Aldesleukin

Anter

• Ma mua o ka loaʻa ʻana o aldesleukin,
• Hoʻokumu ʻo Aldesleukin i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻ sectionlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka:
• Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

Pono e hāʻawi ʻia i ka pahu Aldesleukin i ka haukapila a i ʻole kahi wahi olakino ma lalo o ka nānā ʻana a ke kauka i ʻike i ka hāʻawi ʻana i nā lāʻau chemotherapy no ka maʻi ʻaʻai.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua ma mua a i kou wā o ka mālama ʻana e ʻike inā palekana iā ʻoe e loaʻa iā aldesleukin injection a e nānā i ka pane o kou kino i ka aldesleukin injection.

Hoʻokumu paha ʻo Aldesleukin i kahi hopena koʻikoʻi a hoʻoweliweli hoʻi i kapa ʻia ʻo capillary leak syndrome (kahi ʻano e mālama ai ke kino i ka nui o ka wai, ke kahe o ke koko, a me nā haʻahaʻa haʻahaʻa o kahi protein [albumin] i loko o ke koko) e hopena ai i kāu ka puʻuwai, nā māmā, nā puʻupaʻa, a me nā ʻōpū o ka gastrointestinal. Kū koke ka capillary leak syndrome ma hope koke o ka hāʻawi ʻia ʻana o aldesleukin. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e haʻi koke aku i kāu kauka: ka pehu ʻana o nā lima, nā wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo; loaʻa ke kaupaona; pokole o ka hanu; maule ana; ʻūpī a uila ʻole paha; huikau; koko a ʻeleʻele paha, hoʻolōʻihi, noho humuhumu; ʻeha ka umauma; wikiwiki a i ʻole kuʻi puʻuwai puʻuwai.

Hiki paha iā Aldesleukin ke hoʻemi i ka helu o nā hunaola keokeo i ke koko. ʻO ka hoʻemi ʻana i ka helu o nā hunaola keʻokeʻo i loko o kou kino e hoʻonui i ka makaʻu e hoʻomohala ʻoe i kahi maʻi koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e haʻi koke aku i kāu kauka: ke kuni, ke anu, ka ʻāʻī, ka ʻū, ka urination pinepine a ʻeha paha, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi.

Hiki i ka Aldesleukin ke hoʻololi i ka ʻōnaehana makaʻu a hiki ke hana i ka koma. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e haʻi koke aku i kāu kauka: ka hiamoe nui a luhi paha.

Hoʻohana ʻia ʻo Aldesleukin e mālama i ka carcinoma kōkō ʻoi loa (RCC, kahi ʻano maʻi ʻaʻai e hoʻomaka i ka puʻupaʻa) i pāhola ʻia i nā ʻāpana ʻē aʻe o kou kino. Hoʻohana ʻia ʻo Aldesleukin e mālama i ka melanoma (kahi ʻano o ka maʻi ʻaʻai ʻili) i hoʻolaha ʻia i nā ʻāpana ʻē aʻe o kou kino. Aia ʻo Aldesleukin i kahi papa o nā lāʻau i ʻike ʻia he cytokines. ʻO ia kahi mana i hana ʻia e ke kanaka o kahi protein i kūlohelohe e hoʻonāukiuki i ke kino e hana i nā kemika ʻē aʻe e hoʻonui i ka hiki i ke kino ke hakakā i ka maʻi ʻaʻai.

Hele mai ʻo Aldesleukin ma ke ʻano he pauka e kāwili ʻia me ka wai e hoʻokomo ʻia i loko o ke aniani (i kahi aa) ma mua o 15 mau minuke e ke kauka a kahu hānai paha i kahi haukapila. Hoʻokomo pinepine ʻia ia i kēlā me kēia 8 mau hola no 5 mau lā i ka lālani (ʻo ka huina o 14 nā injection). Hiki ke hana hou i kēia pōʻaiapuni ma hope o 9 mau lā. Pili ka lōʻihi o ka mālama ʻana i ka maikaʻi o ka pane ʻana o kou kino i ka lāʻau.

