ʻO ka pae Vitamin B12

ʻO ka pae vitamin B12 kahi hōʻoia koko e ana i ka nui o ka wikamina B12 i loko o kou koko.

Pono kahi laʻana koko.

ʻAʻole ʻoe e ʻai a inu paha ma kahi o 6 a 8 mau hola ma mua o ka hoʻāʻo.

Hiki i kekahi mau lāʻau ke hoʻololi i nā hopena o kēia hōʻike. E haʻi aku kāu mea mālama ola inā pono ʻoe e hōʻoki i ka lawe ʻana i nā lāʻau. Mai hōʻoki i kekahi lāʻau ma mua o ke kamaʻilio ʻana i kāu mea hāʻawi.

Nā lāʻau i hiki ke hoʻololi i ka hopena hōʻike me:

• Colchisin
• Neomycin
• ʻAla para-aminosalicylic
• ʻO Phenytoin

Ke hoʻokomo ʻia ke kui kele e huki i ke koko, manaʻo kekahi poʻe i ka ʻeha kaulike. ʻIke wale kekahi i kahi ʻōniʻu a i ʻole kui. Ma hope, loaʻa paha i kahi kūpikipiki a i ʻole ka ʻūlū iki. Hele koke kēia.

Hana pinepine pinepine ʻia kēia hōʻike ke hōʻike nā hōʻike koko ʻē aʻe i kahi kūlana i kapa ʻia ʻo megaloblastic anemia. ʻO ka anemia Pernicious kahi ʻano o ka anemia megaloblastic i hoʻokumu ʻia e ka hopena maikaʻi ʻole o ka huaora B12. Hiki i kēia ke hana i ka ʻōpū e hoʻemi i ka mea e pono ai i ke kino e komo pono i ka lāʻau B12.

Hiki paha i kāu mea hoʻolako ke paipai i kahi hōʻike vitamin B12 inā loaʻa iā ʻoe kekahi mau ʻōuli ʻōnaehana. Hiki i kahi pae haʻahaʻa o B12 ke kumu i ka helu a i ʻole ka ʻūlū ʻana i nā lima a me nā wāwae, nāwaliwali, a me ka nalo ʻana o ke kaulike.

Nā kūlana ʻē aʻe e hana ʻia ai ka hōʻike me:

• Huikau nui loa (delirium)
• Ka nalowale ʻana o ka hana lolo (dementia)
• ʻO Dementia ma muli o nā kumu hana metabolic
• ʻO nā kino kīnā ʻole, e like me ke neuropathy ākea

ʻO nā kumukūʻai maʻamau he 160 a hiki i ka 950 picograms ma ka milliliter (pg / mL), a i ʻole 118 a 701 picomoles i kēlā me kēia lita (pmol / L).

Hiki ke loli iki nā pae waiwai maʻamau i waena o nā hale hana ʻokoʻa. Hoʻohana kekahi mau labs i nā ana like ʻole a i ʻole hoʻokolohua i nā laʻana like ʻole. E kamaʻilio i kāu mea hāʻawi e pili ana i ke ʻano o kāu mau hopena hōʻike.

ʻO nā kumukūʻai ma lalo o 160 pg / mL (118 pmol / L) he hōʻailona hiki ke loaʻa i ka hemahema o ka wikamina B12. ʻO ka poʻe me kēia hemahema e loaʻa a hoʻomōhala paha i nā ʻōuli.

ʻO nā mākua me ka pae vitamin B12 ma mua o 100 pg / ml (74 pmol / L) Pono e hōʻoia ʻia ka hemahema e ke kaha ʻana i ka pae o kahi mea i loko o ke koko i kapa ʻia ʻo ka methylmalonic acid. Kuhi kahi pae kiʻekiʻe i kahi hemahema B12 maoli.

Nā kumu o ka hemahema o ka wikamina B12:

• ʻAʻole lawa ka wikamina B12 i ka papaʻai (kākaʻikahi, koe wale nō me ka papaʻai vegetarian koʻikoʻi)
• Nā maʻi e kumu ai i ka malabsorption (e laʻa me ka maʻi celiac a me ka maʻi Crohn)
• Ka nele o ka intrinsic factor, kahi protein e kōkua ai i ka ʻōpū e omo i ka wikamina B12
• Ma luna o ka hana wela maʻamau (e laʻa me ka hyperthyroidism)
• Hapai keiki

ʻO ka nui o ka huaʻai B12 i hoʻonui ʻia he ʻike ʻole ʻia. ʻO ka maʻamau, hemo ka lāʻau huaʻai B12 i ka mimi.

Nā kūlana i hiki ke hoʻonui i ka pae B12 me:

• ʻO ka maʻi ate (e like me cirrhosis a i ʻole hepatitis)
• Nā maʻi Myeloproliferative (ʻo kahi laʻana, polycythemia vera a me ka leukemia myelogenous mau)

ʻAʻohe pilikia iki i ka lawe ʻia ʻana o kou koko. ʻOkoʻa nā aʻa a me nā aʻa i ka nui mai kekahi kanaka a i kekahi ʻē aʻe a mai kekahi ʻaoʻao o ke kino i kekahi. ʻOi aku ka paʻakikī o ka lawe ʻana i ke koko mai kekahi poʻe ma mua o nā poʻe ʻē aʻe.

ʻO nā pilikia ʻē aʻe e pili ana i ke kau ʻana o ke koko he liʻiliʻi, akā hiki ke hoʻopili ʻia:

• Kahe nui ke koko
• Pāleʻale a ʻoluʻolu paha
• Nā punctures he nui e ʻimi i nā uaua
• Hematoma (kūkulu koko ma lalo o ka ʻili)
• Maʻiʻaʻai (i iki kamepiula i kēlā me kēia manawa ka ʻili i haki)

Hōʻike ʻo Cobalamin; Peremia anemia - ʻokikū B12 pae

ʻO Marcogliese AN, Yee DL. Nā kumuwaiwai no ka hematologist: nā manaʻo wehewehe a me nā waiwai i koho ʻia no ka neonatal, pediatric, a me nā heluna makua. I: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Nā Kumumanaʻo a me ka Hoʻomeheu. ʻEpekema 7 Piladelapia, PA: Elsevier; 2018: chap 162.

ʻO Mason JB, Booth SL. ʻO nā wikamina, nā minela ukali, a me nā micronutrients ʻē aʻe. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 26th ed. Piladelapia, PA: Elsevier; 2020: chap 205.