EGCG (Epigallocatechin Gallate): nā pono, nā hana, a me ka palekana

Anter

• He aha ka EGCG?
• Loaʻa kūlohelohe i nā meaʻai like ʻole
• Hāʻawi paha i nā pono olakino ikaika
• Nā hopena Antioxidant a me anti-inflammatory
• ʻO ke olakino puʻuwai
• Kaumaha emi
• Ola olakino
• Ka hana a me nā hopena ʻē aʻe
• Nā hopena ʻē aʻe
• Ke laina lalo

ʻO ka Epigallocatechin gallate (EGCG) kahi mea kanu mea kanu kū hoʻokahi e kiʻi nui i ka nānā no kāna hopena maikaʻi i ke olakino.

Manaʻo ʻia e hoʻoliʻiliʻi i ka hoʻāhu, kōkua i ka pohō kaumaha, a kōkua i ka pale ʻana i ka maʻi puʻuwai a me ka lolo.

Loiloi kēia ʻatikala iā EGCG, me nā pono olakino a me nā hopena ʻē aʻe.

He aha ka EGCG?

ʻIke ʻia ma ke ʻano he epigallocatechin gallate, ʻo EGCG kahi ʻano o nā mea kanu i hoʻokumu ʻia me nā mea kanu i kapa ʻia ʻo catechin. Hoʻokaʻawale hou ʻia ʻo Catechins i kahi hui nui o nā mea kanu i ʻike ʻia ʻo polyphenols ().

Hana ʻo EGCG a me nā catechins ʻē aʻe e like me nā antioxidants ikaika e pale aku ai i ka hōʻino ʻana o ke kelepona i hoʻokumu ʻia e nā radical free ().

ʻO nā radical manuahi kahi ʻāpana reactive re i hana ʻia i loko o kou kino i hiki ke hōʻino i kāu mau pūnaewele ke kiʻekiʻe loa kā lākou helu. ʻO ka ʻai ʻana i nā meaʻai kiʻekiʻe i loko o nā antioxidants e like me catechins hiki ke kōkua i ka hōʻemi ʻana i nā hōʻino kūʻokoʻa manuahi.

Hoʻohui ʻia, ʻimi nā noiʻi e hiki i nā catechins e like me EGCG ke hōʻemi i ka mumū a pale i kekahi mau maʻi maʻamau, e like me ka maʻi puʻuwai, ka maʻi diabetes, a me kekahi mau maʻi ʻino (,).

Aia kūlohelohe ʻo EGCG i loko o nā meaʻai kanu mea kanu akā loaʻa pū ʻia me ke ʻano he papaʻai meaʻai i kūʻai pinepine ʻia ma ke ʻano o kahi ʻūlū.

ʻO EGCG kahi ʻano mea kanu i kapa ʻia ʻo catechin. Hōʻike ka noiʻi e hana paha nā catechins e like me EGCG i ka pale ʻana i kāu mau pūnaewele mai ka hōʻino a me ka pale ʻana i ka maʻi.

Loaʻa kūlohelohe i nā meaʻai like ʻole

ʻIke ʻia paha ʻo EGCG no kāna kuleana ma ke ʻano he hui nui nui i ka tī ʻōmaʻomaʻo.

ʻO ka ʻoiaʻiʻo, ʻo nā pono olakino lehulehu e pili pū ana me ka inu ʻana i ka tī ʻōmaʻomaʻo e hāʻawi pinepine ʻia i kāna ʻike EGCG ().

ʻOiai ʻike ʻia ka nui o ka EGCG i ke kī ʻōmaʻomaʻo, aia nō ia i nā mea liʻiliʻi i nā meaʻai ʻē aʻe, e like me (3):

• Kī: ʻōmaʻomaʻo, keʻokeʻo, oolong, a me nā kī ʻeleʻele
• Hua: cranberry, strawberry, blackberry, kiwi, cherry, pears, peach, ʻāpala, a me nā avocados
• Hua kukui: pecans, pistachios, a me nā hazelnuts

ʻOiai ʻo EGCG ka catechin i noiʻi nui ʻia a ikaika, nā ʻano ʻē aʻe e like me epicatechin, epigallocatechin, a me epicatechin 3-gallate ke hāʻawi i nā pono like. Eia kekahi, ʻo ka hapa nui o lākou e loaʻa ākea ākea i ka lako o ka meaʻai (3,).

