Telaprevir

Anter

• Ma mua o ka lawe ʻana i telaprevir,
• Hoʻokumu paha ʻo Telaprevir i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole kekahi o nā mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke aku i kāu kauka a i ʻole e kiʻi i nā lāʻau lapaʻau pilikia.
• Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

ʻAʻole loaʻa hou ʻo Telaprevir i ʻAmelika Hui Pū ʻIa ma hope o ʻOkakopa 16, 2014. Inā ʻoe e lawe nei i kēia manawa telaprevir, pono ʻoe e kāhea i kāu kauka e kūkākūkā e pili ana i ka hoʻololi ʻana i kahi lapaʻau ʻē aʻe.

Hoʻokumu paha ʻo Telaprevir i nā hopena ʻili koʻikoʻi a hoʻoweliweli paha i ke ola. Kāhea koke aku i kāu kauka a i ʻole e ʻimi i ka lāʻau olakino olakino inā ʻike ʻoe i kekahi o nā ʻōuli e hiki mai ana: ka ʻehu, ka pehu, a me nā ʻeha ma ka ʻili. ʻumeʻume; kuni; pehu o ka maka; ʻeha ma ka waha; a i ʻole nā ​​maka ʻulaʻula, pehu, ʻā, a haehae paha. E haʻi paha kāu kauka iā ʻoe e haʻalele i ka lawe ʻana i telaprevir (a ʻo kekahi mau lāʻau ʻē aʻe paha) inā he loli ka ʻili; mai hōʻoki i ka lawe ʻana i kāu lāʻau inā ʻaʻole i haʻi mai kāu kauka iā ʻoe e hana pēlā. Inā haʻi aku kāu kauka iā ʻoe e haʻalele i ka lawe ʻana i ka telaprevir ma muli o ka loli o ka ʻili, ʻaʻole pono ʻoe e lawe hou.

Hoʻohana ʻia ʻo Telaprevir me nā lāʻau ʻē aʻe ʻelua (ribavirin [Copegus, Rebetol] a me peginterferon alfa [Pegasys]) e mālama i ka maʻi hepitis C mau (kahi maʻi viral e hoʻomau nei e hōʻino ai i ke ake) i ka poʻe i mālama ʻole ʻia no kēia ʻano a i ʻole ʻaʻole hiki ke mālama maikaʻi ʻia ke ʻano me ribavirin a me peginterferon alfa wale nō. ʻO Telaprevir kahi papa o nā lāʻau i kapa ʻia nā protease inhibitors. Hana ia ma ka hoʻemi ʻana i ka nui o ka maʻi hepitis C (HCV) i ke kino. ʻAʻole hiki i Telaprevir ke pale i ka hoʻolaha ʻana o ka maʻi hepatitis C i kekahi poʻe ʻē aʻe.

Hele mai ʻo Telaprevir ma ke ʻano he papa e lawe ma ka waha. Lawe ʻia ia i ʻelua manawa i ka lā (i kēlā me kēia 10 a 14 mau hola). Pono ʻoe e ʻai i kahi pāʻina a i ʻole meaʻai māmā i loaʻa ma kahi o 20 mau momona o ka momona ma loko o 30 mau minuke ma mua o kou lawe telaprevir. Nā laʻana o nā meaʻai (nā mana maʻamau, ʻaʻole nā ​​momona a me nā huahana nonfat momona) i hiki ke lawe ʻia me telaprevir me: kahi ʻeke me ka waiūpaila, 1/2 kīʻaha kīʻaha, 3 punetēpī pīnī pīpī, 1 kīʻaha ʻaikalima, 2 auneke ʻAmelika a i ʻole cheddar tī, 2 auneke ʻuala potato, a i ʻole 1/2 kīʻaha ala ala kāwili. E noi i kāu kauka no kekahi mau laʻana ʻē aʻe o nā meaʻai i loaʻa i 20 mau momona o ka momona e hiki ai iā ʻoe ke ʻai ke lawe ʻoe i telaprevir. Mai lawe i ka telaprevir me ka ʻai ʻole. E lawe i ka telaprevir ma nā manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe pololei i telaprevir. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa holoʻokoʻa; mai hoʻokaʻawale, wāwahi, a nau hoʻi iā lākou. Inā ʻaʻole hiki iā ʻoe ke ale i nā papa āpau, e haʻi i kāu kauka.

