Hemoglobin uila uila
Anter
- Nā pae maʻamau o nā ʻano hemoglobin
- I nā pēpē
- I nā mākua
- No ke aha e hana ai kahi electrogoresbin hemoglobin
- Kahi a pehea e lawelawe ʻia ai kahi hōʻike hemoglobin electrophoresis
- Nā pilikia o ka electrogoresis hemoglobin
- He aha ka mea e manaʻo ai ma hope o ka hoʻāʻo
He aha ka hōʻike hemoglobin electrophoresis?
ʻO kahi hoʻokolohua hemoglobin electrophoresis kahi hōʻike koko i hoʻohana ʻia e ana a ʻike i nā ʻano hemoglobin i kāu kahe koko. ʻO Hemoglobin ka protein i loko o nā hunaola ʻulaʻula i kuleana no ka lawe ʻana i ka oxygen i kāu mau aʻa a me nā meaola.
Hiki i nā hoʻololi genetic ke hana i kou kino e hana hemoglobin i hana hewa ʻia. Hiki i kēia hemoglobin keu ke kumu i ka liʻiliʻi o ka oxygen e hiki i kāu mau pūnaewele.
Aia he haneli o nā ʻano hemoglobin. Pākuʻi ʻia lākou:
- Hemoglobin F: ʻIke ʻia kēia ʻo hemoglobin fetal. ʻO ia ke ʻano i loaʻa i nā fetus e ulu nei a me nā keiki hānau hou. Ua hoʻololi ʻia me hemoglobin A ma hope koke o ka hānau ʻana.
- Hemoglobin A: ʻIke ʻia kēia he hemoglobin makua. ʻO ia ka ʻano hemoglobin maʻamau. Loaʻa ia i nā keiki olakino a me nā mākua.
- Hemoglobin C, D, E, M, a me S: He ʻano laha ʻole kēia o ka hemoglobin abnormal i hoʻokumu ʻia e nā hoʻololi kūlohelohe.
Nā pae maʻamau o nā ʻano hemoglobin
ʻAʻole hōʻike kahi hōʻike hemoglobin electrophoresis iā ʻoe e pili ana i ka nui o ka hemoglobin i kou koko - i hana ʻia i kahi helu piha o ke koko. ʻO nā pae a ka hemoglobin electrophoresis e hōʻike ai i nā pākēneka o nā ʻano hemoglobin i loaʻa i loko o kou koko. He ʻokoʻa kēia i nā pēpē a me nā mākua.
I nā pēpē
Hana ʻia ʻo Hemoglobin i hemoglobin F i nā fetus. ʻO Hemoglobin F ka mea nui o hemoglobin i nā keiki hānau hou. Hōʻole wikiwiki ia i ka manawa o kāu pēpē i hoʻokahi makahiki:
Makahiki | ʻO ka pākēneka Hemoglobin F |
hānau hou | 60 i ka 80% |
1+ makahiki | 1 i ka 2% |
I nā mākua
ʻO nā pae maʻamau o nā ʻano hemoglobin i nā mākua:
Ke ʻano o ka hemoglobin | Pakeneka |
hemoglobin A | 95% a 98% |
hemoglobin A2 | 2% a 3% |
hemoglobin F | 1% a 2% |
hemoglobin S | 0% |
hemoglobin C | 0% |
No ke aha e hana ai kahi electrogoresbin hemoglobin
Loaʻa iā ʻoe nā ʻano ʻokoʻa hemoglobin ma o ka hoʻoilina ʻana i nā mutation gen ma nā ʻāpana i kuleana no ka hana hemoglobin. Hiki i kāu kauka ke koi aku i kahi hoʻokolohua hemoglobin electrophoresis e hoʻoholo ai inā he maʻi kāu e hoʻokumu ai i ka hemoglobin maʻamau. Nā kumu e makemake ai kāu kauka iā ʻoe e hana i kahi hoʻokolohua hemoglobin electrophoresis:
1. Ma ke ʻāpana o ka nānā maʻamau: Hiki paha i kāu kauka ke hōʻoia i kou hemoglobin e ukali i kahi hōʻike koko piha i ka wā o ke kino maʻamau.
