Pembrolizumab Injection

Anter

• Hoʻohana ʻia ka injection Pembrolizumab: aia ka injection injection Pembrolizumab i loko o ka papa o nā lāʻau i kapa ʻia he monoclonal antibodies. Hana ia ma ke kōkua ʻana i kāu ʻōnaehana pale e hoʻolohi a kū i ka ulu ʻana o nā hunaola maʻi ʻaʻai.
• Ma mua o ka loaʻa ʻana o ka injection injection pembrolizumab,
• Hiki i ka injection injection Pembrolizumab ke kumu i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hoʻohana ʻia ka injection Pembrolizumab: aia ka injection injection Pembrolizumab i loko o ka papa o nā lāʻau i kapa ʻia he monoclonal antibodies. Hana ia ma ke kōkua ʻana i kāu ʻōnaehana pale e hoʻolohi a kū i ka ulu ʻana o nā hunaola maʻi ʻaʻai.

• e mālama i ka melanoma (kahi ʻano o ka maʻi ʻaʻai ʻili) ʻaʻole hiki ke mālama ʻia me ke ʻoki ʻana a i ʻole pāhola ʻia i nā ʻāpana ʻē aʻe o ke kino, a i ʻole me ka hui pū ʻana me nā lāʻau chemotherapy e mālama a pale ai i ka hoʻi ʻana o melanoma ma hope o ke kaha ʻana e hoʻoneʻe iā ia a me nā lymph āpau nā pona;
• e mālama i kekahi ʻano o ka maʻi ʻaʻai liʻiliʻi liʻiliʻi ʻole (NSCLC) ʻaʻole hiki ke mālama ʻia me ke kaha ʻana, nā lāʻau chemotherapy ʻē aʻe, a i ʻole radiation therapy a i ʻole pālahalaha ʻia i nā ʻāpana ʻē aʻe o ke kino a i ʻole worsened i ka wā a ma hope paha o ka mālama ʻia ʻana me ka platinum i loaʻa nā lāʻau chemotherapy (cisplatin, carboplatin), a i ʻole me ka hoʻohui ʻia me nā lāʻau chemotherapy (paclitaxel, pemetrexed) e mālama i kekahi ʻano o ka NSCLC i pāhola ʻia i nā ʻāpana ʻē aʻe o ke kino;
• e mālama i kekahi ʻano maʻi poʻo o ke poʻo a me ka ʻāʻī e hoʻi mau nei a i ʻole ua laha i nā ʻāpana ʻē aʻe o ke kino a ʻaʻole hiki ke hemo e ke ʻoki. Hiki nō ke hoʻohana pū ʻia me ka fluorouracil a me ka platinum i loaʻa i nā lāʻau chemotherapy (cisplatin, carboplatin) e mālama ai i kekahi ʻano maʻi poʻo a me nā ʻāʻī o ka ʻāʻī e hoʻi mau nei a ua laha paha i nā ʻāpana ʻē aʻe o ke kino a ʻaʻole hiki ke mālama ʻia me ke ʻoki. Hoʻohana pū ʻia ʻo Pembrolizumab e mālama i kekahi ʻano o ke poʻo a me ka ʻāʻī o ka ʻāʻī i ʻino a pāhola paha i nā ʻāpana ʻē aʻe o ke kino i ka wā a ma hope paha o ka mālama ʻana me nā lāʻau chemotherapy;
• e mālama i kekahi ʻano o ka lymphoma o Hodgkin (ka maʻi ʻo Hodgkin) i nā keiki a me nā mākua ʻaʻole i ʻoi aku ka maikaʻi me nā lāʻau chemotherapy ʻē aʻe a i ʻoi aku ka maikaʻi akā hoʻi mai ma hope o ka mālama ʻana me nā lāʻau chemotherapy ʻē aʻe a me nā keiki ma hope o ka mālama ʻia ʻana i ʻelua a ʻoi mau manawa me nā lāʻau chemotherapy ʻē aʻe. ;
• e mālama i kekahi ʻano o ka lymphoma B-cell mediastinal mua (PMBCL; non-Hodgkin lymphoma) i nā keiki a me nā mākua i maikaʻi ʻole me nā lāʻau chemotherapy ʻē aʻe a i hoʻihoʻi ʻia paha ma hope o ka mālama ʻia ʻana i ʻelua a ʻoi mau manawa me nā lāʻau chemotherapy ʻē aʻe;
• e mālama i kekahi ʻano maʻi ʻaʻai urothelial (ka maʻi ʻaʻai o ka pale o ka maʻi ʻaʻai a me nā ʻāpana ʻē aʻe o ka maʻi urinary) i pālahalaha ʻia i nā mea kokoke a i ʻole nā ​​ʻāpana ʻē aʻe o ke kino i ka poʻe i hiki ʻole ke loaʻa i ka platinum i loaʻa nā lāʻau chemotherapy (cisplatin, carboplatin) , a i ʻole ʻo wai ka maʻi maʻi i hoʻomāhuahua i ka wā a ma hope paha o ka mālama ʻia ʻana me kēia mau lāʻau chemotherapy;
