ʻO Fingolimod

Anter

• Ma mua o ka lawe ʻana i ka fingolimod,
• Hoʻokumu paha ʻo Fingolimod i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:
• Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

Hoʻohana ʻia ʻo Fingolimod i mea e pale aku ai i nā hanana o nā ʻōuli a hoʻolohi i ka hōʻino ʻana o ke kīnā ʻole i nā mākua a me nā keiki he 10 mau makahiki a ʻoi paha o ka makahiki me nā hoʻi hou ʻana (papa o ka maʻi kahi e piʻi ai nā ʻōuli mai kēlā me kēia manawa) o ka nui sclerosis (MS; kahi maʻi kahi e hana pono ʻole ai nā aʻalolo a ʻike paha ka poʻe i ka nāwaliwali, numbness, nalo ʻana o ka coordination o nā mākala, a me nā pilikia me ka hihi, ka ʻōlelo, a me ka kaohi o ka maʻi ʻaʻa. Aia ʻo Fingolimod i loko o ka papa o nā lāʻau i kapa ʻia ʻo sphingosine l-phosphate receptor modulator. Hana ia ma ka hoʻemi ʻana i ka hana o nā hunaola ʻino e hiki ai ke hōʻino i nā nerve.

Hele mai ʻo Fingolimod ma ke ʻano he capsule e lawe ma ka waha. Lawe ʻia ia i hoʻokahi manawa i ka lā me ka ʻai ʻole. E lawe i ka fingolimod ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe pololei i ka fingolimod e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

Hiki i ka Fingolimod ke hoʻolohi i ka puʻuwai o ka puʻuwai i nā mākua a me nā keiki, keu hoʻi i nā hola he 6 ma hope o kou lawe ʻana i kāu lāʻau mua, a ma hope o ka mahele mua ke hoʻonui ʻia ka lāʻau i nā keiki. E loaʻa iā ʻoe kahi electrocardiogram (ECG; hōʻike e hoʻopaʻa i ka hana uila o ka puʻuwai) ma mua o kou lawe ʻana i kāu lāʻau mua a me 6 mau hola ma hope o kou lawe ʻana i ka lāʻau. E lawe ʻoe i kāu kau mua o ka fingolimod ma ke keʻena o kāu kauka a i ʻole kahi wahi olakino ʻē aʻe. Pono ʻoe e noho ma ke keʻena lapaʻau no 6 mau hola ma hope o kou lawe ʻana i ka lāʻau i hiki ke nānā ʻia. Pono ʻoe e noho ma ke keʻena olakino no ka lōʻihi ma mua o 6 mau hola a i ʻole ka pō inā loaʻa iā ʻoe kekahi mau ʻano a i ʻole lawe i kekahi mau lāʻau e hoʻonui i ka makaʻu e lohi ai kou puʻuwai a i ʻole inā lohi kou puʻuwai ma mua o ka mea i manaʻo ʻia a hoʻomau i ka lohi ma hope o ka 6 mua. mau hola. Pono paha ʻoe e noho ma kahi keʻena olakino ma kahi o 6 mau hola ma hope o kou lawe ʻana i kāu hopena ʻelua inā lohi nui kou puʻuwai ke lawe ʻoe i kāu kau mua. E haʻi i kāu kauka inā ʻike ʻoe i ka luhi, ka luhi, ka ʻeha o ka umauma, a i ʻole ke kuʻi puʻuwai a i ʻole wā maʻamau i kēlā me kēia manawa i kou wā e lapaʻau ai, keu hoʻi i loko o nā 24 mau hola ma hope o kou lawe ʻana i kāu kau mua.

