Hoʻomoʻo Ravulizumab-cwvz

Anter

• Ma mua o ka loaʻa ʻana o ka injection ravulizumab-cwvz,
• Hiki i nā Ravulizumab-cwvz ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo AOAO IMAHI a i ʻole KĀʻĀLĀ ʻĀpana, e kāhea koke aku i kāu kauka a i ʻole e kiʻi i nā lāʻau lapaʻau pilikia.

ʻO ka loaʻa ʻana o ka inikua ravulizumab-cwvz hiki ke hoʻonui i ka makaʻu e hoʻomohala ʻoe i kahi maʻi meningococcal (kahi maʻi i hiki ke hoʻopili i ka uhi ʻana o ka lolo a me ka iwi kuamoʻo a / a i ʻole pāhola paha ma o ke kahe o ke koko) i kāu wā e lapaʻau ai a i ʻole no kekahi manawa ma hope. Hiki i nā maʻi Meningococcal ke make i loko o kahi manawa pōkole. Pono ʻoe e loaʻa i kahi lāʻau lapaʻau meningococcal ma ka liʻiliʻi he 2 mau pule ma mua o kou hoʻomaka ʻana i kāu lāʻau me ka pahu ʻana ravulizumab-cwvz e hoʻemi i ka makaʻu e hoʻomohala ʻoe i kēia ʻano maʻi. Inā ua loaʻa iā ʻoe kēia lāʻau lapaʻau i ka wā ma mua, pono paha ʻoe e loaʻa i kahi lāʻau booster ma mua o kou hoʻomaka ʻana i kāu lāʻau. Inā manaʻo kāu kauka pono ʻoe e hoʻomaka i ka hoʻoponopono ʻana me ka injection ʻo ravulizumab-cwvz koke, e loaʻa koke iā ʻoe kāu lāʻau lapaʻau meningococcal a lawe i kahi antibiotic no 2 mau pule.

ʻOiai inā loaʻa iā ʻoe ka lāʻau lapaʻau meningococcal, aia nō kahi makaʻu e hoʻomohala ʻoe i ka maʻi meningococcal i ka manawa a ma hope paha o kāu lapaʻau ʻana me ka injection ravulizumab-cwvz. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka a i ʻole e loaʻa i ke kōkua olakino pōpilikia: ʻeha ke poʻo e hele pū me ka nausea a i ʻole ka luaʻi, ke kuni, kahi ʻāʻī ʻoʻoleʻa, a me kahi kua ʻoʻoleʻa. kuni; hū a me ka wela; huikau; ʻeha nā mākala a me nā hōʻailona like like me ka flu; aiʻole inā pili kou mau maka i ka mālam.

E haʻi i kāu kauka inā he kuni kou a i ʻole nā ​​hōʻailona ʻino ʻē aʻe ma mua o kou hoʻomaka ʻana i kāu lāʻau lapaʻau me ka injection ʻo ravulizumab-cwvz. ʻAʻole hāʻawi kāu kauka iā ʻoe i ka werulizumab-cwvz injection inā he maʻi maʻi meningococcal kāu.

E hāʻawi aku kāu kauka iā ʻoe i kahi kāleka palekana ahonui me ka ʻikepili e pili ana i ka makaʻu o ka ulu ʻana i ka maʻi meningococcal i loko a i ʻole no kekahi manawa ma hope o kāu lapaʻau ʻana. Lawe i kēia kāleka me ʻoe i nā manawa āpau i kāu mālama ʻana a no 8 mau mahina ma hope o kāu lapaʻau. Hōʻike i ke kāleka i nā lawelawe mālama ola āpau nāna e mālama iā ʻoe i ʻike lākou e pili ana i kāu pilikia.

