Hōʻike Troponin
Ana ke ana o ka troponin i nā pae o ka troponin T a i ʻole nā proteinsin I i loko o ke koko. Hoʻokuʻu ʻia kēia mau protein i ka wā i hōʻino ʻia ka puʻuwai puʻuwai, e like me ka hopena o ka puʻuwai. ʻO ka nui o ka hōʻino o ka puʻuwai, ʻo ka nui o ka troponin T a ʻo wau i loko o ke koko.
Pono kahi laʻana koko.
ʻAʻole pono nā ʻanuʻu kūikawā e hoʻomākaukau ai, i ka hapa nui o ka manawa.
Hiki paha iā ʻoe ke ʻeha iki a i ʻole ke kuʻi ke hoʻokomo ʻia o ka nila. Hiki paha iā ʻoe ke hāwele i kahi kani ma ka pūnaewele ma hope o ka huki ʻia ʻana o ke koko.
ʻO ke kumu maʻamau e hana ai i kēia hoʻokolohua e ʻike inā ua kū kahi puʻuwai puʻuwai. E kauoha kāu mea mālama ola i kēia hōʻoia inā loaʻa iā ʻoe ka ʻeha o ka umauma a me nā hōʻailona ʻē aʻe o ka puʻuwai puʻuwai. Hoʻomaʻa pinepine ʻia ka hōʻike i ʻelua mau manawa hou aʻe ma mua o 6 a 24 mau hola.
E kauoha paha kāu mea hāʻawi i kēia hoʻāʻo inā loaʻa ka angina i ka maikaʻi ʻole, akā ʻaʻohe hōʻailona ʻē aʻe o ka puʻuwai puʻuwai. (Angina ka ʻeha o ka umauma i manaʻo ʻia mai kahi ʻāpana o kou puʻuwai e lawa ʻole ana ke kahe o ke koko.)
Hiki ke hana ʻia ka hōʻike troponin e kōkua ai e ʻike a loiloi i nā kumu ʻē aʻe o ka hōʻeha puʻuwai.
E hana ʻia paha ka hoʻāʻo me nā hoʻokolohua mākaʻi puʻuwai ʻē aʻe, e like me CPK isoenzymes a i ʻole myoglobin.
Maʻamau ka pae o ka cardiac troponin pae hiki ʻole ke ʻike ʻia me ka nui o nā hoʻokolohua koko.
Loaʻa i nā pae troponin maʻamau he 12 mau hola ma hope o ka hoʻomaka ʻana o ka ʻeha o ka umauma ʻo ia hoʻi ʻaʻole hiki i ka puʻuwai puʻuwai.
Hiki ke hoʻololi iki i kahi pae waiwai maʻamau i waena o nā hale hana ʻokoʻa. Hoʻohana kekahi mau labs i nā ana like ʻole (e laʻa me, "hoʻāʻo kiʻekiʻe troponin hōʻoia") a i ʻole e hoʻāʻo i nā laʻana like ʻole Eia kekahi, he mau helu ʻoki ʻokoʻa kā kekahi mau labs no "normal" a me "infarction myocardial probable." E kamaʻilio i kāu mea hāʻawi e pili ana i ke ʻano o kāu mau hopena hōʻike.
ʻOiai ka hoʻonui iki ʻana o ka pae troponin e manaʻo pinepine ia ua loaʻa kekahi mau pōʻino i ka puʻuwai. ʻO nā pae kiʻekiʻe loa o troponin kahi hōʻailona e kū kahi puʻuwai puʻuwai.
ʻO ka hapa nui o nā mea maʻi i loaʻa i ka puʻuwai puʻuwai e hoʻonui i nā pae troponin i loko o 6 mau hola. Ma hope o 12 mau hola, kokoke i kēlā me kēia mea i loaʻa i ka puʻuwai puʻuwai e hoʻonui i nā pae.
