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Hoʻohana ʻia ka hui ʻana o dextromethorphan a me quinidine e mālama ai i ka pseudobulbar (PBA; kahi ʻano o ka uē ʻana a i ʻole ka ʻakaʻaka ʻana i hiki ʻole ke kāohi ʻia) i ka poʻe me kekahi mau ʻano e like me ka amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease; ʻano kahi e make lohi ai nā aʻalolo e kāohi i ka neʻe ʻana o nā mākala, e hoʻoemi a nāwaliwali ai nā mākala) a i ʻole sclerosis maha (kahi maʻi kahi e holo pono ʻole ai nā ʻalolo a ʻike paha ka poʻe maʻi i ka nāwaliwali, numbness, nalo ʻana o ka hoʻohui ʻana o nā mākala a me nā pilikia me ka ʻike, ʻolelo, a me ka mālama ʻana i ka maʻi ʻaʻa. Aia ʻo Dextromethorphan i loko o ka papa o nā lāʻau i kapa ʻia ʻo nā ʻenemi kikowaena pūnaewele. ʻAʻole ʻike ʻia ke ala e hana ai i ka lolo e mālama iā PBA. Aia ʻo Quinidine i ka papa o nā lāʻau i kapa ʻia antiarrhythmics. Ke hoʻohui ʻia me dextromethorphan, hana ka quinidine ma ka hoʻonui ʻana i ka nui o dextromethorphan i loko o ke kino.

ʻO ka hui pū ʻana o dextromethorphan a me ka quinidine e hele mai ana ma ke ʻano he capsule e lawe ʻia e ka waha. Lawe ʻia ia me ka ʻai ʻole a ʻai ʻole hoʻokahi manawa i ka lā no 7 mau lā. Ma hope o 7 lā, lawe ʻia i kēlā me kēia 12 hola. Mai lawe i nā mea ʻoi aku ma mua o 2 mau lā i kahi manawa 24-hola. E ʻae e pili ma 12 mau hola ma waena o kēlā me kēia kau. Lawe iā dextromethorphan a me quinidine ma kahi o ka manawa like (s) i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe i ka hoʻohui o dextromethorphan a me ka quinidine pololei e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.


E nānā paha kāu kauka mai kēlā me kēia manawa e ʻike inā pono kēia lāʻau e kāohi i kāu mau ʻōuli. E hāhai pono i kēia mau ʻōkuhi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka dextromethorphan a me ka quinidine,

