ʻO Thioguanine
Anter
- Ma mua o ka lawe ʻana i thioguanine,
- Hiki i Thioguanine ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
- Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:
- Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:
Hoʻohana ʻia ʻo Thioguanine e mālama i ka leukemia myeloid koʻikoʻi (AML; kahi ʻano maʻi ʻaʻai e hoʻomaka i nā hunaola keokeo).Aia ʻo Thioguanine i kahi papa o nā lāʻau i ʻike ʻia me nā analogine purine. Hana ia ma ka hoʻolohi a hoʻopaʻa ʻana i ka ulu ʻana o nā hunaola maʻi ʻaʻai i loko o kou kino.
Hele mai ʻo Thioguanine ma ke ʻano he papa e lawe ma ka waha i hoʻokahi manawa i ka lā. Aia ka lōʻihi o ka mālama ʻana i nā ʻano lāʻau āu e lawe nei, pehea ka maikaʻi o ka pane ʻana o kou kino iā lākou, a me ke ʻano o ka maʻi ʻaʻai āu. E lawe i ka thioguanine ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono i ka thioguanine e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.
Hiki i kāu kauka ke hoʻonui a hōʻemi paha i kāu lāʻau o thioguanine i kāu wā e lapaʻau ai. Aia kēia i ka maikaʻi o ka hana ʻana o ka lāʻau iā ʻoe a me nā hopena ʻaoʻao āu e ʻike ai. E kamaʻilio me kāu kauka e pili ana i kou ʻano i kāu mālama ʻana. E hoʻomau i ka lawe ʻana i thioguanine ʻoiai ʻoe e manaʻo maikaʻi. Mai hōʻoki i ka lawe ʻana i thioguanine me ke kamaʻilio ʻole ʻana me kāu kauka
E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.
Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.
Ma mua o ka lawe ʻana i thioguanine,
- e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka thioguanine, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa thioguanine. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
- e haʻi i kāu kauka inā ua lawe mua ʻoe i ka thioguanine a i ʻole ka merc laptopurine e mālama ai i kāu maʻi ʻaʻai. ʻ telllelo paha kāu kauka iā ʻoe ʻaʻole e lawe i ka thioguanine inā ʻaʻole i holo pono kekahi o kēia mau lāʻau i kū i kou maʻi ʻaʻai i ka wā i hala.
- e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: aminosalicylates e like me mesalamine (Apriso, Asacol, Pentasa, a me nā mea ʻē aʻe), olsalazine (Dipentum), a me sulfasalazine (Azulfidine). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. E haʻi aku i kāu kauka a me ka mea kauka lāʻau e pili ana i nā lāʻau a pau āu e lawe nei i hiki iā lākou ke nānā inā paha e hoʻonui paha kekahi o kāu mau lāʻau i ka makaʻala e hoʻomohala ʻoe i ka hōʻino o ke ake i kāu mālama ʻana me thioguanine
- e haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi ate.
- e haʻi i kāu kauka inā hāpai ʻoe, hoʻolālā e hāpai, a i ʻole e hānai umauma ana. ʻAʻole pono ʻoe e hāpai a i ʻole hānai umauma ke loaʻa ʻoe iā thioguanine. Inā hāpai ʻoe i ka loaʻa ʻana iā thioguanine, e kāhea i kāu kauka. Hiki paha i Thioguanine ke hōʻeha i ka fetus.
- ʻaʻohe o nā lāʻau āpau ke kamaʻilio ʻole ʻia me kāu kauka.
- pono ʻoe e ʻike ʻoi aku ka kiʻekiʻe o ka hopena āu e hoʻomohala ai i nā hopena ʻē aʻe o thioguanine inā loaʻa iā ʻoe kahi hopena pilikino (hoʻoilina). E kauoha paha kāu kauka i nā hoʻokolohua ma mua a i ʻole i kāu wā e mālama ai e ʻike inā loaʻa iā ʻoe kēia mea pilikia.
Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.
Inu nui o nā wai i kou wā e mālama ai me thioguanine.
E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.
Hiki i Thioguanine ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
- nausea
- ka luaʻi
- lilo o ka makemake a kaumaha paha
- ʻeha ma ka waha a me ka puʻu
- ʻeha poʻo
Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:
- luhi ʻole a nawaliwali paha
- kahe koko ʻole ʻana a palapū paha
- melemele o ka ʻili a me nā maka
- nā ʻōuli like flu
- pehu o ka ʻōpū wahi
- ʻeha o ka ʻōpū, ʻo ka ʻaoʻao ʻākau o ka ʻōpū
- pehu o ka maka, lima, lima, wāwae, kuʻekuʻe wāwae a i ʻole nā wāwae lalo
- luaʻi koko
- ʻūlū ʻeleʻele, lohi a koko paha
- fiva, ʻāʻī puʻupuʻu, ʻūhū mau a me ka paʻa, a i ʻole nā hōʻailona ʻē aʻe o ka maʻi
- pokole o ka hanu
- ʻālohilohi
Hiki i Thioguanine ke kumu i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.
Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).
E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.
Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.
He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org
I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.
Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:
- nausea
- ka luaʻi
- sweating nui loa
- luhi ʻole a nawaliwali paha
- kahe koko ʻole ʻana a palapū paha
- fiva, ʻāʻī puʻupuʻu, ʻūhū mau a me ka paʻa, a i ʻole nā hōʻailona ʻē aʻe o ka maʻi
E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha paha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino iā thioguanine.
Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.
He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.
- Tabloid®
- 2-Amino-6-merc laptopurine
- 6-TG
- 6-Thioguanine