Pākuʻi Blinatumomab

Anter

• Ma mua o ka loaʻa ʻana o ka inikina blinatumomab,
• Hoʻokumu paha ka pīhoihoi Blinatumomab i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i nā ʻARlelo AOAO PAHAʻOHE a i ʻole nā ​​kaʻina kūikawā, e kelepona koke i kāu kauka a i ʻole e kiʻi i nā lāʻau lapaʻau pilikia.
• Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

Blinatumomab injection pono e hāʻawi ʻia ma lalo o ka nānā ʻana a ke kauka me ka ʻike i ka hoʻohana ʻana i nā lāʻau chemotherapy.

Hiki i ke kīʻaha Blinatumomab ke kumu i kahi hopena koʻikoʻi weliweli e hiki ke hana ʻia i ka wā e hoʻokomo ʻia ai kēia lāʻau. E haʻi i kāu kauka inā ua loaʻa ʻoe i kahi hopena i ka blinatumomab a i ʻole nā ​​lāʻau ʻē aʻe. E loaʻa iā ʻoe kekahi mau lāʻau e kōkua ai i ka pale ʻana i kahi hopena maʻi ma mua o kou loaʻa ʻana i kēlā me kēia lāʻau o blinatumomab. Inā ʻoe e ʻike i kekahi o nā ʻōuli ma hope a i ʻole ma hope o ka loaʻa ʻana o ka blinatumomab, e haʻi koke aku i kāu kauka: ke kuni, ka luhi, nāwaliwali, ka palaho, ka maʻi poʻo, kahoʻi, ka luaʻi, ka haʻalulu, ka ʻehu, ka pehu ʻana o ka maka, ka hū ʻana, a i ʻole ka hanu paʻakikī. Inā loaʻa iā ʻoe kahi hopena koʻikoʻi, e hōʻoki ke kauka i kāu infusion a mālama i nā ʻōuli o ka hopena.

Hiki i ke kīpuna Blinatumomab ke kumu i nā hopena koʻikoʻi o ka ʻōnaehana kikowaena. E haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa paha i ka hopu ʻana, ka huikau, ka nalo ʻana o ke kaulike, a i ʻole ka pilikia e ʻōlelo. Inā ʻike ʻoe i kekahi o nā ʻōuli aʻe, e haʻi koke aku i kāu kauka: ka hopu ʻana, ka lulu ʻole ʻana o kahi ʻāpana o ke kino, ka paʻakikī ʻōlelo ʻana, ka ʻōlelo lōkō, ka nalowale ʻana o ka noʻonoʻo, ka paʻakikī o ka hiamoe ʻana a me ka hiamoe ʻana paha, ka ʻeha ke poʻo, ka huikau, a me ka nalo ʻole o ke kaulike .

E kamaʻilio me kāu kauka e pili ana i ka makaʻu (s) o ka hoʻohana ʻana i ka inikina blinatumomab.

Hoʻohana ʻia ʻo Blinatumomab i nā mākua a me nā keiki e mālama ai i kekahi ʻano o ka leukemia lymphocytic nui (ALL; kahi ʻano maʻi ʻaʻai o nā hunaola keʻokeʻo) ʻaʻole i ʻoi aku ka maikaʻi, a i hoʻi mai paha ma hope o ka lapaʻau ʻana me nā lāʻau ʻē aʻe. Hoʻohana pū ʻia ʻo Blinatumomab i nā mākua a me nā keiki e mālama i nā MEA āpau i ke kala ʻana (kahi hōʻemi a nalo ʻana paha o nā hōʻailona a me nā ʻōuli o ka maʻi ʻaʻai), akā koe kekahi mau hōʻike o ka maʻi ʻaʻai. Aia ʻo Blinatumomab i loko o ka papa o nā lāʻau i kapa ʻia he bispecific T-cell engager antibodies. Hana ia ma ka hoʻolohi a hoʻopaʻa ʻana i ka ulu ʻana o nā hunaola maʻi ʻaʻai i loko o kou kino.

Hele mai ʻo Blinatumomab ma ke ʻano he pauka e kāwili ʻia me ka wai e hoʻokomo lohi ʻia i loko o ke aniani (i loko o kahi aa) e ke kauka a kahu hānai paha i kahi haukapila a i ʻole kahi manawa olakino ma ka home Hāʻawi mau ʻia kēia lāʻau no 4 mau pule a ukali ʻia e 2 a 8 mau pule ke hāʻawi ʻole ʻia ka lāʻau. Kapa ʻia kēia wā lapaʻau he pōʻaiapuni, a hiki ke hana hou ʻia ke kalapona ke kūpono. Pili ka lōʻihi o ka mālama ʻana pehea ʻoe e pane ai i ka lāʻau.

