Ajovy (fremanezumab-vfrm)
Anter
- He aha ʻo Ajovy?
- ʻO kahi ʻano lāʻau hou
- Ka hoʻokō ʻana
- ʻO Generic Ajovy
- Hoʻohana ʻo Ajovy
- ʻO Ajovy no ka maʻi migraine
- Ka hopena no ka ulu poʻo poʻo
- Nā hopena ʻaoʻao ʻo Ajovy
- Nā hopena ʻaoʻao hou aʻe
- Nā hopena hopena koʻikoʻi
- Ka hopena hoʻowali
- Nā hopena ʻaoʻao lōʻihi
- Nā koho ʻē aʻe iā Ajovy
- Nā mea kūʻē CGRP
- ʻO Ajovy vs. nā lāʻau ʻē aʻe
- Ajovy vs. Aimovig
- ʻO Ajovy vs. Emgality
- Ajovy vs. Botox
- Kumukūʻai ʻo Ajovy
- Kōkua kālā
- ʻIkea Ajovy
- Nā ʻano lāʻau a me nā ikaika
- Nā hana no ka pale ʻana i ka maʻi migraine
- He aha inā e haʻo wau i kahi lāʻau?
- Pono wau e hoʻohana i kēia lāʻau lōʻihi?
- Pehea e lawe ai iā Ajovy
- Pehea e hoʻopili ai
- Manawa
- Lawe iā Ajovy me ka meaʻai
- Pehea e hana ai ʻo Ajovy
- Pehea ka lōʻihi o ka hana?
- Ajovy a me ka ʻalekohola
- Nā launa pū ʻo Ajovy
- ʻO Ajovy a me ka hāpai keiki
- Ajovy a me ka waiū hānai
- ʻO nā nīnau maʻamau e pili ana iā Ajovy
- Hiki iā Ajovy ke hoʻohana e mālama i ka maʻi migraine?
- Pehea ʻokoʻa ʻo Ajovy mai nā lāʻau migraine ʻē aʻe?
- Hoʻola ʻo Ajovy i ka huhū o ka migrain?
- Inā lawe wau iā Ajovy, hiki iaʻu ke oki i ka lawe ʻana i kaʻu mau lāʻau pale ʻē aʻe?
- ʻO overdose Ajovy
- Nā hōʻailona overdose
- He aha e hana ai inā he overdose
- Nā ʻōlelo aʻoaʻo a Ajovy
- Pau ʻo Ajovy
He aha ʻo Ajovy?
ʻO Ajovy kahi lāʻau lapaʻau inoa inoa inoa inoa e hoʻohana ʻia e pale i ka ulu ʻana o ka migraine i nā mākua. Hele mai ia me he syringe prefilled. Hiki iā ʻoe ke hoʻomoe iho iā Ajovy iā ʻoe iho, a i ʻole e loaʻa iā injection Ajovy mai kahi kauka olakino ma ke keʻena o kāu kauka. Hiki ke injected iā Ajovy i kēlā me kēia mahina a i kēlā me kēia hapahā makahiki (hoʻokahi manawa i kēlā me kēia ʻekolu mahina).
Aia i loko o Ajovy ka lāʻau fremanezumab, ka mea he monoclonal antibody. ʻO kahi antibody monoclonal kahi ʻano lāʻau i hana ʻia mai nā pūnaewele immune immune. Hana ia ma ka pale ʻana i kekahi o nā protein o kou kino mai ka holo ʻana. Hiki ke hoʻohana ʻia ʻo Ajovy i mea e pale aku ai i nā episodic a me nā migraine maʻi mau.
ʻO kahi ʻano lāʻau hou
ʻO Ajovy kahi ʻāpana o kahi papa lāʻau hou i ʻike ʻia ma ke ʻano he antagonists peptide (CGRP) e pili ana i ka ʻenemi helu. ʻO kēia mau lāʻau ka lāʻau mua i hana ʻia e pale i ka maʻi migraine.
Ua ʻae ka Food and Drug Administration (FDA) iā Ajovy i ka mahina ʻo Kepakemapa 2018. ʻO Ajovy ka lāʻau ʻelua i ka papa antagonist CGRP i ʻae ʻia e ka FDA e kōkua i ka pale ʻana i ka ulu o ka migraine.
Loaʻa ʻelua mau mea kūʻē CGRP ʻē aʻe. Kapa ʻia kēia mau lāʻau lapaʻau ʻo Emgality (galcanezumab) a me Aimovig (erenumab). Aia ka hā o ka CGRP antagonist i kapa ʻia ʻo eptinezumab ke aʻo ʻia nei nō hoʻi. Manaʻo ʻia e ʻae ʻia e ka FDA i ka wā e hiki mai ana.
Ka hoʻokō ʻana
No ke aʻo ʻana e pili ana i ka pono o Ajovy, e ʻike i ka ʻāpana ʻo "Ajovy e hoʻohana nei" ma lalo.
ʻO Generic Ajovy
Loaʻa ʻo Ajovy ma ke ʻano he lāʻau lapaʻau inoa. ʻAʻole i loaʻa i kēia manawa i ka palapala generic.
Aia ʻo Ajovy i ka lāʻau fremanezumab, i kapa ʻia hoʻi ʻo fremanezumab-vfrm. ʻO ke kumu "-vfrm" ʻike ʻia ma ka hopena o ka inoa e hōʻike i ka ʻokoʻa o ka lāʻau mai nā lāʻau like e hana ʻia i ka wā e hiki mai ana. Kapa ʻia nā inoa ʻē aʻe i nā antibodies monoclonal i kahi ala like.
Hoʻohana ʻo Ajovy
Ua ʻae ka US Food and Drug Administration (FDA) i nā lāʻau i kuhikuhi ʻia e like me Ajovy e mālama a pale paha i kekahi mau ʻano.
ʻO Ajovy no ka maʻi migraine
Ua ʻae ʻo FDA iā Ajovy e kōkua i ka pale ʻana i ka ulu ʻana o ka ulu o ka ulu ma nā mākua. Kūpilikiʻi kēia mau poʻo poʻo. ʻO lākou nō ka hōʻailona nui o ka migraine, kahi ʻano neurological. ʻO ka maʻalahi i ka mālam a me ke kani, ka paupau, ka luaʻi, a me ka pilikia e ʻōlelo ʻana he mau hōʻailona ʻē aʻe i hiki ke kū ʻia me ka ʻeha migraine.
Ua ʻae ʻia ʻo Ajovy e pale aku i nā kuʻina o ka migraine mau loa a me nā poʻo hina episodic. Ua haʻi ka International Headache Society i ka poʻe i loaʻa i ka episodic migraine headache ʻike ma lalo o 15 migraine a i ʻole headache lā i kēlā me kēia mahina. ʻO ka poʻe i loaʻa i ka maʻi migraine maʻi mau, ma ka ʻaoʻao ʻē aʻe, ʻike i 15 mau lā a ʻoi paha mau lā headache i kēlā me kēia mahina ma kahi o 3 mau mahina. A ma ka liʻiliʻi he 8 o kēia mau lā he mau lā migraine.
Ka hopena no ka ulu poʻo poʻo
Ua ʻike ʻia ka maikaʻi o Ajovy no ka pale ʻana i ka maʻi migraine. No ka ʻike e pili ana i ka hana a Ajovy i ka noiʻi maʻi, e ʻike i ka ʻike o ka lāʻau.
Paipai ka American Headache Society i ka hoʻohana ʻana o Ajovy e pale aku ai i ka ʻeha o ka migraine i nā mākua i hiki ʻole ke hōʻemi i ko lākou helu o nā lā migraine i lawa me nā lāʻau ʻē aʻe. Paipai pū kekahi iā Ajovy no ka poʻe hiki ʻole ke lawe i nā lāʻau lapaʻau pale pale migraine ʻē aʻe ma muli o nā hopena a i ʻole ka launa ʻana o ka lāʻau.
Nā hopena ʻaoʻao ʻo Ajovy
Hiki iā Ajovy ke hana i nā hopena ʻoluʻolu a koʻikoʻi paha. Loaʻa i ka papa inoa aʻe kekahi o nā hopena ʻaoʻao nui i hiki ke hana ʻia i ka wā e lawe ana iā Ajovy. ʻAʻole pili kēia papa inoa i nā hopena ʻē aʻe āpau.
