Methotrexate

Anter

• Ma mua o ka lawe ʻana i ka methotrexate,
• Hiki i ka Methotrexate ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻ sectionlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka:

Hiki i ka Methotrexate ke kumu i nā hopena ʻino loa a weliweli hoʻi i ke ola. Lawe wale ʻoe i ka methotrexate e mālama i ka maʻi ʻaʻai a i ʻole kekahi mau ʻano ʻē aʻe i koʻikoʻi loa a ʻaʻole hiki ke mālama ʻia me nā lāʻau ʻē aʻe. E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka lawe ʻana i ka methotrexate no kāu maʻi.

E haʻi i kāu kauka inā loaʻa a loaʻa paha iā ʻoe ka nui o ka wai i kou wahi o kou ʻōpū a i ʻole ma kahi ākea e pili ana i kou mau māmā a inā loaʻa ʻoe a i ʻole loaʻa i ka maʻi puʻupaʻa. E haʻi pū aku i kāu kauka inā lawe ʻoe i nā lāʻau anti-inflammatory nonsteroidal (NSAIDs) e like me ka aspirin, choline magnesium trisalicylate (Tricosal, Trilisate), ibuprofen (Advil, Motrin), magnesium salicylate (Doan's), naproxen (Aleve, Naprosyn), a i ʻole salsalate. Hiki i kēia mau kūlana a me nā lāʻau ke hoʻonui i ka makaʻu e hoʻomohala ʻoe i nā hopena ʻē aʻe o ka methotrexate. E nānā pono kāu kauka iā ʻoe a pono paha e hāʻawi iā ʻoe i ka lāʻau ma lalo o ka methotrexate a i ʻole hoʻokū i kāu lāʻau me methotrexate.

Hiki i ka Methotrexate ke hoʻemi i ka helu o nā hunaola i hana ʻia e kou iwi iwi. E haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa i kahi helu haʻahaʻa o kekahi ʻano o nā hunaola koko a i ʻole nā ​​pilikia ʻē aʻe i kāu mau huna koko. Kāhea koke i kāu kauka inā ʻike ʻoe i kekahi o nā ʻōuli penei: ʻeha puʻu, ʻalalā, fiva, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi. ʻehaʻeha a hoʻokahe koko paha; luhi nui loa; ʻili mae; a me ka pōkole o ka hanu.

Hiki i ka Methotrexate ke hōʻeha i ka ate, keu hoʻi ke lawe ʻia no kahi wā lōʻihi. Inā inu ʻoe a inu paha i ka wai ʻona he nui a i ʻole inā loaʻa a loaʻa paha ʻoe i ka maʻi ate, hiki i kāu kauka ke ʻōlelo aku iā ʻoe ʻaʻole e lawe i ka methotrexate ke ʻole ʻoe he ʻano maʻi maʻi maʻi o ka maʻi ʻaʻai no ka mea ʻoi aku ka nui o ka makaʻu e loaʻa iā ʻoe. hoʻomōhala poino ate. ʻOi aku ka kiʻekiʻe o ka makaʻu āu e hoʻomohala ai i ka hōʻino o ke ake inā ʻelemakule ʻoe, paʻakikī, a maʻi diabetes paha. E haʻi i kāu kauka inā lawe ʻoe i kekahi o nā lāʻau aʻe: acitretin (Soriatane), azathioprine (Imuran), isotretinoin (Accutane), sulfasalazine (Azulfidine), a i ʻole tretinoin (Vesanoid). E noi i kāu kauka e pili ana i ka hoʻohana palekana o nā inu waiʻona ʻoiai ke lawe nei ʻoe i ka methotrexate. Kāhea koke i kāu kauka inā ʻike ʻoe i kekahi o nā ʻōuli penei: kahoʻi, luhi nui loa, nele i ka ikaika, nalowale o ka makemake, ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū, melemele o ka ʻili a me nā maka, a i ʻole nā ​​hōʻailona like flu. Hiki i kāu kauka ke kauoha aku i nā biopsies o ke ake (e hemo ana i kahi ʻāpana o ke akepaʻa ake e nānā ʻia i loko o kahi keʻena hoʻokolohua) ma mua a ma kāu mālama ʻana me methotrexate

Hiki i ka Methotrexate ke hōʻeha i ka māmā. E haʻi i kāu kauka inā loaʻa a loaʻa paha iā ʻoe i ka maʻi lolo. Kāhea koke i kāu kauka inā ʻike ʻoe i kekahi o nā ʻōuli penei: ka puʻu maloʻo, ke kuni, a me ka liʻiliʻi o ka hanu.

