ʻO Calcinosis Cutis

Anter

• Nā ʻano o ka cuttis cinosinosis
• Nā ʻōuli o ka helu kuʻina calcinosis
• Nā kumu o ka make ʻana o ka calcinosis
• Ka helu helu Dystrophic
• Ka helu helu Metastatic
• Ka helu helu Idiopathic
• Ka helu helu Iatrogenic
• ʻO Calciphylaxis
• I ka hui pū ʻana me scleroderma
• Kānāwai o ka calcinosis cutis
• Hoʻomaʻamaʻa ʻana i nā kalesis cutis
• Nā lāʻau
• ʻOki kino
• Nā lapaʻau ʻē aʻe
• ʻO Outlook no ka chicinosis cutis

Hōʻike Overview

ʻO Calcinosis cutis ka hōʻuluʻulu ʻana o nā aniani paʻakai calcium i kou ʻili. ʻO nā waihona kalima he mau puʻupuʻu paʻakikī ʻaʻole e hemo. ʻOkoʻa ke kinona a me ka nui o nā leona.

He kūlana laha ʻole kēia i nā kumu like ʻole. Kūpono kēia mau mea mai ka maʻi a me ka ʻeha i nā maʻi ʻōnaehana e like me ka holo pono ʻole o ka hakuʻala.

ʻAʻohe o nā ʻōuli ma ka helu ʻana o ka calcinosis cutis. Akā i kekahi mau hihia, hiki ke hōʻeha loa. Loaʻa nā lāʻau lapaʻau, e like me ke kahakaha ʻana, akā e hoʻi hou paha nā ʻāpana calcium.

Nā ʻano o ka cuttis cinosinosis

Aia he ʻelima mau subtypes o ka helu cinosinosis cutis:

• Ka helu helu Dystrophic. ʻO kēia ka ʻano maʻamau o ka calcinosis. Hana ʻia kahi i ʻeha a ʻā ʻia hoʻi ka ʻili. ʻAʻole pili i nā pae maʻamau o ka calcium a me nā phosphore i loko o ke kino.
• Ka helu helu Metastatic. Hana ʻia kēia i ka poʻe nona nā kiʻekiʻe o ka calcium a me ka phosphorus.
• Ka helu helu Idiopathic. ʻAʻohe kumu o kēia ʻano kalcisis cutis. Hana ʻia ia ma hoʻokahi mahele o ke kino.
• Ka helu helu Iatrogenic. ʻO kēia ʻano cutraminosis cutis nā hopena mai kahi hana olakino a i ʻole ka hoʻomaʻamaʻa, maʻamau pinepine ʻole. ʻO kahi laʻana, hiki i nā keiki hānau hou ke loaʻa kahi helu iatrogenic ma ka kuʻekuʻe, i ka hopena o nā kuʻekuʻe wāwae e lawe i ke koko.
• ʻO Calciphylaxis. ʻO kēia ʻano maʻamau a koʻikoʻi o ka calculine kaliki e hana maʻamau i ka poʻe i loaʻa ʻole ka puʻuwai, ua loaʻa kahi transplant kidney, a i ʻole ma ka dialysis. Hoʻopili ia i nā kīʻaha koko i ka ʻili a i ʻole ka momona momona.ʻAno ʻole nā ​​pae o ka aʻa a me ka phosphate i loko o ke kino.

Nā ʻōuli o ka helu kuʻina calcinosis

ʻO ka helehelena a me kahi o nā kalcisis cutis kaukaʻi ʻia i ke kumu kumu. Kūleʻa pinepine nā liona, ʻeleʻele keʻokeʻo-melemele i ka ʻili. Hoʻomaka mālie lākou a ʻokoʻa i ka nui.

ʻAʻohe o nā liona i loaʻa nā hōʻailona, ​​a ʻeha paha, ʻeha, a ʻū paha i kahi mea keʻokeʻo. I nā hihia kakaikahi, lilo ka liona i mea hoʻoweliweli i ke ola.

Eia nā ʻāpana kahi e ʻike pinepine ʻia ai nā leona i kēlā me kēia subtypes o ka calcinosis cutis:

