ʻO ka CSF myelin protein kumu
ʻO ka CSF myelin kumuʻiʻo kumuʻiʻo kahi hōʻike e ana i ka pae o ka myelin kumuʻiʻo protein (MBP) i ka cerebrospinal fluid (CSF).
He wai maopopo ʻo CSF e hoʻopuni ana i ka lolo a me ka iwi kuamoʻo.
Loaʻa ka MBP i nā mea e uhi ana i ka nui o kou aʻa.
Pono kahi laʻana o ka wai spinal. Hana ʻia kēia me ka puncture lumbar.
Hana ʻia kēia hōʻike e ʻike inā e haki ana ka myelin. ʻO ka sclerosis Multiple ka kumu maʻamau o kēia, akā ʻo nā kumu ʻē aʻe e komo pū:
- Kahe ʻana o ka ʻōnaehana waena
- Trauma ʻōnaehana waena
- Kekahi maʻi lolo (encephalopathies)
- ʻO ka maʻi o ke kikowaena ʻōnaehana
- Hahau
Ma ka laulā, pono e emi ma lalo o 4 ng / mL o ka myelin kumuʻiʻo protein i ka CSF.
Hiki ke loli iki nā pae waiwai maʻamau i waena o nā hale hana ʻokoʻa. E kamaʻilio me kāu mea mālama ola e pili ana i ke ʻano o kāu mau hopena hōʻike kikoʻī.
Hōʻike ka laʻana ma luna i nā hopena ana maʻamau no kēia hoʻāʻo. Hoʻohana kekahi mau keʻena hoʻokolohua i nā ana like ʻole a i ʻole hoʻokolohua i nā hoʻohālikelike like ʻole.
Myelin kumuʻiʻo pae pae ma waena o 4 a me 8 ng / mL paha he hōʻailona o kahi wā lōʻihi (mau) breakdown o ka myelin. Hōʻike paha ia i ka hoʻōla ʻia mai kahi ʻāpana koʻikoʻi o ka myelin breakdown.
Inā ʻoi aku ka nui o ka nui o ka protein protein ma mua o 9 ng / mL, ke haki nui nei ʻo myelin.
- Lumbar puncture (iwi kuamoʻo tap)
Fabian MT, Krieger SC, Lublin FD. ʻO nā sclerosis he nui a me nā maʻi demyelinating maha o ka ʻōnaehana waena. I: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, eds. ʻO Bradley's Neurology i ka hana lapaʻau. ʻEpekema 7 Piladelapia, PA: Elsevier; 2016: chap 80.
ʻO Karcher DS, McPherson RA. Cerebrospinal, synovial, wai serous kino, a me nā mea i koho ʻia. I: McPherson RA, Pincus MR, hua. ʻO kā Henry's Clinical Diagnosis a me Management e nā Laboratory Methods. 23rd Ed. St Louis, MO: Elsevier; 2017: chap 29.