Maʻi maʻi

ʻO ka maʻi serum kahi hopena e like me ka maʻi āpau. Hana ka ʻōnaehana pale i nā lāʻau i loaʻa nā protein i hoʻohana ʻia e mālama i nā kūlana pale. Hiki iā ia ke pane i ka antiserum, ka ʻāpana wai o ke koko i loaʻa i nā mea ʻino i hāʻawi ʻia i kahi kanaka e kōkua e pale iā lākou mai nā mikamina a i nā lāʻau ʻona.

ʻO ka Plasma ka ʻāpana kahe maopopo o ke koko. ʻAʻole i loaʻa nā huna koko. Akā loaʻa iā ia i loko o nā protein, me nā antibodies, i hana ʻia ma ke ʻāpana o ka pane pale pale e pale ai i ka maʻi.

Hana ʻia ʻo Antiserum mai ka plasma o kahi kanaka a holoholona paha i loaʻa ka pale ʻana i ka maʻi a i ʻole ka lāʻau make. Hiki ke hoʻohana ʻia ʻo Antiserum e pale aku i kahi kanaka i hōʻike ʻia i ka germ a i ka lāʻau make paha. ʻO kahi laʻana, loaʻa paha iā ʻoe kahi ʻano o ka hoʻopili antiserum:

• Inā ua hōʻike ʻia ʻoe i ka tetanus a i ʻole nā ​​rabies a ʻaʻole i hana ʻona iā ʻoe i kēia mau maʻi. Kapa ʻia kēia ʻo ka pale ʻana i ka passive.
• Inā ua nahu ʻia ʻoe e ka nahesa e hoʻopuka i kahi lāʻau make weliweli.

I ka manawa o ka maʻi serum, ʻike hewa ka ʻōnaehana pale i kahi protein i loko o antiserum ma ke ʻano he mea ʻino (antigen). ʻO ka hopena he pane ʻōnaehana pale pale nāna e hoʻouka i ka antiserum. Hui pū nā ʻōnaehana ʻōnaehana a me ka antiserum e hana i nā complexes immune, i kumu i nā ʻōuli o ka maʻi serum.

Hiki i kekahi mau lāʻau (e like me ka penicillin, cefaclor, a me ka sulfa) ke hana i kahi ʻano like.

ʻO nā protein i hoʻopili ʻia e like me antithymocyte globulin (hoʻohana ʻia e mālama i ka hōʻole ʻana i nā mea hoʻoneʻe) a me rituximab (hoʻohana ʻia e mālama i nā maʻi pale a me nā maʻi ʻaʻai) hiki ke hana i nā maʻi maʻi serum.

Hiki i nā huahana koko ke kumu i ka maʻi serum.

ʻAʻole like me nā lāʻau āpau ʻē aʻe, i ka wā koke ma hope o ka loaʻa ʻana o ka lāʻau, hoʻomohala ka maʻi serum 7 a 21 mau lā ma hope o ka hōʻike mua ʻana i ka lāʻau. Hoʻolālā kekahi poʻe i nā ʻōuli ma 1 a 3 mau lā inā ua hōʻike mua ʻia i ka lāʻau.

Hiki i nā ʻōuli o ka maʻi serum ke komo pū me:

• Fiva
• Manaʻo maʻi laulā
• ʻO Hives
• Kāwili
• ʻEha hui
• Rash
• Nā pehu lymph pehu

E hana ka mea mālama ola i kahi hoʻokolohua e nānā no nā lymph node i hoʻonui ʻia a palupalu i ka pā.

ʻO nā hoʻāʻo e hana ʻia ana paha:

• Hōʻike mimi
• Hōʻaʻo koko

ʻO nā lāʻau lapaʻau, e like me nā corticosteroids, i hoʻopili ʻia i ka ʻili e hōʻoluʻolu paha i ka hōʻoluʻolu mai ka huehue a me ka hū.

Hiki i nā Antihistamines ke hoʻopōkole i ka lōʻihi o ka maʻi a kōkua i ka hoʻomaʻalahi ʻana i ka hū a me ka ʻili.

ʻO nā lāʻau anti-inflammatory Nonsteroidal (NSAIDs), e like me ka ibuprofen a i ʻole naproxen, hiki ke hoʻomaha i ka ʻeha pū. Hiki ke kuhikuhi ʻia nā Corticosteroids e ka waha no nā hihia koʻikoʻi.

ʻO ka lāʻau i hana i ka pilikia e pono e hoʻopau. Hōʻalo i ka hoʻohana ʻana i kēlā lāʻau lapaʻau a i ʻole antiserum i ka wā e hiki mai ana.

Hele pinepine nā ʻōuli i loko o kekahi mau lā.

Inā ʻoe e hoʻohana i ka lāʻau a i ʻole antiserum i hoʻokumu hou i ka maʻi serum i ka wā e hiki mai ana, kiʻekiʻe kou makaʻu i ka loaʻa ʻana o kahi ʻano like.

Komo pū nā pilikia:

• ʻO ka hoʻowahāwahā o nā kīʻaha koko
• ʻO ka pehu ʻana o ka maka, nā lima, a me nā wāwae (angioedema)

Kāhea i kāu mea hāʻawi inā loaʻa ka lāʻau a i ʻole antiserum i nā pule he 4 i hala iho nei a loaʻa nā hōʻailona o ka maʻi serum.

ʻAʻohe ala i ʻike ʻia e pale ai i ka ulu ʻana o ka maʻi serum.

ʻO ka poʻe i loaʻa i ka maʻi serum a i ʻole ka hoʻowalewale lāʻau e hōʻalo i ka hoʻohana ʻana o ka antiserum a i ʻole ka lāʻau.

ʻAha maʻi ʻaʻai - maʻi serum; Hoʻoiho kūlohelohe - maʻi serum; ʻAhaʻi - maʻi maʻi

• Nā Antibodies

ʻO Frank MM, Hester CG. Nā pilikia Immune a me nā maʻi maʻi. I: Burks AW, Holgate ST, O'Hehir RE, et al, eds. Middleton's Allergy: Nā Manaʻo a me ka Hoʻomaʻamaʻa. 9th ed. Piladelapia, PA: Elsevier; 2020: chap 37.

ʻO Nowak-Wegrzyn A, ʻo Sicherer SH. Maʻi maʻi. I: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. ʻO Puka Textbook of Pediatrics ʻo Nelson. 21st ed. Piladelapia, PA: Elsevier; 2020: chap 175.