ʻO nā mea āpau āu e ʻike ai e pili ana iā Johnson & Johnson's COVID-19 Vaccine

Anter

• Pehea ka hana ʻana o ka lāʻau lapaʻau ʻo Johnson & Johnson COVID-19?
• Pehea ka maikaʻi o ka lāʻau lapaʻau Johnson & Johnson COVID-19?
• ʻIkepili o ka maʻi a me ka make ʻana o COVID-19
• ʻO COVID-19 ʻano
• ʻEhia ka nui o ka maʻi o Johnson & Johnson COVID-19 āu e pono ai?
• Pehea ka hopena a Johnson & Johnson i ka hoʻoili COVID-19?
• Nānā no

Ma Pepeluali 26, ua hoʻoholo lōkahi ke kōmike aʻoaʻo aʻoaʻo a kā FDA e hōʻoia iā Johnson & Johnson's COVID-19 vaccine for emergency use. ʻO ia ke ʻano o ke kano - e koi ana i hoʻokahi wale nō maʻi - hiki ke mākaukau no ka hoʻohana ʻana ma US ma ka hopena o Malaki, e like me ka Center for Infectious Disease Research and Policy (CIDRAP).

Akā, pehea ka maikaʻi o ka lāʻau lapaʻau ʻo Johnson & Johnson's COVID-19? A pehea ia e hoʻohālikelike ai i nā lāʻau lapaʻau COVID-19 ʻē aʻe mai Pfizer a me Moderna? Eia ka mea e pono ai ʻoe e ʻike.

Pehea ka hana ʻana o ka lāʻau lapaʻau ʻo Johnson & Johnson COVID-19?

Inā kamaʻāina ʻoe i nā lāʻau hoʻomaʻamaʻa COVID-19 i hana ʻia e Pfizer a me Moderna, a laila maopopo paha iā ʻolua he huina mRNA lāua ʻelua. ʻO ia ka hana a ka hoʻopili ʻana i kahi ʻāpana o ka protein spike o ka SARS-CoV-2 (ʻo ka ʻāpana o ka maʻi e hoʻopili iā ia iho i nā hunaola i kou kino) a me ka hoʻohana ʻana i kēlā mau ʻāpana i hoʻopili ʻia e hoʻomaka i kahi pane pale mai kou kino i hana ia nā antibodies e kūʻē i ka maʻi maʻi. (E nānā: Pehea ka maikaʻi o ka Vaccine COVID-19?)

ʻOkoʻa iki kā Johnson & Johnson vaccine. No ka mea hoʻokahi, ʻaʻole ia he kano mRNA. He lāʻau lapaʻau adenovector ia, ʻo ia hoʻi hoʻohana ia i kahi virus i hoʻopau ʻole ʻia (i kēia hihia, adenovirus, ke kumu o ke anuanu maʻamau) ma ke ʻano he vector e lawe i nā proteins (i kēia hihia, ka pūnana spike mai SARS-CoV-2) e makemake ai kou kino ʻike e like me ka hoʻoweliweli a hana i nā mea ʻino e kūʻē iā, wahi a Brittany Busse, MD, ka luna hoʻomalu olakino pili ma WorkCare.

I kēia manawa, e noʻonoʻo paha ʻoe inā ʻo ka hoʻokomo ʻana i kahi "virus inactivated" i loko o kou kino e maʻi me ka ʻike ʻole, akā ʻaʻole. "ʻAʻole hiki i kahi maʻi hoʻomaʻemaʻe hana hou ke hoʻohālikelike a hāʻawi iā ʻoe i maʻi," wahi a Abisola Olulade, M.D., he kauka lāʻau hōʻoia ʻohana i hōʻoia ʻia e ka papa ma Sharp Rees-Stealy Medical Group. Akā, ʻo ka adenovirus i loko o Johnson & Johnson's COVID-19 e lawelawe wale nei ma ke ʻano he mea lawe (a i ʻole "vector") o ka gen protein spike o SARS-CoV-2 i loko o kāu mau cell, e hana ai nā cell i nā kope o kēlā ʻano, wehewehe ʻo ia. E noʻonoʻo i ka spike protein gene e like me ke ʻano o nā ʻōlelo aʻo no ke ʻano e hiki ai i kou kino ke hakakā iā SARS-CoV-2, wahi a Kauka Olulade. "Hiki ke ʻike ʻia kēia mau protein spike e kāu ʻōnaehana paleʻea a hoʻolilo iā ʻoe e hana i nā mea pale e pale aku ai iā COVID," wehewehe ʻo ia. (FYI: Hana like ka pana ʻana i ka maʻi maʻi.)

