Mea Kākau: Janice Evans
Lā O Ka Hana: 23 Iulai 2021
HōʻAno Hou I Ka Lā: 17 Nowemapa 2024
Anonim
Immunotherapy and Radioimmunotherapy
Wikiō: Immunotherapy and Radioimmunotherapy

Anter

He mau hola ma mua o ka hāʻawi ʻana o kēlā me kēia kaha o ibritumomab injection, hāʻawi ʻia kahi lāʻau i kapa ʻia ʻo rituximab (Rituxan). Ua loaʻa i kekahi poʻe maʻi ka hopena a weliweli paha i ka hopena o ke ola a loaʻa iā lākou ka rituximab a i ʻole ma hope koke iho o ka loaʻa ʻana o ka rituximab. Ua hana pinepine ʻia kēia mau hopena me ka mahele mua o rituximab. Ua make kekahi mau maʻi ma loko o 24 mau hola ma hope o ka loaʻa ʻana o ka rituximab. E haʻi aku i kāu kauka inā he maʻi ʻoe i ka rituximab a i ʻole nā ​​lāʻau i hana ʻia mai nā protein murine (ʻiole), a i ʻole inā ʻaʻole ʻoe e ʻike inā ʻo kahi lāʻau āu e maʻi ai e hana ʻia mai nā protein murine. E haʻi aku i kāu kauka inā ua mālama ʻia ʻoe me kahi lāʻau i hana ʻia mai nā protein murine. Inā pēlā, loaʻa paha ʻoe i kahi hopena maʻi ʻaʻai i rituximab. E kauoha kāu kauka i nā hoʻokolohua e ʻike inā loaʻa paha ʻoe i ka hopena maʻi i ka rituximab.

E hāʻawi aku kāu kauka iā ʻoe i ka lāʻau ma mua o ka loaʻa ʻana o ka rituximab e kōkua ai i ka pale ʻana i nā hopena i ka rituximab. Inā ʻike ʻoe i kahi hopena i ka rituximab, hiki i kāu kauka ke hoʻopau i ka hāʻawi ʻana iā ʻoe i ka lāʻau no kekahi manawa a hāʻawi lohi paha iā ʻoe. Inā koʻikoʻi ka hopena, e hōʻoki ke kauka i ka infusion rituximab a ʻaʻole e hoʻomau i kāu mālama ʻana me ka inikū ibritumomab. E haʻi koke i kāu kauka inā ʻike ʻoe i kekahi o nā ʻōuli ma hope a i ʻole a ma hope koke paha o kou lapaʻau ʻana me rituximab: batukū; pilikia i ka hanu ʻana a i ʻole ke ale ʻana; ke ʻāʻī ʻana o ka ʻāʻī; hives; ʻumeʻume; pehu o nā maka, maka, lehelehe, alelo, waha, a ʻāʻī paha; ʻeha ma ka umauma, ʻāʻī, lima, kua, ʻāʻī; huikau; nalowale o ka ʻike; puʻuwai wikiwiki; kāhili; ʻili mae; hanu wikiwiki; hoʻemi i ka urination; aiʻole nā ​​lima a me nā wāwae anu.