Pono paha kāu kauka e hoʻolohi a hoʻopau paha i kāu lāʻau lapaʻau inā ʻike ʻoe i kekahi mau hopena ʻaoʻao. E nānā pono ʻoe i kāu mālama ʻana me aldesleukin. He mea nui iā ʻoe e haʻi i kāu kauka i kou ʻano i kou wā e mālama ai me aldesleukin.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka loaʻa ʻana o aldesleukin,

• e haʻi aku i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka aldesleukin, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i ka aldesleukin injection. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E kuhikuhi pono i kekahi o kēia mau mea: beta blockers e like me atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), a me propranolol (Inderal); kekahi mau lāʻau chemotherapy chemotherapy e like me asparaginase (Elspar), cisplatin (Platinol), dacarbazine (DTIC-dome), doxorubicin (Doxil), interferon-alfa (Pegasys, PEG-Intron), methotrexate (Rheumatrex, Trexall), a me tamoxifen (Nolvx) ); nā lāʻau no ke koko kiʻekiʻe; nā lāʻau no ka nausea a me ka luaʻi; narcotics a me nā lāʻau ʻeha ʻē aʻe; nā mea hoʻonanea, nā lāʻau moe, a me nā tranquilizers; nā steroid e like me dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), a me prednisone (Deltasone); a me nā kalima steroid, nā lotion, a me nā hamo e like me hydrocortisone (Cortizone, Westcort). E haʻi aku i kāu kauka a me ka mea kauka lāʻau e pili ana i nā lāʻau a pau āu e lawe nei i hiki iā lākou ke nānā inā paha e hoʻonui paha kekahi o kāu mau lāʻau i ka makaʻu e hoʻomohala ʻoe i ka hakuʻala a me ka hōʻeha o ke ake i kāu mālama ʻana me aldesleukin.
• e haʻi i kāu kauka inā loaʻa mua ʻoe i ka hopu ʻana, gastrointestinal (GI) e koi ana i ka lāʻau ʻokiʻoki, a i ʻole nā ​​GI koʻikoʻi, ka puʻuwai, nā ʻōnaehana, a me nā pilikia puʻuwai ma hope o kou loaʻa ʻana iā aldesleukin a i ʻole inā loaʻa iā ʻoe kahi lāʻau hoʻoliʻiliʻi (ʻoki e hoʻololi i kahi ʻōhua i ke kino). ʻAʻole paha makemake kāu kauka iā ʻoe e loaʻa iā aldesleukin.
• e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa paha i nā maʻi o ka maʻi, Crohn's disease, scleroderma (kahi maʻi e hoʻopili i nā kino i kākoʻo i ka ʻili a me nā mea o loko), maʻi thyroid, arthritis, diabetes, myasthenia gravis (kahi maʻi e hoʻonāwaliwali i nāʻiʻo), a i ʻole cholecystitis (ka huhū o ke au o ke au e ʻeha nui ai).
• e haʻi i kāu kauka inā hāpai ʻoe, hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka loaʻa ʻana iā aldesleukin, e kāhea i kāu kauka. ʻAʻole pono ʻoe e hānai i ka umauma ʻoiai ke loaʻa nei iā aldesleukin.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

Hoʻokumu ʻo Aldesleukin i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• nausea
• ka luaʻi
• pāhoehoe
• nalo ʻai ʻole
• ʻeha ma ka waha a me ka puʻu
• luhi
• nāwaliwali
• ʻūpā
• manaʻo laulā o ka maikaʻi ʻole
• ʻeha a ʻulaʻula paha ma kahi i hāʻawi ʻia ai ka pahu kui

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻ sectionlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka:

• ka hopu ʻana
• ʻeha ka umauma
• hopohopo loa
• pīhoihoi a pīhoihoi paha
• kaumaha hou a i ʻole ke kaumaha paha
• ke ʻike nei i nā mea a i ʻole ka lohe ʻana i nā leo i ʻole (hallucinating)
• nā hoʻololi i kāu hihiʻo a kamaʻilio paha
• nalo o ke kūlike
• hoʻēmi i ka makaʻala
• ʻāpā ʻaʻano ʻole a hoʻokahe koko paha
• hiamoe nui a luhi paha
• paʻakikī i ka hanu ʻana
• ʻūhā
• ʻeha ka ʻōpū
• melemele o ka ʻili a me nā maka
• hoʻemi urination
• hūwī
• hives
• ʻūlili
• pilikia i ka hanu ʻana a i ʻole ke ale ʻana

Hoʻokumu paha ʻo Aldesleukin i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

• ka hopu ʻana
• wikiwiki a i ʻole kuʻi puʻuwai puʻuwai
• koma
• hoʻemi urination
• ka pehu o ka maka, nā lima, nā lima, nā wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
• luhi ʻole a nawaliwali paha
• ʻeha ka ʻōpū
• luaʻi ka mea koko a nānā paha e like me nā kahua kope
• ke koko i ka noho
• pahu noho ʻeleʻele a lohi hoʻi

Inā loaʻa iā ʻoe nā kukuna x, e haʻi i ke kauka ke loaʻa nei iā ʻoe ka aldesleukin therapy.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Proleukin^®

• Interleukin-2