Nā Fecal Transplants: Ke Ki i ka hoʻomaikaʻi ʻana i ke olakino Gut?
Anter
- He aha kahi transplant fecal?
- Pehea e hana ai?
- Kolonekia
- ʻO Enema
- Tube Nasogastric
- Kāpena
- Hana ia i kekahi hopena?
- No hea mai ka pākeke?
- He aha nā pōmaikaʻi no ka mālama ʻana i nā maʻi ʻo C. Diff?
- He aha e pili ana i nā pono no nā kūlana ʻē aʻe?
- ʻO ka maʻi huhū huhū (IBS)
- Ulcerative colitis (UC)
- ʻO ka maʻi maʻi Autism (ASD)
- Kaumaha emi
- ʻO wai ka mea pono ʻole ke lawe i ka fecal transplant?
- He aha ke kūlana o ka FDA?
- He aha e pili ana i nā kuʻi fecal DIY?
- Ke laina lalo
He aha kahi transplant fecal?
ʻO kahi transplant fecal kahi hana e hoʻoili i ka pahu mai kahi mea hāʻawi i ka gastrointestinal (GI) tract o kahi kanaka ʻē aʻe no ke kumu o ka mālama ʻana i kahi maʻi a kūlana paha. Kapa ʻia ia he transplant microbiota fecal (FMT) a i ʻole bacteriotherapy.
Ke lilo nei lākou i mea makemake nui ʻia e like me ka ʻike ʻana o ka poʻe i ka mea nui o ka microbiome ʻōpū. ʻO ka manaʻo ma hope o nā transporal fecal e kōkua lākou e hoʻolauna i nā koʻohune ʻoi aku ka maikaʻi i kāu kahawai GI.
Ma ka huli, hiki i kēia mau koʻohune kōkua ke kōkua kūʻē i ke ʻano o nā kūlana olakino, mai nā maʻi GI a i ka maʻi maʻi autism (ASD).
Pehea e hana ai?
Nui a hewahewa nā ʻano hana no ka hoʻokō ʻana i kahi transplant fecal, kēlā me kēia me kā lākou pono ponoʻī.
Kolonekia
Hāʻawi kēia hana i kahi hoʻomākaukau wai e kū pololei i loko o kou ʻōpū nui ma o kahi kolona. ʻO ka manawa pinepine, kaomi ʻia ka pahu kolona ma o ka piha o kou ʻōpū nui. I ka huki ʻana o ka pahu, hoʻokomo i ka transplant i kāu ʻōpū.
Loaʻa ka maikaʻi o ka ʻae ʻana i nā kauka i ka ʻae ʻana i nā kauka e ʻike i nā wahi o kou ʻōpū nui e hiki ke hōʻino ʻia ma muli o kahi ʻano paʻa.
ʻO Enema
E like me ka hoʻokokoke ʻana o ke kolona, hoʻolauna kēia hana i ka transplant i loko o kou ʻōpū nui ma o ka enema.
E noi ʻia paha ʻoe e moe ma kou ʻaoʻao ke hoʻokiʻekiʻe ʻia kou kino haʻahaʻa. ʻOi aku ka maʻalahi o kēia transplant i kou ʻōpū. ʻO ka mea aʻe, ua hoʻokomo mālie ʻia kahi kihi enema lubricated i kāu kiko. ʻO ka transplant, aia i loko o kahi ʻeke enema, a laila ʻae ʻia e kahe i ka pololei.
ʻO nā transfants fecal i hāʻawi ʻia e ka enema ka mea maʻamau o ka invasive a me ka haʻahaʻa o ke kumukūʻai ma mua o nā kolone.
Tube Nasogastric
I kēia kaʻina hana, hāʻawi ʻia kahi hoʻomākaukau wai i kou ʻōpū ma o kahi paipu e kahe ana i loko o kou ihu. Mai kou ʻōpū, hele ka mea hana i kāu ʻōpū.
ʻO ka mea mua, hāʻawi ʻia ʻoe i ka lāʻau e hōʻoki i kou ʻōpū mai ka hana ʻana i ka waikawa i hiki ke pepehi i nā meaola kōkua i ka hoʻomākaukau transplant.