No ka ʻike hou aku e pili ana i nā hopena ʻē aʻe o Ajovy, a i ʻole nā ʻōlelo aʻoaʻo e pili ana i ka hopena me ka hopena pilikia, e kamaʻilio me kāu kauka a kauka paha.
Nā hopena ʻaoʻao hou aʻe
ʻO nā hopena ʻaoʻao maʻamau o Ajovy nā hopena o ka pūnaewele injection. Hiki i kēia ke hoʻopili i nā hopena aʻe ma ka pūnaewele kahi e hoʻopili ai i ka lāʻau.
- ʻulaʻula
- ʻumeʻume
- ʻeha
- palupalu
ʻAʻole paʻakikī a kūmau mau paha nā hopena o ka pūnaewele injection. E nalo paha ka hapa nui o kēia mau hopena i loko o nā lā ʻelua a i ʻole kekahi mau pule. E kamaʻilio me kāu kauka a kauka paha inā ʻoi aku ke koʻikoʻi o kāu hopena a i ʻole hele aku.
Nā hopena hopena koʻikoʻi
ʻAʻole maʻamau ka loaʻa ʻana o nā hopena koʻikoʻi mai Ajovy, akā hiki nō. ʻO ka hopena koʻikoʻi koʻikoʻi o Ajovy kahi hopena maʻi maʻi i ka lāʻau. E nānā ma lalo no nā kikoʻī.
Ka hopena hoʻowali
E like me ka nui o nā lāʻau, hiki i kekahi poʻe ke ʻike i kahi hopena maʻi ma hope o ka lawe ʻana iā Ajovy. ʻO nā ʻōuli o kahi hopena maʻi ʻaʻano haʻahaʻa e hoʻopili pū paha:
- ʻumeʻume
- ʻāwīwī o ka ʻili
- flushing (hoʻomehana a ʻulaʻula i kou ʻili)
Kākaʻikahi ka hopena o ka maʻi ahonui i Ajovy. ʻO nā hōʻailona kūpono o ka hopena maʻi ʻaʻai nui e komo pū me:
- pehu o kou alelo, waha, a ʻāʻī paha
- angioedema (hāhā ma lalo o kou ʻili, maʻamau i kou mau lihilihi, nā lehelehe, nā lima, a me nā wāwae)
- pilikia hanu
Inā loaʻa iā ʻoe kahi hopena maʻi ʻeha iā Ajovy, e kāhea koke aku i kāu kauka. Inā manaʻo kou mau ʻōuli hoʻoweliweli i ke ola a i ʻole inā manaʻo ʻoe e loaʻa ana kahi pilikia olakino, kāhea iā 911.
Nā hopena ʻaoʻao lōʻihi
ʻO Ajovy kahi lāʻau i ʻāpono hou ʻia i kahi papa hou o nā lāʻau. ʻO ka hopena, aia kahi noiʻi lōʻihi lōʻihi loa no ka palekana o Ajovy, a ʻaʻole ʻike iki ʻia e pili ana i nā hopena lōʻihi. ʻO ka loiloi loiloi lōʻihi loa (PS30) o Ajovy i hala i hoʻokahi makahiki, a ʻaʻole hōʻike ka poʻe i ke aʻo ʻana i nā hopena ʻē aʻe koʻikoʻi.
ʻO ka hopena o ka pūnaewele injection ka hopena maʻamau i hōʻike ʻia i loko o ka hoʻopaʻa makahiki. Ua hōʻike ka poʻe i nā hopena aʻe i ka wahi i hāʻawi ʻia i ka injection.
- ʻeha
- ʻulaʻula
- kahe ana ke koko
- ʻumeʻume
- ʻili hāpuʻupuʻu a i hāpai ʻia paha
Nā koho ʻē aʻe iā Ajovy
Loaʻa nā lāʻau ʻē aʻe i hiki ke kōkua i ka pale ʻana i ka maʻi migraine. Ua kūpono paha kekahi no ʻoe ma mua o kekahi. Inā makemake ʻoe e ʻike i kahi ʻē aʻe iā Ajovy, e kamaʻilio me kāu kauka. Hiki iā lākou ke kōkua iā ʻoe e aʻo e pili ana i nā lāʻau ʻē aʻe i kūpono iā ʻoe.
Eia kekahi mau laʻana o nā lāʻau ʻē aʻe a ka FDA i ʻae ai e pale aku i ka ulu ʻana o ka ulu o ka migraine.
- ka beta-blocker propranolol (Inderal, Inderal LA)
- ka neurotoxin onabotulinumtoxinA (Botox)
- kekahi mau lāʻau hopu, e like me divalproex sodium (Depakote) a i ʻole topiramate (Topamax, Trokendi XR)
- nā peptide (CGRP) pili pili pū kekahi i ka calcitonin: erenumab-aooe (Aimovig) a me galcanezumab-gnlm (Emgality)
Eia kekahi mau laʻana o nā lāʻau ʻē aʻe i hiki ke hoʻohana ʻia i ka lepili hōʻailona no ka pale ʻana i ka maʻi migraine.
- kekahi mau lāʻau hopu, e like me ka valproate sodium
- kekahi mau antidepressants, e like me amitriptyline a i ʻole venlafaxine (Effexor XR)
- kekahi beta-blockers, e like me metoprolol (Lopressor, Toprol XL) a i atenolol (Tenormin)
Nā mea kūʻē CGRP
ʻO Ajovy kahi ʻano lāʻau hou i kapa ʻia he antagonist peptide (CGRP) pili pili i ka ʻaoʻao. I ka 2018, ua ʻae ʻo FDA iā Ajovy e pale i ka maʻi migraine, a me ʻelua mau mea kūʻē CGRP ʻē aʻe: Emgality a me Aimovig. E manaʻo ʻia e ʻāpono koke ʻia kahi lāʻau ʻehā (eptinezumab).
Pehea lākou e hana ai
ʻO nā mea ʻekolu CGRP antagonists i loaʻa i kēia manawa e hana nei i nā ʻano ʻokoʻa iki e kōkua ai i ka pale ʻana i ka ulu o ka migraine.
ʻO ka CGRP kahi protein i kou kino. Ua hoʻopili ʻia me ka vasodilation (hoʻonui ʻia o nā kīʻaha koko) a me ka mumū i ka lolo, kahi e hopena ai i ka ʻeha ʻeha o ka migraine. I mea e hopena ai kēia mau hopena i ka lolo, pono i ka CGRP e hoʻopaʻa (hoʻopili) i kāna mau mea loaʻa. ʻO nā mea loaʻa nā mole i nā paia o nā hunaola o kou lolo.
Hana ʻo Ajovy a me Emgality i ka hoʻopili ʻana i ka CGRP. Pale kēia i ka CGRP mai ka hoʻopili ʻana i kāna mau receptor. ʻO Aimovig, ma ka ʻaoʻao ʻē aʻe, hana ma ka hoʻopili ʻana i nā mea loaʻa iā lākou iho. Mālama kēia i ka CGRP mai ka hoʻopili ʻana iā lākou.
I ka pale ʻana iā CGRP mai ka hoʻopili ʻana i kāna mea loaʻa, kōkua kēia mau lāʻau ʻekolu i ka pale ʻana i ka vasodilation a me ka mumū. A ʻo kahi hopena, hiki iā lākou ke pale i ka hōʻeha o ka migraine.
ʻAoʻao ma ka ʻaoʻao
Hoʻohālikelike kēia pakuhi i kekahi mau ʻike e pili ana iā Aimovig, Ajovy, a me Emgality. ʻO kēia mau lāʻau lapaʻau he ʻekolu CGRP antagonists i ʻae ʻia i kēia manawa e kōkua i ka pale ʻana i ka maʻi migraine. (E aʻo hou ai e pili ana i ka hoʻohālikelike ʻana o Ajovy me kēia mau lāʻau, e ʻike i ka ʻāpana "Ajovy vs. nā lāʻau ʻē aʻe" ma lalo.)