ʻO ka mālama ʻana me ka rituximab a me ka injection ibritumomab i kumu e hōʻemi nui ai i nā helu o ke koko i kou kino. Hiki i kēia hōʻemi ke hana i 7 a 9 mau pule ma hope o kāu lapaʻau ʻana a mau paha no 12 mau pule a ʻoi paha. Hiki i kēia hoʻoliʻiliʻi ke kumu i nā maʻi ʻino a weliweli paha i ke ola a i ʻole ke kahe ʻana i ke kahe. ʻAʻole hāʻawi kāu kauka iā ʻoe i ka injection ibritumomab inā ua loli nui ʻia kou mau hunaola koko e ka maʻi ʻaʻai, inā loaʻa iā ʻoe kahi hoʻoneʻe iwi iwi, inā ʻaʻole hiki iā ʻoe ke hana i nā ʻōpala i lawa (nā hunaola i loaʻa i ka iwi iwi i hiki ke oʻo e hana. i kekahi ʻano o ke koko) e loaʻa i kahi iwi o ka iwi, a inā he helu haʻahaʻa kāu o nā huna koko. E haʻi i kāu kauka inā e lawe nei ʻoe i kekahi o nā lāʻau aʻe: anticoagulants ('blood thinners') e like me warfarin (Coumadin, Jantoven); aspirin a me nā lāʻau anti-inflammatory nonsteroidal (NSAIDs) e like me ibuprofen (Advil, Motrin) a me naproxen (Aleve); and clopidogrel (Plavix). Inā loaʻa iā ʻoe kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: ʻili mae; nāwaliwali; ʻehaʻeha a hoʻokahe koko paha; nā kiko poni a i ʻole nā ​​pākuʻi ma ka ʻili; pahu noho ʻeleʻele a koko paha; ka luaʻi he koko a nānā paha e like me ka papa kope; pāhoehoe; a ʻeha ʻeha paha, kuni, haʻalulu, ʻū, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi.


ʻO ka mālama ʻana me ka rituximab a me ka injection ibritumomab e hana i nā hopena o ka ʻili koʻikoʻi a maikaʻi paha. Hiki ke hana i kēia mau hopena i kekahi mau lā ma hope o ka mālama ʻana a i ʻole 4 mau mahina ma hope o ka lapaʻau. E haʻi koke i kāu kauka inā hoʻomohala ʻoe i kou ʻili a i ʻole ma loko o kou waha a ihu paha, kahi ʻāʻī, a me ka ʻili ʻana o ka ʻili. ʻAʻole hāʻawi kāu kauka iā ʻoe i kahi hou hou o ibritumomab inā ʻoe e hoʻomohala i kēia mau ʻōuli.

Ma hope o kou loaʻa ʻana i kāu mahele lāʻau mua o ka hoʻopili ʻana i ka ibritumomab, e kauoha kāu kauka i nā kiʻi paʻi kiʻi (nā hōʻike e hōʻike ana i kahi kiʻi o nā mea āpau a i ʻole ʻāpana o loko o ke kino) e ʻike ai i ka hoʻolaha ʻana o ka lāʻau i loko o kou kino. Inā ʻaʻole i pālahalaha ka lāʻau i loko o kou kino e like me ka mea i manaʻo ʻia, ʻaʻole ʻoe e loaʻa i kāu kauka ʻelua o ka inikū i ibritumomab.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua i ka wā o kāu mālama ʻana a a i ʻekolu mau mahina ma hope o kou mālama ʻana e nānā i ka pane o kou kino i ka inikopa i ibritumomab.


E kamaʻilio me kāu kauka e pili ana i ka makaʻu o ka loaʻa ʻana o ka inikō o ibritumomab.

Hoʻohana ʻia ʻo injitumomab injection me ka rituximab (Rituxan) e mālama ai i kekahi ʻano o ka lymphoma non-Hodgkin (NHL; ka maʻi ʻaʻai e hoʻomaka i nā hunaola o ka ʻōnaehana pale) ʻaʻole i hoʻomaikaʻi a i ʻole nā ​​mea i hoʻomāhuahua ma hope o ka mālama ʻana me nā lāʻau ʻē aʻe. Hoʻohana ʻia ia e mālama i kekahi ʻano o ka NHL i ka poʻe i hoʻomaikaʻi ma hope o ka mālama ʻana me nā lāʻau chemotherapy ʻē aʻe. ʻO ka lāʻau injection Ibritumomab i loko o ka papa o nā lāʻau i kapa ʻia he monoclonal antibodies me radioisotopes. Hana ia e ka hoʻopili ʻana i nā hunaola maʻi ʻaʻai a hoʻokuʻu i ka radiation e hōʻino ai i nā hunaola maʻi ʻaʻai.