ʻOiai ʻokoʻa kēia ʻenehana lapaʻau mai ka Pfizer a me Moderna, ʻaʻole ia he manaʻo noʻonoʻo. ʻO ka lāʻau lapaʻau COVID ʻo Oxford a me AstraZeneca - i ʻae ʻia no ka hoʻohana ʻana i ka EU a me ke UK i Ianuali (ke kali nei ka FDA i ka ʻikepili mai ka hoʻokolohua hoʻokolohua hoʻokolohua a AstraZeneca ma mua o ka noʻonoʻo ʻana i ka ʻae ʻia e U.S., ka Nu Ioka Manawa hōʻike) - hoʻohana i ka ʻenehana adenovirus like. Ua hoʻohana pū ʻo Johnson & Johnson i ka ʻenehana no ka hana ʻana i kāna kano Ebola, i hōʻike ʻia he palekana a maikaʻi hoʻi i ka hana ʻana i kahi pane pale i loko o ke kino.

Pehea ka maikaʻi o ka lāʻau lapaʻau Johnson & Johnson COVID-19?

I loko o kahi hoʻokolohua lapaʻau nui o kahi kokoke i 44,000 poʻe, ua hōʻike ʻia ʻo Johnson & Johnson's COVID-19 he 66 pākēneka ka hopena holoʻokoʻa i ka pale ʻana i ka haʻahaʻa (i wehewehe ʻia he hoʻokahi a ʻoi aku paha nā hōʻailona COVID-19) i ka COVID-19 koʻikoʻi (i hōʻike ʻia e ke komo ʻana i kahi ICU, ka hanu ʻana, a i ʻole ka hemahema o ke kino, ma waena o nā kumu ʻē aʻe) 28 mau lā ma hope o ka hoʻopaʻa ʻana, e like me ka hoʻokuʻu ʻana mai ka hui. (E waiho ʻia ka ʻikepili i kahi puke pai i nānā ʻia e nā hoa i nā pule e hiki mai ana, "wahi a ka nūpepa.)

Ua hōʻike pū ʻo Johnson & Johnson ʻo ka pae o kāna kano o ka pale ʻana i ka maʻi maʻamau i ka COVID he 72 pākēneka ma US, 66 pākēneka ma Latin America, a me 57 pākēneka ma ʻApelika Hema (ʻo ia hoʻi, i hui pū ʻia, hāʻawi iā ʻoe i ka nui o 66 pakeneka efficacy rate) . Inā he mea liʻiliʻi kēia mau helu, pono e hoʻomaopopo ʻia, ma ka hoʻohālikelike ʻana, ʻo 40 a 60 paha pākēneka wale nō ke kī ʻana i ka maʻi flu i ka pale ʻana i ke kino mai ka maʻi palū, akā he hana nui nō ia i ka hōʻemi ʻana i nā haukapila a me nā make e pili ana i ka maʻi flu. Kauka Olulade. (Pili: Hiki i ka Flu Shot ke pale iā ʻoe mai Coronavirus?)

ʻIkepili o ka maʻi a me ka make ʻana o COVID-19

I ka mua, Johnson a Johnson's vaccine efficacy rate of 66 pakeneka paha he ʻano haʻahaʻa paha, keu hoʻi ke hoʻohālikelike ʻia ia i nā helu pono mai Moderna (94.5 pakeneka maikaʻi) a me Pfizer ("ʻoi aku ma mua o 90 pākēnika maikaʻi," e like me ka ʻoihana). Akā inā ʻoe e ʻeli hohonu, ʻike ʻo Johnson & Johnson hana hōʻike i nā hopena hoʻohiki hou aʻe, i ka wā e hiki mai ana i nā hihia koʻikoʻi COVID-19.