E hoʻomau i ka lawe telaprevir inā ʻoe e ʻoluʻolu. Pono e lawe ʻia ʻo Telaprevir me ka peginterferon alfa a me ka ribavirin, maʻamau no 12 mau pule. Hoʻomau mau ʻia ʻo Peginterferon alfa a me ribavirin ma hope o ka pau ʻana o ka mālama ʻana me telaprevir. Mai hoʻoki i ka lawe ʻana i telaprevir, peginterferon alfa, a i ʻole ribavirin, ke ʻole i haʻi ʻia e kāu kauka.

E hāʻawi aku kāu kauka a mea kauka paha iā ʻoe i ka palapala ʻike hoʻomanawanui o ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me telaprevir a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i telaprevir,

• e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i telaprevir, ribavirin (Copegus, Rebetol), peginterferon alfa (Pegasys), nā lāʻau ʻē aʻe ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa telaprevir. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka inā e lawe nei ʻoe i kekahi o nā lāʻau aʻe a i ʻole nā ​​huahana lāʻau: alfuzosin (Uroxatral); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); cisapride (Propulsid) (ʻaʻole loaʻa hou i ka United States); nā lāʻau lapaʻau ergot e like me dihydroergotamine (D.H.E. 45, Migranal), ergotamine (Ergomar, in Cafergot, in Migergot), ergonovine, a me methylergonovine (Methergine); lovastatin (Altoprev, Mevacor, i Advicor); lawe ʻia ka midazolam e ka waha; phenobarbital, phenytoin (Dilantin, Phenytek); pimozide (Orap); rifampin (Rifadin, Rimactane, ma Rifamate, ma Rifater); sildenafil (ʻo ka inoa Revatio wale nō i hoʻohana ʻia no ka maʻi puʻupuʻu); simvastatin (Zocor, ma Simcor, ma Vytorin); St. John's wort; triazolam (Halcion); a me ka tadalafil (ʻo ka brand Adcirca wale nō i hoʻohana ʻia no ka maʻi maʻi māmā). E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i telaprevir inā ʻoe e lawe i hoʻokahi a ʻoi paha o kēia mau lāʻau.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, a me nā mea hoʻopihaʻai pono ʻole āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: alprazolam (Niravam, Xanax); anticoagulants ('blood thinners') e like me warfarin (Coumadin, Jantoven); nā lāʻau antifungal e like me itraconazole (Onmel, Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), a i ʻole voriconazole (Vfend); bosentan (Tracleer); budesonide (Pulmicort, Rhinocort, ma Symbicort); calcium blockers blockers e like me amlodipine (Norvasc, ma Amturnide, ma Tekamlo), diltiazem (Cardizem, Cartia XT, Dilacor, Diltzac, Dilt-CD, Tiazac, Taztia XT, a me nā mea ʻē aʻe), felodipine (Plendil), nicardipine (Cardene), nifedipine (Afeditab CR, Adalat, Procardia), nisoldipine (Sular), a me verapamil (Calan, Covera, Verelan, ma Tarka); kekahi mau lāʻau hoʻohaʻahaʻa kolesterol e like me atorvastatin (Lipitor, ma Caduet, ma Liptruzet), fluvastatin (Lescol), pitavastatin (Livalo), pravastatin (Pravachol), a me rosuvastatin (Crestor); clarithromycin (Biaxin, i Prevpac); colchisin (Colcrys, ma Col-probenecid); digoxin (Lanoxin); efavirenz (Sustiva, i Atripla); erythromycin (E.E.S., E-Mycin, a me nā mea ʻē aʻe); escitalopram (Lexapro); fentanyl (Abstral, Actiq, Duragesic, Fentora, Lazanda, Subsys); fluticasone (i Advair, Flonase, Flovent); hōʻaʻano pani hone (HRT); nā immunosuppressants e like me cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), a i ʻole tacrolimus (Prograf); nā lāʻau lapaʻau no ka hana erectile (ED) e like me sildenafil (Viagra), tadalafil (Cialis), a i ʻole vardenafil (Levitra, Staxyn); nā lāʻau no ke kuʻi puʻuwai ʻole e like me amiodarone (Cordarone, Pacerone), flecainide, lidocaine (Lidoderm, Lidopen, Xylocaine), propafenone (Rhythmol), a i ʻole quinidine; methadone (Dolophine, Methadose); ʻoki a midazolam; nā pale pale waha ('pills birth pills'); nā steroid ʻo waha e like me dexamethasone, methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol), a me prednisone (Rayos); repaglinide (Prandin, ma Prandimet); rifabutin (Mycobutin); ritonavir (Norvir, ma Kaletra) i hoʻohana ʻia me nā mea kūpina protease HIV ʻē aʻe e like me atazanavir (Reyataz), darunavir (Prezista), fosamprenavir (Lexiva), a me lopinavir (i Kaletra); salmeterol (Serevent, ma Advair); telithromycin (Ketek); tenofovir (Viread, ma Atripla, ma Stribild, ma Truvada); trazodone (Oleptro); a me zolpidem (Ambien, Edluar, Intermezzo, Zolpmist). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me telaprevir, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka inā loaʻa iā ʻoe kahi transplant organ. E haʻi aku i kāu kauka inā loaʻa a loaʻa paha iā ʻoe ka anemia (ʻaʻole lawa i nā hunaola ʻulaʻula i ke koko e halihali i ka oxygen i ke koena o ke kino), gout maʻi pale maʻi kanaka (HIV), nā pilikia me kāu ʻōnaehana pale maʻi, ka maʻi hepitis B (HBV) a i ʻole nā ​​maʻi ate ʻē aʻe ma mua o ka hepatitis C ..
• inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o nā niho, e haʻi i kāu kauka a i ʻole kauka niho paha e lawe nei ʻoe i telaprevir.
• e haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a i ʻole hiki paha ke hāpai. Inā he kāne ʻoe, e haʻi i kāu kauka inā hāpai kāu hoa, hoʻolālā e hāpai, a i ʻole hiki paha i hāpai. Pono e lawe ʻia ʻo Telaprevir me ribavirin, i hiki ke hōʻeha i ka fetus. Pono ʻoe e hoʻohana i ʻelua mau hana o ka kaohi hānau ʻana e pale ai i ka hāpai ʻana i loko ou a i ʻole kāu pakanā i kou wā e mālama ʻia ai me kēia mau lāʻau a no 6 mau mahina ma hope o kāu lapaʻau. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana āu e hoʻohana ai; hormonal contraceptives (birth control pills, patches, implants, ring, or injection) ʻaʻole holo pono paha i nā wahine e lawe nei i kēia mau lāʻau a hiki i 2 mau pule ma hope o ka lapaʻau. Pono ʻoe a me kāu pakanā e hoʻāʻo no ka hāpai keiki i kēlā me kēia mahina i kāu mālama ʻana a no 6 mau mahina ma hope o kāu lapaʻau. Inā hāpai ʻoe a ʻo kāu hoa paha i ka lawe ʻana i kēia mau lāʻau, e kelepona koke i kāu kauka.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū.