ʻO ka waina ʻulaʻula, kokoleka ʻeleʻele, legume, a me ka hapa nui o nā hua he mau laʻana o nā meaʻai e hāʻawi i kahi nui o nā catechins e hoʻolaha nei i ke olakino ().

Kūleʻa nui ʻia ʻo EGCG i ke kī ʻōmaʻomaʻo akā ʻike ʻia hoʻi i nā mea liʻiliʻi i nā ʻano kī ʻē aʻe, nā hua, a me kekahi mau hua kukui. ʻO nā catechin hoʻolauleʻa olakino ʻē aʻe i ka waina ʻulaʻula, kokoleka pouli, nā legume, a me ka hapa nui o nā hua.

Hāʻawi paha i nā pono olakino ikaika

Hōʻike ka paipu hoʻowalewale, holoholona, ​​a me kekahi mau haʻawina kanaka e hāʻawi ʻo EGCG i nā pono olakino he nui, e like me ka hoʻemi ʻana i ka mumū, ka pohō kaumaha, a me ka maikaʻi o ka olakino puʻuwai a me ka lolo.

ʻO ka mea hope loa, pono hou ʻia kahi noiʻi e ʻike pono pehea e hoʻohana ʻia ai ʻo EGCG ma ke ʻano he mea pale a i ʻole mālama ʻia no ka maʻi, ʻoiai ke hoʻohiki nei nā ʻikepili o kēia wā.

Nā hopena Antioxidant a me anti-inflammatory

ʻO ka hapa nui o kā EGCG koi i ka kaulana e hele mai ana mai kona mana antioxidant ikaika a me ka hiki ke hōʻemi i ke kaumaha a me ka mumū.

ʻO nā radical manuahi nā ʻāpana reactive i hiki ke hōʻino i kāu mau pūnaewele. ʻO ka hana radical manuahi i alakaʻi ʻia i ke koʻikoʻi oxidative.

Ma ke ʻano he antioxidant, pale aku ʻo EGCG i kāu mau pūnaewele mai ka hōʻino e pili ana i ke koʻikoʻi oxidative a kāohi i ka hana o nā kemika pro-inflammatory i hana ʻia i kou kino, e like me ka tumzzros factor-alpha (TNF-alpha) ().

Hoʻopili ʻia ka stress a me ka mumū i nā ʻano maʻi like ʻole, e like me ka maʻi ʻaʻai, ka maʻi kō, a me nā maʻi puʻuwai.

No laila, ʻo nā hopena anti-inflammatory a me nā antioxidant o EGCG i manaʻo ʻia kekahi o nā kumu nui no kāna noi ākea ākea ākea ().

ʻO ke olakino puʻuwai

Hōʻike ka noiʻi e hiki i ka EGCG i ke kī ʻōmaʻomaʻo ke kākoʻo i ke olakino puʻuwai ma o ka hōʻemi ʻana i ke kahe o ke koko, ka cholesterol, a me ka hōʻiliʻili o ka pā i nā kīʻaha koko - nā mea pilikia nui āpau no ka maʻi puʻuwai (,).

I loko o kahi hebedoma 8 mau pule ma 33 mau kānaka, e lawe ana i ka 250 mg o ka EGCG-i loaʻa i ka lāʻī ʻōmaʻomaʻo i kēlā me kēia lā i hopena i kahi 4.5% hōʻemi nui o ka LDL (ʻino) kolesterol ().

ʻO kahi noiʻi ʻokoʻa i 56 mau kānaka i ʻike i ka hoʻoliʻiliʻi nui i ke kahe o ke koko, ka cholesterol, a me nā marka hoʻoweliweli i kēlā mau lā e lawe nei i ka mahele lāʻau o 379 mg o nā hua kī ʻōmaʻomaʻo ma 3 mau mahina ().

