Ambrisentan

Anter

• Ma mua o ka lawe ʻana i ambrisentan,
• Hoʻokumu paha ʻo Ambrisentan i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.
• Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

Mai lawe i ka ambrisentan inā hāpai ʻoe a hoʻolālā paha e hāpai. Hoʻopilikia paha ʻo Ambrisentan i ka fetus. Inā he wahine ʻoe a hiki i ka hāpai ʻana, ʻaʻole pono ʻoe e hoʻomaka i ka ambrisentan a hiki i ka hōʻike ʻana o kahi hōʻike hāpai keiki ʻaʻole ʻoe hāpai. Pono ʻoe e hoʻohana i ʻelua mau ʻano hilinaʻi o ka kaohi hānau i ka wā o ka lapaʻau ʻana me kēia lāʻau a no 1 mau mahina ma hope o ka hoʻōki ʻana i ka lāʻau. Mai moe kolohe. E kamaʻilio me kāu kauka e pili ana i nā hana kaohi hānau e holo pono nāu. Kāhea koke i kāu kauka inā ʻike ʻoe i kahi wā menstrual a manaʻo paha ʻoe e hāpai ana ʻoiai ʻoe e lawe ana i ka ambrisentan.

Ma muli o ka makaʻu o ka hānau hānau, loaʻa ka ambrisentan i nā wahine wale nō ma o kahi papahana hoʻokaʻawale i kaupalena ʻia. Ua hoʻonohonoho ʻia kahi papahana i kapa ʻia ʻo Ambrisentan REMS (Risk Evaluation and Mitigation Strategy) e hōʻoia i ka loaʻa ʻana o ka wahine hoʻomanawanui i nā hoʻokolohua lab kūpono ma mua a ke loaʻa nei lākou i ka ambrisentan. Hiki i nā wahine ke kiʻi ambrisentan wale nō inā hoʻopaʻa inoa ʻia lākou me kēia papahana. Pono kāu kauka e kau inoa iā ʻoe i loko o kēia polokalamu. Hiki iā ʻoe ke loaʻa i ka lāʻau lapaʻau wale nō mai kahi kauka i komo i ka papahana. E nīnau i kāu kauka inā he nīnau paha kāu e pili ana i ke komo ʻana i ka papahana a pehea e loaʻa ai kāu lāʻau.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua i ka wā o kāu mālama ʻana me ka ambrisentan.

E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka palapala ʻike hoʻomanawanui o ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me ka ambrisentan a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu.Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

E kamaʻilio me kāu kauka e pili ana i ka makaʻu o ka lawe ʻana i ka ambrisentan.

Hoʻohana hoʻokahi ʻia ʻo Ambrisentan a i ʻole hui pū ʻia me tadalafil (Adcirca, Cialis) e mālama i ke kiʻekiʻe o ke aʻa (pulahary Hiki i ka Ambrisentan ke hoʻomaikaʻi i ka hiki ke hoʻoikaika kino a hoʻolōʻihi i ka hōʻino ʻana o nā hōʻailona i ka poʻe me PAH. Aia ʻo Ambrisentan i kahi papa o nā lāʻau i kapa ʻia he endagonhel receptor antagonists. Hana ia ma ka hoʻōki ʻana i ka hana o endothelin, kahi mea kūlohelohe e hoʻoliʻiliʻi ai nā kīʻaha koko a pale i ke kahe o ke koko maʻamau i ka poʻe i loaʻa iā PAH.

Hele mai ʻo Ambrisentan ma ke ʻano he papa e lawe ma ka waha. Lawe pinepine ʻia me ka ʻai ʻole a ʻai ʻole hoʻokahi manawa i ka lā. Lawe i ka ambrisentan ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe pololei i ka ambrisentan. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa holoʻokoʻa; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou.

E hoʻomaka paha kāu kauka iā ʻoe ma kahi haʻahaʻa o ka ambrisentan a hoʻonui iki i kāu lāʻau.

Hoʻopili ʻo Ambrisentan i nā ʻōuli o PAH akā ʻaʻole ia e hoʻōla iā ia. E hoʻomau i ka lawe ambrisentan ʻoiai ʻoe e manaʻo maikaʻi. Mai hōʻoki i ka lawe ʻana i ka ambrisentan me ke kamaʻilio ʻole ʻana me kāu kauka. Inā kū koke ʻoe i ka lawe ʻana i ka ambrisentan, e mānoanoa paha kou ʻano.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ambrisentan,

• e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka ambrisentan, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o nā papa ambrisentan. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E ʻōlelo pono inā lawe ʻoe i ka cyclosporine (Gengraf, Neoral, Sandimmune). Pono paha kāu kauka e hoʻololi i ka mahele lāʻau o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka inā loaʻa iā ʻoe ka idiopathic pulmonary fibrosis (scarring of the lungs with a unknown kumu). E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka ambrisentan.
• e haʻi i kāu kauka inā loaʻa a loaʻa paha iā ʻoe ka anemia (kahi haʻahaʻa ma mua o ka nui maʻamau o nā hunaola ʻulaʻula) a i ʻole nā ​​maʻi ate.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. Mai hānai i ka umauma inā ʻoe e lawe i ka ambrisentan.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Ambrisentan i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• ʻōhinu
• ʻili mae
• puʻuwai wikiwiki
• ʻeha poʻo

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• ka pehu o ka maka, ka ʻāʻī, ke alelo, nā lehelehe, nā maka, nā lima, nā wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
• hulahula
• pilikia i ka ale ʻana a me ka hanu ʻana
• hūwī
• loaʻa kaumaha kaumaha
• luhi loa
• nalo ʻai ʻole
• nele i ka ikaika
• nausea
• ka luaʻi
• ʻeha ma ka ʻākau o ka ʻōpū ma luna
• melemele o ka ʻili a me nā maka
• nā ʻōuli like flu
• ʻūlili
• mimi kala ʻeleʻele

ʻO kekahi mau kāne e lawe ana i kahi lāʻau e like me ka ambrisentan i hoʻomohala i kahi haʻahaʻa ma mua o ka helu sperm maʻamau (ka helu o nā kāne hānau kāne); kahi hopena e hoʻopili i ko lākou hiki i ka makuakāne i kahi keiki. E kamaʻilio me kāu kauka e pili ana i ka makaʻu o ka lawe ʻana i ka ambrisentan inā makemake ʻoe e loaʻa nā keiki i ka wā e hiki mai ana.

Hoʻokumu paha ʻo Ambrisentan i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

• ʻeha poʻo
• ʻōhinu
• ʻūpā
• nausea
• paheʻe ihu

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Letairis^®