Mea Kākau: Marcus Baldwin
Lā O Ka Hana: 16 Iune 2021
HōʻAno Hou I Ka Lā: 24 Ianuali 2025
Anonim
Apalutamide, darolutamide and enzalutamide for nonmetastatic castration-resistant prostate cancer.
Wikiō: Apalutamide, darolutamide and enzalutamide for nonmetastatic castration-resistant prostate cancer.

Anter

Hoʻohana ʻia ʻo Enzalutamide e mālama i ka maʻi ʻaʻai prostate i pāhola ʻia i nā wahi ʻē aʻe o ke kino i nā kāne a ua kōkua ʻia e kekahi mau lapaʻau a me nā hana ʻoki e hoʻemi i nā pae testosterone. Hoʻohana ʻia ia e mālama i ka maʻi ʻaʻai prostate i nā kāne i kōkua ʻole ʻia e kekahi ʻano olakino a me nā hana ʻoki e hoʻemi i nā pae testosterone. Aia ʻo Enzalutamide i loko o ka papa o nā lāʻau i kapa ʻia he androgen receptor inhibitors. Hana ia ma ke kāpae ʻana i nā hopena o androgen (kahi kāne reproductive hormone) e hoʻōki i ka ulu a hoʻolaha ʻana o nā hunaola maʻi ʻaʻai.

Hele mai ʻo Enzalutamide ma ke ʻano he papa a i ʻole he capsule e lawe ma ka waha. Lawe pinepine ʻia me ka ʻai ʻole a ʻai ʻole hoʻokahi manawa i ka lā. E lawe i ka enzalutamide ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pololei i ka enzalutamide e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa a i ʻole nā ​​capsule holoʻokoʻa; mai haki, nāhelehele, hoʻokaʻawale, hoʻoheheʻe, a wehe paha iā lākou.


E haʻi paha kāu kauka iā ʻoe e hōʻoki i ka lawe ʻana i ka enzalutamide no kekahi manawa pōkole a i ʻole e hoʻemi i kāu lāʻau inā ʻike ʻoe i nā hopena ʻino i kāu mālama ʻana. E mālama pono i kāu kauka e pili ana i kou ʻano i kou wā e mālama ai me ka enzalutamide.

Inā ua kau kauka i kahi lāʻau ʻē aʻe e like me degarelix (Firmagon), goserelin (Zoladex), histrelin (Supprelin LA, Vantas), leuprolide (Eligard, Lupron, ma Lupaneta Pack), a i ʻole triptorelin (Trelstar, Triptodur) e mālama i kāu maʻi ʻaʻai prostate , pono ʻoe e hoʻomau i ka loaʻa ʻana o kēia lāʻau i kou wā lapaʻau me ka enzalutamide.

E hoʻomau i ka lawe enzalutamide ʻoiai ʻoe e manaʻo maikaʻi. Mai hōʻoki i ka lawe ʻana i enzalutamide me ke kamaʻilio ʻole ʻana me kāu kauka.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i enzalutamide,