Hiki ke kiʻekiʻe nā pae Troponin no 1 a 2 mau pule ma hope o ka puʻuwai puʻuwai.
Hoʻonui ʻia paha nā pae troponin ma muli o:
- Kuʻi puʻuwai wikiwiki Abnormally
- ʻO ke koko kiʻekiʻe i nā aʻa māmā (hypertension pulmonary)
- ʻO ka pale ʻana o ke aʻa māmā e ke kōkō ʻana o ke koko, momona, a i ʻole nā hunaola tumole (pulmonary embolus)
- Hoka puʻuwai Congestive
- Spasm artery spasm
- ʻO ka hoʻohaunaele o ka puʻuwai puʻuwai ma muli o ka maʻi (myocarditis)
- Hoʻolālā lōʻihi (e laʻa me ka marathons a i ʻole triathlons)
- Trauma hōʻeha i ka puʻuwai, e like me kahi ulia kaʻa
- Hoʻonāwaliwali o ka naʻau Muscle (cardiomyopathy)
- Maʻi maʻi ʻōuli lōʻihi
Hiki ke hopena ʻia nā pae troponin i hoʻonui ʻia mai kekahi mau kaʻina olakino e like me:
- Cardiac angioplasty / stenting
- ʻO ka defibrillation puʻuwai a i ʻole cardioversion uila (kumu hoʻohilahila i ka puʻuwai e nā limahana lapaʻau e hoʻoponopono i kahi puʻuwai puʻuwai maʻamau)
- ʻOki puʻuwai puʻuwai
- ʻO ka hoʻolei radiofrequency o ka puʻuwai
TroponinI; TnI; TroponinT; TnT; ʻO troponin kikoʻī Cardiac; ʻO ka troponin kikoʻī Cardiac; cTnl; cTnT
Bohula EA, ʻApōpō DA. ST-Kiʻi myocardial infarction: hoʻokele. I: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. ʻO ka maʻi puʻuwai ʻo Braunwald: He puke aʻo no ka lāʻau Cardiovascular. 11th hua. Piladelapia, PA: Elsevier; 2018: chap 59.
Bonaca, MP, Sabatine MS. Hele i ka mea maʻi me ka ʻeha o ka umauma. I: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. ʻO ka maʻi puʻuwai ʻo Braunwald: He puke aʻo no ka lāʻau Cardiovascular. 11th hua. Piladelapia, PA: Elsevier; 2019: chap 56.
ʻO Levine GN, ʻo Bates ER, Blankenship JC, et al. 2015 ACC / AHA / SCAI Hoʻolālā hou ʻia i ka hoʻopili mua coronary percutaneus no nā mea maʻi me ka infarction myocardial ST-Kiʻekiʻena: kahi hou o ka 2011 ACCF / AHA / SCAI alakaʻi no ka hoʻopili coronary percutaneus a me ka 2013 ACCF / AHA alakaʻi no ka mālama ʻana i ST- Ka hoʻohaunaele myocardial infarction: kahi hōʻike o ka American College of Cardiology / American Heart Association Task Force e pili ana i nā kulekele hana lapaʻau a me ka Society for Angiography a me nā Interience Cardiovascular. Kaapuni. 2016; 133 (11): 1135-1147. PMID: 26490017 www.ncbi.nlm.nih.gov/pubmed/26490017.
Thygesen K, Alpert JS, Jaffe AS, Chaitman BR, Bax JJ, Morrow DA, Keʻokeʻo HD; Pūʻulu Hoʻokele ma ka inoa o ka Joint European Society of Cardiology (ESC) / American College of Cardiology (ACC) / American Heart Association (AHA) / World Heart Federation (WHF) Task Force no ka Universal Definition of Myocardial Infarction. ʻO ka wehewehe ʻehā o ka myocardial infarction (2018). Kaapuni. 2018; 138 (20): e618-e651 PMID: 30571511 www.ncbi.nlm.nih.gov/pubmed/30571511.