ʻO ka hoʻopiʻi oligoclonal CSF

ʻO ka CSF oligoclonal banding kahi hoʻāʻo e nānā i nā protein pili i ka mumū i ka wai cerebrospinal (CSF). ʻO CSF ka wai aniani e kahe ana i kahi e puni ana i ka iwi kuamoʻo a me ka lolo.

ʻO nā hui Oligoclonal nā protein i kapa ʻia immunoglobulins. ʻO ke kū ʻana o kēia mau protein i hōʻike i ka mumū o ka ʻōnaehana waena. Ke kuhikuhi nei nā hui oligoclonal i kahi kuhi o nā sclerosis he nui.

Pono kahi laʻana o CSF. ʻO kahi lumbar puncture (spinal tap) ke ala maʻamau e hōʻiliʻili i kēia hāpana.

ʻAʻole hoʻohana iki ʻia nā ʻano hana ʻē aʻe no ka hōʻiliʻili ʻana iā CSF, akā paipai ʻia paha i kekahi mau hihia. Pākuʻi ʻia lākou:

• Pahu Cisternal
• Pahu hoʻokiwikā
• ʻO ka hemo ʻana o CSF ​​mai kahi ʻōmole i kū i ka CSF, e like me ka shunt a i ʻole ka ʻau ventricular.

Ma hope o ka lawe ʻia ʻana o kahi laʻana, hoʻouna ʻia i kahi lab no ka hoʻāʻo ʻana.

Kōkua kēia hōʻike i ke kākoʻo ʻana i ke kuhi o nā sclerosis (MS) he nui. Eia naʻe, ʻaʻole ia e hōʻoia i ke kuhi. ʻIke ʻia nā hui Oligoclonal i ka CSF i nā maʻi ʻē aʻe e like me:

• ʻO ka lupus erythematosus ʻōnaehana
• ʻO ka maʻi hoʻomaʻemaʻe kanaka (HIV) kanaka
• Hahau

ʻO ka maʻamau, loaʻa i hoʻokahi a ʻaʻohe paha nā kaula i ka CSF.

Kaha: hiki ke loli iki i nā pae waiwai maʻamau ma waena o nā hale hana ʻokoʻa. E kamaʻilio me kāu mea mālama ola e pili ana i ke ʻano o kāu mau hopena hōʻike kikoʻī.

Hōʻike nā hiʻohiʻona ma luna i nā ana maʻamau no nā hopena no kēia mau hoʻāʻo. Hoʻohana kekahi mau keʻena hoʻokolohua i nā ana like ʻole a i ʻole hoʻokolohua i nā hoʻohālikelike like ʻole.

ʻElua a ʻoi paha nā banding i loaʻa ma ka CSF a ʻaʻole i loko o ke koko. He hōʻailona paha kēia o nā sclerosis maha a i ʻole nā ​​mumū ʻē aʻe.

ʻO ka wai Cerebrospinal - pale pilikino

• Hoʻolālā CSF oligoclonal - moʻo
• Lumbar puncture (iwi kuamoʻo tap)

ʻO Deluca GC, ʻo Griggs RC. Hele i ka mea maʻi me ka maʻi neurologic. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 26th ed. Piladelapia, PA: Elsevier; 2020: chap 368.

ʻO Karcher DS, McPherson RA. Cerebrospinal, synovial, wai serous kino, a me nā mea i koho ʻia. I: McPherson RA, Pincus MR, hua. ʻO kā Henry's Clinical Diagnosis a me Management e nā Laboratory Methods. 23rd Ed. St Louis, MO: Elsevier; 2017: chap 29.