ʻOiai ke paipai nei kēia mau hopena, pono hou ka noiʻi e hoʻomaopopo pono pehea ka EGCG i ke kī ʻōmaʻomaʻo e hoʻemi ai i ka maʻi maʻi puʻuwai.

Kaumaha emi

E paipai paha ʻo EGCG i ka pohō kaumaha, keu hoʻi i ka lawe ʻia ʻana me ka caffeine i loaʻa maoli i ka tī ʻōmaʻomaʻo.

ʻOiai ka hapanui o nā hualoaʻa e pili ana i ka hopena o ka EGCG ma ke kaupaona e kūlike ʻole, ua ʻōlelo ʻia kekahi mau noiʻi loiloi wā lōʻihi e ʻai ana ma kahi o 2 mau kīʻaha (14.7 auneke a i ʻole 434 ml) o ke kī ʻōmaʻomaʻo i kēlā lā i kēia lā me ka momona o ke kino a me ke kaupaona ().

Ua ʻike pū kekahi nā noiʻi kanaka hou i ka lawe ʻana i ka 100-460 mg o EGCG me 80-300 mg o ka caffeine ma kahi o 12 mau pule e pili ana i ka pohō kaumaha a me ka hoʻēmi ʻana o ka momona o ke kino ().

Eia nō naʻe, ʻaʻole ʻike mau ʻia nā loli i ke kaumaha a i ʻole ke ʻano o ke kino ke lawe ʻia ʻo EGCG me ka ʻole o ka caffeine.

Ola olakino

Hōʻike ka noiʻi mua e hiki i ka EGCG i ke kī ʻōmaʻomaʻo ke hoʻokau i ka hoʻomaikaʻi ʻana i ka hana o ka cell neurological a pale i nā maʻi lolo degenerative.

I kekahi mau noiʻi, ua hoʻomaikaʻi maikaʻi nā kuʻi ʻana o EGCG i ka mumū, a me ka hoʻōla hou ʻana a me ka hoʻōla hou ʻana o nā hunaola neural i nāʻiole me nā ʻeha o ke kuamoʻo (,).

Hoʻohui ʻia, ua loaʻa nā loiloi loiloi he nui i loko o nā kānaka i kahi loulou ma waena o kahi kiʻekiʻe o ke kī ʻōmaʻomaʻo a me ka hoʻemi ʻia ʻana o ka lolo e pili ana i ka makahiki, a me ka maʻi Alzheimer a me Parkinson. Eia naʻe, kūlike ʻole ka ʻikepili i loaʻa.

ʻO ka mea hou aku, maopopo ʻole inā EGCG kikoʻī a i ʻole nā ​​ʻāpana kemika ʻē aʻe o kēia tī i kēia mau hopena.

Pono e noiʻi hou aʻe e hoʻomaopopo pono inā paha e pale a mālama paha ʻo EGCG i nā maʻi lolo lolo i nā kānaka.

Hiki i ka EGCG i ke kī ʻōmaʻomaʻo ke hāʻawi i nā pono olakino like ʻole, e like me ka hoʻemi ʻana i ka mumū, ka pohō kaumaha, a me ka pale ʻana i nā maʻi puʻuwai a me ka lolo. Eia nō naʻe, pono hou ʻia ka noiʻi ʻana e pili ana i kona hopena.

Ka hana a me nā hopena ʻē aʻe

ʻOiai ua aʻo ʻia ʻo EGCG i mau makahiki, ua loli kona mau hopena kino.

Manaʻo kekahi poʻe loea he kumu paha kēia no ka EGCG e hoʻohaʻahaʻa maʻalahi ai i ke alo o ka oxygen, a he nui ka poʻe e ʻole e mimiki pono iā ia i ka digestive tract ().

ʻAʻole maopopo maopopo ke kumu o kēia, akā pili paha ia i ka nui o EGCG e holo wikiwiki i ka ʻōpū liʻiliʻi a hoʻopau ʻia e hoʻoweliweli ʻia e nā bacteria i loko o ka ʻōpū nui ().

Ua paʻakikī kēia i ka hoʻomohala ʻana i nā ʻōlelo koi koi kikoʻī.

