Maikaʻi ka Methotrexate no ka Rheumatoid Arthritis?

Anter

• Mālama iā RA me ka methotrexate
• Ka hoʻokō ʻana
• I ka hui pū me nā lāʻau ʻē aʻe
• Nā hopena ʻaoʻao o ka methotrexate
• E kamaʻilio me kāu kauka

ʻO Rheumatoid arthritis (RA) kahi maʻi autoimmune mau. Inā loaʻa iā ʻoe kēia ʻano, kamaʻāina ʻoe me ka pehu a me nā ami ʻehaʻeha o ke kino. ʻAʻole kēia mau ʻeha a me nā ʻeha e nā kūlohelohe a me nā waimaka e kū me ka ʻelemakule. Akā, kuhi hewa kāu ʻōnaehana pale i ka uhi ʻana o kou mau hui no nā mea komo hewa haole a laila hoʻouka i kou kino. ʻAʻohe mea ʻike maopopo no ke aha e hana ai kēia a no ke kumu e loaʻa ai kekahi i kēia maʻi.

ʻAʻohe mea ola i kēia manawa no RA, akā aia kekahi mau ala e mālama ai. Kau kauka paha kau kauka e hoʻolohi i ka holomua o ka maʻi a kāʻili paha i kāu ʻōnaehana pale. Hāʻawi paha lākou iā ʻoe i nā lāʻau e hōʻemi i ka mumū a me ka ʻeha o kou hono.

ʻO ka ʻōlelo i kēia manawa no ka mālama mua ʻana iā RA me nā lāʻau antirheumatic (DMARDs) e hoʻololi nei i ka maʻi. ʻO kekahi o kēia mau lāʻau lapaʻau he methotrexate. E nānā pehea e hana ai kēia lāʻau, e like me ka hopena o ka mālama ʻana iā RA.

Mālama iā RA me ka methotrexate

ʻO Methotrexate kahi ʻano DMARD. ʻO nā DMARD kahi papa o nā lāʻau i hoʻohana pinepine ʻia i nā wā mua o RA. Ua hana kikoʻī ʻia kekahi mau lāʻau i ka papa DMARD no ka mālama ʻana iā RA, akā ua hoʻomohala ʻia ka methotrexate no kekahi kumu ʻokoʻa. Ua hana mua ʻia ia e mālama i ka maʻi ʻaʻai, akā ua ʻike ʻia e hana pū kekahi me RA. Kūʻai aku ia ma lalo o nā inoa inoa ʻo Rheumatrex a me Trexall. Hele mai ia ma kahi papa waha a me kahi hopena no ka pahu kui.

Hana ka Methotrexate a me nā DMARD ʻē aʻe e hōʻemi i ka lī. Hana lākou i kēia ma ke kāohi ʻana i kāu ʻōnaehana pale. Aia nā pilikia e pili pū me ka mālama ʻana i kāu ʻōnaehana pale maʻi i ka nānā ʻana i kēia ala, akā, me ka hoʻonui ʻia o ka makaʻu o nā maʻi.

ʻOiai hele mai ka methotrexate me ka manawa o nā hopena ʻaoʻao, hāʻawi ia i nā keu maikaʻi loa no ka poʻe me RA. Hiki i nā DMARD ke pale aku i ka hōʻino pū inā hoʻohana mua ʻoe ia mau mea ma hope o ka hōʻike mua ʻia ʻana o kāu mau hōʻailona RA. Hiki iā lākou ke hoʻolohi hou i ka hōʻino hui a hoʻopau i nā hōʻailona o RA. Manaʻo ka hapa nui o nā kauka a me ka poʻe me RA nā keu pono o kēia lāʻau.

ʻO ka Methotrexate kahi lāʻau lōʻihi lōʻihi ke hoʻohana ʻia no RA. Lawe ka hapanui o ka poʻe iā ia a hiki i ka wā ʻaʻole hana hou ia no lākou a i ʻole hiki iā lākou ke hoʻomanawanui i nā hopena ma kā lākou ʻōnaehana pale maʻi.

Ka hoʻokō ʻana

ʻO Methotrexate ka lāʻau no ka hapa nui o nā kauka e mālama nei iā RA. Loaʻa kēia i ka maikaʻi o ka hana. Wahi a Johns Hopkins, lawe ka hapanui o ka poʻe i ka methotrexate no kahi manawa lōʻihi i hoʻohālikelike ʻia me nā DMARD ʻē aʻe a i ʻelima mau makahiki. Hōʻike kēia i ka maikaʻi o ka mālama ʻana i ke ʻano a me ka maikaʻi o ka hoʻomanawanui ʻana o ka poʻe.

Hōʻike nā helu e kōkua ka methotrexate i ka hapa nui o ka poʻe me RA. Wahi a ka National Rheumatoid Arthritis Society, ʻoi aku ma mua o ka hapalua o ka poʻe e lawe ana iā lākou e ʻike i kahi 50 pakeneka e hoʻomaikaʻi ai i ka holo o ko lākou maʻi. A ʻoi aku ma mua o ka hapakolu o ka poʻe i ʻike i ka hoʻonui ʻana he 70 pākēneka. ʻAʻole ʻike ka poʻe āpau i ke kōkua me ka methotrexate, akā ʻoi aku ka maikaʻi o ka hana no nā poʻe he nui ma mua o nā DMARD ʻē aʻe.

Inā ʻaʻole i hana ka lapaʻau methotrexate no kāu RA i ka manawa mua, aia ka manaolana. A

I ka hui pū me nā lāʻau ʻē aʻe

Hoʻohana pinepine ʻia ʻo Methotrexate me nā DMARD ʻē aʻe a i ʻole nā ​​lāʻau ʻē aʻe no ka ʻeha a me ka mumū. Ua hōʻike ʻia he hoa maikaʻi loa. Hoʻohui kekahi o nā DMARD ʻelua a ʻoi-mau me ka methotrexate ma ke ʻano he mea hana i ʻoi aku ka maikaʻi ma mua o ka methotrexate wale nō. E hoʻomanaʻo i kēia inā ʻaʻole ʻoe e pane iā methotrexate e ia iho. Hiki iā ʻoe ke kamaʻilio me kāu kauka e pili ana i kahi therapy hoʻohui.

Nā hopena ʻaoʻao o ka methotrexate

Ma waho aʻe o ka hana maoli no nā poʻe he nui, makemake nā kauka e hoʻohana i ka methotrexate no ka mea maʻamau ʻole nā ​​hopena ʻino. Akā e like me nā lāʻau āpau, hiki i ka methotrexate ke kumu i nā hopena ʻaoʻao. Hiki i nā hopena ʻaoʻao maʻamau ke hoʻopili:

• hoʻohuhū ʻōpū
• luhi
• lauoho lahilahi

Hiki paha iā ʻoe ke hoʻohaʻahaʻa i kou makaʻi i kēia mau hopena inā ʻoe e lawe i kahi waihona folic acid. E noi i kāu kauka inā kūpono kēia mea kōkua nou.

E kamaʻilio me kāu kauka

Inā loaʻa iā RA, e kamaʻilio me kāu kauka e pili ana i ka methotrexate. Ua hōʻike maikaʻi ʻia kēia lāʻau me ka hana ʻole i nā hopena ʻaoʻao he nui no ka poʻe me RA. Inā hana ʻole ka methotrexate e mālama i kāu RA mau hōʻailona, ​​hāʻawi paha kāu kauka iā ʻoe i kahi lāʻau kiʻekiʻe a i ʻole kahi lāʻau e lawe pū me ka methotrexate.