ʻO Ajovy | ʻAimovig | Emgality | |
ʻO ka lā ʻae no ka pale ʻana i ka maʻi migraine | Kepakemapa 14, 2018 | Mei 17, 2018 | Kepakemapa 27, 2018 |
Mea hoʻohui lāʻau | Fremanezumab-vfrm | Erenumab-aooe | Galcanezumab-gnlm |
Pehea e lawelawe ai | Hoʻokomo ʻia iho ʻo Subcutaneous i kahi syringe i hoʻomākaukau ʻia | Subcutaneous iho-injection me ka hoʻohana 'ana i prefilled autoinjector | Subcutaneous iho-injection ka hoʻohana 'ana i ka prefilled pen a syringe |
Hana | Mahina a i ʻole ʻekolu mahina | Mahina | Mahina |
Pehea e hana ai | Kāohi ʻia nā hopena a CGRP e ka nakinaki ʻana iā CGRP, ka mea e ālai iā ia mai ka hoʻopili ʻana i ka mea loaʻa iā CGRP | Kāohi i nā hopena o CGRP e ka pale ʻana i ka mea loaʻa iā CGRP, ka mea e pale aku iā CGRP mai ka hoʻopili ʻana iā ia | Kāohi ʻia nā hopena a CGRP e ka nakinaki ʻana iā CGRP, ka mea e ālai iā ia mai ka hoʻopili ʻana i ka mea loaʻa iā CGRP |
Kālā * | $ 575 / mahina a i ʻole $ 1,725 / hapahā | $ 575 / mahina | $ 575 / mahina |
* Hiki ke hoʻololi i nā kumukūʻai ma muli o kāu wahi, ka hale kūʻai lāʻau i hoʻohana ʻia, kāu uhi ʻinikua, a me nā polokalamu kōkua mea hana.
ʻO Ajovy vs. nā lāʻau ʻē aʻe
Mahalo paha ʻoe pehea e hoʻohālikelike ai ʻo Ajovy i nā lāʻau ʻē aʻe i kuhikuhi ʻia no nā hoʻohana like. Ma lalo nā hoʻohālikelike ma waena o Ajovy a me kekahi mau lāʻau.
Ajovy vs. Aimovig
Aia i loko o Ajovy ka lāʻau fremanezumab, ka mea he monoclonal antibody. Aia ʻo Aimovig i ka erenumab, a he monoclonal antibody kekahi. ʻO nā monoclonal antibodies nā lāʻau i hana ʻia mai nā pūnaewele ʻōnaehana pale. Hoʻopaʻa lākou i ka hana o kekahi mau protein i kou kino.
Hana ʻo Ajovy a me Aimovig i nā ʻano ʻokoʻa iki. Eia nō naʻe, ua kāohi lāua ʻelua i ka hana o kahi protein i kapa ʻia ʻo ka peptide pili i ka ʻenekene kalipona (CGRP). Hana ʻo CGRP i ka vasodilation (hoʻonui ʻia o nā kīʻaha koko) a me ka mumū i ka lolo. Hiki i kēia hopena ke hopena i ka ulu poʻo o ka migraine.
Ma ka pale ʻana iā CGRP, Ajovy a me Aimovig kōkua i ka pale ʻana i ka vasodilation a me ka mumū. Hiki paha i kēia ke kōkua i ka pale ʻana i ka maʻi migraine.
Hoʻohana
Ua ʻae ʻia ʻo Ajovy lāua ʻo Aimovig e pale aku i ka ʻeha o ka migraine i nā mākua.
Nā ʻano a me ka hoʻokele
Hele mai nā lāʻau Ajovy a me Aimovig ma ke ʻano o ka hoʻopili ʻana i hāʻawi ʻia ma lalo o kou ʻili (subcutaneite). Hiki iā ʻoe ke hoʻopili i nā lāʻau iā ʻoe iho ma ka home. Hiki i nā lāʻau ʻelua ke hoʻopili iā ʻoe iho i ʻekolu mau wahi: ka mua o kou mau ʻūhā, ke kua o kou mau lima luna, a i ʻole kou ʻōpū.
Hele mai ʻo Ajovy i ke ʻano o kahi syringe i hoʻomākaukau ʻia me kahi lāʻau hoʻokahi. Hiki ke hāʻawi ʻia iā Ajovy ma ke ʻano he hoʻokahi injection o 225 mg i hoʻokahi manawa i ka mahina. Ma ke ʻano he koho ʻē aʻe, hiki ke hāʻawi ʻia ma ke ʻano he ʻekolu injection o 675 mg e lawelawe ʻia i kēlā me kēia hapahā makahiki (hoʻokahi manawa i kēlā me kēia ʻekolu mahina).
Hele mai ʻo Aimovig ma ke ʻano o kahi autoinjector i hoʻomākaukau ʻia me kahi lāʻau hoʻokahi. Hāʻawi pinepine ʻia ma ke ʻano he 70-mg injection i hoʻokahi manawa i ka mahina. Akā ʻoi aku ka maikaʻi o kahi maʻa 140-mg mahina no kekahi poʻe.
Nā hopena a me nā pilikia
Hana like ʻo Ajovy a me Aimovig i nā ala like a no laila ke kumu o kekahi o nā hopena ʻaoʻao like. Hoʻokumu pū lākou i kekahi i nā hopena ʻokoʻa.
Nā hopena ʻaoʻao hou aʻe
Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻē aʻe i hiki ke hana ʻia me Ajovy, me Aimovig, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).
- Hiki ke hana me Ajovy:
- ʻaʻohe kū hoʻokahi hopena ʻaoʻao
- Hiki ke hana me Aimovig:
- kōpaʻa
- ʻūpī mākala a i ʻole nā spasms
- ʻo nā maʻi hanu luna e like me ke anuanu a i ʻole nā maʻi sinus
- nā ʻōuli like flu
- ʻeha kua
- Hiki ke hana me Ajovy a me Aimovig:
- ʻO nā hopena o ka pūnaewele injection e like me ka ʻeha, ʻili, a ʻulaʻula paha
Nā hopena hopena koʻikoʻi
ʻO ka hopena koʻikoʻi koʻikoʻi no Ajovy a me Aimovig kahi hopena maʻi maʻi nui. ʻAʻole maʻamau kēlā ʻano hopena, akā hiki nō naʻe. (No ka ʻike hou aku, e ʻike i ka "Allergic react" ma ka ʻāpana "Ajovy effects" ma luna).
Hopena Immune
I nā hoʻokolohua hoʻokolohua no nā lāʻau ʻelua, ua ʻike ka hapa liʻiliʻi o ka poʻe i ka hopena pale. Ua hana kēia hopena i ko lākou kino e hoʻomohala i nā mea pale kūʻē iā Ajovy a i ʻole Aimovig.
ʻO nā Antibodies nā protein i loko o ka ʻōnaehana pale e hoʻouka i nā mea haole i kou kino. Hiki i kou kino ke hana i nā antibodies i kekahi mea haole. Hoʻopili kēia i nā meaola monoclonal. Inā hana kou kino i nā mea ʻino iā Ajovy a i ʻole Aimovig, ʻaʻole holo pono paha ka lāʻau iā ʻoe. Akā e hoʻomanaʻo no ka mea i ʻae ʻia ʻo Ajovy a me Aimovig i ka makahiki 2018, ua hiki wawe loa ka ʻike ʻana i ka hopena o kēia hopena a pehea e hoʻopili ai i ka hoʻohana ʻana o ka poʻe i kēia mau lāʻau i ka wā e hiki mai ana.
Ka hoʻokō ʻana
ʻAʻole i hoʻohālikelike pololei ʻia kēia mau lāʻau i ka hoʻokolokolo hoʻokolohua. Eia nō naʻe, ua ʻike ʻia nā noiʻi i nā Ajovy a me Aimovig e kūleʻa i ka pale ʻana i nā episodic a me nā migraine maʻi mau.
Hoʻohui ʻia, paipai nā kulekele lāʻau migraine i kekahi lāʻau e like me ke koho no kekahi poʻe. Hoʻopili kēia i ka poʻe i hiki ʻole ke hōʻemi i ko lākou mau lā migraine o ka mahina e lawa me nā lāʻau ʻē aʻe. Hoʻopili pū lākou i ka poʻe hiki ʻole ke hoʻomanawanui i nā lāʻau ʻē aʻe ma muli o nā hopena a i ʻole ka launa ʻana o ka lāʻau.