A laila, kau ʻia ka paipu i loko o kou ihu. Ma mua o ke kaʻina hana, e nānā kahi ʻoihana olakino i ke kau ʻana o ka paipu me ka hoʻohana ʻana i ka ʻenehana kiʻi. Ke hoʻonohonoho pololei ʻia, e hoʻohana lākou i kahi syringe e hoʻoliʻiliʻi i ka hoʻomākaukau ma o ka paipu a i loko o kou ʻōpū.
Kāpena
ʻO kēia kahi hana hou o ka transplant fecal e pili ana i ka ale ʻana i nā pila i loaʻa kahi hoʻomākaukau noho. Hoʻohālikelike ʻia me nā ʻano hana ʻē aʻe, ʻo ia ka invasive liʻiliʻi loa a hiki ke hana maʻamau i kahi keʻena olakino a i ʻole ma ka home.
Hoʻohālikelike kahi 2017 i kēia ala i kahi kolonekia i nā mākua me ka hoʻi hou ʻana Difficile Clostridium maʻi maʻi. ʻAʻole i ʻike ʻia ka liʻiliʻi o ka capsule ma mua o kahi kolonexopika e pili ana i ka pale ʻana i nā maʻi hou no 12 mau pule.
Eia nō naʻe, pono kēia hana o ka ale ʻana i nā capsule i ka noi hou ʻana e hoʻomaopopo piha i ka hopena a me ka palekana.
Hana ia i kekahi hopena?
Ma hope o kahi kanu fecal, ʻike paha ʻoe i kekahi mau hopena ʻaoʻao, e like me:
- hōʻoluʻolu o ka ʻōpū a i ʻole ke ʻūlū ʻana
- kōpaʻa
- ʻōhūhū
- pāhoehoe
- belching a palu paha
Kāhea koke aku i kāu kauka inā he koʻikoʻi ka ʻeha a i ʻole ʻike ʻoe i kekahi.
- ʻōpū nui o ka ʻōpū
- ka luaʻi
- ke koko i loko o kāu pahu
No hea mai ka pākeke?
ʻO ka pahu i hoʻohana ʻia i nā transporal fecal mai nā mea hāʻawi manawaleʻa kanaka. Kaukaʻi ʻia i ka hana, hana ʻia ka stool i wai wai a i ʻole hoʻomaloʻo ʻia i loko o kahi mea kanu.
Pono nā mea hāʻawi manawaleʻa e hana i nā hoʻokolohua like ʻole, e like me:
- nā hoʻāʻo ʻana i ke koko e nānā no ka maʻi hepa, HIV, a me nā kūlana ʻē aʻe
- nā hoʻāhu o ka noho a me nā moʻomeheu e nānā ai no nā parasite a me nā ʻōuli ʻē aʻe o kahi ʻano paʻa
Hele pū kekahi nā mea hāʻawi i kahi kaʻina kānana e hoʻoholo inā lākou:
- ua lawe i nā antibiotic i loko o nā mahina ʻeono i hala
- loaʻa i kahi ʻōnaehana pale pale kūpikipiki
- he moʻolelo o ka moekolohe moekolohe kiʻekiʻe, me ka moe kolohe me ka pale ʻole o ka pale
- i loaʻa i ka peʻa a i ʻole ke ʻōkuʻu kino i nā mahina ʻeono i hala
- he moʻolelo o ka hoʻohana lāʻau
- ua huakaʻi hele i nā ʻāina me nā helu kiʻekiʻe o nā maʻi parasito
- loaʻa kahi maʻi GI mau, e like me ka maʻi ʻōpū
E ʻike paha ʻoe i nā pūnaewele e hāʻawi ana i nā laikini fecal ma o ka leka uila. Inā ʻoe e noʻonoʻo ana i kahi transplant fecal, e hana pono me kāu kauka olakino e hōʻoia i ka loaʻa ʻana o kahi laʻana mai kahi mea hāʻawi manawaleʻa.
