Kahi alakaʻi maʻalahi i ka ʻōnaehana Endocannabinoid

Anter

• Pehea e hana ai?
• Endocannabinoids
• Nā lāʻau loaʻa Endocannabinoid
• Nā Enzim
• He aha kāna hana?
• Pehea ʻo THC e launa pū ai me ka ECS?
• Pehea ʻo CBD e launa pū ai me ka ECS?
• Pehea e pili ana i ka hemahema endocannabinoid?
• Ke laina lalo

ʻO ka ʻōnaehana endocannabinoid (ECS) kahi ʻōnaehana hōʻailona hōʻailona paʻakikī i ʻike ʻia i nā 1990 mua e nā mea noiʻi e ʻimi nei iā THC, kahi cannabinoid kaulana. Cannabinoids kahi hui i loaʻa i ka cannabis.

Ke hoʻāʻo nei ka poʻe loea e hoʻomaopopo piha i ka ECS. Akā i kēia manawa, ʻike mākou he mea nui ia i ka hoʻoponopono ʻana i kahi o nā hana a me nā kaʻina hana, e like me:

• hiamoe
• naʻau
• ʻono ʻai
• hoʻomanaʻo
• ka hana hou a me ka momona

Aia ka ECS a hana i kou kino inā ʻaʻole ʻoe e hoʻohana i ka lāʻau.

E heluhelu e aʻo hou e pili ana i ka ECS e pili ana i ka hana a me ka launa pū ʻana me ka cannabis.

Pehea e hana ai?

Hoʻopili ka ECS i ʻekolu mau mea nui: endocannabinoids, nā mea loaʻa, a me nā enzymes.

Endocannabinoids

ʻO Endocannabinoids, i kapa ʻia hoʻi he endogenous cannabinoids, he mau mole i hana ʻia e kou kino. Ua like lākou me nā cannabinoids, akā hana ʻia e kou kino.

Ua ʻike nā loea i ʻelua endocannabinoids kī i kēia manawa:

• anandamide (AEA)
• 2-arachidonoylglyerol (2-AG)

Kōkua kēia mau mea i ka holo ʻana o nā hana kūloko. Hoʻopuka kou kino iā lākou e like me ka mea e pono ai, e paʻakikī e ʻike i nā pae maʻamau no kēlā me kēia.

Nā lāʻau loaʻa Endocannabinoid

Loaʻa kēia mau mea loaʻa i loko o kou kino. Hoʻopili iā Endocannabinoids iā lākou i mea e hōʻailona ai e pono i ka ECS ke hana.

ʻElua mau hope nui endocannabinoid:

• CB1 mau mea loaʻa, i loaʻa ka hapanui i loko o ka ʻōnaehana makaʻu waena
• CB2 nā mea loaʻa, i loaʻa ka hapanui i kāu ʻōnaehana ʻōnaehana ākea, keu hoʻi nā pūnaewele pale

Hiki i nā Endocannabinoids ke hoʻopaʻa i nā mea ʻelua paha. Pili nā hopena i ka hopena i kahi o ka receptor a me kahi endocannabinoid e hoʻopaʻa ai iā ia.

ʻO kahi laʻana, hoʻokumu paha nā endocannabinoids i nā mea loaʻa CB1 i kahi ʻāʻī o ke kuamoʻo e hoʻomaha ai i ka ʻeha. Hoʻopaʻa paha nā poʻe ʻē aʻe i kahi receptor CB2 i loko o kāu mau hunaola pale e hōʻailona ai i ka loaʻa ʻana o kou kino i ka mumū, kahi hōʻailona maʻamau o nā maʻi autoimmune.

Nā Enzim

Na Enzymes ke kuleana no ka haki ʻana i nā endocannabinoids ke hana lākou i kā lākou hana.

ʻElua kumu nui o nā enzyme kuleana e pili ana i kēia:

• hydrolase amide acid amide, e wāwahi iā AEA
• ʻo ka monoacylglycerol acid lipase, ka mea maʻamau e wāwahi i ka 2-AG

He aha kāna hana?

Paʻakikī ka ECS, a ʻaʻole i hoʻoholo pono ka poʻe loea i ka hana a i kāna mau hana hiki.

ua hoʻopili ka ECS i nā kaʻina hana penei:

• ʻono a me ka digestion
• kinikini
• ʻeha mau
• pehu a me nā pane ʻōnaehana pale ʻē aʻe
• naʻau
• ke aʻo ʻana a me ka hoʻomanaʻo ʻana
• kāohi kaʻa
• hiamoe
• ʻōnaehana ʻōnaehana lolo
• hoʻāʻo mākala
• hoʻoponopono hou ʻana i ka iwi a me ka ulu ʻana
• hana ate
• hana ʻōnaehana hoʻohua
• hoʻoluhi
• ka hana ʻili a me ke aʻalolo

Hāʻawi kēia mau hana i ka homeostasis, e pili ana i ke kūpaʻa o kāu kaiapuni kūloko. ʻO kahi laʻana, inā he ikaika i waho, e like me ka ʻeha mai kahi ʻeha a kuni paha, hoʻolei i ka homeostasis o kou kino, kiki i kāu ECS e kōkua i kou kino e hoʻi i kāna hana kūpono.

