Cladribine

Anter

• Ma mua o ka lawe ʻana i ka cladribine,
• Hoʻokumu paha ʻo Cladribine i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hiki i ka Cladribine ke hoʻonui i ka makaʻu e hoʻomohala ʻoe i ka maʻi ʻaʻai. E haʻi i kāu kauka inā loaʻa ʻoe i ka maʻi ʻaʻai. E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka cladribine.E kamaʻilio me kāu kauka e pili ana i ka mea āu e hana ai e nānā i nā hōʻailona o ka maʻi ʻaʻai e like me ka hoʻāʻo ʻana iā ʻoe iho a me nā hōʻike loiloi ʻana.

E kamaʻilio me kāu kauka e pili ana i ka makaʻu i ka lawe ʻana i ka cladribine.

Mai lawe i ka cladribine inā hāpai ʻoe a hoʻolālā paha e hāpai. Inā hāpai ʻoe i ka lawe ʻana i ka cladribine, e hoʻōki i ka lawe ʻana i ka cladribine a kāhea koke aku i kāu kauka. Aia kekahi makaʻu i hiki i ka cladribine ke kumu o ka nalo ʻana o ka hāpai keiki a i ʻole e hoʻokumu ʻia ka pēpē me nā kīnā hānau (nā pilikia o ke kino i ka wā hānau).

E nānā kāu kauka inā he hāpai ʻoe ma mua o kou hoʻomaka ʻana i kēlā me kēia papa o ka mālama. Pono ʻoe e hoʻohana i ka kaohi hānau e pale ai i ka hāpai ʻana i kēlā me kēia papa o ka mālama ʻana me cladribine a no ʻeono mau mahina ma hope o kāu kau hope loa o kēlā me kēia papa hana. Inā ʻoe e hoʻohana ana i nā mea pale hormonal (estrogen) (nā lāʻau kaohi o ka hānau ʻana, nā pāhoʻi, nā apo, nā implants, a i ʻole nā ​​injection) pono ʻoe e hoʻohana i kekahi ʻano hana o ka kaohi hānau i kēlā me kēia papa hana me ka cladribine a no 4 mau pule ma hope o kāu hopena hope loa o kēlā me kēia papa hana. Inā he kāne ʻoe me kāu hoa wahine i hiki ke hāpai, e hoʻomaopopo e hoʻohana i ka kaohi hānau i kēlā me kēia papa o ka mālama ʻana me cladribine a no ʻeono mau mahina ma hope o kāu mahele hope loa o kēlā me kēia papa hana. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana hānau hiki iā ʻoe ke hoʻohana i ka wā a ma hope o kāu lapaʻau.

E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka palapala ʻikepili a ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me cladribine a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

Hoʻohana ʻia ʻo Cladribine e mālama i nā mākua me nā ʻano hou o nā sclerosis he nui (MS; kahi maʻi kahi e holo pono ʻole ai nā ʻalolo a ʻike paha ka poʻe i ka nāwaliwali, numbness, nalo ʻana o ka coordination o nā mākala, a me nā pilikia me ka hihi, kamaʻilio, a me ka mālama ʻana i ka maʻi ʻaʻa), me nā palapala remapsing remitting (papa o ka maʻi kahi e piʻi ai nā ʻōuli mai kēlā me kēia manawa) a me nā ʻano holomua holomua ʻelua (papa o ka maʻi e ukali ana i kahi papa remapsing-remitting kahi e hele a hewa ai nā ʻōuli i ka manawa). Hoʻohana ʻia ʻo Cladribine i nā mea maʻi i hoʻāʻo mua i kahi lāʻau hou no MS. ʻO Cladribine i loko o ka papa o nā lāʻau i kapa ʻia purine antimetabolites. Hana ia ma ke kāpae ʻana i kekahi mau pūnaewele o ka ʻōnaehana pale maʻi mai ke kumu o ka hōʻino ʻana o nā aʻa.

Hele mai ʻo Cladribine ma ke ʻano he papa e lawe ma ka waha me ka wai. Lawe ʻia ia me ka ʻole o ka meaʻai, hoʻokahi manawa i ka lā no 4 a 5 mau lā i ka lālani no hoʻokahi pōʻai hoʻomaʻamaʻa. Pono e hana hou i kahi pōʻai hoʻomaʻamaʻa 23 a 27 mau lā ma hope e hoʻopau i hoʻokahi papa hana. Hāʻawi pinepine ʻia kahi papa ʻelua (2 pōʻaiapuni lapaʻau) ma ka liʻiliʻi he 43 mau pule ma hope o ka hopena hope o ka pōʻaiapili ʻelua. E lawe i ka cladribine ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe pololei i ka cladribine e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa holoʻokoʻa; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou.

Wehe i ka papa mai ka pahu blister me nā lima maloʻo a laila e ale koke i ka papa. E kaupalena i ka manawa o ka papapa i ka pilina me kou ʻili. Hōʻalo i ka hoʻopā ʻana i kou ihu, nā maka, a me nā ʻāpana ʻē aʻe o kou kino. Ma hope o kou lawe ʻana i ka lāʻau, holoi maikaʻi i kou mau lima me ka wai. Inā pili ka papa me nā papa a i ʻole nā ​​ʻāpana ʻē aʻe o kou kino, holoi pū iā lākou me ka wai koke.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka cladribine,

