hōmona e kū i nā kiʻekiʻe kiʻekiʻe i nā wahine ma mua o nā kāne, kōkua i ka pale ʻana i nā iwi.

ʻO nā wahine e hele nei i loko o ka menopause ʻike i ka hōʻemi o nā pae estrogen, kahi e alakaʻi ai i ka haʻihaʻi iwi wikiwiki a hiki i ka hopena o nā iwi palupalu.

ʻO nā kumu ʻē aʻe e pili pū me:

• puhipaka
• kekahi mau lāʻau, e like me nā steroid, proton pump inhibitors, a me kekahi mau lāʻau i hopu ʻia
• hana maikaʻi ʻole
• kekahi mau maʻi, e like me rheumatoid arthritis (RA) a me myeloma maha

Nā lāʻau osteoporosis

ʻO ke ala ʻoi loa e pale aku i ka nalo ʻana o ka iwi ka lawe ʻana i nā lāʻau i kuhikuhi ʻia, e like me nā lāʻau i helu ʻia ma lalo.

Nā Bisphosphonates

ʻO nā Bisphosphonates nā ʻano lāʻau osteoporosis ʻoi loa. ʻO lākou ka maʻamau o nā lapaʻau mua e paipai ʻia no nā wahine postmenopausal.

Eia kekahi laʻana o nā bisphosphonates:

• alendronate (Fosamax), kahi lāʻau lapaʻau waha e lawe ai ka poʻe i kēlā me kēia lā a hoʻokahi paha i kēlā me kēia pule
• ibandronate (Boniva), hiki ke loaʻa ma ke ʻano he papaha waha waha a i ʻole he ʻinikua intravenous i loaʻa iā ʻoe i ʻehā mau manawa i kēlā me kēia makahiki
• risedronate (Actonel), loaʻa i kēlā me kēia lā, i kēlā me kēia pule, a i ʻole nā ​​helu mahina ma ka papaha waha
• zoledronic acid (Reclast), loaʻa ma ke ʻano he infusion intravenous e loaʻa iā ʻoe i kēlā me kēia i hoʻokahi a i ʻole ʻelua mau makahiki

Antibody

Aia he mau lāʻau lapaʻau antibody ʻelua ma ka mākeke.

ʻO Denosumab

Denosumab (Prolia) loulou i kahi protein i kou kino e pili ana i ka haʻihaʻi iwi. Hoʻohiohi ia i ke kaʻina o ka haki iwi. Mālama pū kekahi ia i ka nui o ka iwi.

Hele mai ʻo Denosumab ma ke ʻano he injection i loaʻa iā ʻoe i kēlā me kēia ʻeono mau mahina.

Romosozumab

Kōkua ka mea hou antibody romosozumab (Evenity) i ka hoʻonui ʻana i ka hana iwi. Ua ʻae ʻia e ka Food and Drug Administration (FDA) i ʻApelila o 2019. Kuhi ʻia no nā wahine postmenopausal me ka nui o ka haki o ka haʻi. Hoʻopili kēia i nā wahine i:

• he mau kumu pilikia no ka haki
• he moʻolelo o ka haki
• ʻaʻole i pane a i ʻole hiki ʻole ke lawe i nā lāʻau osteoporosis ʻē aʻe

Hele mai ʻo Romosozumab ma ke ʻano he ʻelua injection. Loaʻa iā ʻoe i hoʻokahi manawa i ka mahina a hiki i 12 mau mahina.

Hele mai ʻo Romosozumab me nā ʻōlelo aʻoaʻo pahu, ʻo ia nā ʻōlelo aʻoaʻo koʻikoʻi a ka FDA. Hiki ke hoʻonui i kou makaʻu o ka puʻuwai puʻuwai, hahau ʻana, a me ka maʻi maʻi maʻi. ʻAʻole pono ʻoe e lawe i ka romosozumab inā loaʻa ʻoe i ka puʻuwai puʻuwai a i ʻole hahau i loko o ka makahiki i hala.

