Immunoelectrophoresis - koko

ʻO Serum immunoelectrophoresis kahi hōʻike lab e ana i nā proteins i kapa ʻia immunoglobulins i loko o ke koko. ʻO nā Immunoglobulins nā protein i hana e like me nā mea ʻohā, e hakakā ana i ka maʻi. Nui a hewahewa nā ʻano immunoglobulins e hakakā me nā ʻano maʻi like ʻole. Hiki i kekahi immunoglobulins ke kino a ma muli paha o ka maʻi ʻaʻai.

Hiki ke ana ʻia ʻo Immunoglobulins i ka mimi.

Pono kahi laʻana koko.

ʻAʻohe hoʻomākaukau kūikawā no kēia hōʻike.

Ke hoʻokomo ʻia ke kui kele e huki i ke koko, manaʻo kekahi poʻe i ka ʻeha kaulike. ʻIke wale kekahi i kahi ʻōniʻu a i ʻole kui. Ma hope, loaʻa paha i kahi kūpikipiki a i ʻole ʻeha iki. Hele koke kēia.

Hoʻohana pinepine ʻia kēia hoʻāʻo e nānā i nā pae o nā antibodies ke loaʻa a kuhi ʻia paha kekahi mau maʻi ʻino a me nā maʻi ʻē aʻe.

ʻO kahi hopena maʻamau (maikaʻi ʻole) ke ʻano o ka laʻana o ke koko i ʻano maʻamau o immunoglobulins. ʻAʻole kiʻekiʻe ke kiʻekiʻe o hoʻokahi immunoglobulin ma mua o nā mea ʻē aʻe.

Nā hopena kūpono ʻole ma muli o:

• Myeloma maha (kahi ʻano maʻi ʻaʻai koko)
• Leukemia lymphocytic mau a i ʻole Waldenström macroglobulinemia (ʻano o nā maʻi ʻaʻai keokeo keokeo)
• Amyloidosis (kūkulu ʻia o nā protein pono ʻole i nā aʻa a me nā meaola)
• Lymphoma (maʻi 'aʻai o ka lymphʻaʻaʻa)
• Hewa ʻole nā ​​hakuʻala
• Maʻi kīnā

Loaʻa i kekahi poʻe nā immunoglobulins monoclonal, akā ʻaʻohe o lākou maʻi ʻaʻai. Kāhea ʻia kēia monoclonal gammopathy o ka waiwai ʻike ʻole ʻia, a me MGUS.

ʻAʻohe pilikia iki i ka lawe ʻia ʻana o kou koko. ʻOkoʻa nā aʻa a me nā aʻa i ka nui mai kekahi kanaka a i kekahi ʻē aʻe a mai kekahi ʻaoʻao o ke kino i kekahi. ʻOi aku ka paʻakikī o ka lawe ʻana i ke koko mai kekahi poʻe ma mua o nā poʻe ʻē aʻe.

ʻO nā pilikia ʻē aʻe e pili ana i ke kau ʻana o ke koko he liʻiliʻi, akā hiki ke hoʻopili ʻia:

• Kahe nui ke koko
• Pāleʻale a ʻoluʻolu paha
• Nā punctures he nui e ʻimi i nā uaua
• Hematoma (hōʻiliʻili koko ma lalo o ka ʻili)
• Maʻiʻaʻai (i iki kamepiula i kēlā me kēia manawa ka ʻili i haki)

IEP - serum; Immunoglobulin electrophoresis - koko; Gamma globulin electrophoresis; Serum immunoglobulin electrophoresis; ʻO Amyloidosis - serum electrophoresis; Myeloma maha - electrophoresis serum; Waldenström - nā electrophoresis serum

• Hōʻaʻo koko

Aoyagi K, Ashihara Y, Kasahara Y. Immunoassays a me immunochemistry. I: McPherson RA, Pincus MR, hua. ʻO kā Henry's Clinical Diagnosis a me Management e nā Laboratory Methods. 23rd Ed. St Louis, MO: Elsevier; 2017: chap 44.

Kricka LJ, Pāka JY. Nā hana Immunochemical. I: Rifai N, ed. ʻO Tietz Textbook of Clinical Chemistry a me nā Molecular Diagnostics. ʻElua huaʻōlelo St Louis, MO: Elsevier; 2018: chap 23.