Virilization

ʻO ka Virilization kahi kūlana kahi e hoʻomohala ai ka wahine i nā ʻano e pili ana i nā kāne kāne (androgens), a i ʻole ke loaʻa i kahi keiki hānau hou nā hiʻohiʻona o ka hanana kāne kāne i ka wā hānau.

Hoʻokumu ʻia paha ka Virilization e:

• ʻO ka hana testosterone nui loa
• Hoʻohana o nā anabolic steroid (hana-hoʻonui ʻana a i ʻole pili i ka hoʻokau hou ʻia o ke kāne)

I nā keikikāne a kaikamahine paha, hānau ʻia ke kumu e:

• ʻO kekahi mau lāʻau i lawe ʻia e ka makuahine i ka wā hāpai
• ʻO ka hyperplasia adrenal congenital i ka pēpē a i ʻole ka makuahine
• ʻO nā kūlana olakino ʻē aʻe i ka makuahine (e like me nā tumors o nā ovaries a i ʻole nā ​​adrenal gland e hoʻokuʻu i nā homone kāne)

I nā kaikamahine e hele nei i ka wā ʻōpio, ʻo ke kumu ke kumu.

• ʻO Polycystic ovary syndrome
• ʻO kekahi mau lāʻau, a i ʻole nā ​​anabolic steroid
• ʻO hyperplasia adrenal congenital
• Nā tumors o nā ovaries, a i ʻole nā ​​adrenal glands e hoʻokuʻu i nā homone kāne (androgens)

I nā wahine makua, kumu ʻia ke ʻano e:

• ʻO kekahi mau lāʻau, a i ʻole nā ​​anabolic steroid
• Nā tumors o nā ovaries a i ʻole nā ​​adrenal glands e hoʻokuʻu i nā kāne kāne

ʻO nā hōʻailona o ka virilization i ka wahine hilinaʻi pinepine i ka pae o ka testosterone i ke kino.

Papa haʻahaʻa (maʻa mau):

• Mānoanoa, lauoho lauoho ʻeleʻele i ka ʻumiʻumi a me kahi ʻumiʻumi
• Hoʻonui i ka lauoho o ke kino
• ʻO ka ʻili aila a huehue paha
• Nā wā menstrual maʻamau

Kūlana haʻahaʻa (ʻike ʻole):

• ʻŌhule ʻaʻano kāne
• ʻO ka nalowale ʻana o ka hoʻoili momona wahine
• Hoemi i ka nui o ka umauma

Papa kiʻekiʻe (kākaʻikahi):

• Ka hoʻonui ʻana o ka clitoris
• Hoʻoneʻe ʻana i ka leo
• Mānā mākala kāne

E komo pū paha nā hoʻāʻo:

• Nā hōʻoia koko e ʻike i ka nui o ka testosterone i nā wahine
• CT scan, MRI, a i ʻole ultrasound e kāpae i nā tumors o nā ovaries a me nā adrenal adrenal

Inā hopena ʻia ka virilization e ka hōʻike ʻana i nā androgens (nā kāne kāne kāne) i nā mākua wahine, hele aku ka hapa nui o nā ʻōuli ke pau nā kūmole. Eia nō naʻe, ʻo ka hohonu ʻana o ka leo kahi hopena mau o ka hōʻike ʻana i nā androgens.

• ʻO ka hana Hypothalamus hormone

ʻO Gooren LJ. ʻO ka endocrinology o ka moekolohe a me ka ʻike kāne. I: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Makua a Pediatric. ʻEpekema 7 Piladelapia, PA: Elsevier Saunders; 2016: chap 124.

ʻO Styne DM, Grumbach MM. Physiology a me nā maʻi o ka wā ʻōpio. I: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. ʻO Williams Textbook of Endocrinology. 13th ed. Piladelapia, PA: Elsevier; 2016: chap 25.