Mea Kākau: William Ramirez
Lā O Ka Hana: 24 Kepakemapa 2021
HōʻAno Hou I Ka Lā: 13 Nowemapa 2024
Anonim
ʻO Cabozantinib (ka maʻi ʻaʻai thyroid) - Kino PaʻA
ʻO Cabozantinib (ka maʻi ʻaʻai thyroid) - Kino PaʻA

Anter

Hoʻohana ʻia ʻo Cabozantinib (Cometriq) e mālama i kekahi ʻano o ka maʻi ʻaʻai thyroid e ʻino ana a pāhola aʻe i nā ʻāpana ʻē aʻe o ke kino. Aia ʻo Cabozantinib (Cometriq) i kahi papa o nā lāʻau i kapa ʻia nā mea kāohi lāʻau ʻo tyrosine kinase. Hana ia ma ke kāpae ʻana i ka hana o kahi protein pono ʻole e hōʻailona ai i nā hunaola maʻi ʻaʻai e hoʻonui. Kōkua kēia i ka hoʻolohi a hoʻopau paha i ka hoʻolaha ʻana o nā hunaola maʻi ʻaʻai.

Loaʻa ʻo Cabozantinib ma ke ʻano he papaha (Cabometyx) e mālama ai i ka carcinoma cell renal holomua (RCC; kahi ʻano maʻi ʻaʻai e hoʻomaka i nā hunaola o nā puʻupaʻa) a me ka maʻi hepela hepatocellular (HCC; kahi ʻano maʻi ʻaʻai ate) i kekahi mau maʻi i loaʻa ma mua ua mālama ʻia me kekahi lāʻau ʻē aʻe. Hāʻawi wale kēia monograf i ka ʻike e pili ana i nā cabozantinib capsules (Cometriq) no ka maʻi ʻaʻai thyroid. Inā ʻoe e hoʻohana ana i kēia lāʻau no ka holomua RCC a i ʻole HCC, e heluhelu i ka monograph i kapa ʻia cabozantinib (ate a me nā maʻi ʻaʻai kolo).

Hele mai ʻo Cabozantinib (Cometriq) ma ke ʻano he capsule e lawe ma ka waha. Lawe ʻia ia i hoʻokahi manawa i ka lā ma ka ʻōpū hakahaka, ma ka liʻiliʻi he 1 hola ma mua a me 2 mau hola ma hope o ka ʻai ʻana. Lawe iā cabozantinib (Cometriq) ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono iā cabozantinib (Cometriq) e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.


E ale i nā capsule a pau me ke kīʻaha piha (8 auneke, 240 mL) o ka wai. Mai wehe iā lākou.

Hiki i kāu kauka ke hōʻemi i kāu lāʻau o cabozantinib (Cometriq) a i ʻole kūmau manawa a kūloko paha i kāu lāʻau inā ʻike ʻoe i nā hopena ʻino. E kamaʻilio pono i kāu kauka e pili ana i kou ʻano e mālama ai me ka cabozantinib (Cometriq).

Aia ka lōʻihi o kāu mālama ʻana i ka maikaʻi o kāu pane ʻana i ka lāʻau a me nā hopena āu e ʻike ai. E hoʻomau i ka lawe ʻana iā cabozantinib (Cometriq) ʻoiai inā ʻoluʻolu ʻoe. Mai hōʻoki i ka lawe ʻana i cabozantinib (Cometriq) me ke kamaʻilio ʻole ʻana me kāu kauka.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i cabozantinib (Cometriq),