Nā kumukūʻai
Hiki ke loli ke kumukūʻai o Ajovy a i ʻole Aimovig ma muli o kāu hoʻolālā mālama. E hoʻohālikelike i nā kumukūʻai no kēia mau lāʻau, e nānā iā GoodRx.com. ʻO ke kumukūʻai maoli āu e uku ai no kekahi o kēia mau lāʻau e pili ana i kāu hoʻolālā ʻinikua, kou wahi, a me ka hale kūʻai āu e hoʻohana ai.
ʻO Ajovy vs. Emgality
Aia ʻo Ajovy i ka fremanezumab, kahi he monoclonal antibody. Loaʻa i ka Emgality galcanezumab, a he monoclonal antibody kekahi. ʻO kahi antibody monoclonal kahi ʻano lāʻau i hana ʻia mai nā pūnaewele ʻōnaehana pale. Hoʻomaha ia i ka hana o kekahi mau protein i kou kino.
Hoʻomaha ʻo Ajovy a me Emgality i ka hana o ka helu helu e pili ana i ka peptide (CGRP) e pili ana i ka ʻohana. ʻO ka CGRP kahi protein i kou kino. Kuhi ia i ka vasodilation (hoʻonui ʻia o nā kīʻaha koko) a me ka mumū i ka lolo, kahi e hopena ai i ka ʻeha o ka migraine.
Ma ka hoʻōki ʻana iā CGRP mai ka hana ʻana, kōkua ʻo Ajovy a me Emgality i ka pale ʻana i ka vasodilation a me ka mumū ma ka lolo. Hiki paha i kēia ke kōkua i ka pale ʻana i ka maʻi migraine.
Hoʻohana
Ua ʻae ʻia ʻo Ajovy a me Emgality e ʻākoʻo ʻia e FDA e pale i ka ulu ʻana o ka ulu o ka migraine i nā mākua.
Nā ʻano a me ka hoʻokele
Hele mai ʻo Ajovy i ke ʻano o kahi syringe i hoʻomākaukau ʻia me kahi lāʻau hoʻokahi. Hele mai ka Emgality i ke ʻano o ka syringe prefilled a i ʻole ka peni.
Hoʻokomo ʻia nā lāʻau ʻelua ma lalo o kou ʻili (subcutaneous). Hiki iā ʻoe ke hoʻomoe iho iā Ajovy a me Emgality ma ka home.
Hiki iā injovy ke hōʻeha iā ia iho me ka hoʻohana ʻana i hoʻokahi o nā ʻokoʻa ʻelua. Hiki ke hāʻawi ʻia ma ke ʻano he hoʻokahi injection o 225 mg hoʻokahi manawa i kēlā me kēia mahina, a i ʻole ʻekolu mau ʻoki ʻokoʻa (no ka nui o 675 mg) hoʻokahi manawa i kēlā me kēia ʻekolu mahina. E koho kāu kauka i ka manawa kūpono nāu.
Hāʻawi ʻia ʻo Emgality ma ke ʻano he hoʻokahi injection o 120 mg, hoʻokahi manawa i kēlā me kēia mahina. (ʻO ka mahele o ka mahina mua loa kahi mahele lāʻau ʻelua inika nui e ʻākoakoa ana he 240 mg.)
Hiki i nā Ajovy a me Emgality ke hoʻopili ʻia i ʻekolu mau wahi kūpono: ka mua o kou mau ʻūhā, ke kua o kou mau lima luna, a i ʻole kou ʻōpū. Hoʻohui ʻia, hiki i ka Emgality ke hoʻopili ʻia i loko o kou mau puʻupuʻu.
Nā hopena a me nā pilikia
ʻO Ajovy a me Emgality nā lāʻau like loa a hoʻohālikelike i nā hopena like a me nā ʻaoʻao ʻē aʻe.
Nā hopena ʻaoʻao hou aʻe
Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻē aʻe i hiki ke hana ʻia me Ajovy, me Emgality, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).
- Hiki ke hana me Ajovy:
- ʻaʻohe kū hoʻokahi hopena ʻaoʻao
- Hiki ke hana me Emgality:
- ʻeha kua
- maʻi maʻi hanu
- eha ka 'ā'ī
- maʻi lele
- Hiki ke hana me Ajovy a me Emgality:
- ʻO nā hopena o ka pūnaewele injection e like me ka ʻeha, ʻili, a ʻulaʻula paha
Nā hopena hopena koʻikoʻi
ʻO kahi hopena maʻi ʻino ka hopena nui a koʻikoʻi no Ajovy a me Emgality. ʻAʻole maʻamau ka loaʻa ʻana o kēlā ʻano hopena, akā hiki nō. (No ka ʻike hou aku, e ʻike i ka "Allergic react" ma ka ʻāpana "Ajovy effects" ma luna).
Hopena Immune
I nā hoʻokolohua hoʻokolohua ʻokoʻa no nā lāʻau Ajovy a me Emgality, kahi hapa iki o ka poʻe i ʻike i ka hopena pale. Ua hana kēia hopena pale i ko lākou mau kino e hana i nā mea pale kūʻē i nā lāʻau.
ʻO nā Antibodies nā protein immune system e hoʻouka i nā mea haole i kou kino. Hiki i kou kino ke hana i nā mea pale i nā mea haole. Hoʻopili kēia i nā meaola monoclonal e like me Ajovy a me Emgality.
Inā hana kou kino i nā mea ʻae i Ajovy a i ʻole Emgality, ʻaʻole holo pono paha kēlā lāʻau iā ʻoe.
Eia nō naʻe, hikiwawe loa ia e ʻike i ke ʻano maʻamau o kēia hopena no ka mea ua ʻae ʻia ʻo Ajovy a me Emgality i ka makahiki 2018. ʻO ka hikiwawe loa nō hoʻi ia e ʻike pehea e hiki ai i ka hopena ke hoʻohana ka poʻe i kēia mau lāʻau ʻelua i ka wā e hiki mai ana.
Ka hoʻokō ʻana
ʻAʻole i hoʻohālikelike pololei ʻia kēia mau lāʻau i ka hoʻokolokolo hoʻokolohua. Eia nō naʻe, ua ʻike ʻia nā noiʻi ma nā Ajovy a me Emgality e maikaʻi i ka pale ʻana i nā episodic a me nā migraine maʻi mau.
Hoʻohui ʻia, paipai ʻia nā Ajovy a me Emgality e nā alakaʻi alakaʻi no ka poʻe hiki ʻole ke lawe i nā lāʻau ʻē aʻe ma muli o nā hopena a i ʻole nā launa ʻana o ka lāʻau. Paipai pū ʻia lākou no ka poʻe hiki ʻole ke hōʻemi i kā lākou helu o ka ulu nui o ka migraine i kēlā me kēia mahina e lawa me nā lāʻau ʻē aʻe.
Nā kumukūʻai
Hiki ke loli ke kumukūʻai o Ajovy a i ʻole Emgality ma muli o kāu hoʻolālā mālama. E hoʻohālikelike i nā kumukūʻai no kēia mau lāʻau, e nānā iā GoodRx.com. ʻO ke kumukūʻai maoli āu e uku ai no kekahi o kēia mau lāʻau e pili ana i kāu hoʻolālā ʻinikua, kou wahi, a me ka lāʻau kūʻai āu e hoʻohana ai.
Ajovy vs. Botox
Aia ʻo Ajovy i ka fremanezumab, kahi he monoclonal antibody. ʻO kahi antibody monoclonal kahi ʻano lāʻau i hana ʻia mai nā pūnaewele ʻōnaehana pale. Kōkua ʻo Ajovy i ka pale ʻana i ka ulu o ka migraine ma o ka hoʻokuʻi ʻana i ka hana o kekahi mau protein e hoʻonāuki i ka migraines.
ʻO ka mea hana lāʻau nui ma Botox ka onabotulinumtoxinA. ʻO kēia lāʻau lapaʻau he ʻāpana o ka papa o nā lāʻau i ʻike ʻia e like me neurotoxins. Hana ʻo Botox i ka palaki ʻana i nā mākala no loko o ia manawa i injected. Mālama kēia hopena i nā mākala i nā hōʻailona ʻeha mai ka hoʻololi ʻana. Manaʻo ʻia he kōkua kēia hana i ka pale ʻana i ka huhū o ka migraine ma mua o ka hoʻomaka ʻana.
Hoʻohana
Ua ʻae ʻo FDA iā Ajovy e pale i ka maʻi migraine maʻi mau a episodic paha i nā mākua.