Ma nā wahi āpau, ua loaʻa ka lāʻau lapaʻau 85 pakeneka pono i ka pale ʻana i ka COVID-19 koʻikoʻi, e like me ka hoʻokuʻu ʻana o Johnson & Johnson. I ka ʻoiaʻiʻo, ua hōʻike ka ʻoihana ua hōʻike ʻia kāna lāʻau lapaʻau "pale piha i ka haukapila pili i ka COVID a me ka make" 28 mau lā ma hope o ka lāʻau ʻana, "me ka ʻole o nā hihia i hōʻike ʻia" o ka hoʻokipa ʻia ʻana e pili ana i ka COVID a i ʻole ka make i waena o ka poʻe i loaʻa ka lāʻau lapaʻau a Johnson & Johnson.

I ka ʻōlelo o nā hopena ʻaoʻao, ua ʻōlelo ʻo Johnson & Johnson ʻo kāna kano COVID "ua ʻae maikaʻi ʻia" ma waena o nā poʻe āpau i ka hoʻokolokolo. Hōʻike ka ʻikepili mua o ka ʻoihana e hiki i ka lāʻau lapaʻau ke hoʻoulu i nā "hopena ʻaoʻao haʻahaʻa a me ka haʻahaʻa e pili pū ana me nā lāʻau lapaʻau," e like me ka luhi, ke poʻo, ka ʻeha o ka ʻiʻo, a me ka ʻeha o ka wahi.

ʻO COVID-19 ʻano

ʻAʻole like me nā haʻawina a Pfizer a me Moderna, ʻo ka hoʻāʻo ʻana o ka maʻi maʻi a Johnson & Johnson e loaʻa nā hopena ma nā wahi he nui - me nā mea i ʻike hou i ka piʻi ʻana o nā hihia COVID i hoʻokumu ʻia e nā ʻano like ʻole o ka maʻi. "ʻAʻole paha i mana nui ʻia [keia mau ʻano like ʻole] i ka manawa i aʻo ʻia ai nā lāʻau lapaʻau mua," wahi a Kauka Olulade. ʻOiaʻiʻo, ke nānā nei nā mea noiʻi i kēia manawa pehea ka maikaʻi pau loa Hiki i nā lāʻau lapaʻau COVID-19 ke pale i ke kino mai nā ʻano like ʻole COVID-19. I kēia manawa, ʻōlelo ʻo Dr. Busse ʻo ka ʻokoʻa UK "ʻaʻole paha he hopohopo no nā kano COVID." Eia naʻe, hoʻohui ʻo ia, ma laila ʻo ia manaʻo ʻia e hiki i nā ʻano like ʻole o COVID mai ʻApelika Hema a me Brazil ke "hoʻololi i ke ʻano o ka hui ʻana o nā antibodies me ka maʻi maʻi" a hiki ke hoʻolilo i kēlā mau antibodies pale "ʻoi aku ka maikaʻi." (E pili ana: No ke aha e laha wikiwiki nei nā ʻano hou COVID-19?)

ʻLelo ʻia, ʻoiai ʻaʻole hiki i ka lāʻau āpau ke pale aku i ka maʻi COVID-19, akā he mea kōkua ia i ka poʻe e hōʻalo i nā maʻi maikaʻi loa o ka maʻi. "ʻO ia hoʻi, hiki iā ia ke hoʻemi i ka ukana ma luna o kā mākou ʻōnaehana mālama ola kino a hoʻokokoke iā mākou i kēlā kukui ma ka hope o ke alahele," wahi a Kauka Olulade.

"He mea nui nō hoʻi e hoʻomanaʻo i ka hiki koke iā mākou ke loaʻa i ka poʻe i ka pale ʻana, ʻoi aku ka liʻiliʻi o nā hoʻololi ʻana o ka maʻi e hoʻololi a hana hou," wahi a Kauka Olulade. "ʻO ia ke kumu e pono ai mākou e kiʻi i nā kānaka āpau i ka wī ʻia."

ʻEhia ka nui o ka maʻi o Johnson & Johnson COVID-19 āu e pono ai?