I kēia lā, manaʻo ka poʻe loea i ka mālama ʻana i ka homeostasis inā ʻo ka hana mua o ka ECS.

Pehea ʻo THC e launa pū ai me ka ECS?

ʻO Tetrahydrocannabinol (THC) kekahi o nā cannabinoids nui i loaʻa i ka cannabis. ʻO ia ka mea hoʻohui e hoʻokau iā ʻoe i "kiʻekiʻe."

I hoʻokahi manawa i kou kino, hui pū ʻo THC me kāu ECS ma ka hoʻopaʻa ʻana i nā mea loaʻa, e like me endocannabinoids. He ikaika kekahi hapa no ka mea hiki iā ia ke hoʻopaʻa i nā CB1 a me nā CB2 ʻelua.

ʻAe kēia iā ia e loaʻa i kahi o nā hopena i kou kino a me kou noʻonoʻo, ʻoi aku kekahi i makemake ʻia ma mua o nā mea ʻē aʻe. ʻO kahi laʻana, kōkua paha ʻo THC e hōʻemi i ka ʻeha a hoʻoulu i kou makemake. Akā hiki ke kumu i ka paranoia a me ka hopohopo i kekahi mau hihia.

Ke nānā nei ka poʻe loea i kēia manawa i nā ala e hana ai i ka THC cannabinoids synthetic e launa pū me ka ECS i nā ala maikaʻi wale nō.

Pehea ʻo CBD e launa pū ai me ka ECS?

ʻO ka cannabinoid nui ʻē aʻe i loaʻa i ka cannabis ʻo cannabidiol (CBD). ʻAʻole like me THC, ʻaʻole ʻo CBD e hoʻolilo iā ʻoe i "kiʻekiʻe" a ʻaʻole no ka hopena o nā hopena maikaʻi ʻole.

ʻAʻole maopopo loa ka poʻe loea i ka launa pū ʻana o CBD me ka ECS. Akā ʻike lākou ʻaʻole pili ia i CB1 a i ʻole CB2 mau mea loaʻa i ke ala o THC.

Ma kahi o, manaʻo ka poʻe he hana ia ma ka pale ʻana i nā endocannabinoids mai ka wāwahi ʻia ʻana. ʻAe kēia iā lākou e loaʻa hou ka hopena i kou kino. Manaʻo kekahi he ʻāpana ʻo CBD i kahi mea loaʻa i loaʻa ʻole i kēia manawa.

ʻOiai ke kūkākūkā ʻia nei nā kikoʻī e pili ana i ka hana ʻana, hōʻike ka noiʻi e hiki i ka CBD ke kōkua me ka ʻeha, kahoho, a me nā ʻōuli ʻē aʻe e pili ana i nā kūlana he nui.

Pehea e pili ana i ka hemahema endocannabinoid?

Manaʻo kekahi poʻe loea i ke kumumanaʻo i kapa ʻia ʻo defocannabinoid deficit (CECD). Hōʻike kēia kumumanaʻo e hiki i nā pae endocannabinoid haʻahaʻa i loko o kou kino a i ʻole ECS hana kūpono ke kōkua i ka hoʻomohala ʻana i kekahi mau ʻano.

Kuhi kahi loiloi ma luna o 10 mau makahiki o ka noiʻi e pili ana i ke kumuhana e hōʻike i ke kumumanaʻo i hiki ke wehewehe i ke kumu e ulu ai kekahi poʻe i ka migraine, fibromyalgia, a me ka maʻi hanu huhū.

ʻAʻohe o kēia mau kūlana he kumu kumu maopopo. Kū pinepine hoʻi lākou i ka lāʻau lapaʻau a i kekahi manawa kū kekahi me kekahi.

Inā hana ʻo CECD i kekahi ʻano hana i kēia mau ʻano, ke kuhi nei i ka ECS a i ʻole ka endocannabinoid hana hiki ke lilo i ke kī hemahema no ka mālama ʻana, akā pono ka noiʻi hou aku.

Ke laina lalo

He kuleana nui ka ECS i ka mālama ʻana i kāu mau kaʻina hana i loko. Akā aia nō ka nui o kā mākou ʻike ʻole e pili ana. Ke hoʻomohala nei ka poʻe loea i ka ʻike ʻoi aku ka maikaʻi o ka ECS, hiki iā ia ke hoʻopaʻa i ke kī i ka mālama ʻana i nā ʻano he nui.