• e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka cladribine, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o nā papa cladribine. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, a me nā mea hoʻopihaʻai pono ʻole āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: cilostazol; dipyridamole (Persantine, i Aggrenox); elrombopag (Promacta); furosemide (Lasix); gabapentin (Gralise, Horizant, Neurontin); ibuprofen (Advil, Midol, Motrin, nā mea ʻē aʻe); interferon beta (Avonex, Betaseron, Extavia, Rebif); lamivudine (Epivir, i Epzicom); nā lāʻau e kāohi i ka ʻōnaehana pale e like me azathioprine (Azasan), cyclosporine (Gengraf, Neoral, Sandimmune), methotrexate (Otrexup, Rasuvo, Trexall, Xatmep), sirolimus (Rapamune), a me tacrolimus (Astagraf, Envarsus, Prograf); nifedipine (Adalat, Procardia); nimodipine (Nymalize); reserpine; ribavirin (Rebetol, Ribasphere, Virazole); rifampin (Rifadin, Rimactane, ma Rifamate, ma Rifater); ritonavir (Norvir, ma Kaletra, ma Technivie, ma Viekira); stavudine (Zerit); nā steroid e like me dexamethasone (Decadron, Dexpak), methylprednisolone (Medrol), a me prednisone (Rayos); sulindac; a me zidovudine (Retrovir, ma Combivir, ma Trizivir). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me cladribine, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• inā ʻoe e lawe i nā lāʻau ʻē aʻe ma ka waha, e lawe iā lākou i 3 mau hola ma mua a i ʻole 3 mau hola ma hope o cladribine.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, keu hoʻi i ka curcumin a me ka wort o St.
• e haʻi aku i kāu kauka inā loaʻa iā ʻoe kahi maʻi pale maʻi (HIV), hepitis (he maʻi hoʻomaʻi e hoʻopili ana i ke akepaʻa a e hōʻeha paha i ke ake), tuberculosis (TB; kahi maʻi nui e pili ana i nā akemāmā a i kekahi manawa nā ʻāpana o ke kino), a i ʻole nā maʻi ʻē aʻe e mau ana. E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka cladribine.
• e haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ke ake, ka hakuʻala, a i ʻole ka maʻi puʻuwai.
• e haʻi i kāu kauka inā ʻoe e hānai umauma ana. ʻAʻole pono ʻoe e hānai i ka hānai i ka wā o ka pōʻaiapuni, a no 10 mau lā ma hope o ka hopena hope loa o ke kaapuni lapaʻau.
• inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o nā niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i ka cladribine.
• ʻaʻohe o nā lāʻau āpau ma waena o 4 a 6 mau pule ma mua, i ka manawa, a ma hope paha o kāu mālama ʻana me cladribine me ke kamaʻilio ʻole ʻana me kāu kauka. E kamaʻilio me kāu kauka inā pono ʻoe e loaʻa i nā lāʻau āpau ma mua o kou hoʻomaka ʻana i kāu lāʻau.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala ma hope ke hoʻomanaʻo ʻoe ia i ka lā like. Eia naʻe, inā ʻaʻole ia e lawe i ka lā i hoʻopaʻa ʻia, a laila e lawe i ka lāʻau i hala i ka lā aʻe a e hoʻohui i kekahi lā i kēlā pōʻaiapuni. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Cladribine i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• ʻeha poʻo
• nausea
• ʻeha kua
• ʻeha puʻupuʻu a me ka ʻoʻoleʻa
• paʻakikī e hiamoe a hiamoe paha
• kaumaha
• poho lauoho
• ʻalalā, ʻili, a ʻeha paha i nā gum, nā lehelehe, a me nā waha

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• fiva, ʻāʻī puʻupuʻu, ʻalalā, ʻeha a ʻeha hoʻi i nā mākala, ʻeha, a me nā hōʻailona ʻē aʻe o ka maʻi
• ʻeha, ʻeha o ka umauma, ʻūlū i ke koko a i ʻole ka mucus, nāwaliwali a luhi paha, ka pohō o ke kaumaha, nalo o ka makemake, nā anuanu, ke kuni, ka hou a ka pō.
• ʻehaʻeha me ka palapū
• ʻā ʻana, ʻalalā ʻana, ʻōpala, a i ʻole itchiness o ka ʻili
• ʻehu, paʻakikī i ka hanu ʻana a me ka ale ʻana, ka pehu ʻana a i ʻole ka ʻeha ʻana o ka maka, nā lehelehe, nā alelo, a me ka ʻāʻī
• ʻO ke anuanu, ke kuni, ka luʻuluʻu, ka luaʻi, ʻeha ma kou kua, ʻaoʻao, a ʻeha paha, urination pinepine a ʻeha hoʻi
• kahe koko ʻole ʻana a palapū paha
• nāwaliwali ma kekahi ʻaoʻao o kou kino, nalowale o ka hoʻohui ʻana i kou mau lima a i ʻole nā ​​wāwae, hoʻemi i ka ikaika, nā pilikia me ke kaulike, huikau, nā loli i kāu ʻike, noʻonoʻo, hoʻomanaʻo, a ʻano pilikino paha.
• ka pōkole o ka hanu, ka wikiwiki o ka puʻuwai, ka ʻeha o ke poʻo, ka luhi, ka ʻili ʻula, ka huikau, ka luhi
• nausea, luaʻi, luhi nui loa, nalo o ka makemake ʻole, ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū, melemele o ka ʻili a me nā maka, mimi ʻeleʻele
• ka pōkole o ka hanu, ka wikiwiki a i ʻole ka puʻuwai o ka puʻuwai, kūhū i kahi ʻāpana o kou kino

Hoʻokumu paha ʻo Cladribine i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Mālama i nā koho āpau me kou kauka a me ka hale hana. E kauoha aku kāu kauka i kekahi mau hoʻokolohua ma mua, i ka wā, a ma hope o kāu mālama ʻana e hōʻoia he palekana no ʻoe e lawe i ka cladribine a e nānā i ka pane o kou kino i ka cladribine.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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