Papa Inoa Laau Lapaau o Rheumatoid

Anter

• Nā DMARD a me nā meaolaola
• Pili ʻo Janus i nā mea kūpina kinase
• ʻO Acetaminophen
• Nā lāʻau anti-inflammatory nonsteroidal (NSAIDs)
• Ibuprofen (Advil, Motrin IB, Nuprin)
• Naproxen sodium (Aleve)
• ʻO Aspirin (Bayer, Bufferin, St. Joseph)
• Nā NSAID kuhikuhi
• ʻO Diclofenac / misoprostol (Arthrotec)
• Topsa capsaicin (Capsin, Zostrix, Dolorac)
• Diclofenac sodium topical gel (Voltaren 1%)
• ʻO Diclofenac sodium topical solution (Pennsaid 2%)
• Nā lāʻau ʻeha opioid
• Corticosteroids
• Nā Immunosuppressants
• Lawe aku

Hōʻike Overview

ʻO Rheumatoid arthritis (RA) ka lua o nā ʻano maʻamau o ka maʻi kōwī, e pā ana ma kahi o 1.5 miliona mau ʻAmelika. He maʻi hōʻeha ia i hopena ʻia e kahi ʻano autoimmune. Kū ka maʻi i ka wā e hoʻouka ai kou kino i kāna mau hui pono olakino ponoʻī. ʻO kēia ka hopena i ka ʻulaʻula, ka mumū, a me ka ʻeha.

ʻO ka pahuhopu nui o nā lāʻau RA ke pale i ka mumū. Kōkua kēia i ka pale ʻana i ka hōʻino pū. E heluhelu e aʻo e pili ana i nā koho lapaʻau he nui no RA.

Nā DMARD a me nā meaolaola

Hoʻohana ʻia nā lāʻau antirheumatic (DMARD) e hoʻoliʻiliʻi ai i ka mumū. ʻAʻole like me nā lāʻau ʻē aʻe e hōʻoluʻolu iki i ka ʻeha a me ka mumū, hiki i nā DMARD ke hoʻolohi i ka holomua o RA. ʻO kēia ka loaʻa ʻana iā ʻoe o nā ʻōuli liʻiliʻi a me nā hōʻemi liʻiliʻi o ka manawa.

ʻO nā DMARD maʻamau e hoʻohana ʻia e mālama iā RA e komo pū:

• hydroxychloroquine (Plaquenil)
• leflunomide (Arava)
• methotrexate (Trexall)
• sulfasalazine (Azulfidine)
• minocycline (Minocin)

ʻO nā biologics nā lāʻau hoʻōki. Hana lākou ma ka pale ʻana i nā ala uila kikoʻī i hana ʻia e nā hunaola pale. Hoʻoiho kēia i ka mumū ma muli o RA. Kau kauka i nā biologics ke lawa ʻole nā ​​DMARD wale nō e mālama i nā hōʻailona RA. ʻAʻole koi ʻia nā meaolaolaola no nā poʻe me nā ʻōnaehana pale i hoʻohuli ʻia a i ʻole kahi maʻi. ʻO kēia no ka mea hiki iā lākou ke hāpai i kāu makaʻu i nā maʻi koʻikoʻi.

ʻO nā biologics maʻamau ʻo:

• abatacept (Orencia)
• rituximab (Rituxan)
• tocilizumab (Actemra)
• anakinra (Kineret)
• adalimumab (Humira)
• etanercept (Enbrel)
• infliximab (Remicade)
• certolizumab pegol (Cimzia)
• golimumab (Simponi)

Pili ʻo Janus i nā mea kūpina kinase

Kauoha paha kāu kauka i kēia mau lāʻau inā ʻaʻole holo pono nā DMARD a i ʻole nā ​​meaolaola iā ʻoe. Hoʻopili kēia mau lāʻau i nā genes a me ka hana o nā hunaola pale i loko o ke kino. Kōkua lākou i ka pale ʻana i ka mumū a hoʻōki i ka hōʻino ʻana o nā hono a me nā ʻaʻa.

Hoʻopili pū ʻo Janus i nā mea kāohi i nā kinase:

• tofacitinib (Xeljanz, Xeljanz XR)
• baricitinib

ʻO Baricitinib kahi lāʻau hou e hoʻāʻo ʻia. Hōʻike nā noiʻi e hana ia no nā poʻe i loaʻa ʻole ka kūleʻa me DMARD.

ʻO nā hopena ʻaoʻao maʻamau o kēia mau lāʻau e:

• ʻeha poʻo
• nā maʻi hanu o luna, e like me nā maʻi sinus a i ʻole ke anuanu maʻamau
• ihu huikau
• ihu ihope
• eha ka 'ā'ī
• pāhoehoe

ʻO Acetaminophen

Loaʻa ka Acetaminophen ma luna o ka counter (OTC) me ka ʻole o ka palapala mai kāu kauka. Hele mai ia ma ke ʻano he lāʻau lapaʻau waha a me kahi ʻaoʻao suppository. ʻOi aku ka maikaʻi o nā lāʻau ʻē aʻe i ka hōʻemi ʻana i ka lī a me ka mālama ʻana i ka ʻeha ma RA. ʻO kēia no ka mea hiki i ka acetaminophen ke mālama i ka ʻeha me ka ʻeha kaulike, akā ʻaʻohe ona hana anti-inflammatory. ʻO ke kumu ʻaʻole holo pono kēia e mālama iā RA.