  • e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka enzalutamide, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa enzalutamide a i ʻole nā ​​capsule. E noi i kāu kauka lāʻau a nānā paha i ka ʻike a ka mea hana no ka mea maʻi no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, a me nā mea hoʻopihaʻaiʻai āu e lawe nei a hoʻolālā paha e lawe. E hoʻomaopopo pono e haʻi i kekahi o kēia mau mea: anticoagulants ('blood thinners') e like me warfarin (Coumadin, Jantoven), carbamazepine (Carbatrol, Equetro, Tegretol, a me nā mea ʻē aʻe), clopidogrel (Plavix), cyclosporine (Gengraf, Neoral, Sandimmune), dihydroergotamine (DHE 45, Migranal), ergotamine (ma Migergot, ma Cafergot), fentanyl (Actiq, Duragesic, Fentora, Subsys, a me nā mea ʻē aʻe), gemfibrozil (Lopid), itraconazole (Onmel, Sporanox), omeprazole (Prilosec), midazol , phenytoin (Dilantin, Phenytek), pimozide (Orap), quinidine (ma Nuedexta), rifabutin (Mycobutin, ma Talicia), rifampin (Rimactane, ma Rifamate, ma Rifater), rifapentine (Priftin), sirolimus (Rapamune), a me tacrolimus (Prograf). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Hiki paha i nā lāʻau ʻē aʻe ke launa pū me enzalutamide, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
  • e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
  • e haʻi i kāu kauka inā loaʻa ʻoe a i ʻole loaʻa paha i nā kuʻi, kahi ʻeha o ka lolo, kahi tumo lolo, kahi malformation o ka lolo (pili ʻole ma waena o nā aʻa a me nā uaua i loko o ka lolo e hana ma mua o ka hānau ʻana a hiki i ke kumu e kahe ai ka lolo i ka lolo), nā iwi haʻi, osteoporosis (kahi ʻano e lahilahi a nāwaliwali ai nā iwi a haki maʻalahi), diabetes, kiʻekiʻe nā pae kolesterol, ke koko kiʻekiʻe, nā maʻi puʻuwai, a i ʻole loaʻa i ka maʻi hahau a i ʻole ka ministroke.
  • pono ʻoe e ʻike i kēlā enzalutamide wale no ka hoʻohana i loko o nā kāne. ʻAʻole pono nā wahine e lawe i kēia lāʻau, keu hoʻi inā hāpai a hāpai paha lākou. ʻO nā wahine, ʻoi aku ka poʻe i hāpai a hāpai paha, ʻaʻole pono e hoʻopā i nā capsule enzalutamide. Inā lawe ʻia e nā wahine hāpai, hoʻopōʻino paha ka enzalutamide i ka fetus. Inā lawe ka wahine hāpai i enzalutamide, pono ʻo ia e kāhea koke i kāna kauka.
  • pono ʻoe e ʻike i kēia lāʻau i hoʻemi ai i ka momona i nā kāne. Eia naʻe, ʻaʻole pono ʻoe e kuhi i hiki ʻole i kāu wahine wahine ke hāpai. Inā hāpai kāu hoa, pono ʻoe e hoʻohana i kahi condom i kēlā me kēia manawa ke moe kolohe ʻoe i kāu wā e mālama ai me ka enzalutamide a no 3 mau mahina ma hope o kāu hopena hope loa. Inā hāpai ʻole kāu pakanā akā hiki i ka hāpai ʻana, pono ʻoe e hoʻohana i ka kaohi hānau kūpono ke loaʻa iā ʻoe ka moekolohe ma kāu mālama ʻana a no 3 mau mahina ma hope o kāu hopena hope loa.
  • inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o ka niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i enzalutamide.
  • pono ʻoe e ʻike ʻo ka enzalutamide ke kumu o ka hopu ʻana. Mai hoʻokele i kahi kaʻa a hana i nā mīkini a ʻike ʻoe i ka hopena o kēia lāʻau iā ʻoe.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.


E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā ʻaʻole ʻoe e hoʻomanaʻo a hiki i ka lā aʻe, kāpae i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i hoʻokahi ma mua o hoʻokahi mahele lāʻau i ka lā hoʻokahi a mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Enzalutamide i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • nāwaliwali
  • luhi
  • ʻeha pū
  • nāwaliwali o ka mākala a ʻoʻoleʻa
  • Kaumaha emi
  • nalo ʻai ʻole
  • ʻeha poʻo
  • ʻūpā
  • ka puhi ʻana, ka helu ʻana a i ʻole ka ʻūlū ʻana i nā lima, nā lima a me nā wāwae
  • hoʻemi i ke ʻano o ka pā a i ʻole hiki ke ʻike i ka naʻau
  • ʻālohilohi wela
  • paʻakikī e hiamoe a hiamoe paha
  • hopohopo
  • paʻakikī i ka hoʻomanaʻo ʻana, ka noʻonoʻo ʻana, a me ka nānā ʻana paha
  • pāhoehoe
  • kōpaʻa
  • ʻūlili
  • ʻili maloʻo
  • ihu ihu
  • urination pinepine
  • loli ka ʻono

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

  • ka hopu ʻana
  • ʻeha poʻo; huikau; a i ʻole hoʻololi i ka hihiʻo
  • ka pehu o ka maka, ke alelo, nā lehelehe, ka ʻāʻī, nā lima, nā wāwae, nā lima a me nā wāwae
  • fiva, uha, ʻeha puʻu, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
  • ʻeha ka umauma
  • pokole o ka hanu
  • ʻeha ma ke kua, nā mākala, a me / a i ʻole nā ​​wāwae
  • numbness a i ʻole ʻūlū ʻana i ka puʻu a i ʻole nā ​​wāwae
  • paʻakikī e kaohi i ka urination a i ʻole ka ʻōpū
  • paʻakikī i ka hanu ʻana
  • hāʻule ʻana
  • haki nā iwi a haki paha
  • hallucinating (ke ʻike nei i nā mea a i ʻole ka lohe ʻana i nā leo i ʻole)
  • hoʻonui ka umauma i nā kāne
  • mimi ʻulaʻula a ʻulaʻula paha

Hoʻokumu paha ʻo Enzalutamide i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.


Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

  • ka hopu ʻana

Mālama i nā manawa āpau me kāu kauka.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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