ʻO Simeprevir

Anter

• Ma mua o ka lawe ʻana i ka simeprevir,
• Hoʻokumu paha ʻo Simeprevir i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i nā ʻARlelo AOAO IMPORTANT a me nā WAIWAI HOU, e kāhea koke aku i kāu kauka a i ʻole e kiʻi i nā lāʻau lapaʻau pilikia.

ʻAʻole loaʻa hou ʻo Simeprevir ma ʻAmelika Hui Pū ʻIa. Inā ʻoe e lawe nei i ka simeprevir, pono ʻoe e kāhea i kāu kauka e kūkākūkā i ka hoʻololi ʻana i kahi lāʻau ʻē aʻe.

Ua hele a maʻi paha ʻoe i ka maʻi hepatitis B (kahi maʻi i hoʻopili ʻia i ke akepaʻa a e hōʻeha paha i ka ate) akā ʻaʻohe o nā ʻōuli o ka maʻi. I kēia hihia, hiki i ka lawe ʻana i ka simeprevir ke hoʻonui i ka makaʻu e lilo i kou maʻi a ʻoi aku paha ka weliweli a ke hoʻomohala nei ʻoe i nā ʻōuli. E haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa i ka maʻi hepitis B hepatitis. E kauoha aku kāu kauka i kahi hoʻokolohua koko e ʻike inā loaʻa a loaʻa paha iā ʻoe i ka maʻi hepitis B. E nānā pū kāu kauka iā ʻoe no nā hōʻailona o ka maʻi hepatitis B i ka manawa a no kekahi mau mahina ma hope o kāu lapaʻau. Inā pono, hiki i kāu kauka ke hāʻawi iā ʻoe i lāʻau e mālama ai i kēia maʻi ma mua a i kou wā o ka mālama ʻana me simeprevir. Inā ʻoe e ʻike i kekahi o nā ʻōuli ma hope a i ʻole a ma hope paha o kāu lapaʻau ʻana, e kāhea koke aku i kāu kauka: luhi nui, melemele o ka ʻili a i ʻole nā ​​maka, lilo i ka makemake ʻole, nausea a i ʻole ka luaʻi, nā pale pale, ʻeha o ka ʻōpū, a me ka mimi ʻeleʻele.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha paha kāu kauka i kekahi mau hoʻokolohua ma mua, i ka wā, a ma hope o kāu mālama ʻana e nānā i ka pane o kou kino iā simeprevir.

E kamaʻilio me kāu kauka e pili ana i ka makaʻu (s) o ka lawe ʻana iā simeprevir.

Hoʻohana ʻia ʻo Simeprevir me ribavirin (Copegus, Rebetol) a me peginterferon alfa (Pegasys) e mālama i ka maʻi hepa hepatitis C (kahi maʻi viral e hoʻomau nei e hōʻino ai i ke ake). Aia ʻo Simeprevir i ka papa o nā lāʻau i kapa ʻia nā protease inhibitors. Hana ia ma ka hoʻemi ʻana i ka nui o ka maʻi hepitis C (HCV) i ke kino. ʻAʻole hiki iā Simeprevir ke pale i ka hoʻolaha ʻana o ka maʻi hepatitis C i kekahi poʻe ʻē aʻe.

Hele mai ʻo Simeprevir ma ke ʻano he capsule e lawe ma ka waha. Lawe mau ʻia me ka meaʻai hoʻokahi i ka lā. E lawe i ka simeprevir ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe pololei i ka simeprevir. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā capsule holoʻokoʻa; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou.

E lawe ʻoe i ka simeprevir me peginterferon alfa a me ribavirin no 12 mau pule. A laila e hoʻōki ʻoe i ka lawe ʻana i ka simeprevir a e lawe ʻoe i ka peginterferon a me ka ribavirin no 12 a 36 mau pule hou aʻe. ʻO ka lōʻihi o kāu lapaʻau e pili ana inā ua loaʻa iā ʻoe ka lāʻau ma mua no ka maʻi hepatitis C, pehea ʻoe i pane ai i ka mālama mua ʻana, pehea ʻoe e pane ai i nā lāʻau, a inā paha ʻoe e ʻike i nā hopena ʻino. E hoʻomau i ka lawe ʻana i ka simeprevir, peginterferon alfa, a me ka ribavirin ke lōʻihi ke kuhikuhi ʻia e kāu kauka. Mai hōʻoki i ka lawe ʻana i kekahi o kēia mau lāʻau me ke kamaʻilio ʻole ʻana me kāu kauka inā ʻoe ke olakino maikaʻi nei.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka simeprevir,