Ua hele mai ʻo Ibritumomab injection e like me ka wai e hoʻokomo ʻia i loko o ke aa i 10 mau minuke e ke kauka i aʻo ʻia e mālama i nā mea maʻi me ka lāʻau radioactive. Hāʻawi ʻia ia ma kahi ʻāpana o kahi regimen lapaʻau maʻi ʻaʻai. I ka lā mua o ke kaʻina hana lapaʻau, hāʻawi ʻia kahi mahele o rituximab a hāʻawi ʻia ka mahele mua o ka hoʻopili ʻana o ibritumomab ma mua o 4 mau hola ma hope. ʻImi ʻia nā kiʻi e ʻike ai i ka palahalaha ʻana o ka inikū ibritumomab ma loko o ke kino e hana ʻia 48 a 72 mau hola ma hope o ka hāʻawi ʻia ʻana o ka lāʻau. Hiki ke hana ʻia i kahi scan hou inā pono i nā lā hou e hiki mai ana. Inā hōʻike nā hopena o ka scan (s) ua pālahalaha ʻia ka pahu i loko o ke kino e like me ka mea i manaʻo ʻia, hāʻawi ʻia kahi mahele ʻelua o ka rituximab a me ka lua o ka mahele lāʻau o ibritumomab 7 a 9 mau lā ma hope o ka hāʻawi ʻia ʻana o nā kau mua.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka loaʻa ʻana o ka injection ibritumomab,

  • e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka ibritumomab, kekahi o nā lāʻau i ʻōlelo ʻia i ka ʻĀINA WAIWAI, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i ka inikū ibritumomab. E noi i kāu kauka a kauka paha no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, nā mea hoʻopihaʻai, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe E ʻōlelo pono i nā lāʻau i helu ʻia i ka ʻARlelo Aʻo IMPORTANT. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
  • e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa i kekahi ʻano olakino.
  • e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. ʻAʻole pono ʻoe e hāpai i ka wā e loaʻa ana iā ʻoe ʻo ibritumomab. Inā he wahine ʻoe, pono ʻoe e lawe i kahi hōʻike hāpai ma mua o ka hoʻomaka ʻana o ka lāʻau ʻana a hoʻohana i ka kaohi hānau e pale ai i ka hāpai ʻana i kāu wā lapaʻau a no 12 mau mahina ma hope o kāu hopena hope loa Inā he kāne ʻoe me kāu hoa wahine, e hoʻohana i ka kaohi hānau e pale ai i ka hāpai ʻana i kāu wā e mālama ai a no 12 mau mahina ma hope o kāu hopena hope loa. Inā hāpai ʻoe a ʻo kāu hoa paha i ka loaʻa ʻana o ka injection ibritumomab, e kāhea koke i kāu kauka. Hoʻopilikia paha ka piʻo Ibritumomab i ka fetus.
  • e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū a i ʻole hoʻolālā e hānai. ʻAʻole pono ʻoe e hānai i ka wā e loaʻa ana iā ibritumomab a no 6 mau mahina ma hope o kāu hopena hope loa.
  • pono ʻoe e ʻike i kēia lāʻau i hoʻemi ai i ka momona i nā kāne a me nā wahine. E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka loaʻa ʻana o ka ibritumomab.
  • inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o nā niho, e haʻi i ke kauka a i ʻole kauka niho ua loaʻa iā ʻoe ka injection ibritumomab.
  • ʻaʻohe o nā lāʻau lapaʻau i ka wā o ka mālama ʻana a no 12 mau mahina ma hope o kāu hopena hope loa me ke kamaʻilio ʻole mua ʻole ʻana me kāu kauka.
  • pono ʻoe e ʻike i ka lekiō ʻana i ka mahele ʻelua o ka hoʻopili ʻana o ibritumomab i loko o kou kino wai a hiki i hoʻokahi pule ma hope o kou loaʻa ʻana o ka lāʻau. I mea e pale aku ai i ka lekiō ʻana mai ka hoʻolaha ʻana aku i ka poʻe e launa pū ana me ʻoe, pono ʻoe e holoi pono i kou mau lima ma hope o ka hoʻohana ʻana i ka lumipaku, e hoʻohana i ka pale pale i kēlā me kēia manawa ke moe kolohe ʻoe, a pale i ka honi hohonu ʻana. E hāhai i kēia mau akahele i ka wā o kāu mālama ʻana a no 7 mau lā ma hope o kou loaʻa ʻana o kāu kaukana ʻelua o ka inikōlani ibritumomab.
  • pono ʻoe e ʻike ʻo ka inikū i ibritumomab kahi albumin (kahi huahana i hana ʻia mai ke koko hāʻawi ola). ʻOiai loaʻa kahi manawa liʻiliʻi e hoʻolaha ʻia nā mea ʻino ma o ke koko, ʻaʻole i hōʻike ʻia nā hihia o nā maʻi viral mai kēia huahana.
  • pono ʻoe e ʻike inā loaʻa ʻoe i ka injection ibritumomab, hiki i kou kino ke hoʻomohala i nā mea pale (nā mea i loko o ke koko e kōkua ai i ka ʻōnaehana pale e ʻike a hoʻouka i nā mea haole) e murine proteins Inā hoʻomohala ʻoe i kēia mau mea ʻumeʻume, loaʻa paha iā ʻoe kahi hopena maʻi maʻi ke lawe ʻoe i nā lāʻau i hana ʻia mai nā protein murine, a i ʻole ʻaʻole holo pono kēia mau lāʻau iā ʻoe. Ma hope o kāu lapaʻau ʻana me ka inikū o ibritumomab, e haʻi pono i kāu kauka āpau. mālama ʻia me ka hoʻopili ʻana o ibritumomab.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

