ʻO Decitabine lāua ʻo Cedazuridine

Anter

• Ma mua o ka lawe ʻana i ka decitabine a me ka cedazuridine,
• Hiki i ka Decitabine a me ka cedazuridine ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hoʻohana ʻia ka hui pū ʻana o decitabine a me cedazuridine e mālama i kekahi ʻano o ka myelodysplastic syndrome (nā ʻano e hana ai ka iwi iwi i nā hunaola koko e misshapen a ʻaʻole lawa pono nā kaola koko olakino), e like me ka leukemia myelomonosittic maʻi mau (CMML) i nā mākua. Aia ʻo Decitabine i kahi papa o nā lāʻau i kapa ʻia he mau mea hana hypomethylation. Hana ia ma ke kōkua ʻana i ka momona o ka iwi e hana i nā hunaola kūlohelohe a me ka luku ʻana i nā hunaola kūpono ʻole i ka iwi iwi. Aia ʻo Cedazuridine i loko o ka papa o nā lāʻau i kapa ʻia he mau mea kūpale cytidine deaminase. Kōkua ia e hoʻonui i ka nui o decitabine i loko o ke kino i mea e ʻoi aku ka hopena o ka lāʻau.

ʻO ka hui pū ʻana o decitabine a me cedazuridine e hele mai ana ma ke ʻano he papa e lawe ʻia e ka waha. Lawe pinepine ʻia ia ma ka ʻōpū hakahaka no nā lā mua 5 o ka pōʻaiapuni 28 mau lā. Mai ʻai i ka meaʻai no 2 mau hola ma mua a me 2 mau hola ma hope o kēlā me kēia kau. E hana hou paha ke ʻano pōʻaiapuni 28 mau lā e like me ka ʻōlelo a kou kauka e pili ana i ka pane o kou kino i kēia lāʻau. Pono e hāʻawi ʻia i ka mālama ʻana ma ka liʻiliʻi he 4 mau pōʻaiapuni akā e hoʻomau ʻia paha inā hoʻoholo kāu kauka e pōmaikaʻi ʻoe i nā lāʻau hou aʻe.

E ale i nā papa holoʻokoʻa; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou.

Inā ʻoe e luaʻi ma hope o ka lawe ʻana i ka decitabine a me ka cedazuridine, mai lawe i kahi lāʻau ʻē aʻe. E hoʻomau i kāu papa hana maʻamau.

E hāʻawi aku kāu kauka iā ʻoe i ka lāʻau e pale ai i ka nausea a me ka luaʻi ma mua o kou loaʻa ʻana i kēlā me kēia kau o decitabine a me cedazuridine.

Hiki i kāu kauka ke hōʻemi i kāu lāʻau a i ʻole manawa kūmau a paʻa mau paha i kāu lāʻau inā ʻike ʻoe i kekahi mau hopena ʻaoʻao. E haʻi pono i kāu kauka i kou ʻano i kou wā e mālama ai me decitabine a me cedazuridine.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka decitabine a me ka cedazuridine,

• e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka decitabine, cedazuridine, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa decitabine a me cedazuridine. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa paha iā ʻoe ka maʻi puʻuwai a i ʻole ate.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai i ka hāpai ʻana, a inā ʻoe e hoʻolālā e makua kāne i kahi keiki. Inā he wahine ʻoe, pono ʻoe e lawe i kahi hōʻike hāpai keiki ma mua o kou hoʻomaka ʻana i ka lāʻau lapaʻau a hoʻohana i ka kaohi hānau e pale ai i ka hāpai ʻana i kāu wā lapaʻau a no 6 mau mahina ma hope o kāu hopena hope loa. Inā he kāne ʻoe, pono ʻoe a me kāu pakanā wahine e hoʻohana i ka kaohi hānau pono ke lawe ʻoe i decitabine a me cedazuridine a no 3 mau mahina ma hope o ka hopena hope loa. Inā hāpai ʻoe a ʻo kāu hoa paha i ka lawe ʻana i kēia lāʻau, e kāhea i kāu kauka. Hiki i ka Decitabine a me ka cedazuridine ke hōʻeha i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. Mai hānai i ka wā e lawe ana ʻoe i ka decitabine a me ka cedazuridine a no 2 mau pule ma hope o kāu hopena hope loa.
• pono ʻoe e ʻike i kēia lāʻau i hoʻemi ai i ka momona i nā kāne. E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka lawe ʻana i decitabine a me cedazuridine.
• inā ke ʻoki nei ʻoe, e like me ke ʻoki niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i ka decitabine a me ka cedazuridine.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

Inā ua emi ma mua o 12 mau hola mai kou manawa i hoʻonohonoho ʻia e lawe i ka lāʻau, lawe i ka lāʻau i hala ma ka ʻōpū hakahaka ke hoʻomanaʻo ʻoe iā ia. Inā ʻoi aku ma mua o 12 mau hola, e lele i ka lāʻau i haʻalele ʻia a hoʻomau i kāu papa hana maʻamau maʻamau e hoʻopau ai i nā koina 5 o kēlā me kēia lā i ka pōʻaiapuni. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hiki i ka Decitabine a me ka cedazuridine ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• luhi nui loa
• ʻili mae
• kōpaʻa
• pāhoehoe
• nausea
• ka luaʻi
• ʻeha ka ʻōpū
• Kaumaha emi
• nalo ʻai ʻole
• ʻeha hui a ʻeha ʻeha paha
• ʻūpā
• hāʻule ʻana i lalo
• ʻeha poʻo
• paʻakikī e hiamoe a hiamoe paha
• ʻehaʻeha ma ka waha, a i ka alelo a i ʻole nā ​​lehelehe
• pehu o nā lima, nā wāwae, nā kuʻekuʻe wāwae, nā wāwae lalo, a i ʻole ka ʻōpū
• ʻūlū, numbness, a ʻeha ma nā lima a me nā wāwae

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• ke kuni, ke anu, ka ʻū, ka ʻeha o ke kino, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
• kahe ʻole a kahe ʻana o ka ihu, kahe ka ihu, a i ʻole ke kahe o ke kahe
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• pokole o ka hanu
• hūwī

Hiki i ka Decitabine a me ka cedazuridine ke kumu i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab a ma mua a i kāu wā e mālama ai e nānā i ka pane o kou kino i decitabine a me cedazuridine.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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