Ma waho aʻe o ka pono o ka lāʻau lapaʻau ponoʻī, ʻōlelo ka poʻe loea ʻo Johnson & Johnson's COVID ka hoʻohiki ʻana no ka mea e koi wale ana i hoʻokahi pana, ʻoiai ʻo Pfizer's a me Moderna's kano e koi i ʻelua mau pana i hoʻokaʻawale ʻia e ʻelua pule.

"He mea hoʻololi pāʻani paha kēia," wahi a Kauka Olulade. "ʻIke mākou i kekahi mau maʻi, ʻaʻole naʻe e hoʻi hou mai no kā lākou maʻi lua," no laila hiki i kēia ala hoʻokahi-a-hana ke unuhi i nā lāʻau āpau.

ʻO kahi pōmaikaʻi nui ʻē aʻe i ka kano COVID a Johnson & Johnson? ʻOi aku ka maʻalahi o ka mālama ʻana i nā mahele ma mua o ka mālama ʻana o Pfizer's a me Moderna vaccine, mahalo i ka hoʻohana ʻana o J & J i ka ʻenehana vaccine adenovector. "ʻO ka Adenovirus [ma ka maʻi maʻi a Johnson & Johnson] ʻoi aku ka maʻalahi a ʻaʻole like me ka palupalu [e like me ka mRNA i nā lāʻau lapaʻau a Pfizer a me Moderna]," ʻo ia ka mea e koi ai i ka mālama ʻana i nā mahana anuanu, wehewehe ʻo Kauka Busse. "Paʻa ka maʻi maʻi Johnson & Johnson i loko o ka friji a hiki i ʻekolu mahina, e maʻalahi ai ka moku a hāʻawi aku i ka poʻe e pono ai."

Pehea ka hopena a Johnson & Johnson i ka hoʻoili COVID-19?

"He kakahiaka nui loa ia e haʻi aku ai," wahi a Prabhjot Singh, M.D., Ph.D., ka luna lapaʻau nui a me ka ʻepekema ʻōlelo aʻoaʻo o CV19 CheckUp, kahi mea hana pūnaewele e kōkua i ka loiloi i kāu mau pilikia COVID-19. Pela no pau loa o nā lāʻau āpau COVID-19 a mākou i ʻike ai a hiki i kēia manawa ʻo BTW, ʻaʻole ʻo Johnson & Johnson wale nō, e ʻōlelo ana ʻo Kauka Singh. "ʻO nā haʻawina mua e hōʻike ana e emi ka hopena o ka lawe ʻana ma hope o ka hoʻopaʻa ʻia ʻana, akā pono ka pane paʻa i kahi noiʻi maʻamau," wehewehe ʻo ia.

No ka mea ʻaʻole ʻike ʻia nā hopena o nā kano i ka hoʻoili ʻana o COVID, ʻoi aku ka nui o ka mea nui e hoʻomau i ka hoʻohana ʻana i nā masks a mālama i kou mamao mai nā poʻe ma waho o kou home, wahi a Kauka Olulade. (E kali, pono ʻoe e pālua i ka pale ʻana e pale aku iā COVID-19?)

Laina lalo: ʻO nā mea a pau ʻO kēia mau lāʻau lapaʻau e like me ka hāʻawi ʻana i ka pale koʻikoʻi mai COVID-19, ʻo ia ka maikaʻi. Eia nō naʻe, "ʻaʻole he laikini e hoʻokuʻu i kou kiaʻi," wahi a Kauka Olulade. "Pono mākou e noʻonoʻo me ke aloha ʻole e pili ana i ke olakino a me ke olakino o nā poʻe ʻē aʻe i hana ʻole i ka lāʻau āpau a ʻaʻohe paha palekana mai COVID."

Pololei ka ʻike ma kēia moʻolelo e like me ka manawa paʻi. Ke hoʻomau nei nā mea hou e pili ana i ka coronavirus COVID-19, ua loli paha kekahi mau ʻike a me nā manaʻo i kēia moʻolelo mai ka hoʻolaha mua ʻana. Paipai mākou iā ʻoe e nānā pinepine me nā kumuwaiwai e like me ka CDC, ka WHO, a me kāu keʻena olakino kūloko kūloko no ka ʻikepili a me nā ʻōlelo aʻoaʻo hou loa.

Nānā no