• e haʻi aku i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka simeprevir, nā lāʻau sulfa, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o nā capsule simeprevir. E noi i kāu kauka lāʻau a nānā paha i ka ʻike hoʻomanawanui o ka mea hana no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E ʻōlelo pono i kekahi o kēia mau mea: kekahi mau lāʻau antifungal e like me fluconazole (Diflucan), itraconazole (Onmel, Sporanox), ketoconazole, posaconazole (Noxafil), a i ʻole voriconazole (Vfend); nā poloka kalipuna e like me amlodipine (Norvasc), diltiazem (Cardizem, Dilacor XR, Tiazac), felodipine, nicardipine (Cardene), nifedipine (Adalat, Procardia), nisoldipine (Sular), a i ʻole verapamil (Calan, Verelan, kekahi) kekahi mau lāʻau no ke kolesterol kiʻekiʻe e like me atorvastatin (Lipitor, i Caduet), lovastatin (Altoprev), pitavastatin (Livalo), pravastatin (Pravachol), rosuvastatin (Crestor), a i ʻole simvastatin (Flolipid, Zocor, i Vytorin); cisapride (Propulsid) (ʻaʻole loaʻa ma ka U.S.); clarithromycin (Biaxin, i Prevpac); nā lāʻau i loaʻa i ka cobicistat (Stribild); erythromycin (EES, Eryc, Ery-tab, nā mea ʻē aʻe), kekahi mau lāʻau no ka HIV e like me atazanavir (Reyataz), darunavir (Prezista), delavirdine (Rescriptor), efavirenz (Sustiva), etravirine (Intelence), fosamprenavir (Lexiva), indinavir (Crixivan), lopinavir (Kaletra), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir), saquinavir (Invirase), a i ʻole tipranavir (Aptivus); kekahi mau lāʻau no ke kuʻi puʻuwai ʻole e like me amiodarone (Nexterone, Pacerone), disopyramide (Norpace), flecainide (Tambocor), mexiletine, propafenone (Rythmol SR), a i ʻole quinidine (i Nuedexta); cyclosporine (Gengraf, Neoral, Sandimmune); dexamethasone; digoxin (Lanoxin); ledipasvir (Harvoni); lawe ʻia ka midazolam e ka waha; rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, ma Rifamate, ma Rifater); rifapentine (Priftin); kekahi mau lāʻau no ka hopu ʻana e like me carbamazepine (Epitol, Equetro, Tegretol), oxcarbazepine (Trileptal), phenobarbital, a i ʻole phenytoin (Dilantin, Phenytek); sildenafil (ʻo ka inoa Revatio wale nō i hoʻohana ʻia no ka maʻi puʻupuʻu); sirolimus (Rapamune); tacrolimus (Prograf); tadalafil (ʻo ka brand Adcirca wale nō i hoʻohana ʻia no ka maʻi puʻupuʻu); telithromycin (Ketek); triazolam (Halcion) i lawe ʻia e ka waha; vardenafil (Levitra, Staxyn), a i ʻole warfarin (Coumadin, Jantoven). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me ka simeprevir, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka i nā huahana mea kanu āu e lawe nei, keu hoʻi i ka kaola o ka waiū a i ʻole ka wort o St. ʻAʻole pono ʻoe e lawe i ka lāʻau o ka waiū a i ʻole wort ʻo St. John i kou wā e mālama ai me simeprevir.
• e haʻi aku i kāu kauka inā ua loaʻa ʻoe i kahi hoʻoliʻiliʻi ate, inā ke loaʻa nei iā ʻoe ka phototherapy, inā he moʻokūʻauhau ʻAsia Hikina ʻoe, a inā he ʻano maʻi maʻi akepē ʻoe a i ʻole loaʻa kekahi ʻano maʻi maʻi ʻē aʻe ma mua o ka hepatitis C.
• e haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a i ʻole hiki paha ke hāpai. Inā he kāne ʻoe, e haʻi i kāu kauka inā hāpai kāu hoa, hoʻolālā e hāpai, a i ʻole hiki paha i hāpai. Pono e lawe ʻia ʻo Simeprevir me ka ribavirin i hiki ke hōʻeha nui i ka fetus. Pono ʻoe e hoʻohana i ʻelua mau ʻano hana o ka kaohi hānau e pale ai i ka hāpai ʻana i loko ou a i ʻole kāu hoapili i ka wā o ka mālama ʻana me kēia mau lāʻau a no 6 mau mahina ma hope o kāu lapaʻau. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana āu e hoʻohana ai; hormonal contraceptives (pills kaohi hānau, pāʻina, implants, apo, a i ʻole nā ​​injection) ʻaʻole holo pono paha i nā wahine e lawe nei i kēia mau lāʻau. Pono ʻoe a i ʻole kāu pakanā e hoʻāʻo no ka hāpai keiki ma mua o ka mālama ʻana, i kēlā me kēia mahina i kāu mālama ʻana, a no 6 mau mahina ma hope o kāu lapaʻau. Inā hāpai ʻoe a ʻo kāu hoa paha i ka lawe ʻana i kēia mau lāʻau, e kelepona koke i kāu kauka.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū.
• hoʻolālā e hōʻalo i ka pono ʻole a hoʻolōʻihi ʻia paha i ka lā a komo i nā lole pale, nā aniani aniani, ka pāpale, a me nā pale umauma i kou wā e mālama ai me simeprevir. E hōʻalo hoʻi i ka hoʻohana ʻana o nā moena ʻili, nā sunlamp, a i ʻole nā ​​ʻano hoʻomālamalama māmā i kāu wā e mālama ai. Hoʻomaopopo paha ʻo Simeprevir i kou ʻili i ka lā o ka lā. Kāhea koke aku i kāu kauka inā ʻike ʻoe i kahi lā nui o ka lā a i ʻole ke kuni ʻana, ʻulaʻula, pehu, palapū i kou ʻili, a i ʻole nā ​​maka ʻulaʻula a mumule paha.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala me ka ʻai ke hoʻomanaʻo ʻoe iā ia. Eia naʻe, inā he emi ia ma mua o 12 mau hola ma mua o ka manawa i hoʻonohonoho ʻia no kāu mahele aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Simeprevir i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• ʻūlili
• nausea
• ʻeha mākala

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i nā ʻARlelo AOAO IMPORTANT a me nā WAIWAI HOU, e kāhea koke aku i kāu kauka a i ʻole e kiʻi i nā lāʻau lapaʻau pilikia.

• paʻakikī i ka hanu ʻana
• hūwī
• ʻeha o ka waha a i ʻole ulcer
• ʻulaʻula a pehu paha nā maka ("maka ʻākala")

Hoʻokumu paha ʻo Simeprevir i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a mamao aku mai ka mālamalama, ka wela a me ka momona o ka wela (ʻaʻole i loko o ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Olopa^®