• Ka helu helu Dystrophic. Kū nā puʻupuʻu i kahi o ka hōʻino kino. ʻO nā wahi maʻamau ka forearms, kuʻekuʻe lima, nā manamana lima, a me nā kuli. Me ka lupus, hiki i nā lehelehe ma nā lima a me nā wāwae, ka pūpū, a ma lalo o nā lehelehe lupus.
• Ka helu helu Metastatic. Aia nā puʻupuʻu me ka symmetrically a puni nā hono: nā kuli, nā kuʻe lima, a i ʻole nā ​​poʻohiwi. Hiki paha iā lākou ke hana a puni i nā mea o loko, e like me nā mumū, nā puʻupaʻa, nā kīʻaha koko, a me ka ʻōpū. Hiki i nā leona a puni nā hono ke kaupalena i ka neʻe ʻana i ka paʻakikī o ka ʻili.
• Ka helu helu Idiopathic. Hoʻopili kēia i kahi mahele o ke kino wale nō. Hiki iā ia ke hana a puni nā hono nui, ka scrotum, ke poʻo, ka umauma, ka peni, ka puʻupuʻu, a i ʻole nā ​​lima a me nā wāwae. I nā kamaliʻi paha ma ka maka. He puka keʻokeʻo paha nā leona.
• Ka helu helu Iatrogenic. Hōʻike ʻia ka leona ma ke kahua o kahi lāʻau lapaʻau a i ʻole therapeutic kaʻina hana e hou i ka ʻili.
• ʻO Calciphylaxis. ʻO nā ʻili ʻili ka maʻa mau ma nā wāwae a i ʻole ke kumu, ʻo ia hoʻi nā wahi momona e like me ka umauma, ka ʻū, a me ka ʻōpū. Hoʻopili ʻia nā liona i ka nānā ʻana a ʻeha hoʻi. Hiki iā lākou ke lilo i ulcer e hoʻōla ʻole, a i ʻole hiki iā lākou ke hoʻomohala i ka gangrene. Hiki pū me nā leona me nā ʻōuli ʻē aʻe, e like me ka luhi a me ka nāwaliwali.

Nā kumu o ka make ʻana o ka calcinosis

He kākaʻikahi ʻo Calcinosis cutis akā he ākea nā kumu, kaukaʻi ʻia i ka subtype:

Ka helu helu Dystrophic

Ma ka laulaha, hiki ke hōʻino kino i nā protein phosphate i hoʻokuʻu ʻia e nā make make a laila helu ʻia, e hana ana i nā paʻakai kalipona. Hiki i ka hōʻino kino ke hele mai:

• nā maʻi maʻi
• ʻōiwi
• huehue
• nā maʻi nā mea hoʻopili e like me lupus, sclerosis ʻōnaehana, a dermatomyositis paha

Ka helu helu Metastatic

Ke kiʻekiʻe kiʻekiʻe o ka calcium phosphate o ke kino, hana ia i nā paʻakai kalipona e hana i nā nodule ma ka ʻili. ʻO nā kumu o nā pae maʻamau o ka calcium a me ka phosphate:

• maʻi kōpaʻa paʻa (ke kumu maʻamau)
• nui loa ka wikamina D
• hyperparathyroidism (kahi gland parathyroid hoʻonui ʻia e hoʻonui nui i ka thyroid hormone)
• sarcoidosis (nā hui o nā hunaola hoʻowili i loko o nā akemāmā, nā pūnana lymph, ka ʻili, a me nā ʻāpana ʻē aʻe o ke kino)
• ka waiū-alkali maʻi (ʻo ka nui o ka puna mai nā meaʻai a i ʻole antacids)
• nā maʻi iwi, e like me ka maʻi o Paget

Ka helu helu Idiopathic

ʻAʻole like me nā ʻano ʻelua o ka make mua helu mua, ua helu ʻia ka helu helu idiopathic me ka ʻole o ka ʻeha o ke aʻa a ʻaʻohe pae o ka calcium a me ka phosphore. ʻO ka manaʻo ʻIdiopathic "ʻaʻohe kumu i ʻike ʻia." ʻEkolu ʻano:

• nodule ʻohana, i ʻike mau ʻia i nā ʻōpio olakino a i ʻole nā ​​keiki ʻōpio
• subepidermal nodules, i hōʻike pono ʻia ma lalo pono o ka ʻili
• nodule ma ka scrotum

Ka helu helu Iatrogenic

ʻO ke kumu o ka helu ʻana o ka iatrogenic kahi hana olakino e alakaʻi kuhi hewa ʻia ai i nā waihona paʻakai paʻakai ma ke ʻano he hopena ʻaoʻao. ʻAʻole ʻike ʻia ka mīkini no kēia. ʻO kekahi o nā kaʻina hana e pili ana:

• ka hoʻoponopono ʻana i nā hopena e loaʻa ana ka calcium a me ka phosphate
• hoʻolōʻihi lōʻihi me ka saturation calcium chloride electrode paste i loko o kahi electroencephalograph a i ʻole electromyograph
• intravenous calcium gluconate, calcium chloride, a me para-aminosalicylic acid i ka mālama ʻia ʻana o ka tuberculosis
• lāʻau kuʻekuʻe wāwae i nā keiki hānau hou

ʻO Calciphylaxis

ʻAʻole maopopo ke kumu o ka calciphylaxis. He mea kākaʻikahi loa ia, ʻoiai ʻo kekahi o nā mea pili e like me ka maʻamau.