Ua hoʻonohonoho ʻia kahi papahana i kapa ʻia ʻo Ultomiris REMS e hoʻoliʻiliʻi i nā makaʻu o ka loaʻa ʻana o ka injulizumab-cwvz injection. Hiki iā ʻoe ke loaʻa wale iā injulizumab-cwvz injection mai ke kauka i komo i kēia papahana, ua kamaʻilio pū me ʻoe e pili ana i nā pilikia o ka maʻi meningococcal, hāʻawi iā ʻoe i kahi kāleka palekana hoʻomanawanui, a ua hōʻoia ua loaʻa iā ʻoe kahi lāʻau lapaʻau meningococcal.

E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka palapala ʻike hoʻomanawanui a ka mea hana (Ke alakaʻi lāʻau) ke hoʻomaka ʻoe i ka lāʻau me ravulizumab-cwvz a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

E kamaʻilio me kāu kauka e pili ana i ka makaʻu o ka loaʻa ʻana o ka inikua ravulizumab-cwvz.

Hoʻohana ʻia ka injection ʻo Ravulizumab-cwvz i ka poʻe mākua e mālama i ka hemoglobinuria o paroxysmal nocturnal (PNH: kahi ʻano anemia kahi i haki ʻia ai nā hunaola ʻulaʻula i loko o ke kino, no laila ʻaʻole lawa nā pūnaewele olakino e lawe i ka oxygen i nā ʻāpana āpau o ke kino. ). Hoʻohana pū ʻia ʻo ka injection ʻo Ravulizumab-cwvz i nā mākua a me nā keiki ʻo 1 mau makahiki a ʻoi aku ka nui e mālama i ka maʻi hemolytic uremik atypical (aHUS; kahi ʻano hoʻoilina kahi e hana ai ke koko liʻiliʻi i loko o ke kino a e hōʻino paha i nā kīʻaha koko, nā huna koko, nā puʻupaʻa, a me nā ʻāpana ʻē aʻe o ke kino). Aia ʻo Ravulizumab-cwvz i kahi papa o nā lāʻau i kapa ʻia he monoclonal antibodies. Hana ia ma ke kāpae ʻana i ka hana o ka ʻāpana o ka ʻōnaehana pale e hōʻino ai i nā hunaola o ke koko i nā poʻe me PNH a ke kumu e hana i nā clots i nā kānaka me aHUS.

Hele mai ka injection ʻo Ravulizumab-cwvz ma ke ʻano he hopena (wai) e ʻimi ʻino ʻia (i loko o kahi aa) ma kahi o 2-4 mau hola e ke kauka a kahu hānai paha i kahi keʻena lapaʻau. Hāʻawi pinepine ʻia kēlā me kēia 8 mau pule e hoʻomaka ana i 2 mau pule ma hope o kāu kau mua. Hiki i nā keiki ke loaʻa i ka injection ravulizumab-cwvz i kēlā me kēia 4 a i ʻole 8 mau pule, e like me ke kaumaha o ke kino, e hoʻomaka ana i 2 mau pule ma hope o ka lāʻau mua.

Hiki paha i ka injection ʻo Ravulizumab-cwvz ke hana i nā hopena maʻi kūpilikiʻi. E nānā pono kāu kauka iā ʻoe ke loaʻa ʻoe i ka werulizumab-cwvz injection a no 1 hola ma hope o kou loaʻa ʻana i ka lāʻau. Lohi paha kāu kauka i kāu infusion inā loaʻa ʻoe i kahi hopena maʻi ʻaʻa. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e haʻi koke i kāu kauka: ʻeha o ka umauma; paʻakikī i ka hanu ʻana; pokole o ka hanu; pehu o kou alo, elelo, a puʻu paha; ʻeha ʻeha o lalo; ʻeha me ka infusion; a maʻule paha.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka loaʻa ʻana o ka injection ravulizumab-cwvz,

