He aha ka Malignant Hyperthermia a pehea e hana ai ka lāʻau?

Anter

• Nā kumu kūpono
• He aha nā hōʻailona
• Pehea e hana ai i ka lāʻau

ʻO ka hyperthermia malignant kahi o ka hoʻonui palena ʻole o ka mahana o ke kino, i ʻoi aku i ka hiki i ke kino ke lilo i ka wela, me ka loli ʻole o ka hoʻoponopono ʻana o ke kikowaena thermoregulatory hypothalamic, ʻo ia ka mea maʻamau i nā hanana o ke kuni.

Hiki ke hana i ka hyperthermia malignant i ka poʻe i loaʻa ka pono ʻole i nā mākala iwi a ʻike ʻia i nā anesthetics inhaled, e like me ka halothane a i ʻole enflurane, no ka laʻana a ma hope hoʻi o ka hōʻike ʻana i kahi mea hoʻomaha muso i kapa ʻia ʻo succinylcholine.

Hoʻomaʻamaʻa ʻia ke anuanu o ke kino a me ka lawelawe ʻana i nā lāʻau i loko o ka aa, kahi e pono ai ke hana e like me ka hiki, no ka mea hiki ke make ka hyperthermia malignant.

Nā kumu kūpono

Hoʻokumu ʻia ka hyperthermia malignant e kahi anomaly hoʻoilina i kū i ka sarcoplasmic retikulum o nā mākala iwi, kahi e hoʻonui ai i ka nui o ka calcium i loko o nā hunaola, i ka pane ʻana i ka lawelawe ʻana o nā anesthetics inhaled, e like me halothane a i ʻole enflurane, no ka laʻana ma muli o ka hōʻike ʻana i ka succinylcholine muscle relaxant.

E ʻike pehea e holo ai ka anesthesia ākea a me nā mea e ʻike ʻia ai ka pilikia.

ʻO kēia kiʻekiʻe o ka calcium i loko o ka mākala iwi e alakaʻi ai i ka hoʻokumu ʻia ʻana o kahi kuʻikahi maso i hoʻonui ʻia, e hoʻonui koke ana i ka mahana.

He aha nā hōʻailona

Hana pinepine ʻia nā ʻōuli o ka hyperthermia malignant i ka wā o ke anesthesia a kiʻekiʻe ke ana wela, hoʻonui ka nui o ka naʻau a me ka metabolism i nā mākala, ʻoʻoleʻa ka ʻeha a me ka ʻeha, acidosis a me ka paʻa ʻole o nā mākala

Pehea e hana ai i ka lāʻau

Pono e mālama koke ʻia ka hyperthermia malignant ma ke kāpae ʻana i ka anesthesia a me ka lawelawe ʻana i ka dantrolene sodium vein, no kahi manawa o 24 a 48 mau hola, a hiki i ke kanaka ke hoʻohana i ka lāʻau ma ka waha, inā pono nō ia.

Ma waho aʻe o ka lawelawe ʻana o kēia lāʻau, hiki ke hoʻomaʻalili ʻia ke kino o ke kanaka me nā ʻāpana pulu, nā pā a me nā ʻauʻau hau a, inā ʻaʻole lawa kēia mau hana hoʻoluʻu kūwaho, hiki ke hoʻomaʻalili ʻia ke kino i loko e ka gastric lavage me ka serum.

I nā hihia ʻoi loa, kahi e hiki ʻole ai ke hoʻohaʻahaʻa lawa ka mahana, pono pono ka hemodialysis a i ʻole ka cardiopulmonary bypass me ke anuanu o ke koko.