Pono paha kāu kauka e hoʻolohi i kāu lāʻau, hoʻololi i kāu lāʻau, a i ʻole hoʻokū i kāu lāʻau inā ʻike ʻoe i kekahi mau hopena ʻaoʻao. He mea nui iā ʻoe e haʻi i kāu kauka i kou ʻano i kou wā e mālama ai me ka inikina blinatumomab.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka loaʻa ʻana o ka inikina blinatumomab,

• e haʻi aku i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka blinatumomab, nā lāʻau ʻē aʻe, ʻalekohola benzyl. a i ʻole nā ​​mea hoʻohui ʻē aʻe i ka inikina blinatumomab. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E hoʻomaopopo pono e haʻi i kekahi o kēia mau mea: cyclosporine (Gengraf, Neoral, Sandimmune) a i ʻole warfarin (Coumadin, Jantoven). Pili pū paha nā lāʻau ʻē aʻe he nui me ka blinatumomab, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka inā loaʻa ʻoe i ka maʻi ʻaʻai a inā he maʻi paha kāu a i ʻole hoʻi e hoʻi mai paha. Eia kekahi, e haʻi aku i kāu kauka inā ua loaʻa ʻoe i kahi radiation radiation i ka lolo a i ʻole ua loaʻa iā chemotherapy a i ʻole loaʻa paha iā ʻoe i ka maʻi ate.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. Pono ʻoe e hana i kahi hōʻike hāpai ma mua o ka loaʻa ʻana o kēia lāʻau iā ʻoe. ʻAʻole ʻoe e hāpai i ka wā o kāu mālama ʻana me blinatumomab a no 2 mau lā ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā ʻano o ka kaohi hānau e holo pono nāu. Inā hāpai ʻoe i ka hoʻohana ʻana i ka blinatumomab, e kāhea i kāu kauka. Hiki paha iā Blinatumomab ke hōʻeha i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. Mai hānai i ka wā e loaʻa ana iā blinatumomab a no ka liʻiliʻi he 2 mau lā ma hope o kāu hopena hope loa.
• pono ʻoe e ʻike i ka pīhoihoi o ka blinatumomab e hiamoe ai ʻoe. Mai hoʻokele i kahi kaʻa a hana hana paha i ka mīkini ke loaʻa iā ʻoe kēia lāʻau.
• ʻaʻohe o nā lāʻau āpau ke kamaʻilio ʻole ʻia me kāu kauka. E haʻi i kāu kauka inā ua loaʻa iā ʻoe kahi lāʻau lapaʻau i loko o 2 mau pule i hala. Ma hope o kāu hopena hope loa, e haʻi aku kāu kauka iā ʻoe ke palekana ke kiʻi ʻana i kahi lāʻau lapaʻau.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

Hoʻokumu paha ka pīhoihoi Blinatumomab i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• kōpaʻa
• pāhoehoe
• loaʻa kaupaona
• kua, ami, a ʻeha ʻeha paha
• ka pehu ʻana o nā lima, nā lima, nā wāwae, nā kuʻekuʻe wāwae, a i nā wāwae lalo
• ʻeha ma ka pūnaewele kaha

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i nā ʻARlelo AOAO PAHAʻOHE a i ʻole nā ​​kaʻina kūikawā, e kelepona koke i kāu kauka a i ʻole e kiʻi i nā lāʻau lapaʻau pilikia.

• ʻeha ka umauma
• numbness a ʻūlū paha i nā lima, nā wāwae, nā lima a me nā wāwae
• pokole o ka hanu
• ʻeha mau e hoʻomaka i ka wahi o ka ʻōpū akā hiki ke pālahalaha i ka hope i hiki ke kū ʻia me ka ʻole a me ka ʻole a me ka luaʻi
• fiva, ʻāʻī puʻupuʻu, batukū, a me nā ʻōuli ʻē aʻe o ka maʻi

Hiki i ke kīpona Blinatumomab ke kumu i nā hopena ʻē aʻe. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau i ka loaʻa ʻana o kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

• fiva
• luliluli ʻole ʻana i kahi ʻāpana o ke kino
• ʻeha poʻo

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab ma mua, i ka wā, a ma hope o kāu mālama ʻana e nānā i ka pane o kou kino i ka inikina blinatumomab a e mālama i nā hopena ma mua o ka lilo ʻana i mea koʻikoʻi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Blincyto^®