Ua ʻae ʻia ʻo Botox i mea e pale aku ai i nā poʻo o ka migraine mau i nā mākua. Ua ʻae ʻia ʻo Botox e mālama i nā ʻano he nui, e like me:
- spasticity mānoanoa
- ʻōpū hū
- sweating nui loa
- cerny dystonia (ʻeha ʻeha wili)
- ʻōniu maka
Nā ʻano a me ka hoʻokele
Hele mai ʻo Ajovy ma ke ʻano he syringe ma kahi lāʻau hoʻokahi. Hāʻawi ʻia ia ma ke ʻano he injection i lalo o kou ʻili (subcutaneous) hiki iā ʻoe ke hāʻawi iā ʻoe iho ma ka home, a i ʻole ke hāʻawi aku kahi mea mālama iā ʻoe ma ke keʻena o kāu kauka.
Hiki ke hāʻawi ʻia iā Ajovy i hoʻokahi o nā manawa ʻokoʻa ʻelua: hoʻokahi injection 225-mg i hoʻokahi manawa i kēlā me kēia mahina, a i ʻole ʻekolu mau ʻoki ʻokoʻa (ka nui o 675 mg) hoʻokahi manawa i kēlā me kēia ʻekolu mahina. E koho kāu kauka i ka manawa kūpono nāu.
Hiki iā injovy ke hoʻopili ʻia i ʻekolu mau wahi kūpono: ka mua o kou mau ʻūhā, ke kua o kou mau lima kiʻekiʻe, a i ʻole kou ʻōpū.
Hāʻawi pū ʻia ʻo Botox ma ke ʻano he injection, akā hāʻawi mau ʻia ia ma ke keʻena o ke kauka. Hoʻokomo ʻia ia i loko o kahi mākala (intramuscular), maʻa mau i kēlā me kēia 12 pule.
ʻO nā pūnaewele kahi e hoʻopili pinepine ʻia ai ʻo Botox e hoʻopili ʻia ma kou lae, ma luna a kokoke i kou mau pepeiao, kokoke i kāu kaula lauoho ma ke kumu o kou ʻāʻī, a ma ka hope o kou ʻāʻī a me kou poʻohiwi. I kēlā me kēia kipa, e hāʻawi mau kāu kauka iā ʻoe i 31 mau injection liʻiliʻi i kēia mau wahi.
Nā hopena a me nā pilikia
Hoʻohana ʻia ʻo Ajovy a me Botox i mea e pale aku ai i ka maʻi migraine, akā hana lākou i nā ʻano ʻokoʻa o ke kino. No laila, loaʻa iā lākou kekahi mau hopena ʻaoʻao like, a me kekahi ʻokoʻa.
Nā hopena ʻaoʻao hou aʻe
Loaʻa i kēia mau papa inoa nā laʻana o nā hopena ʻino e hiki ke hana ʻia me Ajovy, me Botox, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).
- Hiki ke hana me Ajovy:
- kekahi mau hopena ʻaoʻao maʻamau
- Hiki ke hana me Botox:
- nā ʻōuli like flu
- ʻeha poʻo ʻeha a ʻehaʻeha loa paha ka ʻeha o ka migraine
- ʻōlohelohe maka
- lolo palaka
- ʻeha ʻāʻī
- ʻoʻoleʻa o ka mākala
- ʻehaʻeha a me nāwaliwali
- Hiki ke hana me nā Ajovy a me Botox:
- nā hopena kahua pūnaewele injection
Nā hopena hopena koʻikoʻi
Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻino e hiki ke hana ʻia me Ajovy, me Xultophy, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).
- Hiki ke hana me Ajovy:
- kekahi mau hopena koʻikoʻi koʻikoʻi
- Hiki ke hana me Botox:
- ka palahalaha ʻana o ka maʻi lōlō i nā mākala kokoke *
- pilikia i ka ale ʻana a me ka hanu ʻana
- maʻi kūpilikiʻi
- Hiki ke hana me nā Ajovy a me Botox:
- hopena hopena maikaʻi
* ʻO Botox kahi ʻōlelo aʻoaʻo mai ka FDA no ka hoʻolaha ʻana o ka maʻi lōlō i nā io kokoke e pili ana i ka ʻume. ʻO kahi ʻōlelo aʻoaʻo i pahu ʻia ka ʻōlelo aʻo ikaika a ka FDA e koi ai. Hoʻomaopopo ia i nā kauka a me nā mea maʻi e pili ana i nā hopena lāʻau e weliweli paha.
Ka hoʻokō ʻana
ʻO nā headache migren maʻi ka maʻi wale nō i hoʻohana ʻia ʻo Ajovy a me Botox e pale ai.
Paipai nā kulekele lapaʻau iā Ajovy ma ke ʻano he koho kūpono no ka poʻe hiki ʻole ke hōʻemi i kā lākou helu o ka ulu nui o ka migraine me nā lāʻau ʻē aʻe. Paipai pū ʻia ʻo Ajovy no ka poʻe hiki ʻole ke hoʻomanawanui i nā lāʻau ʻē aʻe ma muli o kā lākou hopena a i ʻole ka launa ʻana o ka lāʻau.
Kākoʻo ka American Academy of Neurology iā Botox ma ke ʻano he koho lapaʻau no ka poʻe me ka maʻi migraine maʻi mau.
ʻAʻole hoʻohālikelike pololei nā noiʻi maʻi i ka pono o Ajovy a me Botox. Akā ua hōʻike ʻokoʻa nā noiʻi ʻelua i ka Ajovy a me ka Botox i mea e kōkua maikaʻi ai i ka pale ʻana i ka maʻi migraine mau.
Nā kumukūʻai
E loli paha ke kumukūʻai o Ajovy a i ʻole Botox e like me kāu hoʻolālā mālama. E hoʻohālikelike i nā kumukūʻai no kēia mau lāʻau, e nānā iā GoodRx.com. ʻO ke kumukūʻai maoli āu e uku ai no kekahi o kēia mau lāʻau e pili ana i kāu hoʻolālā ʻinikua, kou wahi, a me ka hale kūʻai āu e hoʻohana ai.
Kumukūʻai ʻo Ajovy
E like me nā lāʻau āpau, hiki ke hoʻololi i nā kumukūʻai no Ajovy.
E hilinaʻi kāu kumukūʻai maoli i kāu uhi ʻinikua, kou wahi, a me ka hale kūʻai lāʻau āu e hoʻohana ai.
Kōkua kālā
Inā makemake ʻoe i kākoʻo kālā e uku no Ajovy, loaʻa ke kōkua.
ʻO Teva Pharmaceuticals, ka mea hana a Ajovy, he makana mālama kālā e hiki ke kōkua iā ʻoe e uku liʻiliʻi no Ajovy. No ka ʻike hou aku a ʻike inā ua kūpono ʻoe, e kipa i ka pūnaewele pūnaewele.
ʻIkea Ajovy
Hōʻike ka ʻikepili aʻe i nā hana maʻamau no Ajovy. Eia nō naʻe, e mālama pono i nā lāʻau a ke kauka i kuhikuhi ai nāu. E hoʻoholo kāu kauka i ka papa hana ʻoi loa nāu.
Nā ʻano lāʻau a me nā ikaika
Hele mai ʻo Ajovy i kahi syringe prefilled i hoʻokahi lāʻau. Loaʻa i kēlā me kēia syringe 225 mg o fremanezumab i 1.5 mL o ka hopena.
Hāʻawi ʻia ʻo Ajovy ma ke ʻano he injection i lalo o kou ʻili (subcutaneous). Hiki iā ʻoe ke hoʻomoe iho iā ʻoe iho i ka lāʻau i ka home, a i ʻole kahi mea mālama ola ke hāʻawi iā ʻoe i ka lāʻau i ke keʻena o kāu kauka.
Nā hana no ka pale ʻana i ka maʻi migraine
ʻElua mau papa hana lāʻau i koi ʻia:
- hoʻokahi 225-mg subcutaneous injection i hāʻawi ʻia i kēlā me kēia mahina, a i ʻole
- ʻekolu mau inikona subcutaneile 225-mg i hāʻawi ʻia (hoʻokahi a ma hope o kekahi) hoʻokahi manawa i kēlā me kēia ʻekolu mahina
E hoʻoholo ʻoe a me kāu kauka i ka papa hana dosing maikaʻi loa nāu, ma muli o kāu mau makemake a me kou nohona.
