Choriocarcinoma

ʻO Choriocarcinoma kahi maʻi ʻaʻai e ulu wikiwiki ana i loko o ka wahine kōpū (ʻōpū). Hoʻomaka nā hunaola ʻino i loko o ka aʻa e lilo i placenta. ʻO kēia ka lālā e hoʻomohala i ka wā hāpai e hānai i ka ʻōpū.

ʻO Choriocarcinoma kahi ʻano maʻi trophoblastic hāpai.

ʻO Choriocarcinoma kahi maʻi ʻaʻai laha ʻole e kū ʻia ma ke ʻano he hāpai hāpai ʻole. Hiki paha a ulu ʻole paha kahi pēpē i kēia ʻano hāpai.

Hiki ke kū i ka maʻi ʻaʻai ma hope o ka hāpai maʻamau. Akā pinepine pinepine ia me kahi mole hydatidiform piha. ʻO kēia kahi ulu ulu i loko o ka ʻōpū i ka hoʻomaka o kahi hāpai. Hiki ke hoʻomau i ka ulu o nā mākala mai ka mole e ulu a hiki i ka hoʻāʻo ʻana e hemo, a hiki ke lilo i maʻi ʻaʻai. Ma kahi o ka hapalua o nā wahine āpau me kahi choriocarcinoma i loaʻa i kahi mole hidatidiform, a i ʻole hāpai hāpai molar.

Hiki i nā Choriocarcinomas ke hana ma hope o ka hāpai mua ʻana e hoʻomau ʻole (hāʻule ʻole). Hiki iā lākou ke hana ma hope o ka hāpai ʻana ectopic a i ʻole ka tumo genital.

ʻO kahi ʻōuli kūpono a kūpono ʻole a kolohe ʻole paha o ke kahe i loko o ka wahine i loaʻa i kahi mole hidatidiform a i ʻole hāpai.

Hiki i nā ʻōuli ʻē aʻe ke:

• Kahe koko
• ʻEha, i pili pū ʻia me ke kahe ʻana o ke koko, a i ʻole no ka hoʻonui ʻia ʻana o nā ovaries e hana pinepine ʻia me kahi choriocarcinoma.

E maikaʻi kahi hōʻoia hāpai, ʻoiai inā ʻaʻole hāpai ʻoe. E kiʻekiʻe ka pae kōpū (HCG).

ʻIke paha kahi hōʻike pelvic i kahi uterus hoʻonui ʻia a me nā ovaries.

Hiki ke hana ʻia nā hoʻokolohua koko e:

• ʻO ka HCG serum nui
• Helu piha koko
• Nā hoʻāʻo hana hakuʻala
• Nā hoʻāʻo hana ate

ʻO nā hoʻokolohua kiʻi ʻana i hana ʻia e hoʻopili ʻia:

• CT scan
• MRI
• Pelvic ultrasound
• Pākuʻi x-ray

E kiaʻi pono ʻia ʻoe ma hope o kahi mole hydatidiform a i ʻole ka hopena o kahi hāpai. Hiki i ka ʻike mua o choriocarcinoma ke hoʻomaikaʻi i ka hopena.

Ma hope o kou kuhi ʻia ʻana, e hana ʻia kahi mōʻaukala akahele a me ka hoʻāʻo e hōʻoia i ka palahalaha ʻole o ka maʻi ʻaʻai i nā meaola ʻē aʻe. ʻO Chemotherapy ka ʻano nui o ka mālama ʻana.

Hysterectomy e hemo i ka ʻōpū a me ka mālama ʻana i ka radiation ʻaʻole makemake iki ʻia.

Hiki iā ʻoe ke hoʻomāmā i ke koʻikoʻi o ka maʻi ma ke komo ʻana i kahi hui kākoʻo maʻi ʻaʻai. ʻO ke kaʻana ʻana me nā poʻe ʻē aʻe i loaʻa nā ʻike a me nā pilikia maʻamau e hiki ke kōkua iā ʻoe e noʻonoʻo ʻole.

ʻO ka hapanui o nā wahine ʻaʻole pālahalaha ka maʻi ʻaʻai hiki ke hoʻōla a hiki ke loaʻa nā keiki. Hiki ke hoʻi i kahi choriocarcinoma i loko o kekahi mau mahina i 3 mau makahiki ma hope o ka lapaʻau.

ʻOi aku ka paʻakikī o ke ʻano e hōʻola inā ua laha ka maʻi ʻaʻai a hoʻokahi a ʻoi paha o nā mea aʻe e hiki mai ana:

• Hoʻolahalaha ka maʻi i ke ake a i ʻole ka lolo
• ʻOi aku ka kiʻekiʻe o ka hormone hāpai (HCG) ma mua o 40,000 mIU / mL ke hoʻomaka ka lāʻau
• Hoʻi ka maʻi ʻaʻai ma hope o ka loaʻa ʻana o ka chemotherapy
• Ua loaʻa nā ʻōuli a i ʻole hāpai hāpai ma mua o 4 mau mahina ma mua o ka hoʻomaka ʻana o ka mālama ʻana
• Ua loaʻa ʻo Choriocarcinoma ma hope o ka hāpai ʻana i hopena i ka hānau ʻana o kahi keiki

Nui nā wahine (ma kahi o 70%) i loaʻa kahi nānā maikaʻi ʻole i ka mua e hele i ke kala ʻana (kahi ʻano maʻi ʻole).

Kāhea i kahi manawa me kāu kauka olakino inā ʻoe e hoʻomohala i nā hōʻailona ma waena o 1 mau makahiki ma hope o ka mole hydatidiform a i ʻole hāpai.

Chorioblastoma; ʻŌpū Trophoblastic; Chorioepithelioma; Neoplasia trophoblastic Gestational; Kanesa - choriocarcinoma

Pūnaewele ʻo National Cancer Institute. Hoʻoponopono maʻi trophoblastic Gestational (PDQ) - mana ʻoihana olakino. www.cancer.gov/cancertopics/pdq/treatment/gestationaltrophoblastic/HealthProfessional. Hoʻohou i Kēkēmapa 17, 2019. Loaʻa iā Iune 25, 2020.

Salani R, Bixel K, Copeland LJ. Nā maʻi kūpilikiʻi a me ka hāpai keiki. I: Landon MB, Galan HL, Jauniaux ERM, et al, eds. Nā Kāpena Gabbe: Nā Pregnancies Maʻamau a me nā Pilikia. ʻEpekema 7 Piladelapia, PA: Elsevier; 2021: chap 55.