Ixazomib

Anter

• Ma mua o ka lawe ʻana iā ixazomib,
• Hoʻokumu paha ʻo Ixazomib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli e kāhea koke i kāu kauka:

Hoʻohana ʻia ʻo Ixazomib me ka lenalidomide (Revlimid) a me dexamethasone e mālama i nā myeloma he nui (ka maʻi ʻaʻai o nā hunaola plasma i ka iwi iwi) i māhuahua ma hope o ka lapaʻau ʻana me nā lāʻau chemotherapy ʻē aʻe. Aia ʻo Ixazomib i kahi papa o nā lāʻau i kapa ʻia nā proteasome inhibitors. Hana ia ma ke kōkua ʻana e luku i nā hunaola maʻi ʻaʻai.

Hele mai ʻo Ixazomib ma ke ʻano he capsule e lawe ma ka waha. Lawe pinepine ʻia me ka wai ma kahi ʻōpū hakahaka, ma ka liʻiliʻi he 1 hola ma mua a i ʻole 2 mau hola ma hope o ka ʻai ʻana. Lawe ʻia ia i nā lā 1,8, a me 15 o ka pōʻaiapuni lā he 28 lā. Lawe iā ixazomib ma kahi o ka manawa like i kēlā me kēia lā āu e lawe ai. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe iā ixazomib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

Mai lawe i ka ixazomib a me ka dexamethasone i ka manawa like no ka mea pono ʻoe e lawe i ka dexamethasone me ka meaʻai.

E ale i nā capsule holoʻokoʻa; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou.

E akahele i ka lawelawe ʻana i nā capsule ixazomib. Mai ʻae i kou ʻili, maka, waha, a ihu paha e launa me nā capsules i wāwahi ʻia a haki paha. Inā kū kēlā pilina, holoi maikaʻi i kou ʻili me ke kopa a me ka wai a holoi maikaʻi paha i kou mau maka me ka wai maʻamau.

Inā luaʻi ʻoe ma hope o ka lawe ʻana i ka ixazomib, mai hana hou i ka lāʻau. E lawe i kāu mahele lāʻau hou o ixazomib i ka lā i hoʻopaʻa ʻia e manaʻo ʻia e lawe ia.

Pono paha kāu kauka e hoʻopau i kahi manawa kūlohelohe a paʻa paha i kāu lāʻau lapaʻau a hoʻoliʻiliʻi paha i kāu lāʻau o ka ixazomib, a i ʻole nā ​​lāʻau ʻē aʻe āu e lawe nei, e pili ana i nā hopena āu e ʻike ai. E kamaʻilio pono i kāu kauka e pili ana i kou ʻano i kou wā e mālama ai. Mai hōʻoki i ka lawe ʻana iā ixazomib me ke kamaʻilio ʻole ʻana me kāu kauka.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana iā ixazomib,

• e haʻi aku i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka ixazomib, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o ka capsules ixazomib. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi aku i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, nā mea hoʻopihaʻaiʻai āu e lawe nei a hoʻolālā paha e lawe. E hōʻike pono i kekahi o kēia mau mea: carbamazepine (Epitol, Equetro, Carbatrol, Tegretol, Teril), efavirenz (Sustiva, ma Atripla), nevirapine (Viramune), phenobarbital, pioglitazone (Actos, i Actoplus, Duetact, Oseni), phenyto (Dilantin, Phenytek), rifabutin (Mycobutin), a me rifampin (Rifadin, Rimactane, ma Rifamate, Rifater). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
• e haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi ate a me nā puʻupaʻa.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai i ka hāpai ʻana, a i ʻole hoʻolālā i ka makua kāne o kahi keiki. ʻAʻole pono ʻoe e hāpai i ka wā e lawe ana ʻoe i ka ixazomib. E hoʻohana i ka kaohi hānau kūpono i kāu mālama ʻana me ixazomib a no 90 mau lā ma hope o kāu hopena hope loa. Inā he kāne ʻoe a hiki i kāu pakanā ke hāpai, pono ʻoe e hoʻohana i ka kaohi hānau pono i kou wā e mālama ai a no 90 mau lā ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā hana kaohi hānau e holo pono nāu. Inā hāpai ʻoe a ʻo kāu hoa paha i ka lawe ʻana iā ixazomib, e kāhea koke i kāu kauka. Hiki iā Ixazomib ke hōʻeha i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. ʻAʻole pono ʻoe e hānai i ka wā e lawe ana ʻoe i ka ixazomib.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai.Eia nō naʻe, inā aia ma loko o 72 mau hola (3 mau lā) o kāu kau palena papala aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Ixazomib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• pāhoehoe
• kōpaʻa
• nausea
• wīwī hou a ʻoi paha
• ʻeha kua
• ka pehu ʻana o kou mau lima a me kou mau wāwae
• loaʻa ke kaupaona ma muli o ka pehu
• ʻike hihi
• maka maloʻo
• maka ʻākala

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli e kāhea koke i kāu kauka:

• nausea
• luhi loa
• nalo ʻai ʻole
• nā ʻōuli like flu
• kahe koko ʻole ʻana a palapū paha
• melemele o kou ʻili a mau maka paha
• ʻeha ma ka ʻaoʻao ʻākau o luna o kou ʻōpū
• ka wela, ke kaniʻuhū, ka helu, ka ʻeha, a nāwaliwali paha i nā lima a me nā wāwae
• koko a ʻeleʻele paha, noho humuhumu

Hoʻokumu paha ʻo Ixazomib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua. E waiho i ka lāʻau i loko o ka waihona mua a hiki i ka pono ma mua o kou lawe ʻana.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino iā ixazomib.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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