Hiki i ka Methotrexate ke hoʻopōʻino i ka uhi o kou waha, ʻōpū, a me kou ʻōpū. E haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa paha nā puʻupuʻu o ka ʻōpū a i ʻole colitis ulcerative (kahi ʻano e hoʻoulu ai a me nā ʻeha i ka uhi o ke kolona [ʻōpū nui] a me ka ʻūhā. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e hoʻōki i ka lawe ʻana i ka methotrexate a kāhea koke aku i kāu kauka: ʻeha o ka waha, diarrhea, ʻeleʻele, lohi, a i ʻole nā ​​noho koko, a i ʻole ka luaʻi e pili koko a ʻano like paha me nā kumu kope

Lawe i ka methotrexate e hoʻonui i ka makaʻu e hoʻomohala ʻoe i ka lymphoma (maʻi ʻaʻai e hoʻomaka i nā hunaola o ka ʻōnaehana paleʻea. Inā hoʻomohala ʻoe i ka lymphoma, hele aku paha ia me ka ʻole o ka lāʻau ke hoʻopau ʻoe i ka lawe ʻana i ka methotrexate, a i ʻole pono e mālama ʻia me chemotherapy.

Inā ʻoe e lawe i ka methotrexate e mālama i ka maʻi ʻaʻai, hiki iā ʻoe ke hoʻomohala i kekahi mau pilikia e like me ka hana ʻana o ka methotrexate e luku i nā hunaola maʻi ʻaʻai. E nānā pono kāu kauka iā ʻoe a mālama i kēia mau pilikia inā kū lākou.

Hiki i ka Methotrexate ke kumu i nā hopena ʻili koʻikoʻi a hoʻoweliweli paha i ke ola. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: ke kuni, ka pehu, ka pehu, a me ka ʻili ihi.

Hiki i ka Methotrexate ke hoʻemi i ka hana o kāu ʻōnaehana pale, a ke hoʻomohala paha ʻoe i nā maʻi koʻikoʻi. E haʻi i kāu kauka inā loaʻa iā ʻoe kekahi ʻano maʻi a inā loaʻa a loaʻa paha iā ʻoe kekahi ʻano e hoʻopili i kāu ʻōnaehana pale maʻi. E haʻi paha kāu kauka iā ʻoe ʻaʻole pono ʻoe e lawe i ka methotrexate ke ʻole ʻoe e loaʻa i ka maʻi ʻaʻai ola. Inā ʻike ʻoe i nā hōʻailona o ka maʻi e like me ka ʻāʻī ʻeha, ʻū, kuni, a me ke anuanu, e kelepona koke i kāu kauka.

Inā lawe ʻoe i ka methotrexate ʻoiai ke mālama ʻia ʻoe me ka radiation therapy no ka maʻi ʻaʻai, hoʻonui paha ka methotrexate i ka makaʻu o ka radiation radiation i mea e hōʻino ai i kou ʻili, iwi, a i ʻole nā ​​ʻāpana ʻē aʻe o kou kino.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab ma mua, i ka wā, a ma hope o kāu mālama ʻana e nānā i ka pane o kou kino i ka methotrexate a e mālama i nā hopena ma mua o ka lilo ʻana i mea koʻikoʻi.

E haʻi i kāu kauka inā hāpai ʻoe a i ʻole kāu pakanā paha e hoʻolālā e hāpai. Inā he wahine ʻoe, pono ʻoe e lawe i kahi hōʻike hāpai keiki ma mua o kou hoʻomaka ʻana i ka methotrexate. E hoʻohana i kahi ʻano pono o ka kaohi hānau ʻana i ʻole e hāpai a i ʻole kāu pakanā i ka wā a ma hope koke paha o kāu lāʻau. Inā he kāne ʻoe, pono ʻoe a me kāu wahine e hoʻohana i ka kaohi hānau no 3 mau mahina ma hope o kou hoʻōki ʻana i ka lawe ʻana i ka methotrexate. Inā he wahine ʻoe, pono ʻoe e hoʻomau i ka hoʻohana ʻana i ka kaohi hānau a hiki i kou loaʻa ʻana o hoʻokahi manawa menstrual i hoʻomaka ma hope o kou hōʻoki ʻana i ka lawe ʻana i ka methotrexate. Inā hāpai ʻoe a ʻo kāu hoa paha, e kāhea koke i kāu kauka. Hiki i ka Methotrexate ke hōʻeha a make paha i ka fetus.

