Mea Kākau: Janice Evans
Lā O Ka Hana: 23 Iulai 2021
HōʻAno Hou I Ka Lā: 15 Nowemapa 2024
Anonim
PAR1 Inhibitors (Vorapaxar) Medmovie MOD/MOA Sample Only
Wikiō: PAR1 Inhibitors (Vorapaxar) Medmovie MOD/MOA Sample Only

Anter

Hoʻokumu paha ʻo Vorapaxar i ke kahe ʻana i ke kahe e hiki ke hoʻoweliweli i ke ola a hiki i ka make. E haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa i kahi maʻi kīkaha a i ʻole ʻāwī liʻiliʻi; kahe ana ka lolo i ka lolo; kekahi ʻano o ke koko a me nā maʻi koko; a i ʻole he ulcer ʻōpū. E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka vorapaxar. E haʻi aku i kāu kauka inā loaʻa iā ʻoe i kēia manawa kekahi ʻano o ke kahe ʻana o ke kahe e like me ke kahe ʻana i ke poʻo, ka ʻōpū, a me nā ʻōpū. inā he ʻoki hou kāu i hōʻeha ʻia a i ʻole ʻeha paha; a i ʻole he maʻi puʻuwai a ate paha. E haʻi i kāu kauka a me ka kauka inā ʻoe e lawe ana i ka anagrelide (Agrylin); nā lāʻau anti-inflammatory nonsteroidal (NSAIDs) e like me ibuprofen (Advil, Motrin, nā mea ʻē aʻe), indomethacin (Indocin, Tivorbex), ketoprofen, a me naproxen (Aleve, Anaprox, a me nā mea ʻē aʻe) i lawe mau ʻia; dabigatran (Pradaxa); dalteparin (Fragmin); enoxaparin (Lovenox); fondaparinux (Arixtra); heparin; rivaroxaban (Xarelto); nā mea hoʻoliʻiliʻi hou i nā serotonin reuptake (SSRI) e like me citalopram (Celexa), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil), a me sertraline (Zoloft); a me nā serotonin a me nā norepinephrine reuptake inhibitors (SNRI) e like me duloxetine (Cymbalta), desvenlafaxine (Khedezla, Pristiq), milnacipran (Fetzima, Savella), a me venlafaxine (Effexor); a me warfarin (Coumadin, Jantoven). Inā ʻoe e ʻike i kekahi o nā ʻōuli ma hope o kāu mālama ʻana a ma ka liʻiliʻi he 4 mau pule ma hope o kou hōʻoki ʻana i ka lawe ʻana i ka lāʻau, e kelepona koke i kāu kauka: kahe ʻana i ke koko i manaʻo ʻole ʻia, koʻikoʻi, a i ʻole hiki ʻole iā ʻoe ke kaohi; mimi, ʻulaʻula, a ʻeleʻele mimi paha; luaʻi i ke koko a i ʻole mea e like me ke kahua kope; ʻulaʻula a hoʻolōʻihi paha i nā noho ʻeleʻele; ke kuʻi nei i ke koko a i ʻole ke koko; ihu ihu; ʻeha poʻo; ʻūpā; a nāwaliwali paha.


E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka pepa ʻikepili a ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me vorapaxar a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka lawe ʻana i ka vorapaxar.

Hoʻohana pū ʻia ʻo Vorapaxar me nā lāʻau ʻē aʻe, e like me aspirin a me clopidogrel (Plavix), e hoʻoliʻiliʻi i ka pilikia o ka puʻuwai koʻikoʻi a i ʻole ke ola paha e like me ka hōʻeha puʻuwai a me ka hahau ʻana i ka poʻe i loaʻa i ka puʻuwai puʻuwai a i ʻole nā ​​pilikia. me ke kahe o ke koko i ko lākou mau wāwae. Aia ʻo Vorapaxar i loko o ka papa o nā lāʻau i kapa ʻia nā proteant-1 (PAR-1) protease-activated. Hana ia ma ka pale ʻana i nā platelet (kahi ʻano o ke kele koko) mai ka hōʻiliʻili ʻana a me ke kūkulu ʻana i nā clots e hiki ai ke hōʻeha i ka puʻuwai a i ʻole ka hahau.


Hele mai ʻo Vorapaxar ma ke ʻano he papa e lawe ma ka waha. Lawe pinepine ʻia me ka ʻai ʻole a ʻai ʻole hoʻokahi manawa i ka lā. E lawe i ka vorapaxar ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe pololei i ka vorapaxar. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E hoʻohaʻahaʻa wale ʻo Vorapaxar i kou makaʻi i ka puʻuwai puʻuwai a i ʻole ka hahau ke hoʻomau ʻoe i ka lawe ʻana i ka lāʻau. Mai hōʻoki i ka lawe ʻana i ka vorapaxar me ke kamaʻilio ʻole ʻana me kāu kauka.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka vorapaxar,

  • e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka vorapaxar, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa vorapaxar. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, a me nā mea hoʻopihaʻai pono ʻole āu e lawe nei a hoʻolālā paha e lawe. E hoʻomaopopo pono i nā lāʻau i helu ʻia i ka ʻĀINA WAIWAI nui a me kekahi o kēia mau mea: kekahi antifungals e like me itraconazole (Sporanox, Onmel), ketoconazole (Nizoral), a me posaconazole (Noxafil); boceprevir (Victrelis); carbamazepine (Carbatrol, Tegretol); clarithromycin (Biaxin, i PrevPac); konivaptan (Vaprisol); kekahi mau lāʻau no ka maʻi pale maʻi (HIV) e like me indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, ma Kaletra), a me saquinavir (Invirase); nefazodone; phenytoin (Dilantin, Phenytek); rifampin (Rifadin, Rimactane); telaprevir (Incivek); a me telithromycin (Ketek); Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
  • e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St. Johns.
  • e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa i kekahi ʻano olakino ʻoi aku i kēlā mau mea i helu ʻia i ka ʻĀINA WAIWAI.
  • e haʻi i kāu kauka inā hāpai ʻoe, hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana i ka vorapaxar, e kāhea i kāu kauka.
  • inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o ka niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i ka vorapaxar.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.


E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Vorapaxar i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • luhi
  • nāwaliwali
  • ʻili mae
  • ʻoluʻolu nā lima a me nā wāwae

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o nā ʻōuli i helu ʻia ma ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hoʻokumu paha ʻo Vorapaxar i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua. Mai wehe i ka desiccant (maloʻo maloʻo) mai ka ʻōmole, inā i hāʻawi ʻia kekahi.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Mālama i nā manawa āpau me kāu kauka.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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