Antibiogram: pehea e hana ai a pehea e hoʻomaopopo ai i ka hopena
Anter
- Pehea e hana ai i ka antibiogram
- UrocULT me ka antibiogram
- Pehea e wehewehe ai i ka hopena
- No ke aha he mea pono e ʻike i ka antibiotic pololei?
ʻO ka antibiogram, i ʻike ʻia ʻo Antimicrobial Sensitivity Test (TSA), kahi hoʻāʻo e manaʻo ana e hoʻoholo i ka makaʻala a me ke kūʻē ʻana o ke koʻohune a me nā fungi i nā antibiotic. Ma o ka hopena o ka antibiogram, hiki i ke kauka ke kuhikuhi i nā antibiotic kūpono loa e mālama i ka maʻi o ke kanaka, a pēlā e hōʻalo ai i ka hoʻohana ʻana i nā antibiotic pono ʻole e hakakā ai i ka maʻi, me ka pale ʻana i ke kū ʻana o ke kūʻē.
ʻO ka maʻamau, hana ʻia ka antibiogram ma hope o ka ʻike ʻia o nā microorganism i nā nui i ke koko, mimi, nā feces a me nā aʻa. No laila, e like me ka microorganism i ʻike ʻia a me ka ʻike pilikino, hiki i ke kauka ke hōʻike i ka lāʻau kūpono kūpono loa.
Pehea e hana ai i ka antibiogram
No ka hoʻokō ʻana i ka antibiogram, e noi ke kauka i ka hōʻiliʻili o nā mea olaola e like me ke koko, ka mimi, ka ʻū, ka phlegm, nā feces a i ʻole nā hunaola mai ka meaola i hoʻohaumia ʻia e nā microorganism. Hoʻouna ʻia kēia mau laʻana i kahi keʻena hoʻokolohua microbiology no ka loiloi a me ka mahi ʻana i kahi moʻomeheu e makemake i ka ulu ʻana o ke koʻohune a i ʻole ka fungal.
Ma hope o ka ulu ʻana, hoʻokaʻawale ʻia ka microorganism a hāʻawi ʻia i nā hoʻokolohua ʻike e hiki ai i ka hopena o ka microorganism kuleana no ka maʻi. Ma hope o ka hoʻokaʻawale ʻana, hana pū ʻia ka antibiogram i mea e ʻike ʻia ai ka ʻike a me ke kūpale ʻana o ka microorganism i ʻike ʻia, a hiki ke hana ʻia i nā ala ʻelua:
- Antibiogram Diffusion Agar: I kēia kaʻina hana, waiho ʻia nā pāka pepa liʻiliʻi e loaʻa ana nā lāʻau ʻokoʻa ʻē aʻe i ka pā me ka moʻomeheu moʻomeheu kūpono no ka ulu ʻana o ka mea maʻi infectious. Ma hope o 1 a 2 mau lā i ka hale hoʻouluulu, hiki ke nānā a lohe paha ʻoe i ka ulu a puni ka diski. I ka loaʻa ʻole o ka ulu ʻana, ua ʻōlelo ʻia he maʻalahi ka microorganism i kēlā lāʻau ʻino, i manaʻo ʻia ʻo ia ka mea kūpono loa no ka mālama ʻana i ka maʻi;
- Pākuʻi uʻi hoʻoliʻiliʻi: i kēia kaʻina hana aia kahi ipu me nā dilutions o ka antibiotic me nā lāʻau ʻokoʻa, kahi e hoʻokau ʻia ai nā microorganism e nānā ʻia, a hoʻoholo ʻia ka Minimum Inhibitory Concentration (CMI) o ka lāʻau antibiotic. ʻO ka ipu kahi i mālama ʻole ʻia ai ka ulu microbial e kūlike i ka mahele lāʻau o ka lāʻau antibiotic e pono e hoʻohana ʻia i ka mālama ʻana, no ka mea, ua pale ʻia ka ulu ʻana o ka microorganism.
I kēia manawa i loko o nā keʻena hoʻokolohua, hoʻokō ʻia ka antibiogram e kahi hāmeʻa e hana ʻia ai nā hoʻokolohua kūʻē a me ka ʻike. Hōʻike ka hōʻike i hoʻokuʻu ʻia e nā lakohana e hōʻike ana i nā lāʻau ʻalopika i kūpale ʻia e ka mea maʻi infectious a he mea maikaʻi ia i ka hakakā ʻana i ka microorganism a me ke ʻano paʻa.
