ʻO nā kinikini Monoclonal: he aha ia a no ke aha lākou e kōkua ai i ka mālama ʻana i nā maʻi

Anter

• Nā laʻana o nā monopona monoclonal
• 1. ʻO Trastuzumab
• 2. ʻO Denosumab
• 3. ʻO Obinutuzumab
• 4. Ustequinumab
• 5. Pertuzumab
• Pehea e lawe ai i nā Antibodies Monoclonal

ʻO nā monoclonal antibodies he mau protein i hoʻohana ʻia e ka ʻōnaehana pale e ʻike ai a hoʻopau ʻole ai i nā kino o nā ʻāina ʻē, hiki ke loaʻa i nā koʻohune, nā mea ʻino a i ʻole nā ​​hunaola tumele He kikoʻī kēia mau protein, no ka mea, ʻike lākou i kahi pahuhopu kikoʻī, ka mea i kapa ʻia antigen, kahi e loaʻa i nā hunaola ʻē i ke kino. Hoʻomaopopo pehea e holo ai ka ʻōnaehana pale.

Hoʻokomo ʻia nā monoclonal antibodies, e like me denosumab, obinutuzumab a i ʻole ustequinumab, i loko o ke keʻena hoʻokolohua, ʻano like me nā mea i loaʻa i ke kino o ke kanaka, kahi e kōkua ai i ke kino e hakakā i kekahi mau maʻi. No laila, kaukaʻi ʻia i ka monoclonal antibody i hoʻohana ʻia, hiki ke hoʻohana ʻia kēia mau mea lapaʻau e mālama ai i kekahi mau maʻi koʻikoʻi e like me ka osteoporosis, leukemia, ka lāʻau psoriasis a i ʻole kekahi ʻano o ka maʻi ʻaʻai, e like me ka umauma a me ka maʻi ʻaʻa iwi.

Nā laʻana o nā monopona monoclonal

ʻO kekahi mau laʻana o nā monopona monoclonal me:

1. ʻO Trastuzumab

ʻO kēia antibody monoclonal, i kūʻai ʻia ma ke ʻano he Herceptin, i hoʻomohala ʻia e ka ʻenekinia genetile, a hoʻouka kaua kikoʻī i kahi protein i loaʻa i ka poʻe me kekahi maʻi maʻi ʻeha a me ka ʻōpū. No laila, hōʻike ʻia kēia lāʻau no ka mālama ʻana i ka maʻi ʻaʻai o ka umauma i kahi wā mua a i ʻole me ka metastasis a me ka maʻi ʻaʻai gastric i kahi pae holomua.

2. ʻO Denosumab

Kūʻai ʻia e like me Prolia a i ʻole Xgeva, aia i loko o kāna mea i hoʻohui ai ka monoclonal IgG2 antibody, nāna e hoʻopilikia i ka hana o kahi protein kikoʻī e hoʻoikaika ai nā iwi, e hoʻemi ana i nā manawa o ka haki. No laila, hōʻike ʻia ʻo Denosumab no ka mālama ʻana i ka nalo ʻana o ka iwi, osteoporosis, maʻi ʻaʻai iwi a i ʻole maʻi ʻaʻai i ka pae holomua me nā metastases iwi (i pāhola ʻia i nā iwi).

3. ʻO Obinutuzumab

ʻIke pū ʻia ʻo Gazyva, aia i loko o kāna antibodies i ʻike a hoʻopaʻa pono ʻia i ka protein CD20, i loaʻa ma luna o nā hunaola keokeo a i ʻole nā ​​lymphocytes B. No laila, hōʻike ʻia ka obinutuzumab no ka mālama ʻana i ka leukemia lymphocytic mau, ʻoiai hiki iā ia ke hōʻoki i ka ulu maʻamau o nā hunaola keokeo e kumu i kēia maʻi.

4. Ustequinumab

ʻIke ʻia kēia lāʻau ma ke ʻano kalepa e like me Stelara a haku ʻia e ka IgG1 monoclonal antibody kanaka, kahi e keʻakeʻa ai i nā protein i kuleana no ka hoʻokumu ʻana i ka psoriasis. No laila, hōʻike ʻia kēia lāʻau no ka mālama ʻana i ka plake psoriasis.

5. Pertuzumab

ʻIke pū ʻia ʻo Perjeta, haku ʻia ia i nā antibodies monoclonal e pili ana i ka mea ulu o ka epidermal factor 2 receptor, i loaʻa i kekahi mau maʻi ʻaʻai, e hoʻolohi nei a i ʻole ke kū nei i ko lākou ulu. No laila, ua hōʻike ʻia ʻo Perjeta no ka mālama ʻana i ka maʻi ʻaʻai umauma.

Pehea e lawe ai i nā Antibodies Monoclonal

Pono e lawe i nā lāʻau me Monoclonal Antibodies ma lalo o ke olakino olakino, ʻo ke ʻano o ka lāʻau e hoʻohana ai a ʻo nā lāʻau i manaʻo ʻia e pili i ka pilikia e mālama ʻia a me kona koʻikoʻi.

I ka hapanui o nā hihia, hoʻohana ʻia kēia mau hoʻoponopono i ka mālama ʻana i ka maʻi ʻaʻai, no ka mea he lāʻau antineoplastic ia e pono ai e hoʻohana ʻia e like me nā ʻōlelo kikoʻī i hāʻawi ʻia e ke kauka a pono e lawelawe ʻia i nā haukapila a i ʻole nā ​​keʻena lāʻau.