• e mālama i kekahi ʻano maʻi ʻaʻai o ka maʻi ʻaʻai i loko o ka poʻe ʻaʻole i ʻoi aku ka maikaʻi me kekahi lāʻau ʻē aʻe (Bacillus Calmette-Guerin; BCG therapy) a ʻaʻole hiki a i ʻole i hoʻoholo e hana ʻole ʻia e ke ʻoki ʻana e hemo ai ka pūpū.
• e mālama i kekahi ʻano o ka maʻi ʻaʻai kala (colorer i hoʻomaka i loko o ka ʻōpū nui) a me kekahi ʻano o nā tumors paʻa ma ke ʻano he lapaʻau mua i nā keiki a me nā mākua i hiki ʻole ke mālama ʻia e ke ʻoki a i pāhola paha i nā ʻāpana ʻē aʻe o ke kino a i ʻole i kēlā mau ua kaumaha ma hope o ka mālama ʻia ʻana me nā lāʻau chemotherapy ʻē aʻe;
• e mālama i kekahi ʻano o ka maʻi ʻaʻai gastric (ka maʻi ʻaʻai o ka ʻōpū) a i ʻole ke kanesa i ka wahi e hui ai ka ʻōpū me ka esophagus (ka paipu ma waena o ka ʻāʻī a me ka ʻōpū) i hoʻi mai a i pāhola paha i nā ʻāpana ʻē aʻe o ke kino i ka wā a ma hope paha 2 aʻoi aʻe paha nā hoʻoponopono chemotherapy;
• e mālama i kekahi ʻano o ka maʻi ʻaʻai esophageal i hoʻi mai a pāhola aku i nā aʻa kokoke a i ʻole nā ​​ʻāpana ʻē aʻe o ke kino ma hope o ka hoʻomaʻamaʻa ʻana me hoʻokahi a ʻoi aku paha nā lāʻau chemotherapy a ʻaʻole hiki ke mālama ʻia me ka ʻoki a me ka radiation radiation.
• e mālama i kekahi ʻano o ka maʻi ʻaʻai cerviera (ka maʻi ʻaʻai e hoʻomaka i ka wehe ʻana o ka ʻōpū [ʻōpū]) i hoʻi mai a i ʻole pāhola ʻia i nā ʻāpana ʻē aʻe o ke kino i ka wā a ma hope paha o ka mālama ʻana me kahi lāʻau chemotherapy ʻē aʻe;
• e mālama i kekahi ʻano o ka hepatocellular carcinoma (HCC; kahi ʻano maʻi ʻaʻai ate) i ka poʻe i mālama mua ʻole ʻia me sorafenib (Nexafar);
• e mālama iā Merkel cell carcinoma (MCC; kahi ʻano maʻi ʻaʻai o ka ʻili) i nā keiki a me nā mākua i hoʻi a pāhola i nā mea kokoke a i ʻole nā ​​ʻāpana ʻē aʻe o ke kino;
• i ka hui pū me ka axitinib (Inlyta) e mālama i ka carcinoma kōkō ʻoi loa holomua (RCC; kahi ʻano maʻi ʻaʻai e hoʻomaka i nā puʻupaʻa);
• i ka hui pū ʻana me lenvatinib (Lenvima) e mālama i kekahi ʻano maʻi ʻaʻai o ka endometrium (ka uhi ʻana o ka uterus) i pālahalaha ʻia i nā ʻāpana ʻē aʻe o ke kino a i ʻole worsened i ka wā a ma hope paha o ka mālama ʻana me nā lāʻau chemotherapy a i ʻole hiki ʻole ke mālama ʻia me ke ʻoki a me ka radiation hoʻōla;
• e mālama i kekahi ʻano o nā tumors paʻa i pālahalaha ʻia i nā ʻāpana ʻē aʻe o ke kino a i ʻole hiki ʻole ke mālama ʻia e ke ʻoki ʻana i nā mākua a me nā keiki i mālama ʻia me ka kūleʻa ʻole me kahi lāʻau chemotherapy ʻē aʻe a ʻaʻohe o nā koho lapaʻau maikaʻi ʻē aʻe;
• e mālama i kekahi ʻano o ka maʻi kanesa camous squamous cell carcinoma (CSCC; maʻi ʻaʻai ʻili) i hoʻi mai a i ʻole pālahalaha ʻia i nā ʻāpana ʻē aʻe o ke kino a ʻaʻole hiki ke mālama ʻia me ke ʻoki a me ka radiation radiation.
• a i ka hui pū ʻana me chemotherapy e mālama i kekahi ʻano o ka maʻi ʻaʻai o ka umauma i hoʻi i nā pūnaewele kokoke a ua pāhola paha i nā ʻāpana ʻē aʻe o ke kino a ʻaʻole hiki ke mālama ʻia me ke ʻoki kino.