Lawe kēia lāʻau i ka makaʻu i nā pilikia koʻikoʻi o ke ake, e like me ka maikaʻi ʻole o ke ake. E lawe wale ʻoe i hoʻokahi lāʻau i loaʻa ka acetaminophen i kēlā me kēia manawa.

Nā lāʻau anti-inflammatory nonsteroidal (NSAIDs)

ʻO nā NSAID kekahi o nā lāʻau RA i hoʻohana pinepine ʻia. ʻAʻole like me nā mea hōʻeha ʻeha ʻē aʻe, ʻoi aku ka maikaʻi o nā NSAID i ka mālama ʻana i nā hōʻailona o RA. ʻO kēia no ka mea pale lākou i ka mumū.

Hoʻohana kekahi poʻe iā OTC NSAIDs. Eia nō naʻe, loaʻa nā NSAID ikaika me kahi kuhikuhi.

Nā hopena ʻē aʻe o nā NSAID me:

• huhū o ka ʻōpū
• ulcer
• ka hoʻoneʻe a i ʻole ke ahi ʻana i kahi puka ma o kou ʻōpū a i ʻole nā ​​ʻōpū
• kahe ʻana o ka ʻōpū
• hōʻino kīhāpai

I nā hihia maʻamau, hiki i kēia mau hopena i ka make (kumu make). Inā hoʻohana ʻoe i nā NSAID no kekahi manawa lōʻihi, e nānā kāu kauka i kāu hana hakuʻala. ʻOi paha kēia inā loaʻa ʻoe i ka maʻi puʻupaʻa.

Ibuprofen (Advil, Motrin IB, Nuprin)

ʻO ka'TCTC ibuprofen ka NSAID maʻamau. Inā ʻaʻole i aʻo ʻia e kāu kauka, ʻaʻole pono ʻoe e hoʻohana i ka ibuprofen ma mua o kekahi mau lā i ka manawa. ʻO ka lawe ʻana i kēia lāʻau i lōʻihi loa ke kumu e kahe ai ka ʻōpū. ʻOi aku ka nui o kēia pilikia i ka poʻe ʻelemākule.

Loaʻa ʻo Ibuprofen i nā ikaika i kuhikuhi ʻia pū kekahi. I nā mana i kuhikuhi ʻia, ʻoi aku ka kiʻekiʻe o ke ana. Hoʻohui pū ʻia ʻo Ibuprofen me kekahi ʻano lāʻau ʻeha i kapa ʻia ʻo opioids. ʻO nā laʻana o kēia mau lāʻau hoʻohui e like me:

• ibuprofen / hydrocodone (Vicoprofen)
• ibuprofen / oxycodone (Combunox)

Naproxen sodium (Aleve)

ʻO Naproxen sodium kahi OTC NSAID. Hoʻohana pinepine ʻia ia ma ke ʻano he koho i ka ibuprofen. ʻO kēia no ka mea he kumu ia e hōʻemi iki ai i nā hopena. Hāʻawi nā mana kuhikuhi o kēia lāʻau i nā lāʻau ikaika.

ʻO Aspirin (Bayer, Bufferin, St. Joseph)

ʻO Aspirin kahi mea hōʻeha ʻeha waha. Hoʻohana ia e mālama i ka ʻeha mālie, ke kuni, a me ka mumū. Hiki nō ke hoʻohana e pale aku i ka puʻuwai puʻuwai a me ka hahau ʻana.

Nā NSAID kuhikuhi

Ke hōʻoluʻolu ʻole ʻo OTC NSAID i kāu mau hōʻailona RA, hiki i kāu kauka ke kuhikuhi i kahi palapala kauoha NSAID. ʻO kēia nā lāʻau lapaʻau waha. ʻO nā koho maʻamau e hoʻopili ʻia:

• celecoxib (Celebrex)
• ibuprofen (kuhikuhi-ikaika)
• nabumetone (Relafen)
• naproxen sodium (Anaprox)
• naproxen (Naprosyn)
• piroxicam (Feldene)

ʻO nā NSAID ʻē aʻe:

• diclofenac (Voltaren, Diclofenac Sodium XR, Cataflam, Cambia)
• diflunisal
• indomethacin (Indocin)
• ketoprofen (Orudis, Ketoprofen ER, Oruvail, Actron)
• etodolac (Lodine)
• fenoprofen (Nalfon)
• flurbiprofen
• ketorolac (Toradol)
• meclofenamate
• mefenamic acid (Ponstel)
• meloxicam (Mobic)
• oxaprozin (Daypro)
• sulindac (Clinoril)
• salsalate (Disalcid, Amigesic, Marthritic, Salflex, Mono-Gesic, Anaflex, Salsitab)
• tolmetin (Tolectin)

ʻO Diclofenac / misoprostol (Arthrotec)

ʻO Diclofenac / misoprostol (Arthrotec) kahi lāʻau waha e hoʻohui i ka diclofenac NSAID me misoprostol. Hiki i nā NSAID ke hana i nā maʻi maʻi ʻōpū. Kōkua kēia lāʻau i ka pale aku iā lākou.