  • e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka cabozantinib (Cabometyx, Cometriq), nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o ka cabozantinib capsules. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, a me nā mea hoʻopihaʻaiʻai āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: adefovir (Hepsera); nā antifungals e like me itraconazole (Sporanox), ketoconazole, a me voriconazole (Vfend); clarithromycin (Biaxin, i Prevpac); dexamethasone; furosemide (Lasix); kekahi mau lāʻau no ka HIV a me ka AIDS e like me abacavir (Ziagen), atazanavir (Reyataz), cidofovir, indinavir (Crixivan), lamivudine (Epivir, i Combivir); nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, ma Kaletra), saquinavir (Invirase), a me tenofovir (Viread); kekahi mau lāʻau no ka hopu ʻana e like me ka carbamazepine (Equetro, Tegretol, Teril), phenobarbital, a me phenytoin (Dilantin, Phenytek); nefazodone; probenecid (Probalan), rifabutin (Mycobutin); rifampin (Rifactin, Rifadin, ma Rifamate, ma Rifater); rifapentine (Priftin); telithromycin (Ketek); a me warfarin (Coumadin, Jantoven). Hiki paha i nā lāʻau ʻē aʻe ke launa pū me cabozantinib (Cometriq), no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a e nānā pono paha iā ʻoe no nā hopena ʻaoʻao.
  • e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
  • e haʻi i kāu kauka inā loaʻa koke ʻoe i kahi kahe keu a koʻikoʻi ʻole paha e like me ke kahe ʻana o ke koko, ka luaʻi ʻana i ke koko, a i ʻole nā ​​kūleʻa koko a ʻeleʻele paha. E haʻi aku i kāu kauka inā loaʻa iā ʻoe kahi ʻeha hāmama a hoʻōla paha, a inā i loaʻa iā ʻoe a i ʻole loaʻa i ke koko kiʻekiʻe a i ʻole nā ​​maʻi ate.
  • e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. Pono ʻoe i kahi hōʻoia hāpai ma mua o kou hoʻomaka ʻana i ka lāʻau me cabozantinib. ʻAʻole ʻoe e hāpai i ka wā o kāu mālama ʻana me cabozantinib a no 4 mau mahina ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana hānau hiki iā ʻoe ke hoʻohana i kāu wā o kāu mālama ʻana. Inā hāpai ʻoe i kou lawe ʻana iā cabozantinib (Cometriq), e kāhea koke i kāu kauka. Hiki paha iā Cabozantinib ke hōʻeha i ka fetus.
  • e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. E haʻi paha kāu kauka iā ʻoe ʻaʻole e hānai i ka waiū i kāu wā e mālama ai a no 4 mau mahina ma hope o kāu hopena hope loa.
  • pono ʻoe e ʻike i kēia lāʻau i hoʻemi ai i ka momona i nā kāne a me nā wahine. E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka lawe ʻana i cabozantinib (Cometriq).
  • inā ke ʻoki ʻia ʻoe, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i cabozantinib (Cometriq). E haʻi paha kāu kauka iā ʻoe e haʻalele i ka lawe ʻana i ka cabozantinib (Cometriq) ma ka liʻiliʻi he 21 mau lā ma mua o kou ʻoki ʻana a e haʻi wau iā ʻoe i ka wā e hoʻomaka ai ʻoe e lawe i ka lāʻau ma hope o kāu ʻoki ʻana.
  • pono ʻoe e ʻike i ka cabozantinib (Cometriq) e hoʻopilikia ai i kou mau ā. Pono kahi kauka niho e nānā i kou mau niho ma mua o ka hoʻomaka ʻana e lawe i ka cabozantinib a maʻa mau i kāu wā e lapaʻau ai. E nānā pono e palaki i kou mau niho a hoʻomaʻemaʻe i kou waha pono ʻoiai ʻoe e lawe nei iā cabozantinib (Cometriq). E kamaʻilio me kāu kauka ma mua o ka loaʻa ʻana o nā lāʻau lapaʻau iā ʻoe e lawe nei i kēia lāʻau. E haʻi paha kāu kauka iā ʻoe e hōʻoki i ka lawe ʻana i ka cabozantinib ma ka liʻiliʻi he 21 mau lā ma mua o ke kauka niho.
  • pono ʻoe e ʻike e hoʻonui paha kou kahe koko i kou wā e mālama ai me cabozantinib (Cometriq). E nānā paha kāu kauka i kou kaomi koko i kou wā e lapaʻau ai.

Mai inu i ka wai huaʻikuʻu a ʻai paha i ka huaʻulu a i ʻole nā ​​meaʻai a i ʻole nā ​​mea hoʻopihapiha i loaʻa ka huaʻulu a i ʻole ka wai momona i ka wā e lawe nei ʻoe i kēia lāʻau.


E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā he emi ia ma mua o 12 mau hola a hiki i kāu kau palena hope e hoʻolālā ʻia, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

ʻO Cabozantinib (Cometriq) paha ke kumu o nā hopena. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • kōpaʻa
  • hemorrhoids
  • nausea
  • ka luaʻi
  • puʻuwai puʻuwai
  • hoʻololi i ka hiki ke ʻono i ka meaʻai
  • paʻakikī i ka ale ʻana
  • ʻulaʻula, pehu, ʻeha, a ʻeha paha i kou waha a i ʻole ka puʻu
  • nalo ʻai ʻole
  • Kaumaha emi
  • nāwaliwali a nāwaliwali paha
  • ʻeha ma nā ami
  • ʻeha ʻeha a ʻeha hoʻi
  • hopohopo
  • numbness, puhi ʻana, a i ʻole ke kani ʻana i nā lima, nā lima, nā wāwae, a me nā wāwae
  • ʻili maloʻo
  • mānoanoa patchy o ka ʻili
  • poho lauoho
  • ʻoi aku ka māmā o ka hina o ka lauoho a i ʻole hina
  • hoʻololi a leo paha ka leo

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

  • ke kuʻi nei i ke koko a i ʻole ke koko
  • luaʻi i nā mea koko a ʻano like paha me nā papa kope
  • kahe keu o ke kāne ma mua o ka maʻamau
  • ʻulaʻula a ʻeleʻele paha, noho aliʻi
  • kekahi kahe ʻole a kaumaha paha i ke kahe ʻana a i ʻole ka palapū
  • pāhoehoe
  • palapū a ʻeha paha i ka ʻōpū
  • pehu a ʻeha paha ma nā lima a me nā wāwae
  • pokole o ka hanu
  • ʻālohilohi a maʻule paha
  • ka houʻu ʻana
  • numbness a nāwaliwali paha o ka maka, ka lima, a me ka wāwae ma kekahi ʻaoʻao o kou kino
  • ʻūpā
  • pilikia paʻakikī me ke kaulike a me ka hoʻohui ʻana
  • gums pehu a ʻeha hoʻi
  • hikiwawe, ʻeha ke poʻo
  • ʻeha ka ʻāʻī
  • ʻeha ʻeha
  • ka hopu ʻana
  • pilikia pilikia hele wāwae
  • pilikia pilikia hikiwawe
  • huikau
  • paʻakikī paʻakikī e noʻonoʻo a ʻōlelo ʻana paha
  • hūwī
  • ʻulaʻula, ʻeha, ʻōhū, a i ʻole pāhuna ma nā palma a me nā kapuwaʻi
  • pilikia i ka ʻai ʻana a i ʻole ka inu ʻana ma muli o ka ʻeha o ka waha a i ʻole ka pāʻū a me ka luaʻi

ʻO Cabozantinib (Cometriq) paha ke kumu o nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.


Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki.http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

  • poho hoʻomanaʻo
  • huikau
  • Kaumaha emi

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino iā cabozantinib (Cometriq).

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

  • ʻO Cometriq®
Nānā Hou - 05/15/2020

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