He aha nā pōmaikaʻi no ka mālama ʻana i nā maʻi ʻo C. Diff?
C. ʻokoʻaʻike ʻia nā maʻi he paʻakikī e mālama. E pili ana i ka poʻe i mālama ʻia me nā antibiotic no a C. ʻokoʻa maʻi e hele a hoʻomohala i kahi maʻi hou. Hoʻohui, kūpaʻa antibiotic i C. ʻokoʻa ke hoʻonui nei.
C. ʻokoʻa hiki mai nā maʻi ke loaʻa ka ulu nui o nā koʻohune i kāu palapala GI. Wahi a ka American College of Gastroenterology, 5 a 15 pākēneka o nā mākua olakino - a me 84.4 pakeneka o nā keiki hānau hou a me nā pēpē olakino - he nui maʻamau o C. ʻokoʻa i ko lākou ʻōpū. ʻAʻole ia e hoʻopilikia i nā pilikia a kōkua i ka mālama ʻana i ka nui o ka maʻi koʻohune o ka ʻōpū.
Eia nō naʻe, mālama nā bacteria ʻē aʻe i kou ʻōpū i ka heluna kanaka o C. ʻokoʻa i ka hōʻoia, e pale ana iā ia mai ka maʻi. Hiki i kahi transplant fecal ke kōkua i ka hoʻihoʻi hou ʻana i kēia mau koʻohune i loko o kāu palapala GI, e ʻae iā lākou e pale i ka ulu o ka wā e hiki mai ana. C. ʻokoʻa
Kaha hōʻikeʻO ka hapa nui o nā noiʻi e kū nei e pili ana i ka hoʻohana ʻana i nā transporus fecal no ka mālama ʻana i C. ʻokoʻa liʻiliʻi nā maʻi. Eia naʻe, ua hana ka hapanui i nā hopena like e hōʻike ana i kahi helu o ka hōʻola o nā mea ʻoi aku.
He aha e pili ana i nā pono no nā kūlana ʻē aʻe?
Ke ʻimi nei nā poʻe loea pehea e hiki ai i nā kuʻi fecal ke kōkua me nā kūlana ʻē aʻe a me nā pilikia olakino, me nā kūlana GI ʻē aʻe. Aia ma lalo kahi kiʻi o kekahi o ka noiʻi a hiki i kēia manawa.
ʻOiai ke hoʻohiki nei kekahi o kēia mau hopena, aia nō i kahi pono nui e pono ai ka noiʻi hou ʻana ma kēia wahi e hoʻoholo ai i ka maikaʻi a me ka palekana o nā transporal fecal no kēia mau hoʻohana.
ʻO ka maʻi huhū huhū (IBS)
ʻO kahi loiloi hou o nā noi eiwa i ʻike ʻia ua hoʻonui nā fecal transplants i nā ʻōuli IBS o nā mea komo. Eia nō naʻe, ʻokoʻa nā ʻeiwa mau noiʻi i kā lākou pae hoʻohālikelike, ke ʻano, a me ke kālailai.
Ulcerative colitis (UC)
Hoʻohālikelike ʻehā mau hoʻāʻo i ka helu remission o UC i ka poʻe i loaʻa kahi transplant fecal me kahi placebo. ʻO ka poʻe i loaʻa kahi fecal transplant i loaʻa ka helu remission o 25 pākēneka, hoʻohālikelike ʻia me 5 pākēneka no ka poʻe i ka placebo group.
E hoʻomanaʻo i ke kala ʻana e pili ana i kahi manawa me ka ʻole o nā hōʻailona. Hiki i nā poʻe me UC ke kala aku nei ke hoʻomau i ka hoʻomālamalama ʻana i nā wā e hiki mai ana a i ʻole nā hōʻailona.
ʻO ka maʻi maʻi Autism (ASD)
Ua ʻike ʻia kahi mea liʻiliʻi i kahi regimen transplant trans fecal lōʻihi no ʻehiku a ʻewalu mau pule i hoʻohaʻahaʻa i nā ʻōnaehana digestive i nā keiki me ASD. Ua hoʻomaikaʻi pū ʻia nā ʻōuli behavioral o ASD.