E akahele pono ʻoe e inu i ka wai i ka wā o kāu mālama ʻana me kēia lāʻau.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

Inā hoʻomanaʻo ʻoe i ka lāʻau i hala ma loko o 6 mau hola o ka manawa āu i hoʻonohonoho ʻia ai e lawe, lawe i ka lāʻau i hala me ka meaʻai māmā a i ʻole ka pāʻina (aia ma kahi o 20 mau momona o ka momona) koke. Eia nō naʻe, inā ʻoi aku ia ma mua o 6 mau hola mai kou lawe ʻana i ka lāʻau, haʻalele i ka lāʻau i hala ʻole a hoʻomau me kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Telaprevir i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• nausea
• ka luaʻi
• pāhoehoe
• hoʻololi i ka hiki ke ʻono
• ʻūlili
• hemorrhoids
• hōʻoluʻolu, puhi ʻana, a i ʻole nā ​​aniani a puni ka anus

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole kekahi o nā mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke aku i kāu kauka a i ʻole e kiʻi i nā lāʻau lapaʻau pilikia.

• ʻili mae
• ʻūpā
• pokole o ka hanu
• luhi
• nāwaliwali
• hoʻonui ka make wai
• mimi kala ʻeleʻele
• waha maloo
• hoʻemi i ke alapine urination a i ʻole ka nui
• paʻakikī i ka ʻai ʻana a i ʻole ka luaʻi nui a i ʻole ka diarrhea.

Hoʻokumu paha ʻo Telaprevir i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

• nausea
• pāhoehoe
• ka luaʻi
• ʻeha poʻo
• nalo ʻai ʻole
• hoʻololi i ka ʻono

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i telaprevir.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Incivek^®