He aha inā e haʻo wau i kahi lāʻau?
Inā hoʻopoina a hala ʻole paha ʻoe i kahi lāʻau, lawelawe i ka lāʻau ma hope ke hoʻomanaʻo ʻoe.Ma hope o kēlā, e hoʻomau hou i ka papa kuhikuhi maʻamau i paipai ʻia.
ʻO kahi laʻana, inā ʻoe ma kahi papa manawa o ka mahina, e hoʻolālā i ka lāʻau aʻe no ʻehā mau pule ma hope o kāu mahele lāʻau. Inā ʻoe ma ka papahelu o ka hapahā, lawelawe i ka mahele lāʻau aʻe ma hope o 12 mau pule ma hope o kāu lāʻau make.
Pono wau e hoʻohana i kēia lāʻau lōʻihi?
Inā ʻoe a me kāu kauka e hoʻoholo i ka palekana a me ka maikaʻi o Ajovy iā ʻoe, hiki iā ʻoe ke hoʻohana i ka lāʻau lōʻihi lōʻihi e pale aku ai i ka ʻeha o ka migraine.
Pehea e lawe ai iā Ajovy
ʻO Ajovy kahi injection i hāʻawi ʻia ma lalo o ka ʻili (subcutaneous) hoʻokahi manawa i ka mahina a i hoʻokahi manawa i kēlā me kēia ʻekolu mahina. Hiki iā ʻoe ke lawelawe i ke kīkī iā ʻoe iho ma ka home, a i ʻole e hāʻawi kahi kahu mālama iā ʻoe i nā injection i ke keʻena o kāu kauka. ʻO ka manawa mua e loaʻa ai kahi kuhikuhi no Ajovy, hiki i kāu kauka olakino ke wehewehe pehea e hoʻopili ai i ka lāʻau iā ʻoe iho.
Hele mai ʻo Ajovy ma ke ʻano hoʻokahi, 225-mg prefilled syringe. Hoʻokahi wale nō mahele lāʻau kēlā me kēia syringe a makemake ʻia e hoʻohana hoʻokahi a laila hoʻolei ʻia.
Ma lalo iho nei ka ʻike e pili ana i ka hoʻohana ʻana i ka syringe i hana mua ʻia. No nā ʻike ʻē aʻe, wikiō, a me nā kiʻi o nā kuhikuhi hoʻoheheʻe, e ʻike i ka pūnaewele o ka mea hana.
Pehea e hoʻopili ai
Kau kauka kāu 225 mg i hoʻokahi manawa i kēlā me kēia mahina, a i ʻole 675 mg hoʻokahi manawa i kēlā me kēia ʻekolu mahina (hapahā). Inā kuhikuhi ʻia ʻoe i 225 mg i kēlā me kēia mahina, e hāʻawi ʻoe iā ʻoe iho i hoʻokahi injection. Inā kuhikuhi ʻia ʻoe i 675 mg i kēlā me kēia hapahā makahiki, hāʻawi ʻoe iā ʻoe iho i ʻekolu injection ʻokoʻa i kēlā me kēia.
Ke hoʻomākaukau nei e hoʻokomo
- He kanakolu mau minuke ma mua o ka hoʻokomo ʻana i ka lāʻau, hemo i ka syringe mai ka pahu hau. ʻAe kēia i ka lāʻau e hoʻomehana a hele mai i ka mahana wela. E mālama i ka pāpale ma ka syringe a hiki i kou mākaukau e hoʻohana i ka syringe. (Hiki ke mālama ʻia ʻo Ajovy i ka mahana o ka lumi a hiki i nā hola he 24. Inā mālama ʻia ʻo Ajovy ma waho o ka pahu hau no 24 mau hola me ka hoʻohana ʻole ʻia, mai hoʻihoʻi i loko o ka pahu hau. E hoʻolei iā ia i kāu pahu sharps.)
- Mai hoʻāʻo e hoʻomehana i ka syringe me ka wikiwiki e ka microwaving iā ia a i ʻole ka holo ʻana o ka wai wela ma luna ona. Eia kekahi, mai hoʻoluliluli ke ʻume. ʻO ka hana ʻana i kēia mau mea hiki ke hōʻemi iā Ajovy me ka maikaʻi ʻole.
- Ke lawe ʻoe i ke syringe mai loko mai o kāna ʻōpala, e pale pono iā ia mai ka mālamalama.
- ʻOiai ʻoe e kali ana i ka syringe e mahana ai i ka mahana o ka lumi, e kiʻi i ka gauze a i ʻole kahi popo pulupulu, kahi holoi waiʻona, a me kāu ipu hoʻolei sharps. Eia kekahi, e ʻike pono i ka helu pololei o nā syringes no kāu kauā i kuhikuhi ʻia.
- E nānā i ka syringe e hōʻoia ʻole ai ke ao a ua pau paha ka lāʻau. E hoʻomaʻemaʻe ka wai i melemele iki. Hiki inā loaʻa nā huʻa. Akā inā he discolored a cloudy paha ka wai, a inā he mau ʻāpana paʻa liʻiliʻi i loko ona, mai hoʻohana. A inā he mau māwae a kulu paha i ka syringe, mai hoʻohana ia mea. Inā pono, e kāhea i kāu kauka e pili ana i ka loaʻa ʻana o kahi hou.
- E hoʻohana i ke kopa a me ka wai e holoi i kou mau lima, a laila koho i ke kiko no kāu pahu kui. Hiki iā ʻoe ke hoʻopili i lalo o kou ʻili i kēia mau ʻekolu:
- ʻo ka mua o kou mau ʻūhā (ma ka liʻiliʻi he ʻelua ʻīniha ma luna o kou kuli a i ʻole ʻelua ʻīniha ma lalo o kou ʻūlū)
- ke kua o kou mau lima luna
- kou ʻōpū (ma ka liʻiliʻi ʻelua iniha ka mamao mai kāu pihi ʻōpū)
- Inā makemake ʻoe e hoʻokomo i ka lāʻau i loko o ka hope o kou lima, pono paha i kekahi e hoʻopili i ka lāʻau iā ʻoe.
- E hoʻohana i ka holoi ʻalekohola e hoʻomaʻemaʻe i ke kiko o ke komo āu i koho ai. E nānā pono e maloʻo loa ka ʻalekiko ma mua o kou hoʻōki ʻana i ka lāʻau.
- Inā ʻoe e hāʻawi iā ʻoe iho i ʻekolu mau kuʻina, mai hāʻawi iā ʻoe i kekahi o nā injection i ka wahi like. ʻAʻole loa e hoʻokomo i nā wahi i ʻulupā, ʻulaʻula, ʻulaʻula, kāka ʻia, a paʻakikī paha i ka hoʻopā.
Hoʻokomo i ka syringe prefilled Ajovy
- Lawe i ka pāpale kui kele o ka ʻekena a hoʻolei i ka ʻōpala.
- E ʻohi mālie i hoʻokahi ʻīniha o ka ʻili āu e makemake ai e hoʻopili.
- Hoʻokomo i ke kui kele i loko o ka ʻili i hoʻopaʻa ʻia ma ke kihi o 45 a 90 kekelē.
- I ka manawa e hoʻokomo piha ʻia ka nila, e hoʻohana i kou manamana nui e pahu mālie i ka plunger a hiki i ka wā e hele ai.
- Ma hope o ka hoʻopili ʻana iā Ajovy, huki pololei i ka nila mai ka ʻili a hoʻokuʻu i ka pā o ka ʻili. I mea e pale ʻole ai i ka hoʻopili ʻana iā ʻoe iho, mai hoʻopaʻa hou i ka nila.
- E kaomi mālie i ka pōpō pulupulu a i ʻole ka anana ma ka pūnaewele i hoʻokomo ʻia no kekahi mau kekona. Mai hamo i kahi.
- E hoʻolei i ke kiʻiona i hoʻohana ʻia a me ka nila i loko o kāu ipu hoʻolei sharps koke.
Manawa
E lawe ʻia ʻo Ajovy i hoʻokahi manawa i kēlā me kēia mahina a i hoʻokahi manawa i kēlā me kēia ʻekolu mau malama (hapahā), ke kaukaʻi ʻia i ka mea a kāu kauka i kauoha ai. Hiki ke lawe ʻia i kēlā me kēia manawa o ka lā.