• e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ravulizumab-cwvz, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i ka inikua ravulizumab-cwvz. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, nā mea hoʻopihaʻai, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole kekahi maʻi olakino ʻē aʻe.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. Inā hāpai ʻoe i ka loaʻa ʻana o ka inikua ravulizumab-cwvz, e kāhea i kāu kauka.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. ʻAʻole pono ʻoe e hānai i ka wā e loaʻa ana iā ravulizumab-cwvz a no 8 mau mahina ma hope o kāu hopena hope loa.
• inā mālama ʻia ʻoe no PNH, pono ʻoe e ʻike ʻo kou maʻi ke kumu o ka haki ʻana o nā hunaola ʻulaʻula ma hope o kou kū ʻana i ka loaʻa ʻana o ka inikū ravulizumab-cwvz. E nānā pono kāu kauka iā ʻoe a kauoha paha i nā hoʻokolohua hale hana no 16 mau pule ma hope o kou hoʻopau ʻana i kāu lāʻau. Kāhea koke aku i kāu kauka inā hoʻomōhala ʻoe i kekahi o nā ʻōuli ma lalo iho nei: luhi loa; ke koko i ka mimi; ʻeha ka ʻōpū; pilikia i ka ale ʻana; hiki ʻole ke kiʻi a mālama i ke kūkulu ʻana; pokole o ka hanu; ʻeha, pehu, hoʻomehana, ʻulaʻula, a palupalu paha i ka wāwae hoʻokahi wale nō; lohi a paʻakikī paha i ka ʻōlelo; ka nāwaliwali a i ʻole ka helu ʻana o ka lima a me ka wāwae; a i ʻole nā ​​ʻōuli ʻē aʻe.
• inā mālama ʻia ʻoe no aHUS, pono ʻoe e ʻike ʻo kou ʻano ke kumu e hana i nā kahe koko i kou kino ma hope o kou kū ʻole ʻana i ka werulizumab-cwvz injection. E nānā pono kāu kauka iā ʻoe a kauoha paha i nā hoʻokolohua hale hana no 12 mau mahina ma hope o kou hoʻopau ʻana i kāu lāʻau. Kāhea koke aku i kāu kauka inā hoʻomohala ʻoe i kekahi o nā ʻōuli penei: ka pilikia hikiwawe i ka ʻōlelo ʻana a i ʻole ka hoʻomaopopo ʻana i ka ʻōlelo, ka pioloke, ka nāwaliwali koke a i ʻole ka helu ʻana o ka lima a me ka wāwae (ʻoi loa ma kekahi ʻaoʻao o ke kino) a i ʻole o ka helehelena, pilikia hele wāwae koke puʻupuʻu, nalo ʻana o ke kaulike a i ʻole ka hoʻohui ʻana, maʻule ʻana, hopu ʻana, ka ʻeha o ka umauma, paʻakikī ka hanu ʻana, a i ʻole nā ​​hōʻailona ʻē aʻe ʻē aʻe.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

Inā ʻoe e nalo i kahi manawa e loaʻa ai kahi lāʻau o ravulizumab-cwvz injection, e kelepona koke i kāu kauka.

Hiki i nā Ravulizumab-cwvz ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• pāhoehoe
• nausea
• ka luaʻi
• kōpaʻa
• ʻeha poʻo
• ʻehaʻeha a ʻeha pū paha
• ʻeha ma nā lima a me nā wāwae
• ihu ihope
• ʻeha a pehu paha i ka ihu a i ʻole ka puʻu
• ʻūhā
• ʻūpā
• ʻinoʻī paʻakikī a paʻakikī paha
• poho lauoho
• ʻili maloʻo
• hoʻēmi ʻai
• luhi

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo AOAO IMAHI a i ʻole KĀʻĀLĀ ʻĀpana, e kāhea koke aku i kāu kauka a i ʻole e kiʻi i nā lāʻau lapaʻau pilikia.

• fiva a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
• ʻeha ka ʻōpū

Hiki i ka Ravulizumab-cwvz ke hana i nā hopena ʻē aʻe. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau i ka loaʻa ʻana o kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka inikua ravulizumab-cwvz.

E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka werikizumab-cwvz injection.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Ultomiris^®