ʻO ke kīʻaha hoʻokahi (8 auneke a i ʻole 250 ml) o ke kī ʻōmaʻomaʻo brewed e loaʻa mau ana ma kahi o 50-100 mg o EGCG. ʻO nā hana i hoʻohana ʻia i nā noiʻi ʻepekema e ʻoi aku ka kiʻekiʻe, akā ʻaʻole kūlike ʻole nā ​​kikoʻī (,).

ʻO nā lā i kēlā me kēia lā i loaʻa i ka 800 mg o EGCG i kēlā me kēia lā e hoʻonui i nā kiʻekiʻe o ke koko o transaminases, kahi hōʻailona o ka hōʻino o ke ake (17).

Ua hōʻike kahi hui o nā kānaka noiʻi i kahi pae palekana o 338 mg o EGCG i kēlā me kēia lā ke komo ʻia i loko o kahi palapala paʻa paʻa (18).

Nā hopena ʻē aʻe

He mea nui e hoʻomaopopo ʻaʻole ka EGCG 100% palekana a palekana ʻole paha. ʻO ka ʻoiaʻiʻo, pili nā mea hoʻopili EGCG me nā hopena koʻikoʻi, e like me ():

• hoka a me ka hakuʻala ʻole
• ʻūpā
• kō kō kō haʻahaʻa
• anemia

Ua manaʻo kekahi mau loea e pili paha kēia mau hopena maikaʻi ʻole i ka hoʻowahāwahā hoʻowahāwahā o nā mea hoʻopihapiha a ʻaʻole ka EGCG ponoʻī, akā me ka nānā ʻole, e akahele loa ʻoe inā ʻoe e noʻonoʻo ana i ka lawe ʻana i kēia waihona.

ʻAʻole koi ʻia ka lawe ʻana i nā lāʻau kākoʻo o EGCG inā hāpai ʻoe, no ka mea e hoʻopilikia paha ia i ka metabolism o ka folate - kahi huaola B e pono ai no ka ulu ʻana o ka fetal a me ka hoʻomohala ʻana - e hoʻonui ana i ka makaʻu o nā hānau hānau e like me spina bifida ()

Maopopo ʻole inā palekana ka palekana EGCG no nā wahine e hānai ana i ka waiū, no laila ʻoi aku ka maikaʻi o ka hōʻalo ʻana a hiki i ka loaʻa ʻana o ka noiʻi hou ().

Hoʻopilikia pū paha ʻo EGCG i ka lawe ʻia ʻana o kekahi mau lāʻau i kuhikuhi ʻia, e like me kekahi ʻano o ka hoʻoliʻiliʻi kolesterol a me nā lāʻau antipsychotic ().

E hōʻoia i ka palekana, e launa pinepine me kāu kauka olakino ma mua o ka hoʻomaka ʻana i kahi papaʻai papaʻai hou.

I kēia manawa ʻaʻohe ʻōlelo koi koi no EGCG, ʻoiai ʻo 800 mg i kēlā me kēia lā a hiki i ka 4 mau pule i hoʻohana palekana ʻia i nā noiʻi. Ua hoʻopili ʻia nā mea hoʻopihapiha EGCG i nā hopena ʻē aʻe a hoʻopilikia paha i ka lawe ʻana o ka lāʻau.

Ke laina lalo

He hui ikaika ʻo EGCG e pōmaikaʻi i ke olakino ma o ka hōʻemi ʻana i ka mumū, kōkua ʻana i ka pohō kaumaha, a me ka pale ʻana i kekahi mau maʻi maʻi mau.

Nui loa ia i ka tī ʻōmaʻomaʻo akā loaʻa pū i nā meaʻai mea kanu.

Ke lawe ʻia ma ke ʻano he kumukanawai, pili mau ʻo EGCG me nā hopena ʻē aʻe. ʻO ke ala palekana ʻo ke kūkākūkā ʻana me kāu kauka olakino ma mua o ka hoʻohui ʻana iā EGCG i kāu hana maʻamau e ʻike pono i kēia mea kōkua.