Nā lāʻau e pili ana i ka Hormone

Hiki ke kuhikuhi ʻia i kekahi mau lāʻau i loaʻa nā hopena e like me ka hormone e mālama ai i ka osteoporosis.

Nā modulator receptor estrogen koho (SERMs)

Hoʻololi hou nā modulator receptor estrogen (SERMs) i nā hopena mālama iwi o ka estrogen.

ʻO Raloxifene (Evista) kekahi ʻano o SERM. Loaʻa iā ia ma ke ʻano he papa ʻōlelo waha i kēlā me kēia lā.

Kalepona

ʻO Calcitonin kahi hōmona a ka thyroid gland e hana ai. Kōkua ia i ka mālama ʻana i nā pae calcium i loko o ke kino.

Hoʻohana nā kauka i ka calcitonin synthetic (Fortical, Miacalcin) e mālama ai i ka osteoporosis ʻōiwi i kekahi mau wahine i hiki ʻole ke lawe i nā bisphosphonates.

ʻO ka lepili hoʻohana ʻole ʻia, hiki i ka calcitonin ke hōʻoluʻolu i ka ʻeha i kekahi poʻe i loaʻa nā haʻihaʻi o ke kuamoʻo. Loaʻa ʻo Calcitonin e ka nasal spray a i ʻole ka injection.

Nā hormona parathyroid (PTHs)

Mālama nā hormones Parathyroid (PTHs) i nā pae o ka calcium a me nā phosphate i kou kino. Hiki i nā mālama ʻana me ka PTH synthetic ke hāpai i ka ulu iwi hou.

ʻElua mau koho i komo pū me:

• teriparatide (Forteo)
• abaloparatide (Tymlos)

Loaʻa ʻo Teriparatide ma ke ʻano he inikua mālama pono ʻia i kēlā me kēia lā. Eia nō naʻe, pipiʻi kēia lāʻau a mālama ʻia no nā poʻe me ka osteoporosis koʻikoʻi i hiki ʻole ke hoʻomanawanui i nā mālama ʻē aʻe.

ʻO Abaloparatide kahi hana PTH synthetic ʻē aʻe i ʻae ʻia ma 2017. E like me teriparatide, loaʻa kēia lāʻau lapaʻau ma ke ʻano he inikū ponoʻī i kēlā me kēia lā. Eia nō naʻe, he kumukūʻai nō hoʻi ia a hoʻohana mau ʻia no nā poʻe me ka osteoporosis koʻikoʻi ke koho maikaʻi ʻole ʻia nā lāʻau ʻē aʻe.

Hoʻoikaika Hormone

No nā wahine i ka menopause, ka hōʻaila hōmona - i kapa ʻia hoʻi ʻo ka hōʻaihoʻi hou hormon - he koho lapaʻau. Akā maʻamau, ʻaʻole hoʻohana nā kauka iā ia ma ke ʻano he laina pale mua no ka mea hiki ke hoʻonui i ka makaʻu o:

• hahau
• maʻi hohola
• maʻi ʻaʻai umauma
• huʻi koko

ʻAe ʻia ʻo Hormone therapy e hoʻohana i ka pale ʻana i ka osteoporosis, akā hiki ke hoʻohana ʻia i kahi lepili inoa ʻole no ka mālama ʻana.

Hiki i ka Hormone therapy ke hoʻopili i ka estrogen wale nō, a i ʻole estrogen i hui pū ʻia me ka progesterone. Hele mai ia ma ke ʻano he papa haʻi waha, ʻili ʻili, ʻoki, a me ka holika. Hoʻohana pinepine ʻia nā papa a me nā pale.

Lawe ʻia i kēlā me kēia lā, hoʻopili ʻia nā papa:

• Premarin
• Menest
• Estrace

Hoʻohana hoʻokahi a ʻelua paha i kēlā me kēia pule, hoʻokomo nā pākuʻi:

• ʻO Climara
• ʻO Vivelle-Dot
• ʻO Minivelle

Kalipuna a me ka wikamina D

ʻOiai ke lawe nei ʻoe i kekahi o nā lāʻau i helu ʻia ma luna, paipai nā kauka e kiʻi i ka nui o ka puna a me ka huaola D i kāu papaʻai. ʻO ia no ka mea hiki i kēia mineral a me ka wikamina pū ke kōkua i ka lohi o ka nalo ʻana o ka iwi.