Hele mai ʻo injection injection ʻo Pembrolizumab e like me ka pauka e hoʻopili ʻia me ka wai a injected i loko o ke aa (30) i loko o kahi vein ma 30 mau minuke e ke kauka a kahu hānai paha i kahi haukapila a i ʻole kahi wahi olakino. Hoʻomaʻamaʻa pinepine ʻia ia i kēlā me kēia 3 a i ʻole 6 mau pule no ka mea ke koi aku kāu kauka e loaʻa iā ʻoe ka lāʻau.

Hiki i ka injection injection Pembrolizumab ke kumu i nā hopena koʻikoʻi i ka wā, a i ʻole ma hope koke iho o ka hoʻopili ʻana o ka lāʻau. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e haʻi koke aku i kāu kauka: flushing, fever, chills, haʻalulu, hoʻoluhi, nāwaliwali, ka liʻiliʻi o ka hanu, paʻakikī i ka hanu ʻana, ka ʻū, ka ʻūlū, a me ka hives.

Hiki paha i kāu kauka ke hoʻolohi a hoʻopau paha i kāu lāʻau me ka inikuli pembrolizumab, a i ʻole mālama iā ʻoe me nā lāʻau hou aʻe, kaukaʻi ʻia i kāu pane i ka lāʻau a me nā hopena ʻē aʻe āu e ʻike ai. E kamaʻilio me kāu kauka e pili ana i kou ʻano i kāu mālama ʻana.

E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka pepa ʻikepili a ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me ka inikuli pembrolizumab a i kēlā me kēia manawa ke loaʻa iā ʻoe kahi lāʻau. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka loaʻa ʻana o ka injection injection pembrolizumab,