UrocULT me ka antibiogram
ʻO ka maʻi urinary tract kekahi o nā maʻi maʻamau i nā wahine, ka nui, a me nā kāne. No kēia kumu, he mea maʻamau no nā kauka e noi me ka hoʻohui o ka ʻano 1 mimi hoʻāʻo, ka EAS, a me ka moʻomeheu mimi me ka antibiogram. I kēia ala, hiki i ke kauka ke nānā inā aia kekahi loli i ka mimi e hōʻike ana i nā pilikia o ka puʻupaʻa, ma o EAS, a me ke kū ʻana o nā fungi a i ʻole nā koʻohune i ka maʻi urinary e hōʻike paha i ka maʻi, ma o ka moʻomeheu mimi.
Inā nānā ʻia ke alo o nā koʻohune i ka mimi, hana ʻia ka antibiogram ma hope e hiki ai i ke kauka ke ʻike i kahi antibiotic kūpono loa no ka mālama ʻana. Eia naʻe, i ka hihia o nā maʻi urinary, paipai wale ʻia ka lāʻau antibiotic ke loaʻa i nā kānaka nā ʻōuli e pale ai i ka ulu ʻana o ke kūpaʻa microbial.
Maopopo pehea e hana ai ka moʻomeheu mimi.
Pehea e wehewehe ai i ka hopena
Hiki i ka hopena o ka antibiogram ke kiʻi i 3 a 5 mau lā a loaʻa ʻia e ke kālailai ʻana i ka hopena o nā antibiotic i ka ulu ʻana o nā microorganism. ʻO ka lāʻau antibiotic e kāohi i ka ulu ʻana o microbial ka mea i hōʻike ʻia e mālama i ka maʻi, akā inā aia ka ulu ʻana, hōʻike ia ʻaʻole makaʻu ka microorganism i nīnau ʻia i kēlā antibiotic, ʻo ia hoʻi, kūpaʻa.
Pono e wehewehe i ka hopena o ka antibiogram e ke kauka, nāna e nānā i nā waiwai o ka Minimum Inhibitory Concentration, i kapa ʻia hoʻi ʻo CMI a i ʻole MIC, a me / a i ʻole ke anawaena o ka halo hoʻohiehie, kaukaʻi ʻia i ka hōʻike i hana ʻia. Kūlike ka IMC i ka palena iki o ka antibiotic i hiki ke kāohi i ka ulu microbial a kūlike me nā kūlana o ka ʻOihana Haumāna Haukino a me Laboratory, CLSI, a loli paha e like me ka antibiotic e hoʻāʻo a me ka microorganism i ʻike ʻia.
I ka hihia o ka agari diffusion antibiogram, kahi i waiho ʻia ai nā pepa i loaʻa kekahi mau concentrations o nā antibiotic i loko o ka moʻomeheu me ka microorganism, ma hope o ka hoʻoulu ʻana ma kahi o 18 mau hola e hiki ai ke ʻike i ke alo a i ʻole ka pāpā pāpā. Mai ka nui o ke anawaena o ka halos, hiki ke hōʻoia inā ʻaʻole maʻalahi ka microorganism, maʻalahi, waena a kūʻē paha i ka antibiotic.
Pono e wehewehe ʻia ka hopena ma muli o ka hoʻoholo ʻana o ka CLSI, ka mea e hoʻoholo ai no ka hoʻāʻo susceptibility o ka ʻO Escherichia coli iā Ampicillin, ʻo kahi laʻana, ʻo ka halo hoʻohaʻahaʻa ma lalo o a i ʻole 13 mm ka mea e hōʻike ana i ke kūpaʻa o ke koʻohune i ka lāʻau antibiotic a ʻo ka halo like a ʻoi aku paha ma mua o 17 mm e hōʻike ana he maʻalahi ka bacteria. E aʻo hou aʻe e pili ana i ka hopena o ka moʻomeheu mimi me ka antibiogram.
No laila, e like me ka hopena o ka antibiogram, hiki i ke kauka ke hōʻike i ka lāʻau antibiotic maikaʻi loa e hakakā ai i ka maʻi.
No ke aha he mea pono e ʻike i ka antibiotic pololei?
ʻO ka hoʻohana ʻana i nā lāʻau ʻalopika i kūpono ʻole a maikaʻi hoʻi no kahi microorganism e hoʻopaneʻe i ka hoʻōla o ke kanaka, mālama hapa i ka maʻi a makemake i ka hoʻomohala ʻana i nā mīkini microbial resistence, e ʻoi aku ka paʻakikī o ka mālama ʻana i ka maʻi.
No kēia kumu like, he mea nui ʻaʻole pono e hoʻohana i nā lāʻau ʻaloʻalo me ke alakaʻi ʻole a ke kauka a pono ʻole, ʻoiai e pau paha kēia i ke koho ʻana i nā microorganism e kūpaʻa hou aku i nā lāʻau ʻino, e hoʻemi ana i nā koho o nā lāʻau e hakakā i nā maʻi.