ʻO ka kalipuna ka mineral mua i loko o kou mau iwi, a kōkua ka wikamina D i kou kino e omo i ka puna e pono ai.

ʻO nā meaʻai momona ka momona

• huahana waiū
• mea kanu uliuli ʻōmaʻomaʻo
• hua palaoa a me nā berena
• huahana soy

Loaʻa ka hapa nui o nā cereala a me nā wai ʻalani me ka calcium i hoʻohui pū ʻia.

Paipai ka National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) i nā makahiki he 19-50 a me nā kāne he 19-70 mau makahiki e loaʻa iā 1,000 milligrams (mg) o ka calcium i kēlā me kēia lā.

Paipai lākou i nā wahine i piha i ka makahiki 51-70 a me kēlā me kēia mea ma luna o 70 e loaʻa iā 1,200 mg o ka calcium i kēlā me kēia lā.

Paipai pū ka NIAMS i nā mākua ma lalo o 70 e loaʻa i 600 mau ʻāpana honua (IU) o ka wikamina D i kēlā me kēia lā. Pono nā mākua ma luna o 70 mau makahiki i ka 800 IU o ka wikamina D i kēlā me kēia lā.

Inā ʻaʻole lawa ʻoe i ka calcium a i ʻole ka wikamina D mai kāu papaʻai, hiki iā ʻoe ke lawe i nā mea hoʻopihapiha e hōʻoia i ka loaʻa ʻana o ka nui i ʻōlelo ʻia.

ʻOihana hoʻoikaika kino

Kōkua ka hoʻoikaika i kou mau iwi. ʻO kēlā me kēia ʻano, kōkua ka hoʻoikaika kino i ka nalo ʻana o ka iwi e pili ana i ka makahiki a hiki ke hoʻomaikaʻi iki i ka iwi i kekahi mau hihia.

Hiki i ka hoʻoikaika kino ke kōkua i ka hoʻomaikaʻi ʻana i kou kūlana a me ke kaulike, e hoʻohaʻahaʻa ana i kou maka o ka hāʻule. Hiki ke hoʻohālikelike i nā haki liʻiliʻi.

Hoʻomaikaʻi ka hoʻomaʻamaʻa ikaika i nā iwi i kou mau lima a me ka iwi kuamoʻo luna. Hiki i kēia ke hoʻohālikelike i nā kaupaona manuahi, nā mīkini kaupaona, a i ʻole nā ​​kaula kūʻē.

ʻO ka hoʻoikaika kino e like me ka hele wāwae ʻana a i ʻole ka jogging ʻana, a me nā aerobics hopena haʻahaʻa e like me ka hoʻomaʻamaʻa elliptical a i ʻole ka paikikala ʻana, hiki ke pono pū kekahi. Hiki i nā mea ʻelua ke kōkua i ka hoʻoikaika ʻana i nā iwi i kou mau wāwae, pūhaka, a me ka iwi ʻaoʻao lalo.

Outlook

Hoʻopili ka Osteoporosis i nā poʻe he nui ma ka honua holoʻokoʻa, a ʻoiai ʻaʻohe mea ola i kēia manawa, loaʻa nā lāʻau. Hiki i nā lāʻau, ka hoʻōla hormonone, a me ka hoʻoikaika kino ke hoʻoikaika i kou mau iwi a lohi i ka nalo ʻana o ka iwi.

Inā loaʻa ʻoe i ka osteoporosis, e kamaʻilio me kāu kauka. Kūkākūkā i kēlā me kēia hana kūpono a me ka loli nohona. Hiki pū, hiki iā ʻoe ke hoʻoholo i kahi hoʻolālā lapaʻau e ʻoi aku ka maikaʻi iā ʻoe.