Kāhea koke i kāu kauka inā ʻaʻole hiki iā ʻoe ke mālama i kahi manawa e loaʻa ai ka inikū i loko o ka ibritumomab.

Hiki i nā inikua ʻo Ibritumomab ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • nausea
  • ka luaʻi
  • ʻeha o ka ʻōpū a huʻi paha
  • kōpaʻa
  • puʻuwai puʻuwai
  • nalo ʻai ʻole
  • ʻeha poʻo
  • hopohopo
  • ʻūpā
  • paʻakikī e hiamoe a hiamoe paha
  • kua, ami, a ʻeha ʻeha paha
  • ʻōhinu

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o nā ʻōuli i helu ʻia ma ka ʻĀINA AOAO PAHU a i ʻole o kekahi o nā ʻōuli aʻe, e kāhea koke i kāu kauka.

  • ʻulaʻula, palupalu, a i ʻole kahi ʻeha hāmama i ka wahi i ʻami ʻia ka lāʻau

ʻO kekahi poʻe i loaʻa i ka injection ibritumomab i hoʻomohala i nā ʻano ʻano ʻē aʻe o ka maʻi ʻaʻai e like me leukemia (maʻi ʻaʻai e hoʻomaka ana i nā hunaola keokeo) a me myelodysplastic maʻi (kahi e ulu maʻamau ʻole ai nā hunaola koko) i nā makahiki mua ma hope o ka loaʻa ʻana o ka lāʻau. E kamaʻilio me kāu kauka e pili ana i ka makaʻu o ka loaʻa ʻana o kēia lāʻau.

Hoʻokumu paha ka pahu i Ibritumomab i nā hopena ʻē aʻe. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau i ka loaʻa ʻana o kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

  • ʻili mae
  • nāwaliwali
  • pokole o ka hanu
  • luhi nui loa
  • ʻāpā ʻaʻano ʻole a hoʻokahe koko paha
  • nā poni poni a i ʻole nā ​​palaka ma ka ʻili
  • ʻeha ka ʻāʻī, ke kuni, ke anu, ka ʻū, a me nā hōʻailona ʻē aʻe o ka maʻi

E nīnau i kāu kauka a kauka paha i kāu mau nīnau e pili ana i ka inikōnia ʻo ibritumomab.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

  • Zevalin®
Nānā Hou - 02/15/2019

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