Hōʻike T3RU
Ke ana nei ka hoʻāʻo T3RU i ke kiʻekiʻe o nā protein i hāpai i ka hormone thyroid i ke koko. Hiki i kēia ke kōkua i kāu kauka olakino e wehewehe i nā hopena o ka T3 a me ka T4 hōʻike i ke koko.
Ma muli o ke kāhea ʻia ʻana o nā hoʻokolohua koko T4 manuahi a me kouroxine paʻa paʻa ʻana i ka globulin (TBG) hiki ke loaʻa i kēia manawa, hoʻohana pinepine ʻole ʻia ka hōʻike T3RU i kēia mau lā.
Pono kahi laʻana koko.
E haʻi aku kāu mea lawelawe iā ʻoe inā pono ʻoe e hōʻoki i ka lawe ʻana i nā lāʻau i mua o ka hoʻokolohua e hoʻopili ai i kāu hopena hōʻike. Mai hōʻoki i ka lawe ʻana i nā lāʻau me ka ʻole e kamaʻilio mua i kāu mea hāʻawi.
ʻO kekahi mau lāʻau e hiki ai ke hoʻonui i nā pae T3RU me:
- ʻO nā steroid Anabolic
- Heparin
- ʻO Phenytoin
- Salicylates (kiʻekiʻe mahele lāʻau)
- Warfarin
ʻO kekahi mau lāʻau e hiki ai ke hōʻemi i nā pae T3RU me:
- Nā lāʻau Antithyroid
- Pila pale hānau
- Clofibrate
- Estrogen
- ʻO Thiazides
Hiki i ka hāpai ʻana ke hoʻoemi i nā pae T3RU.
Hiki i kēia mau kūlana ke hōʻemi i nā pae TBG (e nānā ma lalo o ka ʻāpana "No ke aha e hoʻokō ʻia ai ka hoʻokolohua" no nā mea hou aʻe e pili ana i ka TBG):
- Maʻi nui
- ʻO ka maʻi kīkī ke nalowale ka protein i ka mimi (nephrotic syndrome)
ʻO nā lāʻau ʻē aʻe e hoʻopaʻa i ka protein i ke koko hiki ke hoʻopili i nā hopena hōʻike.
Ke hoʻokomo ʻia ke kui kele e huki i ke koko, manaʻo kekahi poʻe i ka ʻeha kaulike. ʻIke wale kekahi i kahi ʻōniʻu a i ʻole kui. Ma hope, loaʻa paha i kahi kūpikipiki a i ʻole ka ʻūlū iki. Hele koke kēia.
Hana ʻia kēia hōʻike e nānā i kāu hana thyroid. Pili ka hana o ka thyroid i ka hana o nā hormones like ʻole, e like me ka thyroid-stimulate hormone (TSH), T3, a me T4.
Kōkua kēia hōʻike i ka helu o ka T3 i hiki i ka TBG ke hoʻopaʻa. ʻO ka TBG kahi protein e hāpai i ka hapa nui o ka T3 a me ka T4 i ke koko.
E ʻōlelo paha kāu mea hāʻawi i kahi hōʻike T3RU inā he mau hōʻailona kou no ka maʻi thyroid, e like me:
- Hyperthyroidism (overactive thyroid)
- Hypothyroidism (underactive thyroid)
- Thyrotoxic periodic paralysis (nāwaliwali o nā mākala i hoʻokumu ʻia e nā kiʻekiʻe o ka thyroid hormone i ke koko)
Loaʻa nā kumukūʻai maʻamau mai 24% a 37%.
Hiki ke loli iki nā pae waiwai maʻamau i waena o nā hale hana ʻokoʻa. Hoʻohana kekahi mau labs i nā ana like ʻole a i ʻole nā hoʻāʻo i nā laʻana like ʻole. E kamaʻilio i kāu mea hāʻawi e pili ana i ke ʻano o kāu mau hopena hōʻike.
Hōʻike nā pae kiʻekiʻe ma mua o ka maʻamau:
- Hewa ʻole nā hakuʻala
- ʻO ka nui o ka thyroid (hyperthyroidism)
- Nā maʻi Nephrotic
- Palena ʻai ʻole protein
Hōʻike nā pae haʻahaʻa ma mua o ka maʻamau:
- Huehue hepatitis (ake maʻi)
- Hapai keiki
- Hypothyroidism
- Hoʻohana o ka estrogen
Loaʻa paha nā hopena maʻamau ma muli o kahi kūlana hoʻoilina o nā kiʻekiʻe TBG kiʻekiʻe. ʻO ka maʻamau o ka hana thyroid i maʻamau i ka poʻe me kēia ʻano.
E hana ʻia paha kēia hōʻike no:
- ʻO ka thyroiditis maʻi (ka pehu a me ka mumū o ka momona thyroid, me ka maʻi Hashimoto)
- ʻO hypothyroidism i hoʻokomo ʻia i ka lāʻau
- Maʻi maʻi kupapaʻu
- ʻO ka sub thyroiditis
- ʻO ka paralysis kau manawa Thyrotoxic
- Pākuʻi nodular ʻona
Aia kahi pilikia iki i ka lawe ʻia ʻana o kou koko. Hoʻohālikelike nā aʻa a me nā aʻa i ka nui mai kekahi kanaka a i kekahi ʻē aʻe a mai kekahi ʻaoʻao o ke kino i kekahi. ʻOi aku ka paʻakikī o ka loaʻa ʻana o kahi laʻana koko mai kekahi poʻe ma mua o nā poʻe ʻē aʻe.
ʻO nā pilikia ʻē aʻe e pili ana i ke kau ʻana o ke koko he liʻiliʻi, akā hiki ke hoʻopili ʻia:
- Kahe nui ke koko
- Pāleʻale a ʻoluʻolu paha
- Nā punctures he nui e ʻimi i nā uaua
- Hematoma (kūkulu koko ma lalo o ka ʻili)
- Maʻiʻaʻai (i iki kamepiula i kēlā me kēia manawa ka ʻili i haki)
Hoʻopaʻa Resin T3; Lawe ka resin T3; Lākiō paʻa hormonone paʻa
- Hōʻaʻo koko
ʻO Guber HA, Farag AF. ʻO ka loiloi o ka hana endocrine. I: McPherson RA, Pincus MR, hua. ʻO kā Henry's Clinical Diagnosis a me Management e nā Laboratory Methods. 23rd Ed. St Louis, MO: Elsevier; 2017: chap 24.
ʻO Kiefer J, Mythen M, Roizen MF, Fleisher LA. Nā hopena anesthetic o nā maʻi like. I: Gropper MA, ed. Miller Anesthesia. 9th ed. Piladelapia, PA: Elsevier; 2020: chap 32.
ʻO Salvatore D, Cohen R, Kopp PA, Larsen PR. ʻO ka thyroid pathophysiology a me ka loiloi diagnostic. I: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. ʻO Williams Textbook of Endocrinology. 14th ed. Piladelapia, PA: Elsevier; 2020: chap 11.
Weiss RE, Refetoff S. Ke hoʻāʻo nei kāu hana thyroid. I: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Makua a Pediatric. ʻEpekema 7 Piladelapia, PA: Elsevier Saunders; 2016: chap 78.