  • e haʻi i kāu kauka a me ka mea kauka lāʻau inā pili ʻoe i ka dextromethorphan, quinidine (Quinidex), quinine (Qualaquin), mefloquine (Lariam), nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hoʻohui i ka dextromethorphan a me ka quinidine capsules. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka inā lawe ʻoe mefloquine (Lariam), pimozide (Orap), quinine (Qualaquin) thioridazine, a i ʻole huahana ʻē aʻe i loaʻa ka quinidine (Quinidex). E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka dextromethorphan a me ka quinidine inā ʻoe e lawe i hoʻokahi a ʻoi paha o kēia mau lāʻau.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E hoʻomaopopo pono e ʻōlelo i kekahi o kēia mau mea: antidepressants me clomipramine (Anafranil), desipramine (Doxepin, Sinequan), fluoxetine (Prozac, Sarafem), nefazodone, a me paroxetine (Paxil, Pexeva); aprepitant (Emend); clarithromycin (Biaxin, Prevpac); ka hano a me nā lāʻau anuanu e pili ana ka dextromethorphan; cisapride; digoxin (Lanoxin, Digitek); erythromycin (E.E.S. E-Mycin, Erythrocin); fluconazole (Diflucan); itraconazole (Sporanox); ketoconazole (Nizoral); kekahi mau lāʻau no ka maʻi pale maʻi (HIV) e like me atazanavir (Reyataz), amprenavir (Agenerase), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, ma Kaletra), a me saquinavir (Invirase); nā lāʻau no ka puʻuwai puʻuwai ʻole e like me amiodarone (Cordarone), diltiazem (Cardizem, Cartia, Tiazac, a me nā mea ʻē aʻe), disopyramide (Norpace), dofetilide (Tikosyn), procainamide (Procanbid, Pronestyl), sotalol (Betapace), a me verapamil (Calan, Covera, Isoptin, Verelan, ma Tarka); nā lāʻau no ka ʻeha e like me codeine, hydrocodone (i ka Hydrogesic, Lorcet, Lortab, Vicodin, Zydone, a me nā mea ʻē aʻe), a me methadone; moxifloxacin (Avelox); sparfloxacin (Zagam); a me teliththromycin (Ketek). E haʻi aku i kāu kauka a kauka paha inā ʻoe e lawe nei i nā lāʻau aʻe a i ʻole ua oki ka lawe ʻana iā lākou i loko o nā pule ʻelua i hala aku nei: MAO nā mea hoʻopuka me isocarboxazid (Marplan), linezolid (Zyvox), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl ), a me tranylcypromine (Parnate). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Hiki paha i nā lāʻau ʻē aʻe ke launa pū me ka dextromethorphan a me ka quinidine, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
  • e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa i nā ʻano aʻe ke lawe ʻana i ka quinidine, ka quinine, a me ka mefloquine paha: e hoʻēmi i ka nui o nā hunaola o kou iwi iwi, lupus (kahi ʻano e hoʻouka ai ke kino i kāna mau pilikino ponoʻī e hōʻino ana a me ka pehu. ), a i ʻole hepatitis (ʻōhū o ke ake). E haʻi pū aku i kāu kauka inā loaʻa a i ʻole loaʻa paha ʻoe i nā puʻuwai puʻuwai abnormal a i ʻole ʻole ka puʻuwai. E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe iā takedextromethorphan a me quinidine.
  • e haʻi i kāu kauka inā loaʻa a loaʻa paha iā ʻoe ka myasthenia gravis (kahi maʻi o ka ʻōnaehana hopohopo e kumu ai i ka nāwaliwali o nā mākala), kahi moʻolelo o ka hoʻohana lāʻau ʻana i ke alanui a i ʻole hoʻohana hewa lāʻau lāʻau, ke koko kiʻekiʻe, kahi hahau, nā pae haʻahaʻa o ka potassium a me ka magnesium i kou koko, a puʻuwai paha, hakuʻala, a i ʻole maʻi ate.
  • e haʻi i kāu kauka inā hāpai ʻoe, hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana i ka hui o dextromethorphan a me quinidine, e kāhea i kāu kauka.
  • inā ke ʻoki ʻia ʻoe, e like me ke kaha ʻana o ka niho, e haʻi i ke kauka a i ʻole kauka niho paha ʻoe e lawe nei i ka dextromethorphan a me ka quinidine
  • pono ʻoe e ʻike ʻo ka dextromethorphan a me ka quinidine ka mea e hoʻoluhi ai iā ʻoe. He mea nui e makaʻala e pale i ka hāʻule i ka lawe ʻana i kēia lāʻau.
  • e nīnau i kāu kauka e pili ana i ka hoʻohana palekana o nā mea inu ʻona ʻoiai ʻoe e lawe nei i ka dextromethorphan a me ka quinidine. Hiki i ka waiʻona ke hana i nā hopena ʻino mai kēia lāʻau.

E kamaʻilio me kāu kauka e pili ana i ka ʻai ʻana i ka huaʻōlau a me ka inu ʻana i ka wai momona a ke lawe nei ʻoe i kēia lāʻau.


Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

Hōʻalo i ka lāʻau i hala a lawe i ka mahele hope aʻe i ka manawa maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala. E ʻae e ʻae i 12 mau hola ma waena o nā kau.

ʻO ka hui pū ʻana o dextromethorphan a me ka quinidine ke kumu i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • pāhoehoe
  • ka luaʻi
  • ʻenekini
  • ʻeha ka ʻōpū
  • ʻūhā
  • maka maloʻo a waha paha
  • nāwaliwali
  • ʻūpē mākala
  • ka pehu o nā lima, ka wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
  • pinepine, ʻeha, a i ʻole urination paʻakikī
  • mimi ʻohu a ʻala hoʻi

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:

  • fiva
  • kahe koko ʻole ʻana a palapū paha
  • ʻehaʻeha a ʻeha pū paha
  • hūwī
  • pehu o ka maka, puʻu, alelo, a lehelehe paha
  • pehu lymph node
  • hulahula
  • paʻakikī i ka hanu ʻana
  • ʻālohilohi
  • maule ana
  • kuʻi ka puʻuwai wikiwiki

ʻO ka hui pū ʻana o dextromethorphan a me ka quinidine ke kumu o nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.


Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā keiki a me nā holoholona. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Pākuʻi ʻia paha nā ʻōuli o ka overdose:

  • nausea
  • ka luaʻi
  • pāhoehoe
  • ʻūpā
  • ʻeha poʻo
  • kani i nā pepeiao
  • ʻike hihi ʻole a pālua paha
  • huikau
  • loli i ka puʻuwai puʻuwai
  • paʻakikī i ka hanu ʻana
  • nalowale o ka ʻike
  • ka hopu ʻana
  • nā hoʻololi i nā reflexes muscle
  • nalo o ke kūlike
  • pīhoihoi ʻole
  • noʻonoʻo ʻano ʻole

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha paha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka dextromethorphan a me ka quinidine. Hiki paha i kāu kauka ke kauoha i kahi electrocardiogram (ECG; hoʻāʻo e ana i ka hana uila i ka puʻuwai) ma mua a i kāu wā e lapaʻau ai.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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Nānā Hou - 11/15/2016

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