Hoʻohana ʻia ka Methotrexate e mālama i ka psoriasis koʻikoʻi (kahi maʻi ʻili kahi e hana ai nā ʻulaʻula, scaly patch ma kekahi mau wahi o ke kino) i hiki ʻole ke kāohi ʻia e nā ʻano lāʻau ʻē aʻe. Hoʻohana pū ʻia ʻo Methotrexate me ke koena, ka hoʻōla kino, a i kekahi manawa i nā lāʻau ʻē aʻe e mālama ai i ka rheumatoid arthritis (RA; kahi ʻano e hoʻouka ai ke kino i kāna mau hui ponoʻī, e hōʻeha ai i ka ʻeha, ka pehu ʻana, a me ka nalo ʻana o ka hana) ʻaʻole hiki ke kaohi ʻia e kekahi mau lāʻau ʻē aʻe. Hoʻohana ʻia ʻo Methotrexate e mālama i kekahi ʻano maʻi ʻaʻai e like me nā maʻi ʻaʻai e hoʻomaka i nā aʻa e hana a puni i kahi hua manu i hoʻomohala ʻia i ka pūpū, ka maʻi ʻaʻai umauma, maʻi ʻaʻa pūhaʻa, kekahi mau maʻi maʻi o ke poʻo a me ka ʻāʻī, kekahi mau ʻano lymphoma, a me leukemia (maʻi ʻaʻai. e hoʻomaka i nā keokeo o ke koko). Aia ka Methotrexate i kahi papa o nā lāʻau i kapa ʻia antimetabolites. Mālama ʻo Methotrexate i ka maʻi ʻaʻai ma ka hoʻolōʻihi ʻana i ka ulu ʻana o nā hunaola maʻi ʻaʻai. Mālama ʻo Methotrexate i ka psoriasis ma ka hoʻolōʻihi ʻana i ka ulu ʻana o nā ʻili ʻili e hoʻōki i nā unahi mai ka hana ʻana. Hiki paha i ka Methotrexate ke mālama i ka rheumatoid arthritis ma o ka hōʻemi ʻana i ka hana o ka ʻōnaehana pale.

Hele mai ʻo Methotrexate ma ke ʻano he papa e lawe ma ka waha. E haʻi aku kāu kauka iā ʻoe i ka manawa pinepine e lawe ai i ka methotrexate. Aia ka papa kuhikuhi i ke kūlana āu i loaʻa ai a pehea e pane ai kou kino i ka lāʻau.

E haʻi paha kāu kauka iā ʻoe e lawe i ka methotrexate ma kahi papa huli e hoʻololi ai i kekahi mau lā ke lawe ʻoe i ka methotrexate me kekahi mau lā a i ʻole mau pule ke lawe ʻole ʻoe i ka lāʻau. E hāhai pono i kēia mau ʻōkuhi a nīnau i kāu kauka a kauka paha inā ʻaʻole ʻoe e ʻike i ka wā e lawe ai i kāu lāʻau.

Inā ʻoe e lawe nei i ka methotrexate e mālama i ka psoriasis a i ʻole ka rheumatoid arthritis, hiki i kāu kauka ke ʻōlelo iā ʻoe e lawe i ka lāʻau i hoʻokahi manawa i ka pule. E nānā pono i nā kuhikuhi a kāu kauka. ʻO kekahi poʻe i lawe kuhi hewa i ka methotrexate hoʻokahi i kēlā me kēia lā ma kahi o hoʻokahi pule i kēlā me kēia pule ʻike i nā hopena ʻino loa a i make paha.

E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe i ka methotrexate e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

Inā ʻoe e lawe i ka methotrexate e mālama i ka psoriasis a i ʻole ka rheumatoid arthritis, hiki i kāu kauka ke hoʻomaka iā ʻoe ma kahi haʻahaʻa o ka lāʻau a hoʻonui i kāu lāʻau. E hāhai pono i kēia mau ʻōkuhi.