Ua ʻike mau ʻia kēia mau hoʻomaikaʻi i ʻewalu mau pule ma hope o ka mālama ʻana.
Kaumaha emi
I kēia mau lā i loko o nāʻiole i komo i ʻelua mau hui: hānai kekahi i ka papaʻai momona kiʻekiʻe a hānai kekahi i kahi papaʻai momona momona maʻamau a kau ʻia i kahi regimen hoʻoikaika kino.
Loaʻa i nā ʻiole ma ka papa momona momona nā transfants fecal mai nāʻiole i ka hui ʻelua. Ua ʻike ʻia kēia e hoʻoliʻiliʻi i ka mumū a hoʻomaikaʻi i ka metabolism. Ua ʻike pū lākou i kekahi mau microbes e pili ana i kēia mau hopena, ʻoiai ʻaʻole maopopo i ka unuhi ʻana o kēia mau hopena i nā kānaka.
E heluhelu hou aʻe e pili ana i ka loulou ma waena o ke kaupaona a me ka bacteria koʻohuna.
ʻO wai ka mea pono ʻole ke lawe i ka fecal transplant?
ʻAʻole koi ʻia nā transplant fecal no ka poʻe i pale i ka palekana ma muli o:
- nā lāʻau e kāohi i ka ʻōnaehana pale
- HIV
- maʻi maʻi akeake, e like me cirrhosis
- kahi hoʻoneʻe iwi o ka iwi i hala iho nei
He aha ke kūlana o ka FDA?
ʻOiai ke hoʻohiki nei nā noiʻi e pili ana i nā transfants fecal, ʻaʻole i ʻae ka Food and Drug Administration (FDA) iā lākou no ka hoʻohana lāʻau lapaʻau a manaʻo iā lākou he lāʻau noiʻi.
I ka mua, makemake nā kauka e makemake e hoʻohana i nā transporus fecal i ka FDA ma mua o ka hana ʻana i ke kaʻina hana. Ua pili kēia i kahi hana ʻae lōʻihi e hoʻonāwaliwali ai i nā mea he nui mai ka hoʻohana ʻana i nā transporus fecal.
Ua hoʻomaha ka FDA i kēia koi no nā transplants fecal i manaʻo ʻia e mālama i ka hoʻi hou ʻana C. ʻokoʻa nā maʻi i pane ʻole i nā antibiotic. Akā pono nā kauka e noi no nā hoʻohana ma waho o kēia hanana.
He aha e pili ana i nā kuʻi fecal DIY?
Piha ka pūnaewele i ka pehea e hana ai i kahi transplant fecal ma ka home. A ʻo ke ala paha o ke DIY e like paha me ke ala maikaʻi e hoʻopuni ai i nā lula a FDA, ʻaʻole ia he manaʻo maikaʻi.
Eia kekahi mau kumu no ke aha:
- Me ka nānā ʻole ʻia o kahi mea hāʻawi manawaleʻa, ke hoʻokau nei paha ʻoe iā ʻoe iho i ka loaʻa ʻana o ka maʻi.
- He hoʻomaʻamaʻa nui nā kauka e hana i nā transfec fecal i ka hana palekana ʻana i kahi noho no ka transplant.
- ʻO ka noiʻi ʻana i nā hopena lōʻihi a me ka palekana o nā transporal fecal ua kaupalena ʻia, keu no nā kūlana ʻē aʻe C. ʻokoʻa maʻi maʻi.
Ke laina lalo
ʻO nā kuʻi fecal kahi mea hiki ke mālama ʻia no kahi ʻano o nā kūlana. I kēia lā, hoʻohana mua ʻia lākou e mālama i ka hana hou ʻana C. ʻokoʻa nā maʻi maʻi.
I ka ʻike ʻana o ka poʻe loea e pili ana i nā kuʻi fecal, lilo lākou i koho no nā kūlana ʻē aʻe, mai nā pilikia GI a i kekahi mau kūlana hoʻomohala.