Hiki i ka Fingolimod ke kōkua i ke kaohi i nā sclerosis he nui akā ʻaʻole ia e hoʻōla iā ia. Mai hōʻoki i ka lawe ʻana i ka fingolimod me ke kamaʻilio ʻole ʻana me kāu kauka. Inā ʻaʻole ʻoe e lawe i ka fingolimod no 1 lā a ʻoi aku paha i loko o nā pule he 2 mua o ka hoʻomaʻamaʻa ʻana, no 1 pule a ʻoi aku paha i ka pule ʻekolu a ʻehā o ka hoʻomaʻamaʻa ʻana a i ʻole 2 mau pule a ʻoi aku paha ma hope o ka malama mua o ka lapaʻau hoʻomaka ʻoe e lawe hou. Hiki paha iā ʻoe ke ʻike i ka puʻuwai lohi ke hoʻomaka ʻoe e lawe hou i ka fingolimod, no laila pono ʻoe e hoʻomaka hou i ka lāʻau i ke keʻena o kāu kauka.

E hāʻawi aku kāu kauka a mea kauka paha iā ʻoe i ka palapala ʻike hoʻomanawanui o ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me ka fingolimod a i kēlā me kēia manawa e hoʻopiha hou i kāu kuhikuhi. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka fingolimod,