Inā haʻalele ʻoe i kahi lāʻau, lawe koke iā Ajovy ke hoʻomanaʻo ʻoe. ʻO ka mahele aʻe e lilo i hoʻokahi mahina a i ʻole ʻekolu mau mahina ma hope o kou lawe i kēlā, ke kaukaʻi ʻia i kāu papa kuhikuhi dosing i koi ʻia. Hiki i kahi mea hoʻomanaʻo hoʻomanaʻo lāʻau ke kōkua iā ʻoe e hoʻomanaʻo e lawe iā Ajovy i ka papa kuhikuhi.
Lawe iā Ajovy me ka meaʻai
Hiki ke kiʻi ʻia ʻo Ajovy me ka ʻole o ka meaʻai.
Pehea e hana ai ʻo Ajovy
ʻO Ajovy kahi antibody monoclonal. ʻO kēia ʻano lāʻau lapaʻau kahi protein immune system kūikawā i hana ʻia i loko o kahi lab. Hana ʻo Ajovy ma ke kāpae ʻana i ka hana o kahi protein i kapa ʻia ʻo ka peptide e pili ana i ka ʻenekini kalona (CGRP). Pili ʻo CGRP i ka vasodilation (hoʻonui ʻia o nā kīʻaha koko) a me ka mumū i kou lolo.
Manaʻo ʻia ʻo CGRP he mea nui i ka hana ʻana i ka ulu o ka migraine. I ka ʻoiaʻiʻo, ke hoʻomaka ka poʻe i ka loaʻa i ka maʻi migraine, he kiʻekiʻe ko lākou o ka CGRP i ko lākou kahe koko. Kōkua ʻo Ajovy i ka mālama ʻana i ka maʻi migraine mai ka hoʻomaka ʻana me ke kāpae ʻana i ka hana o CGRP.
ʻO ka hapa nui o nā lāʻau e māka (hana) i nā kemika he nui a i ʻole nā ʻāpana o nā hunaola i kou kino. Akā ʻo Ajovy a me nā mea pale monoclonal ʻē aʻe e kau wale i hoʻokahi mea i ke kino. A ʻo kahi hopena, he mea liʻiliʻi paha ka launa ʻana o nā lāʻau a me nā hopena ʻē aʻe me Ajovy. E koho maikaʻi paha kēia no nā poʻe hiki ʻole ke lawe i nā lāʻau ʻē aʻe ma muli o nā hopena a i ʻole nā launa ʻana o ka lāʻau.
He koho maikaʻi paha ʻo Ajovy no ka poʻe i hoʻāʻo i nā lāʻau ʻē aʻe, akā ʻaʻole i lawa ka maikaʻi o nā lāʻau e hōʻemi ai i kā lākou helu o nā lā migraine.
Pehea ka lōʻihi o ka hana?
E hala paha i mau pule no ka loli ʻana o ka migraine a Ajovy i mea ai e ʻike ʻia. A he mau mahina paha e holo pono ai ka Ajovy.
Ua hōʻike ʻia nā hopena o nā noiʻi hoʻokolohua he nui ka poʻe i lawe iā Ajovy e ʻike i nā lā nui o ka migraine i loko o hoʻokahi mahina o ka lawe ʻana i kā lākou lāʻau mua. Ma kahi o kekahi mau mahina, ua hoʻomau ka emi o ka nui o nā lā o ka migraine no ka poʻe i ke aʻo ʻana.
Ajovy a me ka ʻalekohola
ʻAʻohe pilina ma waena o Ajovy a me ka waiʻona.
Eia nō naʻe, no kekahi poʻe, ʻo ka inu ʻana i ka waiʻona i ka wā e lawe nei iā Ajovy e like paha me ka mea e hōʻemi ai ka lāʻau. ʻO kēia no ka mea ʻo ka waiʻona ka mea e ulu ai ka migraine no nā poʻe he nui, a ʻo nā wai ʻona liʻiliʻi paha e hiki ai ke hōʻeha i ka migraine no lākou.
Inā ʻike ʻoe i ka ʻona ke kumu o ka ʻeha a ʻoi pinepine paha o ka ulu o ka migraine, pono ʻoe e hōʻalo i nā mea inu i loaʻa ka ʻalekohola.
Nā launa pū ʻo Ajovy
ʻAʻole i hōʻike ʻia ʻo Ajovy e launa pū me nā lāʻau ʻē aʻe. Eia nō naʻe, he mea nui e kamaʻilio pū me kāu kauka a kauka paha e pili ana i nā lāʻau i kuhikuhi ʻia, nā wikamina, nā mea hoʻohui, a me nā lāʻau lapaʻau over-the-counter āu e lawe ai ma mua o ka hoʻomaka ʻana iā Ajovy.
ʻO Ajovy a me ka hāpai keiki
ʻAʻole ʻike ʻia inā palekana ʻo Ajovy e hoʻohana i ka wā hāpai. I ka manawa i hāʻawi ʻia ai ʻo Ajovy i nā wahine hāpai i ka noiʻi holoholona, ʻaʻohe pilikia i hōʻike ʻia i ka hāpai keiki. Akā ʻaʻole nā wanana o nā noiʻi holoholona e wānana pinepine i ka hopena o ka lāʻau i nā kānaka.
Inā hāpai ʻoe a noʻonoʻo paha e pili ana i ka hāpai ʻana, e kamaʻilio me kāu kauka. Hiki iā lākou ke kōkua i ka hoʻoholo inā he koho maikaʻi ʻo Ajovy nāu. Pono ʻoe e kali e hoʻohana iā Ajovy a hiki i kou hāpai hou ʻole ʻana.
Ajovy a me ka waiū hānai
ʻAʻole maopopo inā hele ʻo Ajovy i ka waiū umauma kanaka. No laila, maopopo ʻole inā palekana ʻo Ajovy e hoʻohana i ka wā hānai.
Inā ʻoe e noʻonoʻo e pili ana i ka mālama ʻana iā Ajovy ʻoiai ʻoe e hānai ana i ka waiū, e kamaʻilio me kāu kauka e pili ana i nā pono a me nā pilikia i hiki ke hiki. Inā hoʻomaka ʻoe e lawe iā Ajovy, pono paha ʻoe e hōʻoki i ka hānai ʻana.
ʻO nā nīnau maʻamau e pili ana iā Ajovy
Eia nā pane i kekahi o nā nīnau e nīnau pinepine ʻia e pili ana iā Ajovy.
Hiki iā Ajovy ke hoʻohana e mālama i ka maʻi migraine?
ʻAʻole, ʻaʻole he lāʻau ʻo Ajovy no ka maʻi migraine. Kōkua ʻo Ajovy i ka pale ʻana i ka maʻi migraine ma mua o ka hoʻomaka ʻana.
Pehea ʻokoʻa ʻo Ajovy mai nā lāʻau migraine ʻē aʻe?
ʻOkoʻa ʻo Ajovy mai ka hapanui o nā lāʻau migraine ʻē aʻe no ka mea ʻo ia kekahi o nā lāʻau mua i hana ʻia e kōkua i ka pale ʻana i ka ʻeha o ka migraine. ʻO Ajovy kahi ʻāpana o kahi papa hou o nā lāʻau i kapa ʻia he antagonists peptide (CGRP) e pili ana i ka ʻaoʻao.
ʻO ka hapa nui o nā lāʻau ʻē aʻe i hoʻohana ʻia e pale aku ai i ka ʻeha o ka migraine i hoʻomohala ʻia no nā kumu like ʻole, e like me ka mālama ʻana i ka hopu ʻana, kaumaha, a i ʻole ke koko kiʻekiʻe. Hoʻohana ʻia ka hapa nui o kēia mau lāʻau i ka lepili e kōkua ai i ka pale ʻana i ka maʻi migraine.
ʻOkoʻa hoʻi ʻo Ajovy mai ka hapanui o nā lāʻau migraine ʻē aʻe i loko o ka injected i hoʻokahi manawa i ka mahina a i ʻole hoʻokahi manawa i kēlā me kēia ʻekolu mahina. ʻO ka hapa nui o nā lāʻau ʻē aʻe i hoʻohana ʻia e pale aku i ka maʻi migraine me he mau papa lā e pono ai ʻoe e lawe i hoʻokahi manawa i kēlā me kēia lā.