• holo pono kīnā ʻole
• momona
• diabetes
• hyperparathyroidism

I ka hui pū ʻana me scleroderma

Kū pinepine ʻo Calcinosis cutis me ka sclerosis ʻōnaehana (scleroderma). ʻIke ʻia ia ma ke ʻano kaupalena o kēia maʻi, i ʻike ʻia ʻo sclerosis ʻōnaehana cutaneite palena (CREST).

Kuhi ʻia kahi poʻe me ka maʻi CREST e hoʻonui i ka calcinosis cutis ma hope.

ʻIke pinepine ʻia nā leona a puni nā manamana lima a me nā kuʻekuʻe lima a hāmama a hoʻokahe i kahi mea keʻokeʻo mānoanoa.

Kānāwai o ka calcinosis cutis

Ke hoʻoholo nei i ke ʻano o ka ʻoki ʻana o ka calcinosis āu i mea nui ai i ka hoʻoholo ʻana i ka lāʻau kūpono. E nānā ana kāu kauka iā ʻoe a lawe i kāu mōʻaukala olakino a nīnau iā ʻoe i nā nīnau e pili ana i kāu hōʻailona.

E kauoha paha ke kauka i kekahi mau hoʻokolohua keʻena hoʻokolohua e hoʻoholo ai i ke kumu kumu o kāu kalcisis cutis:

• nā ho'āʻo koko e ʻike ai inā kiʻekiʻe kiʻekiʻe kāu calcium a me nā phosphate, e nānā i nā māka no ka lupus a me nā hikoko hiki ʻole, a e hōʻoki i nā pae parathyroid a me nā pae vitamin D
• nā hoʻāʻo metabolic e kāpae i nā pilikia o ka hakuʻala
• X-ray, CT scans, a i ʻole scans iwi (scintigraphy) e nānā i ka nui o ka helu ʻana.
• biopsy o nā leona
• nā hoʻokolohua loea ʻē aʻe e nānā no dermatomyositis (kahi maʻi hōʻeha) a me nā maʻi maʻi waiū-alkali

ʻO kahi ʻenehana hou ma lalo o ka hoʻomohala ʻana e kōkua i ka ʻike diagnost is spectroscopy vibrational advanced. Hoʻohana kēia ʻano hana diagnostic iā Fourier transform infrared (FT-IR) a i ʻole Raman spectroscopic analysis. Hoʻomaopopo wikiwiki ia i ka hoʻohui kemika o nā lesion cutter cinosinosis. Hiki iā ia ke wānana i ka holomua o ka maʻi.

Hoʻomaʻamaʻa ʻana i nā kalesis cutis

ʻO ka mālama ʻana no ka make ʻana o ka calcinosis kaukaʻi ʻia i ka maʻi kumu a kumu paha.

Nā lāʻau

Hiki ke hoʻāʻo ʻia nā ʻano lāʻau like ʻole e mālama i nā leona, akā he spotty kā lākou kūleʻa.

No nā liona liʻiliʻi, nā lāʻau i hoʻopili ʻia:

• Warfarin
• ceftriaxone
• intravenous immunoglobulin (IVIG)

No nā liona nui aku, nā lāʻau i hoʻopili ʻia:

• diltiazem
• bisphosphonates
• probenecid
• aluminika hydroxide

Ua hōʻike ʻia kahi noiʻi ma 2003 i kahi hopena haʻahaʻa o ka lāʻau antibiotic minocycline i mea e hoʻomaha ai i ka ʻeha a me ka nui o nā liona i ka poʻe me ka maʻi CREST. He mea pono paha ka Topical sodium thiosulfate.

ʻOki kino

Inā ʻeha kou mau leona, maʻi pinepine, a hoʻopōʻino paha i kāu hana, hiki i kāu kauka ke koi i ke ʻoki. Akā e hoʻi hou paha nā leona ma hope o ke kaha ʻana. Paipai ʻia e hoʻomaka ke ʻōpala me kahi ʻāpana liʻiliʻi o kahi leona.

Nā lapaʻau ʻē aʻe

ʻO kahi lāʻau hou i hāpai ʻia ʻo ka hematopoietic stem cell transplantation (HSCT), kahi e pani ai i nā hunaola hana toto o ke kanaka. Ua hoʻohana ʻia kēia e mālama i kekahi mau maʻi autoimmune.

ʻO ka laser therapy a me ka lithotripsy nalu haʻalulu (kahi ultrasound therapy i hoʻohana ʻia e wāwahi ai nā pōhaku hakuʻala) he lāʻau lapaʻau kekahi.

ʻO Outlook no ka chicinosis cutis

ʻO ka nānā ʻana no nā kalciisis cutis kaukaʻi ʻia i ka maʻi a i ʻole ke kumu, a me ke koʻikoʻi o kāu mau leona. Hiki ke kōkua i nā kuʻuna o kēia manawa, a ke hoʻomohala ʻia nā mea hou. E kamaʻilio me kāu kauka e pili ana pehea e hoʻomaha ai i kāu mau hōʻailona a mālama i ke aʻa o ka pilikia.