Inā ʻoe e lawe i ka methotrexate e mālama i ka rheumatoid arthritis, e 3 a 6 mau pule paha ka manawa e hoʻomaka ai ka hoʻomaikaʻi ʻana o kāu mau ʻōuli, a he 12 mau pule a ʻoi aku paha ka lōʻihi iā ʻoe e ʻike i ka pono piha o ka methotrexate. E hoʻomau i ka lawe i ka methotrexate ʻoiai ʻoe e manaʻo maikaʻi. Mai hōʻoki i ka lawe ʻana i ka methotrexate me ke kamaʻilio ʻole ʻana me kāu kauka.

Hoʻohana ʻia ʻo Methotrexate i kekahi manawa e mālama i ka maʻi o Crohn (ke ʻano e hoʻouka ai ka ʻōnaehana pale i ka uhi o ka digestive tract, e hōʻeha ai i ka ʻeha, ka maʻi pākī, ka pohō kaumaha a me ke kuni), sclerosis he nui (MS; ke ʻano e hoʻouka ai ka ʻōnaehana pale i nā aʻa, ke kumu o ka nāwaliwali, numbness, nalo ʻana o ka hoʻohui ʻana o nā mākala, a me nā pilikia me ka hihi, ʻōlelo, a me ka mālama ʻana i ka maʻi ʻaʻa), a me nā maʻi autoimmune ʻē aʻe (nā kūlana e hoʻomohala i ka wā e hoʻouka hewa ka ʻōnaehana immune i nā hunaola olakino i loko o ke kino e kuhihewa). E noi i kāu kauka e pili ana i ka makaʻu o ka hoʻohana ʻana i kēia lāʻau no kou maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka methotrexate,

• e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka methotrexate, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa methotrexate. E noi i kāu kauka a kauka paha no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, nā mea hoʻopihaʻai, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe E ʻōlelo pono i nā lāʻau i helu ʻia i ka ʻARlelo AOAO IMPORTANT a me kekahi o nā mea penei: kekahi antibiotics e like me chloramphenicol (chloromycetin), penicillins, a me tetracyclines; waikawa folic (loaʻa wale a i ʻole me he mea hoʻohui i kekahi mau multivitamins); nā lāʻau ʻē aʻe no ka rheumatoid arthritis; phenytoin (Dilantin); probenecid (Benemid); sulfonamides e like me co-trimoxazole (Bactrim, Septra), sulfadiazine, sulfamethizole (Urobiotic), a me sulfisoxazole (Gantrisin); a me theophylline (Theochron, Theolair). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole kekahi o nā ʻano i ʻōlelo ʻia i loko o ka ʻARlelo Aʻoaʻo IMPORTANT a i ʻole ka pae folate haʻahaʻa i loko o kou koko.
• mai hānai umauma ʻoiai ʻoe e lawe ana i ka methotrexate.
• inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o nā niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe nei ʻoe i ka methotrexate.
• hoʻolālā e hōʻalo i ka pono ʻole a hoʻolōʻihi ʻia paha i ka lā o ka lā a i ʻole ke kukui ultraviolet (nā moena ʻili a me nā sunlamp) a e komo i nā lole pale, nā aniani aniani, a me nā pale pale lā. Hana paha ʻo Methotrexate i kou ʻili i ka lā a i ʻole ke kukui ultraviolet. Inā loaʻa iā ʻoe ka psoriasis, e ʻoi aku paha ka ʻeha o kou ʻeha inā hōʻike ʻoe i kou ʻili i ka lā ʻoiai ʻoe e lawe nei i ka methotrexate.
• ʻaʻohe o nā lāʻau lapaʻau i ka wā o kāu mālama ʻana me ka methotrexate me ke kamaʻilio ʻole ʻana me kāu kauka.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hiki i ka Methotrexate ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• ʻūpā
• hiamoe
• ʻeha poʻo
• ʻōhū, pulu
• hoʻēmi ʻai
• maka ʻulaʻula
• poho lauoho

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻ sectionlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka:

• ʻike hihi ʻole a i ʻole nalo ʻana o ka hihiʻo
• ka hopu ʻana
• huikau
• nāwaliwali a paʻakikī paha i ka neʻe ʻana i kekahi a i ʻole ʻelua ʻaoʻao o ke kino
• nalowale o ka ʻike

Hiki i ka Methotrexate ke kumu i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Rheumatrex^®
• Trexall^®

• Amethopterin
• MTX