• e haʻi aku i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka fingolimod, Inā loaʻa iā ʻoe kahi hopena maʻi kūpilikiʻi i ka fingolimod a i ʻole kekahi o nā mea hana i loko o nā capsules fingolimod (hū, hives, pehu o ka maka, maka, waha, ʻāʻī, alelo, lehelehe, nā lima, nā wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo), e ʻōlelo paha kāu kauka ʻaʻole e hoʻokau i ka manamana lima. Eia kekahi, e haʻi i kāu kauka inā he maʻi ʻoe i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hoʻohui i loko o nā capsule fingolimod. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka inā e lawe nei ʻoe i nā lāʻau no ka puʻuwai ʻole e like me amiodarone (Nexterone, Pacerone), disopyramide (Norpace), dofetilide (Tikosyn), dronedarone (Multaq), ibutilide (Corvert), procainamide, quinidine (i Nuedexta), a me sotalol (Betapace, Sorine, Sotylize). E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka fingolimod inā ʻoe e lawe i hoʻokahi a ʻoi paha o kēia mau lāʻau.
• e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻole ʻia, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe i kāu wā e mālama ai me ka manamana E kuhikuhi pono i kekahi o kēia mau mea: beta-blockers e like me atenolol (Tenormin, ma Tenoretic), carteolol, labetalol (Trandate), metoprolol (Lopressor, Toprol-XL, ma Dutoprol, ma Lopressor HCT), nadolol (Corgard, i Corzide), nebivolol (Bystolic, i Byvalson), propranolol (Inderal LA, Innopran XL), a me timolol; diltiazem (Cardizem, Cartia, Tiazac, nā mea ʻē aʻe); chlorpromazine; citalopram (Celexa); digoxin (Lanoxin); erythromycin (E.E.S., Ery-Tab, PCE, nā mea ʻē aʻe); haloperidol (Haldol); ketoconazole; nā lāʻau no nā pilikia puʻuwai; methadone (Dolophine, Methadose); a me ka verapamil (Calan, Verelan, ma Tarka).E haʻi aku iā ʻoe i ke kauka inā lawe ʻoe i kekahi o nā lāʻau aʻe, a i ʻole inā ua lawe ʻoe iā lākou i ka wā ma mua: ʻo corticosteroids e like me dexamethasone, methylprednisolone, a me prednisone; nā lāʻau no ka maʻi ʻaʻai; a me nā lāʻau e hoʻonāwaliwali ai ʻole kaohi ʻana i ka ʻōnaehana pale e like me mitoxantrone, natalizumab (Tysabri), a me teriflunomide (Aubagio), pono paha i kāu kauka e hoʻololi i nā kaukana o kāu mau lāʻau a e nānā pono iā ʻoe no nā hopena ʻaoʻao. Hiki paha i nā lāʻau ʻē aʻe ke launa pū me ka fingolimod, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole kekahi o kēia mau ʻano i loko o nā mahina ʻeono i hala iho nei: ka puʻuwai puʻuwai, angina (ʻeha o ka umauma), hahau a i ʻole hahau iki ʻana, a i ʻole nā ​​puʻuwai puʻuwai. E haʻi aku i kāu kauka inā lōʻihi kou QT syndrome (ke ʻano e hoʻonui ai i ka makaʻu o ka hoʻomohala ʻana i kahi puʻuwai kūpono ʻole e hiki ai i ka nāwaliwali a make koke paha) a i ʻole ka puʻuwai puʻuwai ʻole. E haʻi paha kāu kauka iā ʻoe mai lawe i ka fingolimod.
• e haʻi aku i kāu kauka inā ua maule ʻoe, ua ʻeha ka puʻuwai, hahau, a i ʻole pākuʻi liʻiliʻi, a inā he kuni kou a i ʻole nā ​​hōʻailona ʻino ʻē aʻe, inā loaʻa ʻoe i kahi maʻi e hele mai a hele ʻole a i ʻole hele aku, a inā ua loaʻa ʻoe a i ʻole ua loaʻa ka maʻi diabetes; papahō moe (ke ʻano e hoʻomaha iki ai i ka hanu ʻana i nā manawa he nui i ka pō) a i ʻole nā ​​pilikia hanu ʻē aʻe; ke koko kiʻekiʻe; uveitis (pehu o ka maka) a i ʻole nā ​​pilikia maka ʻē aʻe; he puʻuwai puʻuwai nā pae haʻahaʻa o ka potassium a me ka magnesium i kou koko; maʻi ʻaʻai o ka ʻili, a i ʻole ka maʻi puʻuwai a i ʻole ate. E haʻi aku i kāu kauka inā loaʻa iā ʻoe kahi lāʻau lapaʻau.
• e haʻi i kāu kauka inā hāpai ʻoe a hoʻolālā paha e hāpai, a i ʻole e hānai umauma ʻana. Pono ʻoe e hoʻohana i ka kaohi hānau e pale ai i ka hāpai ʻana i kāu wā lapaʻau a no 2 mau mahina ma hope o kāu hopena hope loa. Inā hāpai ʻoe i ka lawe ʻana i ka fingolimod a i ʻole ma waena o 2 mau mahina ma hope o kāu hopena hope loa, e kāhea i kāu kauka.
• ʻaʻohe o nā lāʻau lapaʻau i ka wā o kāu mālama ʻana me ka fingolimod a i ʻole no 2 mau mahina ma hope o kāu hopena hope loa me ke kamaʻilio ʻole ʻana me kāu kauka. E kamaʻilio me kāu kauka o kāu keiki e pili ana i nā lāʻau āpau e pono ai i kāu keiki e loaʻa ma mua o ka hoʻomaka ʻana i kāna hana me ka fingolimod.
• e haʻi i kāu kauka inā ʻaʻole i loaʻa i ka pox moa a ʻaʻole i loaʻa iā ʻoe ka lāʻau lapaʻau ʻo ka moa. Kauoha paha kāu kauka i kahi hoʻokolohua koko e ʻike inā ua ʻike ʻia ʻoe i ka moa moa. Pono ʻoe e loaʻa i ka lāʻau laʻau moa a laila kali i hoʻokahi mahina ma mua o ka hoʻomaka ʻana i kāu lāʻau me ka fingolimod.
• e hoʻolālā e hōʻalo i ka ʻike kūpono ʻole a hoʻolōʻihi ʻia paha i ka lā a me ke kukui UV (e like me nā keʻena tanning) a e komo i nā lole pale, nā aniani aniani, a me ka sunscreen. Hiki i ka Fingolimod ke hana i kou ʻili i maʻalahi i ka hopena weliweli o ka lā, a hoʻonui i kou makaʻu i ka ulu ʻana i ka maʻi ʻaʻai ʻili.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a kāhea i kāu kauka ma mua o kou lawe ʻana i ka lāʻau aʻe. Pono paha ʻoe e kiaʻi ʻia i kou hoʻomaka hou ʻana i kāu lāʻau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Fingolimod i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• nāwaliwali
• ʻeha kua
• ʻeha ma nā lima a me nā wāwae
• pāhoehoe
• abdominal eha
• nausea
• ʻeha poʻo a migraine paha
• poho lauoho