• e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka pembrolizumab, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hoʻohui i ka injection pembrolizumab. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka inā loaʻa iā ʻoe kahi ʻōpala a i ʻole ka iwi o ka iwi a inā ua loaʻa a ua loaʻa paha iā ʻoe kahi radiation therapy i kou umauma. kahi maʻi autoimmune (ke ʻano e hoʻouka ai ka ʻōnaehana pale i kahi ʻaoʻao olakino o ke kino) e like me ka maʻi o Crohn (ke ʻano e hoʻouka ai ka ʻōnaehana pale i ka uhi ʻana o ka tract digestive e hōʻeha ai i ka maʻi, diarrhea, weight loss, and fever), ulcerative colitis (ke kumu e hoʻonā ai i ka pehu a me nā ʻeha ma ke kaʻe o ke kolona [ʻōpū nui] a me ke kīhā), a i ʻole lupus (ke ʻano e hoʻouka aku ai ka ʻōnaehana pale i nā aʻa a me nā ʻola e like me ka ʻili, nā hono, ke koko, a me nā puʻupaʻa); mimikō; nā pilikia thyroid; kekahi ʻano maʻi maʻi a i ʻole nā ​​pilikia hanu; aiʻole ka maʻi puʻuwai a i ʻole ate.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. Pono ʻoe e lawe i kahi hōʻike hāpai ma mua o ka hoʻomaka ʻana i ka lāʻau. ʻAʻole pono ʻoe e hāpai i ka wā e loaʻa ana iā ʻoe ka lāʻau hoʻopunipuni pembrolizumab a no 4 mau mahina ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā hana kaohi hānau e holo pono nāu. Inā hāpai ʻoe i ka loaʻa ʻana o ka inikuli pembrolizumab, kāhea koke i kāu kauka. Hoʻopilikia paha ʻo injection iā Pembrolizumab i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū a i ʻole hoʻolālā e hānai. E haʻi paha kāu kauka iā ʻoe ʻaʻole e hānai i ka wā e loaʻa ana i ka inikuli pembrolizumab, a no 4 mau mahina ma hope o kāu hopena hope loa.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

Hiki i ka injection injection Pembrolizumab ke kumu i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• ʻeha hui a kua ʻeha paha
• pehu o ke kino a i ʻole ke alo
• nā hoʻololi i ke kala o ka ʻili
• luhi nui loa a nele paha i ka ikaika
• fiva
• nausea
• ka luaʻi

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• pālū a ʻiliʻili paha; ʻulaʻula ʻili; ʻehu; a ʻōwili paha
• ʻehaʻeha a ʻeha paha ma ka waha, ihu, ʻāʻī, a i ʻole genital area
• pokole o ka hanu
• ʻeha ka umauma
• ʻūhū hou a i ʻole worsening paha
• pāhoehoe
• ʻōpala i ʻeleʻele, hoʻoluhi, palu, a i ʻole loaʻa i ke koko a i ʻole nā ​​mucus
• ʻeha nui i ka ʻōpū
• nausea nui a luaʻi
• hoʻonui a hoʻēmi paha i ka makemake
• hoʻonui ka make wai
• ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū
• melemele o ka ʻili a me nā maka
• maʻalahi ke kahe ʻana a i ʻole ka palapū
• puʻuwai wikiwiki
• nā loli i ke kaupaona (loaʻa a pohō paha)
• poho lauoho
• hoʻonui sweating
• ʻano anuanu
• ka hohonu ʻana o ka leo a i ʻole ke kani ʻana
• pehu i mua o ka ʻāʻī (goiter)
• ʻūlū a nāwaliwali i nā wāwae, nā wāwae, nā lima a me nā lima
• ʻeha a kūpaʻa mau paha ke poʻo, ʻeha ka ʻeha
• nāwaliwali loa o ka mākala
• dizziness a i ʻole ʻālohilohi
• maule ana
• loli i ka nui a me ke kala o ka mimi
• ʻeha a i ʻole i ke ahi wela i ka wā e mimi ana
• koko i ka mimi
• nā hoʻololi i ka hihiʻo
• huikau

Hiki i ka injection injection Pembrolizumab ke kumu i nā hopena ʻē aʻe. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau i ka loaʻa ʻana o kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha aku kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka injection injection pembrolizumab. No kekahi mau kūlana, e kauoha kāu kauka i kahi hoʻokolohua hoʻokolohua ma mua o kou hoʻomaka ʻana i kāu lāʻau e ʻike inā hiki ke mālama ʻia i kou maʻi ʻaʻai me ka pembrolizumab.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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