2. E ʻike pono i nā maʻi koko. E hoʻokau paha kāu kauka iā ʻoe e hana i kahi hoʻokolohua hemoglobin electrophoresis inā hōʻike ʻoe i nā hōʻailona o ka anemia. E kōkua ka hōʻike iā lākou e ʻike i kekahi ʻano hemoglobin i loko o kou koko. He hōʻailona paha kēia o nā maʻi e like me:
- anemia maʻi ʻaʻai
- thalassemia
- polycythemia vera
3. E nānā i ka mālama ʻana. Inā mālama ʻia ʻoe no kahi ʻano kumu e kumu ai i nā ʻano hemoglobin ʻole, e nānā kāu kauka i kāu mau pae o nā ʻano hemoglobin me ka electrogoresis hemoglobin.
4. No ka pale ʻana no nā kūlana kūlohelohe: ʻO ka poʻe i loaʻa ka moʻolelo ʻohana o nā anemias hoʻoilina e like me thalassemia a i ʻole ka anemia cell sickle e koho paha e nānā no kēia mau maʻi genetika ma mua o ka loaʻa ʻana o nā keiki. E kuhikuhi ana kahi hemoglobin electrophoresis inā aia kekahi ʻano maʻamau o ka hemoglobin i hoʻokumu ʻia e nā maʻi genetics. Nānā pinepine ʻia nā keiki hānau hou no kēia mau maʻi hemoglobin. E makemake paha kāu kauka e hoʻāʻo i kāu keiki inā he moʻolelo ʻohana kāu no ka hemoglobin abnormal a i ʻole he anemia ko lākou no ka ʻole o ka hao.
Kahi a pehea e lawelawe ʻia ai kahi hōʻike hemoglobin electrophoresis
ʻAʻole pono ʻoe e hana i kahi mea kūikawā e hoʻomākaukau ai no ka electrogores hemoglobin.
Pono ʻoe e hele i kahi hale hana e huki ʻia kou koko. Ma ke keʻena hoʻokolohua, lawe ka mea mālama ola i kahi laʻana o ke koko mai kou lima a lima paha: Hoʻomaʻemaʻe mua lākou i ka pūnaewele me kahi pā o ka ʻānai ʻana i ka waiʻona. A laila hoʻokomo lākou i kahi nila liʻiliʻi me ka paipu i hoʻopili ʻia e hōʻiliʻili i ke koko. Ke huki ʻia ke koko, lawe lākou i ka nila a uhi i ka pūnaewele me ka pad gauze. Hoʻouna lākou i kāu hāpana koko i kahi keʻena hoʻokolohua no ka loiloi.
I loko o ke keʻena hoʻokolohua, kahi kaʻina i kapa ʻia electrophoresis e hele i kahi kaila uila ma o ka hemoglobin i kāu hāpana koko. ʻO kēia ke kumu o ka hoʻokaʻawale ʻana i nā ʻano hemoglobin i nā kāʻei like ʻole. Hoʻohālikelike ʻia kāu laʻana koko i kahi laʻana olakino e hoʻoholo ai i nā ʻano hemoglobin e kū nei.
Nā pilikia o ka electrogoresis hemoglobin
E like me nā hoʻāʻo ʻana o ke koko, aia nā liʻiliʻi liʻiliʻi. Pākuʻi ʻia kēia mau mea:
- ʻāpala
- kahe ana ke koko
- maʻi ma ka puncture kahua
I nā hihia kakaikahi, huehu paha ka aa ma hope o ka huki ʻia ʻana o ke koko. ʻO kēia ʻano, i ʻike ʻia ma ke ʻano he phlebitis, hiki ke mālama ʻia me kahi kaomi mahana i nā manawa he nui i ka lā. Hiki ke pilikia ke kahe mau ʻana inā loaʻa ʻoe i kahi maʻi kahe o ke kahe a i ʻole ke lawe nei ʻoe i nā lāʻau hoʻoliʻiliʻi koko, e like me warfarin (Coumadin) a i ʻole aspirin (Bufferin).
He aha ka mea e manaʻo ai ma hope o ka hoʻāʻo
Inā hōʻike kāu hopena i nā pae hemoglobin abnormal, e hoʻokumu ʻia lākou e:
- hemoglobin C maʻi, kahi maʻi genetical e hiki ai i ka anemia koʻikoʻi
- he hemoglobinopathy laha ʻole, kahi hui o nā maʻi kūlohelohe e hana ana i ka hana maʻamau a i ʻole ke kūkulu ʻana o nā hunaola ʻulaʻula
- anemia maʻi ʻaʻai
- thalassemia
E hana kāu kauka i nā hoʻokolohua ukali inā hōʻike ʻia kahi hōʻike hemoglobin electrophoresis he ʻano maʻamau kou o ka hemoglobin.