Koho kūpono o IgA

ʻO ka hemahema koho o IgA ka maʻi maʻi pale maʻi maʻamau loa. Loaʻa ka poʻe me kēia maʻi i kahi pae haʻahaʻa a i ʻole absent o kahi protein protein i kapa ʻia immunoglobulin A.

Ua hoʻoili ʻia ka hemahema IgA, ʻo ia hoʻi ua hoʻoili ʻia i waena o nā ʻohana. Eia nō naʻe, aia kekahi mau hihia o ka hemahema IgA i hoʻokomo ʻia i ka lāʻau.

Hiki ke hoʻoili ʻia ma ke ʻano he autosomal dominant a autosomal recessive paha. ʻIke ʻia ia i ka poʻe o ko ʻEulopa kumu. ʻAʻole liʻiliʻi ia i nā poʻe o nā lāhui ʻē aʻe.

Nui nā poʻe me ka hemahema IgA koho ʻole ʻia nā ʻōuli.

Inā loaʻa nā ʻōuli o kekahi kanaka, hiki iā lākou ke hoʻopili i nā ʻāpana pinepine o:

• Bronchitis (maʻi lele)
• Pohā ʻōpū
• Conjunctivitis (maka maʻi)
• ʻO ka mumū Gastrointestinal, me ke kolitis ulcerative, ka maʻi Crohn, a me kahi maʻi like sprue
• Maʻi maʻi o ka waha
• Otitis media (ma waena o ka pepeiao maʻiʻaʻai)
• Ponia (maʻi hū)
• Sinusitis (sinus maʻiʻaʻai)
• Nā maʻi ʻili
• ʻO nā maʻi maʻi hanu luna

ʻO nā ʻōuli ʻē aʻe e like me:

• ʻO Bronchiectasis (kahi maʻi kahi e ʻino ai a hoʻonui ʻia ai nā ʻeke ea liʻiliʻi i nā akemāmā)
• Asthma me ke kumu ʻole i ʻike ʻia

Aia paha he moʻolelo ʻohana o ka hemahema IgA. ʻO nā hoʻāʻo e hana ʻia ana paha:

• Nā ana ma lalo o ka IgG
• Nā immunoglobulins nui
• Serum immunoelectrophoresis

ʻAʻole loaʻa kahi lapaʻau kūikawā. Hoʻolālā mālie kekahi poʻe i nā pae maʻamau o IgA me ka ʻole o ka lāʻau.

Hoʻopili ka mālama ʻana i nā hana e hōʻemi ai i ka helu a me ke koʻikoʻi o nā maʻi. Pono pinepine nā lāʻau antibiotic e mālama i nā maʻi bacteria.

Hāʻawi ʻia nā Immunoglobulins ma o ke aa a i ʻole ke kuʻi ʻana e hoʻonui i ka ʻōnaehana pale.

Hoʻokumu ʻia ka mālama maʻi maʻi autoimmune i ka pilikia kikoʻī.

Kaha: ʻO ka poʻe me ka hemahema IgA piha e hoʻomohala i nā anti-IgA antodies inā hāʻawi ʻia nā huahana koko a me nā immunoglobulins. Hiki i kēia ke alakaʻi i nā maʻi āpau a i ʻole ka weliweli anaphylactic hoʻoweliweli ola. Eia nō naʻe, hiki iā lākou ke hāʻawi palekana iā lākou i nā immunoglobulins i hoʻopau ʻia e IgA.

ʻOi aku ka maikaʻi o ka hemahema SelA Igative ma mua o ka nui o nā maʻi āpau.

ʻO kekahi poʻe me ka hemahema IgA e hoʻihoʻi iā lākou iho a hana IgA i nā nui he nui i kahi mau makahiki.

Hiki ke ulu i nā maʻi autoimmune e like me ka rheumatoid arthritis, ka systemic lupus erythematosus, a me ka celiac sprue.

Hiki i nā poʻe me ka hemahema IgA ke hoʻomohala i nā mea pale i IgA. ʻO ka hopena, hiki iā lākou ke loaʻa i nā hopena koʻikoʻi, a hoʻoweliweli hoʻi i ke ola i nā transfusions o ke koko a me nā huahana koko.

Inā loaʻa iā ʻoe kahi hemahema IgA, e hoʻomaopopo pono e haʻi iā ia i kāu kauka olakino inā e ʻōlelo ʻia ʻo immunoglobulin a i ʻole nā ​​transfusions ʻē aʻe o ke koko ma ke ʻano he lapaʻau no kēlā me kēia ʻano.

He mea waiwai paha ke aʻo aʻoaʻo kūlohelohe i nā mākua e hiki mai ana me ka moʻolelo ʻohana o ka hemahema IgA koho.

Hemahema IgA; Immunodepressed - hemahema IgA; Immunosuppressed - IgA hemahema; Hypogammaglobulinemia - hemahema IgA; Agammaglobulinemia - hemahema IgA

• Nā Antibodies

ʻO Cunningham-Rundles C. Nā maʻi pale maʻi ʻole. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 26th ed. Piladelapia, PA: Elsevier; 2020: chap 236.

Sullivan KE, ʻO Buckley RH. Nā kīnā mua o ka hana antibody. I: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. ʻO Puka Textbook of Pediatrics ʻo Nelson. 21st ed. Piladelapia, PA: Elsevier; 2020: chap 150.