Topsa capsaicin (Capsin, Zostrix, Dolorac)

Hiki iā Capsaicin topical OTC cream ke hoʻokuʻu i ka ʻeha mehana i hoʻokumu ʻia e RA. Hoʻopili ʻoe i kēia kalima ma nā wahi ʻeha ma kou kino.

Diclofenac sodium topical gel (Voltaren 1%)

ʻO Voltaren gel 1% kahi NSAID no ka hoʻohana kumuhana. Kuhi kēia ʻōpala iā ʻoe i kou ʻili. Ua ʻae ʻia e mālama i ka ʻeha pū, e like me kou mau lima a me kou mau kuli.

Hoʻokumu kēia lāʻau i nā hopena ʻē aʻe i nā NSAID waha. Eia naʻe, ma kahi o 4 ka pākēneka o kēia lāʻau i komo i loko o kou kino. ʻO kēia ka mea e liʻiliʻi paha ʻoe i nā hopena ʻaoʻao.

ʻO Diclofenac sodium topical solution (Pennsaid 2%)

ʻO Diclofenac sodium (Pennsaid 2%) kahi hopena kumuhana i hoʻohana ʻia no ka ʻeha o ke kuli. Hoʻopili ʻoe iā ia ma kou kuli e hoʻomaha ai ka ʻeha.

Nā lāʻau ʻeha opioid

ʻO nā lāʻau opioids nā lāʻau ʻehaʻeha loa ma ka mākeke. Loaʻa wale lākou ma ke ʻano he lāʻau lapaʻau. Hele mai lākou i loko o ka waha a me nā ʻano hana hoʻoheheʻe. Hoʻohana wale ʻia nā Opioids i ka mālama RA no ka poʻe me ka RA koʻikoʻi e ʻeha nui nei. Hiki i kēia mau lāʻau ke hana maʻa. Inā hāʻawi kāu kauka iā ʻoe i ka lāʻau opioid, e nānā pono lākou iā ʻoe.

Corticosteroids

Kapa ʻia ʻo Corticosteroids he steroid. Hele mai lākou ma ke ʻano he lāʻau lapaʻau waha a hoʻopiki. Hiki i kēia mau lāʻau ke kōkua i ka hōʻemi ʻana i ka mumū ma RA. Hiki iā lākou ke kōkua i ka hōʻemi ʻana i ka ʻeha a me nā pōʻino i hoʻokumu ʻia e ka mumū. ʻAʻole koi ʻia kēia mau lāʻau no ka hoʻohana wā lōʻihi.

Hiki i nā hopena ʻaoʻao ke hoʻopili i:

• kō kō kiʻekiʻe
• ʻōpū o ka ʻōpū
• kahe koko kiʻekiʻe
• nā hopena hopena o ka naʻau, e like me ka huhū a me ka hauʻoli
• cataract, a i ʻole ke ao ʻana o nā aniani i kou maka
• ʻosteoporosis

Hoʻohana ʻia nā Steroids no RA me:

• betamethasone
• prednisone (Deltasone, Sterapred, Liquid Pred)
• dexamethasone (Dexpak Taperpak, Decadron, Hexadrol)
• cortisone
• hydrocortisone (Cortef, A-Hydrocort)
• methylprednisolone (Medrol, Methacort, Depopred, Predacorten)
• prednisolone

Nā Immunosuppressants

Kūʻē kēia mau lāʻau i ka hōʻino o nā maʻi autoimmune e like me RA. Eia nō naʻe, hiki i kēia mau lāʻau ke hoʻohālikelike iā ʻoe i ka maʻi a me ka maʻi. Inā hāʻawi kāu kauka iā ʻoe i kekahi o kēia mau lāʻau, e nānā pono lākou iā ʻoe i ka wā o ka lāʻau.

Hele mai kēia mau lāʻau i loko o ka waha a me nā ʻano o ka injection. Pākuʻi ʻia lākou:

• cyclophosphamide (Cytoxan)
• cyclosporine (Gengraf, Neoral, Sandimmune)
• azathioprine (Azasan, Imuran)
• hydroxychloroquine (Plaquenil)

Lawe aku

Hana pū me kāu kauka e ʻike i ka hoʻomaʻamaʻa RA e kūpono loa iā ʻoe. Me nā koho he nui i loaʻa, ʻike paha ʻoe a me kāu kauka i kahi e hoʻomaʻamaʻa ai i kāu mau hōʻailona RA a hoʻomaikaʻi i kou ola.