Mea Kākau: Marcus Baldwin
Lā O Ka Hana: 18 Iune 2021
HōʻAno Hou I Ka Lā: 16 Nowemapa 2024
Anonim
Posaconazole (Non Inferiority Trial) vs Voriconazole in Invasive Aspergillosis
Wikiō: Posaconazole (Non Inferiority Trial) vs Voriconazole in Invasive Aspergillosis

Anter

Hoʻohana ʻia ʻo Posaconazole i nā papa hoʻokuʻu lohi a hoʻokuʻu ʻia i ka waha e pale ai i nā maʻi fungal koʻikoʻi i nā mākua a me nā ʻōpio 13 mau makahiki a ʻoi aku me ka hiki i ka nāwaliwali ke hakakā i ka maʻi. Hoʻohana pū ʻia ka Posaconazole oral suspending e mālama i nā maʻi hū o ka waha a me ka puʻu me nā maʻi hū i hiki ʻole ke mālama kūleʻa ʻia me nā lāʻau ʻē aʻe. ʻO Posaconazole kahi papa o nā lāʻau i kapa ʻia ʻo azole antifungals. Hana ia me ka hoʻolohi i ka ulu ʻana o nā fungi i kumu i ka maʻi.

Hele mai ʻo Posaconazole ma ke ʻano he wehe waha (wai) a ma ke ʻano he lohi-hoʻokuʻu (hoʻokuʻu i ka lāʻau i loko o ka ʻōpū e pale i ka haki ʻana o ka lāʻau lapaʻau e nā ʻōpū ʻōpū) e lawe ma ka waha. Lawe pinepine ʻia nā papa hoʻolohi lohi me ka ʻai i ʻelua mau lā i ka lā mua a laila hoʻokahi i ka lā. Lawe pinepine ʻia ka hoʻomaha waha ma ʻekolu mau manawa i ka lā me kahi pāʻina piha a i ʻole ma loko o 20 mau minuke ma hope o ka pāʻina ʻana. Inā ʻaʻole hiki iā ʻoe ke lawe i ke kau ʻana o ka waha me kahi papaʻai piha, e lawe iā ia me kahi mea kōkua a me nā mea inu wai ʻona e like me ka ale ale. E hoʻoholo kāu kauka i ka lōʻihi e pono ai ʻoe e hoʻohana i kēia lāʻau. Lawe iā posaconazole ma nā manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pololei i ka posaconazole e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.


E hoʻoluliluli maikaʻi i ka hoʻopiʻi waha ma mua o kēlā me kēia hoʻohana e kāwili kaulike i ka lāʻau.

E hoʻohana mau i ka puna o ka dosing e hiki mai me ka pani waha waha posaconazole e ana i kāu lāʻau. ʻAʻole paha ʻoe e loaʻa i ka nui o ka lāʻau lapaʻau inā hoʻohana ʻoe i ka puna o ka home e ana i kāu lāʻau. Pono e holoi pono i ka puna me ka wai ma hope o kēlā me kēia hoʻohana a ma mua o ka mālama ʻana.

E ale i ka posaconazole hoʻopaneʻe-hoʻokuʻu i nā papa holoʻokoʻa; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou. Inā ʻaʻole hiki iā ʻoe ke ale i nā papa hoʻokuʻu hoʻokuʻu lohi, e haʻi i kāu kauka.

Hoʻokuʻu kēlā me kēia huahana posaconazole i ka lāʻau i loko o kou kino a ʻaʻole hiki ke hoʻohana ʻia me ka loli.Lawe wale i ka huahana posaconazole i kuhikuhi ʻia e kāu kauka a mai hoʻololi ʻoe i kahi huahana posaconazole ʻokoʻa ke ʻole kauka a kāu kauka e pono ai.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.