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:

• ʻūlū puʻuwai
• ʻeleʻele, hives, ʻili; pehu o ka maka, maka, waha, ʻāʻī, elelo a i ʻole lehelehe; a i ʻole paʻakikī i ka ale ʻana a me ka hanu ʻana
• ʻeha ka ʻāʻī, ʻehaʻeha o ke kino, ke kuni, ka haʻalulu, ka ʻūhā, a me nā hōʻailona ʻē aʻe o ka maʻi a i ka wā o ka mālama ʻana a no 2 mau mahina ma hope o kāu mālama
• ʻeha poʻo, ʻāʻī ʻoʻoleʻa, kuni, ʻike i ka mālamalama, nausea, a huikau paha i ka wā o ka mālama ʻana a no 2 mau mahina ma hope o kāu lapaʻau
• ʻeha, puhi, ʻāʻī, a i ʻole ʻūlū ʻana i ka ʻili, ʻike i ka hoʻopā, pehu, a i ʻole ka ʻūlū i ka wā o ka mālama
• ʻehaʻeha kūpikipiki nui, huikau, hoʻololi i ka hihiʻo, a i ʻole ka hopu ʻana
• blurriness, aka, a i ʻole kahi makapō i waenakonu o kāu ʻike; ʻike i ka mālamalama; kala ʻokoʻa i kāu hihiʻo a i ʻole nā ​​pilikia ʻike
• nā hoʻololi i kahi mole e kū nei; kahi ʻeleʻele hou i ka ʻili; nā ʻeha e hoʻōla ʻole ai; nā ulu ma kou ʻili e like me ka puʻupuʻu e hinuhinu, keʻokeʻo pearly, ʻili-ʻulaʻula, a ʻulaʻula, a i ʻole nā ​​hoʻololi ʻē aʻe i kou ʻili.
• nāwaliwali ma kekahi ʻaoʻao o ke kino a i ʻole nā ​​clumsiness o nā lima a mau wāwae paha e ʻino i ka holo ʻana o ka manawa. nā hoʻololi i kou noʻonoʻo, hoʻomanaʻo, a kaulike paha; huikau a ʻano pilikino paha; aiʻole ka nalowale o ka ikaika
• pōkole hou o ka hanu
• nausea, luaʻi, nalo o ka makemake ʻole, ʻeha o ka ʻōpū, melemele o ka ʻili a me nā maka, a i ʻole ka mimi ʻeleʻele

Hiki i ka Fingolimod ke hoʻonui i ka makaʻu o ka ulu ʻana i ka maʻi ʻaʻai a me ka lymphoma (ka maʻi ʻaʻai e hoʻomaka i nā hunaola e hakakā i ka maʻi). E kamaʻilio me kāu kauka e pili ana i ka makaʻu i ka lawe ʻana i kēia lāʻau.

Hiki ke piʻi aʻe kahi mahele o nā hōʻailona MS a me ka hōʻino ʻana o ke kīnā ʻole ma waena o 3 a 6 mau mahina ma hope o kou hoʻōki ʻana i ka lawe ʻana i ka manamana lima. E haʻi i kāu kauka inā hōʻeha kāu mau hōʻailona MS ma hope o ka kuʻu ʻana o ka fingolimod.

Hoʻokumu paha ʻo Fingolimod i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

• lohi a kuʻi ʻole paha ka puʻuwai puʻuwai

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha aku kāu kauka i kekahi mau hoʻokolohua lab, a me ka ʻili a me nā hoʻokolohua maka, a e nānā i kou kahe koko ma mua a i kou wā e hoʻomaʻamaʻa ai e palekana ʻo ʻoe ka hoʻomaka ʻana e lawe a hoʻomau i ka lawe ʻana i ka manamana lima.

Ma mua o ka loaʻa ʻana o kahi hoʻokolohua hoʻokolohua, e haʻi i kāu kauka a me nā limahana o ke keʻena hoʻokolohua āu e lawe nei i ka fingolimod.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Gilenya^®