Hoʻokahi lāʻau lapaʻau Botox. ʻO Botox kahi injection, akā loaʻa iā ʻoe hoʻokahi manawa i kēlā me kēia ʻekolu mau mahina i ke keʻena o kāu kauka. Hiki iā ʻoe ke hoʻopili iā Ajovy iā ʻoe iho ma ka home a i ʻole kahi mea mālama ola e hāʻawi iā ʻoe i ka injection i ke keʻena o kāu kauka.
Eia nō hoʻi, ʻo Ajovy kahi antibody monoclonal, kahi ʻano lāʻau i hana ʻia mai nā pūnaewele ʻōnaehana pale. ʻAʻole e wāwahi ke akepaʻa i kēia mau lāʻau, e like me ka nui o nā lāʻau ʻē aʻe i hoʻohana ʻia e pale aku ai i ka maʻi migraine. ʻO kēia ke kumu o ka loaʻa ʻana o Ajovy a me nā lāʻau monoclonal ʻē aʻe i nā launa lāʻau ma mua o nā lāʻau ʻē aʻe e kōkua ai i ka pale ʻana i ka ʻeha o ka migraine.
Hoʻola ʻo Ajovy i ka huhū o ka migrain?
ʻAʻole, ʻaʻole kōkua ʻo Ajovy i ka hoʻōla ʻana i ka ʻeha o ka migraine. I kēia manawa, ʻaʻohe lāʻau i loaʻa e hiki ke hoʻōla i ka maʻi migraine. Hiki i nā lāʻau migraine ke loaʻa ke kōkua i ka pale ʻana a mālama ʻana i ka ʻeha o ka migraine.
Inā lawe wau iā Ajovy, hiki iaʻu ke oki i ka lawe ʻana i kaʻu mau lāʻau pale ʻē aʻe?
Pili ia. ʻOkoʻa ka pane a kēlā me kēia kanaka iā Ajovy. Inā hoʻemi ka lāʻau i ka helu o kāu maʻi migraine i lalo i kahi nui hiki ke mālama ʻia, hiki nō paha iā ʻoe ke hoʻokū i ka hoʻohana ʻana i nā lāʻau pale ʻē aʻe. Akā ke hoʻomaka ʻoe e lawe iā Ajovy, e kauoha aku paha kāu kauka me nā lāʻau lapaʻau ʻē aʻe.
Ua ʻike ʻia kahi noiʻi lapaʻau e palekana a maikaʻi hoʻi ʻo Ajovy no ka hoʻohana ʻana me nā lāʻau pale ʻē aʻe. ʻO nā lāʻau ʻē aʻe i kauoha ʻia e kāu kauka me Ajovy me topiramate (Topamax), propranolol (Inderal), a me kekahi mau antidepressants. Hiki ke hoʻohana pū ʻia ʻo Ajovy me onabotulinumtoxinA (Botox).
Ma hope o kou hoʻāʻo ʻana iā Ajovy no ʻelua a ʻekolu paha mahina, e kamaʻilio pū paha kāu kauka me ʻoe e ʻike i ke ʻano o ka maikaʻi o ka lāʻau iā ʻoe. I kēlā manawa, hoʻoholo paha ʻolua e hōʻoki i ka lawe ʻana i nā lāʻau pale ʻē aʻe, a i ʻole e hōʻemi i kāu mea hana no kēlā mau lāʻau.
ʻO overdose Ajovy
ʻO ke kuhi ʻana i nā kolamu he nui o Ajovy hiki ke hoʻonui i kou makaʻu i nā hopena o ka pūnaewele injection. Inā kūleʻa a hypersensitive paha ʻoe iā Ajovy, hopohopo paha ʻoe no kahi hopena koʻikoʻi hou aʻe.
Nā hōʻailona overdose
Hiki i nā ʻōuli o ka overdose ke komo pū me:
- ʻeha ʻeha, ʻili, a ʻulaʻula paha i kahi e kokoke ana i ka injection
- ʻōpala
- hives
- angioedema (ʻōhū ma lalo o ka ʻili)
- pehu o ka elelo, ka puʻu, a waha paha
- pilikia hanu
He aha e hana ai inā he overdose
Inā manaʻo ʻoe ua lawe nui ʻoe i kēia lāʻau, e kāhea i kāu kauka a i ʻole e ʻimi i ke alakaʻi mai ka ʻAmelika Hui Pū ʻIa Poison Control ma 800-222-1222 a i ʻole ma o kā lākou mea pono pūnaewele. Akā inā koʻikoʻi kāu mau ʻōuli, e kāhea iā 911 a i ʻole e hele koke i kahi lumi pilikia kokoke.
Nā ʻōlelo aʻoaʻo a Ajovy
Ma mua o ka lawe ʻana iā Ajovy, e kamaʻilio me kāu kauka e pili ana i kāu mōʻaukala olakino. ʻAʻole pono ʻoe e lawe iā Ajovy inā loaʻa iā ʻoe kahi moʻolelo o nā hopena hypersensitivity koʻikoʻi iā Ajovy a i ʻole kekahi o kāna mau mea hana. Hiki i kahi hopena hypersensitivity koʻikoʻi ke kumu i nā ʻōuli e like me:
- ʻāwīwī o ka ʻili
- ʻumeʻume
- pilikia hanu
- angioedema (ʻōhū ma lalo o ka ʻili)
- pehu o ke alelo, waha, a me ka puʻu
Pau ʻo Ajovy
Ke haʻalele ʻia ʻo Ajovy mai ka hale kūʻai lāʻau, e hoʻohui ka kauka i kahi lā palena pau i ka lepili ma ka ipu. ʻO kēia lā maʻamau hoʻokahi makahiki mai ka lā i hāʻawi ʻia ai ka lāʻau.
ʻO ke kumu o kēlā mau lā palena pau e hōʻoia i ka hopena o nā lāʻau i kēia manawa. ʻO ke kūlana o ka Food and Drug Administration (FDA) i kēia manawa e hōʻalo i ka hoʻohana ʻana i nā lāʻau i make.
Pehea ka lōʻihi o ka maikaʻi o ka lāʻau e hiki ai ke hilinaʻi i nā kumu he nui, me ke ʻano a me kahi e mālama ʻia ai ka lāʻau.
Pono e mālama ʻia nā syringes Ajovy i loko o ka pahu hau i ka pahu kumu e pale aku ai iā lākou mai ka mālamalama. Hiki iā lākou ke mālama palekana i ka pahu hau a hiki i 24 mau mahina, a i ʻole a hiki i ka lā palena pau i helu ʻia ma ka ipu. Ke lawe ʻia i waho o ka pahu hau, pono e hoʻohana i kēlā me kēia syringe i loko o 24 mau hola.
Inā loaʻa iā ʻoe kahi lāʻau i hoʻohana ʻole ʻia i hala i ka lā palena pau, e kamaʻilio me kāu kauka lāʻau e pili ana inā hiki paha iā ʻoe ke hoʻohana.
Hoʻolaha:Nūhou Lapaʻau i kēia lā ua hana i nā hana āpau e hōʻoia i ka pololei o nā ʻike āpau, laulā, a me kēia manawa. Eia nō naʻe, ʻaʻole pono e hoʻohana i kēia ʻatikala i pani no ka ʻike a me ka mākaukau o kahi loea mālama ola laikini. E nīnau mau ʻoe i kāu kauka a i ʻole ʻoihana olakino ʻē aʻe ma mua o ka lawe ʻana i nā lāʻau. Hiki ke loli i ka ʻike o ka lāʻau i loko a ʻaʻole i manaʻo ʻia e uhi i nā hoʻohana a pau, nā kuhikuhi, ka mālama ʻana, nā ʻōlelo aʻoaʻo, nā launa lāʻau, nā hopena maʻi ʻaʻai, a me nā hopena maikaʻi ʻole. ʻO ka loaʻa ʻole o nā ʻōlelo aʻoaʻo a i ʻole nā ʻike ʻē aʻe no kahi lāʻau i hāʻawi ʻia ʻaʻole ia e hōʻike i ka palekana o ka lāʻau a lāʻau paha i kūpono no nā mea maʻi āpau a i ʻole nā hoʻohana kikoʻī āpau.