Ma mua o ka lawe ʻana i ka posaconazole,

  • e haʻi i kāu kauka a me ka kauka inā ua maʻi ʻoe i ka posaconazole; nā lāʻau antifungal ʻē aʻe e like me fluconazole (Diflucan), isavuconazonium (Cresemba), itraconazole (Onmel, Sporanox), ketoconazole (Extina, Nizoral, Xolegel), a i ʻole voriconazole (Vfend); simethicone; nā lāʻau lapaʻau ʻē aʻe; aiʻole kekahi o nā mea hoʻohui i nā huahana posaconazole. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka inā lawe ʻoe i kekahi o nā lāʻau aʻe: atorvastatin (Lipitor, ma Caduet), nā lāʻau lapaʻau ʻano ʻē aʻe e like me bromocriptine (Cycloset, Parlodel), cabergoline, dihydroergotamine (DHE 45, Migranal), ergoloid mesylates (Hydergine), ergonovine , ergotamine (Ergomar, ma Cafergot, ma Migergot), a me methylergonovine (Methergine); lovastatin (Altoprev, i Advicor); pimozide (Orap); quinidine (i Nuedexta); simvastatin (Zocor, ma Simcor, ma Vytorin); aiʻole sirolimus (Rapamune). E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka posaconazole inā ʻoe e lawe i hoʻokahi aʻoi aku paha o kēia mau lāʻau.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E kuhikuhi pono i kekahi o kēia mau mea: benzodiazepines e like me alprazolam (Xanax), diazepam (Valium), midazolam, a me triazolam (Halcion); nā poloka kalipuna e like me diltiazem (Cardizem, Cartia, Tiazac, a me nā mea ʻē aʻe), felodipine, nicardipine (Cardene), nifedipine (Adalat, Afeditab CR, Procardia), a me verapamil (Calan, Covera, Verelan, a me nā mea ʻē aʻe); cyclosporine (Gengraf, Neoral, Sandimmune); digoxin (Lanoxin); efavirenz (Sustiva, i Atripla); erythromycin (E.E.S., ERYC, Erythrocin, nā mea ʻē aʻe), fosamprenavir (Lexiva); glipizide (Glucotrol); phenytoin (Dilantin, Phenytek); rifabutin (Mycobutin); lawe ʻia ʻo ritonavir (Norvir) me atazanavir (Reyataz); tacrolimus (Astagraf, Envarsus XR, Prograf); vinblastine; a me vincristine (Marquibo Kit). Inā ʻoe e lawe ana i ka pani waha waha posaconazole, e haʻi aku i kāu kauka inā ʻoe e lawe ana i ka cimetidine (Tagamet), esomeprazole (Nexium, ma Vimovo), a i ʻole metoclopramide (Reglan). Hiki ke launa pū kekahi me nā lāʻau ʻē aʻe he nui me ka posaconazole, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
  • e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa paha i kahi puʻuwai lohi a i ʻole maʻamau. kahi wā QT hoʻolōʻihi (kahi pilikia puʻuwai laha ʻole e hiki ai ke hōʻeha i ka puʻuwai ʻole, maʻule, a make koke paha); nā pilikia me ke kahe o ke koko; nā pae haʻahaʻa o ka calcium, magnesium, a i ʻole potassium i kou koko; a i ʻole ka hakuʻala, a i ʻole ka maʻi ate.
  • e haʻi i kāu kauka inā hāpai ʻoe, hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana i ka posaconazole, e kāhea i kāu kauka.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.


Inā ʻoe e lawe ana i ka hoʻopaneʻe waha, lawe i ka lāʻau i hala i kou hoʻomanaʻo ʻana iā ia. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Inā ʻoe e lawe i nā papa hoʻokuʻu hoʻokuʻu lohi, lawe i ka lāʻau i hala i kou hoʻomanaʻo ʻana iā ia. Eia nō naʻe, inā aia ma waena o 12 mau hola o kāu kau ma hope, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hiki i ka Posaconazole ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • fiva
  • ʻeha poʻo
  • haʻalulu a luliluli paha
  • ʻūpā
  • nāwaliwali
  • ka pehu o nā lima, ka wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
  • pāhoehoe
  • ka luaʻi
  • ʻeha ka ʻōpū
  • kōpaʻa
  • puʻuwai puʻuwai
  • hūwī
  • ʻūlili
  • ʻeha ke kua a ʻeha hoʻi
  • ʻeha ma nā lehelehe, waha, a ʻāʻī paha
  • paʻakikī e hiamoe a hiamoe paha
  • hoʻonui sweating
  • ihu ihu
  • ʻūhā
  • eha ka 'ā'ī

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻĀLU MAKAHIKI kūikawā, e kāhea koke i kāu kauka:

  • ʻāpā ʻaʻano ʻole a hoʻokahe koko paha
  • luhi loa
  • nele i ka ikaika
  • nalo ʻai ʻole
  • nausea
  • ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū
  • melemele o ka ʻili a me nā maka
  • nā ʻōuli like flu
  • mimi ʻeleʻele
  • noho humuhumu
  • wikiwiki, kuʻi, a i ʻole kuʻi puʻuwai puʻuwai
  • nalowale koke ʻana o ka ʻike
  • pokole o ka hanu

Hiki i ka Posaconazole ke hana i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua. Mai hoʻopaʻa i ka hoʻokuʻu waha.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka posaconazole.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi. Inā loaʻa iā ʻoe nā ʻōuli o ka maʻi ma hope o kou hoʻopau ʻana i ka posaconazole, e kāhea i kāu kauka.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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